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- 저자 : 문순화 ( Sung Hwa Moon ) (검색결과 3 건)
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박효선 ( Hyo Sun Park ),이효상 ( Hyo Sang Lee ),나기복 ( Ki Bok Na ),이관복 ( Kwan Bok Lee ),강수정 ( Su Jung Kang ),문순화 ( Sun Hwa Moon ) 한국동물위생학회 2006 한국동물위생학회지 (KOJVS) Vol.29 No.1
Porcine circovirus (PCV) is a small, nonenveloped virus that contains a single-stranded circular DNA genome of about 1.76kb and belongs to the family circoviridae. The PCV-2 has been incriminated as the cause of post-weaning multisystemic wasting syndrome(PMWS), an emerging disease in pigs. In the present study, a PCR assay was applied to detect PCV-2 in tissue samples. The presence of PCV-2 antigen in the porcine tissues was confirmed by indirect immunofluorescence(IIF) with PCV-2 specific monoclonal antibodies. And then DNA extracted from PCV-2 positive tissues was used as a template. One oligonucleotide primer suitable for PCR was selected from a published PCV-2 sequence(Genbank). Amplified PCR product was detected the same fragment lengths of 416bp as a control. Based on these results, it was suggested that the PCR is a simple and sensitive method for support diagnostic purposes.
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공신국 ( Shin Koog Kong ),이건택 ( Gun Taek Lee ),이관복 ( Kwan Bok Lee ),홍준표 ( Jun Pyo Hong ),강수정 ( Soo Jeong Kang ),문순화 ( Sung Hwa Moon ) 한국동물위생학회 2003 한국동물위생학회지 (KOJVS) Vol.26 No.3
The purpose of this study was sero-epidemiological survey of porcine reproductive and respiratory syndrom(PRRS) in Dangjin area. 411 samples from 26 pig farms were analyzed by enzyme linked immunosorbant assay (ELISA). The data indicate that 66% of the pigs and 92% of the farms showed sero-positives to the PRRS virus. Sows showed 58% of sero-positive rate and fattening pigs showed 85% of sero-positive rate. The rate of sero-positive in boars was 63%. No significant regional differences were detected in sero-epidemiological survey.
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김지현 ( Ji Hyun Kim ),권혁상 ( Hyuk Sang Kwon ),박용문 ( Yong Moon Park ),임선영 ( Sun Young Lim ),이진희 ( Jin Hee Lee ),이승환 ( Seung Hwan Lee ),임동준 ( Dong Joon Lim ),홍순화 ( Soon Hwa Hong ),조재형 ( Jae Hyoung Cho ),김성 대한내과학회 2007 대한내과학회지 Vol.73 No.6
Background: To investigate the best surrogate marker for insulin resistance in the non-diabetic middle-aged population in Korea. Methods: This study was performed from February to April 2003-2005 in adults over 40 years of age living in Chungju City, South Korea, selected by stratified random cluster sampling. We analyzed the data from a total 6,149 non-diabetic subjects that completed a survey consisting of anthropometric measurement and blood chemistry. We defined the highest quartile of the homeostasis model for insulin resistance (HOMA-IR) as the insulin resistant group in our study population. We also analyzed the correlation of various anthropometric (body mass index, waist circumference, waist to hip ratio, waist to height ratio) and biochemical parameters (total cholesterol to HDL cholesterol ratio, non-HDL cholesterol level, triglycerides to HDL cholesterol ratio and level of triglycerides) with insulin resistance using simple and multiple regression analysis for detecting the insulin resistance group. Results: By simple regression analysis, among the anthropometric parameters including the body mass index, waist circumference, waist to hip ratio, waist to height ratio, and the biochemical parameters, including the total cholesterol to HDL cholesterol ratio, non-HDL cholesterol level, triglyceride to HDL cholesterol ratio and triglycerides level, the body mass index was the best surrogate marker for insulin resistance (95% CI 1.215-1.262). The cut-off value of the body mass index was 24.6 kg/m2 (male; 24.7, female; 24.6 kg/m2), with a sensitivity of 62.6% and specificity of 66.9%. Multiple logistic regression analysis for insulin resistance also gave the same results. Furthermore, the cut-off value of the body mass index for the metabolic syndrome as defined by NCEP-ATP III was also 24.1 kg/m2 (male; 24.0, female; 24.2 kg/m2). Conclusions: Our study results suggest that the body mass index was the best surrogate marker for insulin resistance of a non-diabetic population and its cut-off value was approximately 24 kg/m2. (Korean J Med 73:611-617, 2007)
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