한양방치료를 병행한 안성 대상포진 환자 치험 1례

박민정,양정윤,김수현,조기호,문상관,권승원,정우상,Park, Min-jeong,Yang, Jung-yun,Kim, Soo-hyun,Cho, Ki-ho,Moon, Sang-kwan,Kwon, Seung-won,Jung, Woo-sang 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.2

A case of a 72-year-old Korean male with herpes zoster ophthalmicus revealed. He was treated with Korean-Western cooperative treatment. We used the Numeric Rating Scale (NRS) to evaluate forehead and eye pain. Pain was improved after the administration of Korean medical treatments and disappeared after eight days. Korean-Western cooperative treatment may be effective in treating acute herpes zoster ophthalmicus.

졸-겔법에 의한 나노크기 Au 미립자 분산 TiO₂ 박막의 특성

박민정,구세나,이경석,문종수,Park, Min-Jung,Koo, Se-Na,Lee, Kyoung-Seok,Mun, Chong-Soo 한국세라믹학회 2006 한국세라믹학회지 Vol.43 No.2

Nano-size Au particle doped $TiO_2$ films were prepared with $Ti(OC_3H_7^i)_4$, polyvinylpyrrolidone(PVP), $HAuCl_4$ and $C_3H_7OH$ etc. by sol-gel method. $TiO_2$ gel films were obtained by the dip-coating method on the $SiO_2$ glass substrates, and then heat-treated at $700^{\circ}C$ for 10 min. The thickness of $TiO_2$ films were $0.7\~1.8\;{\mu}m$. It was found that the thickness of films prepared from PVP containing solution was about $2\~8$ times higher values than that of thin films without PVP. The size of Au particles doped in the films were about $350\~750\;nm$. Nano-size Au particle dispersed $TiO_2$ films showed high absorption peak at visible region 450nm, which made them good candidates for non-linear optical materials and photo-catalytic materials. The contact angle of $TiO_2$ film for water was $12.5^{\circ}$, and therefore it is clear that $TiO_2$ films have very high hydrophilic properties and the self-cleaning effects.

갈색 느티만가닥버섯 추출물의 부위별 항산화 활성

박민정,유찬열,조수정,Park, Min Jeong,Yu, Chan Yeol,Cho, Soo Jeong 한국버섯학회 2021 한국버섯학회지 Vol.19 No.4

본 연구에서는 기능성 식의약품 소재로써 갈색 느티만가닥버섯(Hypsizygus marmoreus)의 이용 가능성을 조사하기 위해 갈색 느티만가닥버섯의 부위별, 추출 용매별 항산화 활성을 조사하였다. 열수 추출물 갓과 대의 총 폴리페놀 함량은 17.15±0.19 mg GAE/g과 7.37±0.16 mg GAE/g이었으며 에탄올 추출물 갓과 대의 총 폴리페놀 함량은 각각 10.23±0.14 mg GAE/g과 3.76.±0.19 mg GAE/g으로 에탄올 추출물에 비해 열수 추출물의 폴리페놀 함량이 높게 나타났고 대에 비해 갓의 폴리페놀 함량이 높게 나타났다. 또한 갈색 느티만가닥버섯 추출물의 DPPH, ABTS, ORAC 지수, 환원력도 10 mg/ml의 농도에서 에탄올 추출물에 비해 열수 추출물에서 높게 나타났고 대에 비해 갓에서 높게 나타났으며 흰색 느티만가닥버섯에 비해 갈색 느티만가닥버섯의 총 폴리페놀 함량, DPPH, ORAC 지수, 환원력이 높은 것으로 나타났다. 추출물의 세포독성은 WST-1 assay (4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene disulphonate)를 이용하여 열수 추출물의 처리 농도에 따른 대식세포주 RAW 264.7의 세포 생존율로 확인하였으며 갈색 느티만가닥버섯 열수 추출물 처리구에서 대식세포주 RAW 264.7의 세포 생존율이 증가하였기 때문에 세포독성은 없는 것으로 판단된다. 이상의 결과를 종합하면, 느티만가닥버섯은 품종에 따라 항산화 활성에 차이가 있고, 갈색 느티만가닥버섯은 다른 버섯보다 항산화 활성이 높기 때문에 기능성 식의약품 소재로서 이용 가능성이 있다고 판단된다. This study was carried out to evaluate potential of Hypsizygus marmoreus (brown cultivar) as a functional food and drug materials. H. marmoreus were divided into pileus and stipe and extracted in hot water and 80% ethanol. The total polyphenol content was highest in the hot water extracts (pileus 17.15±0.19 mg of GAE g, stipe 7.37±0.16 mg of GAE/g) and pileus compared to the ethanol extracts (pileus 10.23±0.14 mg of GAE/g, stipe 3.76.±0.19 mg of GAE/g) and stipe. Also, hot water extracts of pileus from H. marmoreus (brown cultivar) was more effective DPPH, ABTS, ORAC value, reducing power than ethanol extracts and stipe extracts. The pileus and stipe extracts were confirmed to be non-cytotoxic in the mouse macrophage cell line RAW 264.7 determined by WST-1 (4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene disulphonate) assay. Overall, extracts of H. marmoreus (brown cultivar) was higher antioxidant activity than other mushrooms, and no cytotoxicity. Therefore, H. marmoreus (brown cultivar) showed potential as a functional food and drug materials. The brown cultivar of H. marmoreus have higher antioxidant activity than white cultivar, H. marmoreus seem to have different antioxidant activity depending on the cultivar.

불면을 호소하는 Lewy's body dementia 환자 치험 1례

박민정,이미림,김경묵,조기호,문상관,권승원,정우상,Park, Min-jeong,Lee, Mi-rim,Kim, Gyeong-muk,Cho, Ki-ho,Moon, Sang-kwan,Kwon, Seung-won,Jung, Woo-sang 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.2

The patient was a 69-year-old Korean male with Lewy's body dementia and insomnia. He was treated with acupuncture and a herbal medicine, Ukan-san. To evaluate insomnia, the patient's total sleeping time was recorded. The patient's sleeping time increased after the administration of the Korean medicine treatments. Treatment with Korean medicine may be effective in treating insomnia in cases of Lewy's body dementia.

위천공 수술 후 발생한 난치성 딸꾹질을 호소하는 환자 치험 1례

박민정,손정화,우지명,조기호,정우상,문상관,Park, Minjeong,Son, Jeonghwa,Woo, Ji Myoug,Cho, Ki-ho,Jung, Woo-sang,Moon, Sang-kwan 대한중풍순환신경학회 2016 대한중풍.순환신경학회지 Vol.17 No.1

■ Objectives The purpose of this clinical study is to evaluate the effect of Korean Medical Treatment on a 71 years old Korean male with Intractable hiccup for 40 years after gastric perforation operation. ■ Methods He was treated with acupuncture, electroacupuncture, moxibustion and herbal medicine, Jakyakgamcho-tang and Banhasasim-tang. We evaluated the improvement by frequency of hiccup and NRS of hiccup. ■ Results Hiccup disappeared at sixth day of treatment and NRS of hiccup also decreased.. ■ Conclusion Korean medical treatment may be effective in treating intractable hiccup

우리나라 에코세대의 자살생각과 관련요인: 2012년도 한국의료패널 자료를 이용하여

박민정,Park, Min Jeong 한국가정간호학회 2016 가정간호학회지 Vol.23 No.1

Purpose: This study investigated the factors associated with suicidal ideation in the Korean Echo Generation using 2012 Korea Health Panel Data. Methods: The 2012 Korea Health Panel Data were collected from February 2012 to July 2012 and included 2,303 people who responded to a question asking whether they had experienced suicidal ideation. The data were analyzed by chi-square and multiple logistic regression test using SPSS 22.0. Results: The rate of suicidal ideation was 4.2% in the Echo Generation. Factors associated with suicidal ideation in the Echo Generation revealed that the following variables increased the rate of suicidal ideation: sex(odd ratio: 2.39, CI: 1.39-4.09), education(odd ratio: 1.95, CI: 1.08-3.52), depression(odd ratio: 12.06, CI: 6.92-21.03), frustrating experience(odd ratio: 2.52, CI: 1.22-5.20), anxiety about the future(odd ratio: 14.58, CI: 3.20-66.41), self-rated health status(odd ratio: 2.39, CI: 1.39-4.09 and odd ratio: 6.41, CI 2.87-14.33). Conclusion: This study provides a preliminary examination of the factors associated with suicidal ideation in the Echo Generation. A more careful examination may be warranted.

순환성분 추출을 위한 EMD와 HP 필터의 비교분석: 한국의 거시 경제 지표에의 응용

박민정,성병찬,Park, Minjeong,Seong, Byeongchan 한국통계학회 2014 응용통계연구 Vol.27 No.3

본 논문에서는 시간-진동수 영역에서 시계열을 여러 구성 성분으로 분해하는 방법인 경험적모드분해법(Empirical Mode Decomposition)을 소개하고, 이를 이용하여 한국의 주요 거시 경제 지표를 대상으로 순환변동과 추세 성분을 추출하고 예측에 활용한다. 그 효율성을 살펴보기 위하여, 추출된 구성 성분들의 변동성, 동행성, 지속성, 인과성, 비정상성 및 예측력을 계산하고, 가장 보편적으로 널리 사용되고 있는 Hodrick-Prescott 필터에 의한 결과와 비교한다. We introduce the empirical model decomposition (EMD) to decompose a time series into a set of components in the time-frequency domain. By using EMD, we also extract cycle and trend components from major Korean macroeconomic indices and forecast the indices with the components combined. In order to evaluate their efficiencies, we investigate volatility, autocorrelation, persistence, Granger causality, nonstationarity, and forecasting performance. They are then compared with those by Hodrick-Prescott filter which is the most commonly used method.

퇴행성 슬관절염 환자에 대한 슬관절방(膝關節方) 1호(號)의 제형변화 유효성 임상연구

박민정,서진우,성인형,김남옥,성수민,정애경,신대희,박쾌환,Park, Min-Jung,Seo, Jin-Woo,Sung, In-Hyung,Kim, Nam-Ok,Sung, Su-Min,Chung, Ae-Kyung,Shin, Dae-Hee,Park, Koae-Hwan 대한한의학방제학회 2005 大韓韓醫學方劑學會誌 Vol.13 No.2

Objective: This study is designed to compare the effects of Sulguanjul-Bang No.1 on osteoarthritis in knee joint according to formulation. Methods: 47 patients with symptomatic osteoarthritis of the knee joint were enrolled in a open clinical trial. The 47 patients were devided into two groups at random and taken Sulguanjul-bang No.1 with decoction type, suspension type respectively for8 weeks. After 8-week treatment period, the following parameters were analyzed ; Visual analogue Scale(VAS), Lysholm index score, patients' global assessment. Results: Sulguanjul-bang No.1 treatment led to significant improvement in the pain and symptoms of osteoarthritis as determined by all efficacy measures. After 8 weeks of therapy, there was significant improvement in VAS, Lysholm index and patients' global assessment. But there is no significant difference between two groups. Conclusions: Sulguanjul-bang No.1 was very beneficial pain relief effect and functional improvement irrespect of formulation, decoction type or suspension type.

폐광산지역 토양 식생복원 과정 내 토양특성 및 미생물 군집 변화 분석

박민정,윤민호,남인현,Park, Min-Jeong,Yoon, Min-Ho,Nam, In-Hyun 한국지하수토양환경학회 2015 지하수토양환경 Vol.20 No.3

Mine soil contamination by high levels of metal ions that prevents the successful vegetation poses a serious problem. In the study presented here, we used the microbial biocatalyst of urease producing bacterium Sporosarcina pasteurii or plant extract based BioNeutro-GEM (BNG) agent. The ability of the biocatalysts to bioremediate contaminated soil from abandoned mine was examined by solid-state composting vegetation under field conditions. Treatment of mine soil with the 2 biocatalysts for 5 months resulted in pH increase and electric conductivity reduction compared to untreated control. Further analyses revealed that the microbial catalysts also promoted the root and shoot growth to the untreated control during the vegetation treatments. After the Sporosarcina pasteurii or plant extract based BNG treatment, the microbial community change was monitored by culture-independent pyrosequencing. These results demonstrate that the microbial biocatalysts could potentially be used in the soil bioremediation from mine-impacted area.

한.양방 협진의 진료협력수준 측정도구개발 및 타당도 연구

박민정,최병희,백윤희,박정혜,Park, Minjung,Choi, Byunghee,Baek, Yun Hui,Park, Jeong Hye 대한예방한의학회 2015 대한예방한의학회지 Vol.19 No.1

Objective : The purpose of this study is to present the desirable model for the promotion of care coordination between Korean Medicine and Western Medicine and develope the instrument to measure the level of coordination. Moreover, we verified the validity and reliability of the developed Instrument. Method : In this study, We developed the 16 items regarding care coordination in Korean Medicine and Western Medicine by literature review and expert interviews. In addition, we verified the validity and reliability of the instrument as a methodological research. Results : We developed two factors such as 'Inter-professional activities' and 'Organizational support' as the instrument to measure the level of care coordination, and each of seven, eight total of 15 measurement items are listed. Conclusion : Since the legal permission, the level and type of care coordination and the effects of them are needed to be checked. So, the measurement instrument driven by this study has a political signification in healthcare system specially in these times. In addition, by utilizing this instrument, we propose to perform a variety of future studies on the levels of healthcare coordination and related outcomes.