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박경식,강국희 한국낙농학회 1990 韓國酪農學會誌 Vol.12 No.4
본 연구는 우리나라 미숙 분만아의 생후 한달간 식이별 경시적 장내 균총의 변화와 분리 균속의 동정에 관한 연구로서 그 결과를 다음과 같이 요약할 수 있다. 1. 미숙 분만아의 모유 식이하의 장내 균총을 균속별로 보면 대체로 Bifidobacterium, Bacteroidaceae, Clostridium, Eubacterium, 그리고 Enterobacteriaceae의 순으로 나타났다. 2. 미숙분만아의 미숙아 분유 식이하의 장내균총을 균속별로 보면 Bifidobacterium, Enterobacteriaceae, Eubacterium, Bacteroidaceae 그리고 Clostridium의 순으로 나타났다. 3. 미숙 분만아의 미숙아 모유 및 미숙아 분유 혼합 식이하의 장내 균총을 균속별로 보면 대체로 Bifidobacterium, Bacteroidaceae, Streptococcus, Megasphaera 그리고 Clostridium의 순으로 나타났다. 4. 미숙 분만아의 정상아용 조제 분유 식이하의 장내 균총을 균속별로 보면 대체로 Bacteroidaceae, Bifidobacterium, Streptococcus, Eubacterium 그리고 Clostridium의 순으로 나타났다. 5. 미숙 분만아의 장내 균총에서 일반적으로 총 균수에서는 유익균이, 균속의 종류에서는 유해균이 우세하였다. 6. 34명의 국내 미숙 분만아의 분변 시료로부터 총 16속(Yeasts 제외)의 균을 분리하여 그 균속을 동정하였다. Due to the uniformity of the diet during early life, the composition of the intestinal microfloras is influenced dibectly by the kinds of nutrients during the first month after birth. Especially, in case of preterm infants, the first month after birth is the most important period for survival through their lifetime, and determination of intestinal microflora for this period is important to estimate their digestive diseases and metabolic disorders. This study made an attempt to classify the major intestinal microflora of Korean preterm infants on various milk feedings during the first month after birth. This results which were obtained are as follows: 1. Dominant genuses on total cell counts in gastrointestinal tracts, ranked from highest to lowest, from preterm infants fed preterm-formula-milk were Bifidobacterium, Bacteroidaceae, Clostridium, Eubacterium and Enterobacteriaceae. 2. Dominant genuses on total cell counts in gastrointestinal tracts, ranked from highest to lowest, from preterm infants fed preterm-formula-milk were Bifidobacterium, Enterobacteriaceae, Eubacterium, Bacteroidaceae and Clostridium. 3. Dominant genuses on total cell counts in gastrointestinal tracts, ranked from highest to lowest, from preterm infants fed mixture feeding(preterm-formula-milk and preterm-formula-milk) were Bifidobacterium, Bacteroidaceae, Streptococcus, Megasphaera and Clostridium. 4. Dominant genuses on total cell counts in gastrointestinal tracts, ranked from highest to lowest, from preterm infants fed term-formula-milk were Bacteroidaceae, Bifidobacterium, Streptococcus, Eubacterium, and Clostridium. 5. Dominant microflora on total cell counts in gastrointestinal tracts of preterm infants were lactic bacteria, and septic and pathogenic microflora were predominantly over kinds of species in the preterm infants guts. 6. Sixteen genuses(except on Yeast) were isolated and identified from fecal samples of 34 preterm infants in this experiment.
만성 B 형 간염에서 HBsAg 및 HBcAg 의 간세포 내 발현양상과 병리조직학적 소견과의 상관관계
박경식,안성훈,김상표,황재석,허정욱,조광범,권두영,박승국,손정호 대한간학회 2001 Clinical and Molecular Hepatology(대한간학회지) Vol.7 No.4
Background / Aims : The purpose of this study was to assess the correlation between histologic activity and fibrosis and the distribution of intrahepatic hepatitis B core antigen(HBcAg) and surface antigen(HBcAg ) inpatients with chronic hepatitis B . Methods : 141 patients(M:F=141:27) with biopsy-proven chronic hepatitis B ,abnormal liver function, and a positive HBV viral marker(serum HBeAg , serum HBV DNA) were enrolled. Results : HBcAg was expressed in 96 of 141 patoents(68.1%), n HBcAg in 23(16.3%), c HBcAg in 58(41.25), and n-c HBcAg in 15(10.6%). In the cases of HBsAg, 114 of 141 patients(80.9%) were expressed as c HBsAg, 2(1.4%) as m HBsAg, and 16(11,3%) as m-c HBsAg. The presence of intrahepatic HBcAg and HBsAg according to gudat's calssification was not correlated with activity and fibrosis. But the groups with nuckear expression of HBcAg revealed less inflammatory activity (grade, p=0.003), and less fibrotic stage(p=0.002) than with cytoplasmic or no expression of HBcAg. HBsAg was not. Conclusion : These observations suggest that inflammatory activity and fibrosis of chronic hepatitis B are related to the presence of HBcAg in hepatocytes and the expression of HBcAg. This is a very important finding in hepatocytolysis.
고급한식당 서비스 품질이 고객만족 및재방문 의도에 미치는 영향
박경식,우성근,최성기 한국외식경영학회 2011 외식경영연구 Vol.14 No.5
The objective of this study was to examine the relationships among service quality and customer satisfaction and revisit intention of deluxe Korean restaurant customers. In order to achieve the research purpose, the data was collected from 300 customers and analyzed using SPSS. The exploratory factor analyses identified five underlying dimensions of service quality; tangible, reliable, responsive, assurance, and empathy. Structural equation modeling was adopted to examine the relationships among those variables. The results showed that all the five service quality dimensions were related to customer satisfaction, and also customer satisfaction was related to revisit intention. Among other service quality factors, especially reliable factor was highly related to customer satisfaction. And the managerial implications of these results for service quality of deluxe Korean restaurant customers were discussed.
박경식,김석원,민혜숙,한원식,노동영,박성회,윤여규,오승근,최국진 대한외과학회 2003 Annals of Surgical Treatment and Research(ASRT) Vol.65 No.6
The Hyalinizing trabecular adenoma of the thyroid is a uncommon benign neoplasm which is characterized by trabecular growth pattern with hyaline stroma of the basal membrane type. It is often misdiagnosed as papillary carcinoma due to its peculiar cytologic and histologic features such as, nuclear grooving and papillary structures, or as medullary carcinoma due to the hyalinized stroma resembling amyloid. Special stains and immunohistochemical studies are required to make a definite diagnosis. A 34-year old woman was admitted suffering from a left neck mass. Computed tomography showed a 2 cm-sized mass in the left thyroid. Fine needle aspiration cytology suggested papillary carcinoma. Intraoperative frozen section suggested medullary carcinoma, and H&E staining suggested medullary carcinoma. However according to immunohistochemistry which revealed calcitonin negative, the tumor was reviewed and finally diagnosed as hyaline trabecular adenoma. The hyalinizing trabecular adenoma, although uncommon, is certainly worth consideration in order to avoid being misinterpreted as carcinoma on the basis of individual cytologic and histologic features. (J Korean Surg Soc 2003;65:572-575)
Staphylococcus aureus 의 sublethal heating 후 NaCl 농도에 따른 회복 정도 비교
박경식,김민주,정혜진,김근성 한국식품위생안전성학회 2009 한국식품위생안전성학회지 Vol.24 No.4
The viability of Staphylococcus aureus, a significant cause of food poisoning in Korea, on TSA plates was determined after sublethal heating treatments and NaCl treatments. In addition, recovery levels of sublethally injured cells on TSA plates containing different concentrations of NaCl (TSAS) were investigated. The viability decreased significantly with increasing degree of sublethal heating treatments, but increases in NaCl treatment concentrations from 0 to 6% had little effect on the viability. After being sublethally treated at 55oC for 30 min, bacterial populations were reduced by 7.91, 7.97 and 7.99 log CFU/mL on 2, 4 and 6% TSAS, respectively. After being sublethally treated at 60oC for 30 min, bacterial populations were reduced by 6.46, 6.47 and 6.48 log CFU/mL on 2, 4 and 6% TSAS, respectively. Decimal reduction times (D-value) decreased with increasing NaCl treatment concentrations after sublethal heating at 55 and 60oC. These data imply that the S. aureus cells sublethally injured by insufficient heating processes had a lower recovery rate with increasing NaCl concentrations in the recovery media.