Atorvastatin으로 유도된 근위축 세포모델에서 상황-오미자박 고상발효물 열수추출물의 보호효과

김영숙,황수진,박광일,임종민,천다미,정유진,전병엽,곽경태,오태우,Kim, Young-Suk,Hwang, Su-Jin,Park, Kwang-Il,Lim, Jong-Min,Cheon, Da-Mi,Jung, Yu Jin,Jeon, Byeong Yeob,Kwak, Kyeung Tae,Oh, Tae Woo 대한한의학방제학회 2021 大韓韓醫學方劑學會誌 Vol.29 No.4

Objectives : This study is to effect of improving muscle atrophy through water extract on the solid-phase fermentation extraction with Phellinus linteus of discarded Schisandra chinensis in an atorvastatin-induced atrophy C2C12 cell. Methods : C2C12 myoblast were differentiated into myotube by 2% horse serum medium for 6 days, and then treated solid-phase fermentation(S-P) extract at different concentrations for 24h. To investigate the effect of S-P extract on the induction of muscle atrophy and expression of atrophy-related genes and apoptosis in differentiated C2C12 myotubes using a GSH, ROS, real-time PCR, western blots analysis. Results : As a result of treatment with atorvastatin at concentrations of 5, 10, and 20 uM on the 6th day of differentiation in C2C12 myotube cells, it was confirmed that the cell morphology was damaged in a concentration-dependent manner, and the length and thickness of the myotube also decreased in a concentration-dependent manner. Treatment with S-P extract (50, 100 and 200 ㎍/㎖) increased of GSH and inhibited ROS in the atorvastatin-induced muscle atrophy cell model at a concentration that did not induce toxicity. In addition, it was confirmed that it has an effect on muscle reduction by inhibiting apoptosis of muscle cells as well as being involved in protein production and degradation of muscle cells. Conclusions : Atorvastatin-induced atrophy C2C12 cell, S-P extract activates related to differentiation/generation and proteolysis, and inhibits cell death of atrophy in C2C12 cell. Based on this, it is necessary to prove its effectiveness through animal models and human application test, but it is considered to be discarded Schisandra chinensis can present the potential for development as a recycling industrial material.

부산지역 방문간호사업 실태에 관한 연구

김영숙,박정란,박형숙,이윤미,Kim, Young-Suk,Park, Jung-Ran,Park, Hyoung-Sook,Lee, Yun-Mi 한국가정간호학회 2004 가정간호학회지 Vol.11 No.1

Purpose: The purpose of this research is to give basic data about a way of connection to individual centers and vitalization of visiting nursing program on Busan. Method: The research is done with survey for eight hospitals. sixteen public heath centers, forty-six social welfare centers to be practised visiting nursing program on Busan for actual condition of that. Results: 1. The average nursing career is below 5-10 years. But visiting nursing career is below 3 years(70%) in hospital. public, public heath center, and heath center. 2. Hospitals coverage of visiting nursing service is city as a whole. Whereas public heath center and social welfare center covered some local area. 3. Client of visiting nursing service possess in order of alone lived elderly, person in uncomplete movement, a disabled person, and a chronic disease person. 4. The main service in visiting is patient assessment, basic nursing activity, and treatment nursing activity with medication care, B.P check, dressing, bedsore care, catheter care and exchange, fluid therapy. Particularly, the hospital runs parallel to basic care and treat care in 100%. The social service center has 65.0% in a patient assessment and basic nursing activity. 5. The concern about services connecting with other center is very high. Conclusion: Actual conditions of visiting nursing program on Busan, which is presented in this study. The results of this study will become the pillar of visiting nursing program planning and application.

간호대학생의 행복지수 영향요인

김영숙(Young Suk Kim),한미영(Mi Young Han) 한국간호행정학회 2015 간호행정학회지 Vol.21 No.5

The purposes of this study were to identify the effects of social support, resilience, stress and satisfaction in major on the happiness index of nursing students. Methods: Data were collected from March 16 to April 10, 2015 through a self-report questionnaire survey. Participants were 205 students in three different nursing colleges located in Busan and Yangsan. Measured variables were social support, resilience, stress, satisfaction in major and Happiness index. Results: Social support, resilience, satisfaction in major, and personal relationships had significant positive effects on the happiness index, while stress had a negative effect on the happiness index. Explained variance for the happiness index was 46% and social support was the most significant factor in the happiness index of nursing students. Conclusion: The results from this study suggest that resilience, social support, stress, satisfaction in major, and personal relationships should be considered as the main influential factors when developing intervention strategies to increase of the happiness index of nursing students.

학습자의 모어를 고려한 일본어 문법교육에 관한 고찰 -「で」의 문법지도와 번역전략의 관계를 중심으로-

김영숙 ( Young Suk Kim ) 한국일어교육학회 2009 일본어교육연구 Vol.17 No.-

井上(2005)에서는 학습자의 모어(母語)를 배려한 일본어교육문법이 필요하다고 주장하고 있다. 여기서 학습자의 母語를 배려한다는 것은 학습자의 모어의 관점에서 생각했을 때 학습자가 이해하기 쉬운 일본어문법을 제공하는 것을 말하는데, 그 구체적인 내용 중 한가지로, 일본어와 유사한 언어체계를 갖는 한국어 모어 학습자에게는, 초급 학습항목의 경우, 문법요소라 할지라도 어휘요소로서 지도한다는 것이다. 예를 들어, 「で」는 격조사로서 다양한 용법을 갖고 있으나 초급과정에서는 한국어의 「에서(eseo)」「로(lo)」와 대응관계를 중심으로 지도한다는 것이다. 이러한 지도법은 한국어의 관점에서 일본어를 이해한다는 점에서 학습자의 모어를 일본어학습에 적극적으로 활용할 수 있는 장점이 있고, 실제로 한국어모어화자를 대상으로 한 초급 교과서에서도 이와 같은 설명이 이루어지고 있다. 그러나 다른 한편으로, 한국어 「로(lo)」의 용법이 일본어의 「で」와 완전히 일치하는 것은 아니기 때문에, 「で」와「로(lo)」의 대응관계에만 의존한 문법지도의 문제도 있을 것이 예상된다. 이 논문에서는 이러한 문제의식에서 출발하여, 위와 같은 「で」의 문법지도가 한국어모어학습자의 번역전략에 미치는 영향을 조사했다. 다양한 수준의 일본어 학습자 97명을 대상으로 한국어를 일본어로 번역하는 과제를 시행한 결과, 많은 학습자들이 한국어文이 나타내는 의미나 「로(lo)」의 기능이 아닌, 「로(lo)」의 형태를 「で」로 번역하는 것을 알 수 있었다. 또한, 학습자들은 수업 등의 의식적인 학습이나 의식하지 않는 사이에 이루어지는 학습과정을 통해서 「で」와「로(lo)」의 대응관계를 습득하고 있었으며 번역할 때에는 이러한 지식을 이용하는 것을 알 수 있었다. 井上(2005)では學習者の母語を考慮した日本語敎育文法の必要性について述べられているが、具體的に、日本語と類似した言語體系をもつ韓國語話者の場合、初級の學習項目は文法形式であっても語彙項目として扱うという內容が示されている。このような文法敎育の觀點から韓國語話者を對象とした初級敎科書の「で」の文法說明に注目すると、實際、「で」に關しては「에서(esyo)」「로(lo)」との對應關係に基づいた說明が多く、語彙項目として扱われる傾向が見られる。このような文法指導は學習者の母語を文法敎育に生かすというメリットもあるが、しかし、他方で、韓國語の「로(lo)」の用法は必ずしも「で」のそれと一致するわけではなく、「で」と「로(lo)」の關係を語彙的な關係として捉えた學習者の誤りが予想される。本稿では、このような問題に著目して「で」の文法指導が韓國語話者の飜譯に及ぼす影響を調べた。樣樣なレベルの韓國語話者の學習者97人の飜譯ストラテジ―を調べた結果、多くの學習者が韓國語の「로(lo)」を「で」に飜譯するという形態ストラテジ―を用いることが分かった。なお、學習者は授業などの意識的な學習、あるいは意識しない學習プロセスを通じて「で」と「로(lo)」の形態を關連づけていることが分かった。

고신대학교 간호대학생의 선교소명의식과 선교훈련 경험 현황 조사

김영숙(Kim Young Suk) 고신대학교 전인간호과학연구소 2016 전인간호과학학술지 Vol.9 No.-

Purpose : The purpose of this study is to identify the awareness of the calling of mission and mission training experiences of nursing students in Kosin University. Method : Data were collected from December 1 to 14, 2015. participants were 402 nursing students those who agreed to be part of the research, among entire nursing students in Kosin University. Result : Those students who received calling of mission were 18.2% and among these students those who found it while attending to university were 50%, and those who are interested in were 63.6%. The percentage of students those who received domestic mission training were about 40%, and those who have experienced overseas short term mission training were 30.1%. The programs that affected content of calling of mission were lectures about nursing and mission, chapel, overseas short term mission training, extracurricular activities, spiritual nursing practice, and the missionary’s testimony. Conclusion : The results from this study suggest that to develop the nursing mission, there is a need to develop specific programs for awareness of the calling of mission of nursing and nursing mission volunteers.

항암성과 향미가 개선된 재래식 버섯균사체메주의 제조

김영숙(Young-Suk Kim),박철우(Cherl-Woo Park),김석종(Seck-Jong Kim),박숙자(Sook-Jahr Park),류충호(Chung-Ho Ryu),조현종(Hyun-Jong Cho),김정옥(Jeong-Ok Kim),임동길(Dong-Kil Lim),하영래(Yeong-Lae Ha) 한국식품영양과학회 2002 한국식품영양과학회지 Vol.31 No.6

항암성과 향미가 개선된 기능성 재래식 버섯균사체메주는 버섯균을 액체배양하여 재래식메주의 각 면에 5개씩 만든 구멍(1×3 cm)에 버섯균배양액을 메주 무게의 10%를 접종한 후 25℃에서 4주간 배양하여 제조하였다. 제조한 버섯균사체 메주 중 상황, 영지, 또는 신령버섯균사체메주가 항암성과 향미완화능이 우수하였다. Mushroom mycelia-cultured traditional meju (MTM) was prepared by inoculating 10% submerged-liquid culture of mushroom strains to five holes (1×3 cm) per side of the traditionally-fermented meju (10×10×10 cm), followed by incubating additional 4 weeks at 25℃. Mushroom strains used were Neutari (Pleurotus ostreatus, PO), Yeongji (Ganoderma lucidum, GL), Synryeong (Agaricus blazei, AB), Ypsae (Grifola frondosa, GF), Pyogo (Lentinus edodes, PE), Dongchunghacho (Paecilomyces japonicus, PJ) and Sanghwang (Phellinus linteus, PL). All MTMs showed an enhanced anticarcinogenicity against S-180 cell-induced mouse ascites cancer, antimutagenicity against aflatoxin B₁ (AFB₁) and 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), and sensory qualities, relative to control meju. Such positive effects of MTM prepared with Sanghwang, Yeongji, or Synryeong were superior to those of MTM with Ypsae, Pyogo, Dongchunghacho, or Neutari.

남자 스피드 스케이팅 500 m 후반부 직선 구간 스트로크의 운동역학적 분석

김영숙(Kim, Young-Suk),홍성홍(Hong, Seong-Hong),류재균(Ryu, Jae-Kyun) 한국체육과학회 2018 한국체육과학회지 Vol.27 No.1

The purpose of this study was to investigate the consistency, work per stroke and power of the gliding and push-off motion for speed skating 400-500 m section. The study included fourteen male 500 m speed skaters (mean height, 1.80 ± 0.03 m; mean weight, 76.1 ± 4.38 kg; record, 35.58 ± 2.73 sec)were divided three groups by record(A〈36.00 sec, 36.00 sec ≤ B ≤ 36.50 sec, C〉36.50 sec). Data were collected four strokes from middle of 400-500 m section and recorded using six digital SONY FDR-AXP35 video cameras (SONY, Japan) operating at a sampling frequency of 60 fields/sec and shutter speed of 1/500 sec. For each film frame, the joint positions were digitized using the KWON3D motion analyzer. Position data were filtered with low-pass Butterworth 4th order at the cut-off frequency of 7.4 Hz. The results of the study showed that the stroke time, the gliding distance, the stroke width and the amount of work per stroke was high value and the stroke frequency was low. On the contrary, the stroke time, the stroke distance, the stroke width and the amount of work per stroke is low value, and the stroke frequency is increased. This study"s findings indicate that the skaters need to improve their physical strength to perform a consistent and symmetrical stroke. To increase the amount of work per stroke, the stroke distance should be increased while reducing stroke time. Stroke frequency should be increased to increase power. In order to increase the frequency, it is necessary to adjust the stroke width. Stroke frequency and stroke width are important to improving performance.

인공 초기우식병소에 대한 나노크기 탄산인회석의 재광화 효과

김영숙 ( Young Sook Kim ),민지현 ( Ji Hyun Min ),김영석 ( Young Seok Kim ),홍석진 ( Suk Jin Hong ),권호근 ( Ho Keun Kwon ),김백일 ( Baek Il Kim ) 대한예방치과·구강보건학회 2009 大韓口腔保健學會誌 Vol.33 No.1

공적연금 수급과 자기효능감 및 삶의 만족도와의 상관관계 연구

김영숙(Young-Suk Kim),양영애(Yeong-Ae Yang) 대한고령친화산업학회 2023 대한고령친화산업학회지 Vol.15 No.2

연구목적 본 연구는 공적연금 수급이 노인들의 자기효능감과 삶의 만족도에 미치는 영향을 확인하여 공적연금의 중요성을 제고하고, 정부의 연금개혁에 시사점을 제공하고자 한다. 연구방법 2023년 9월 1일부터 2023년 10월 9일까지 도시와 농촌지역에 거주하는 만 65세 이상 노인을 대상으로 설문조사를 한 후 신뢰도 분석, 기술통계 분석, 집단 간 차이 분석, 상관관계 분석, 인구통계학적특성에 따른 빈도분석 등을 통해 가설검증을 진행하였다. 연구결과 공적연금 수급 여부와 공적연금의 종류 및 수급액, 그리고 도시와 농촌지역 거주지에 따라서도 자기효능감과 삶의 만족도에 유의한 차이가 나타났다. 공적연금을 받는 노인들의 받지 않는 노인들에 비하여 자기효능감과 삶의 만족도가 높게 나타났으며, 공적연금의 종류 및 수급액에 따라서도 사학연금 및 군인연금 등 수급액이 많은 연금이 그렇지 않은 연금수급자에 비해 자기효능감과 삶의 만족도가 높게 나타났다. 그리고 도시와 농촌지역 거주에 따라서는 도시거주자의 자기효능감 및 삶의 만족도가 높게 나타났다. 결론 우리나라는 2025년도에 초고령사회에 진입할 것으로 예상되나 노인빈곤률은 OECD 국가 중 높은 수준이다. 이러한 현실에서 노인의 안정된 삶을 유지시켜 줄 수 있는 것은 공적연금이 가장 유효한 수단 중의 하나일 것이다. 정부는 공적연금의 재정은 언젠가 고갈될 수밖에 없는 상황에서 공적연금을 적정수준으로 계속 유지시켜 나가기 위한 정책 수립이 필요하고, 각 개인은 공적연금 가입을 통해 노후생활을 보장하며 나아가 사적연금 및 기타 소득보장 대책을 강구해야 할 것으로 사료된다. Objective : Such research confirms the effect of public pension benefits on self-competence and life satisfaction of the elderly lt aims to enhance the importance of public pensions and provide implications for the government’s pension reform. Methods : After surveying the elderly aged 65 or older living in urban and rural areas, hypothesis testing was conducted through reliability analysis, descriptive statistics analysis,.group difference analysis, correlation analysis, and frequency analysis according to demographic characteristics. Results : There were significant differences in self-efficacy and life satisfaction depending on whether or not to receive public pensions, the type and amount of public pensions, and urban and rural areas. Elderly people receiving public pensions had higher self-efficacy and life satisfaction than those who did not receive them, and pensions with high benefits such as military tuition and faculty pensions had higher self-efficacy and life satisfaction than those who did not. In addition, residents in urban areas showed high self-efficacy and life satisfaction according to their residence in urban and rural areas. Conclusion : Korea is expected to enter an ultra-aged society in 2025, but the elderly poverty rate is the highest among OECD countries. In this reality, public pensions are one of the most effective means of maintaining the lives of the elderly. The government needs to establish policies to maintain the public pension at an appropriate level at a time when the finances of the national pension, civil service pension, private school pension, and military pension are inevitably depleted, and each individual should secure his or her retirement life by joining the public pension and further devise private pension and other income security measures.

초등학생의 학업성취도에 대한 학업낙관성 잠재집단 유형과 인지, 동기, 정서 변인들의 예측효과 분석

김영숙 ( Kim Young-suk ),조한익 ( Cho Han-ik ) 한국아동교육학회 2017 아동교육 Vol.26 No.2

본 연구는 초등학생의 학업성취도에 대한 학업낙관성 잠재집단 유형과 인지, 동기 및 정서 변인들이 학업낙관성 잠재집단에 어떠한 영향을 미치는가를 분석하는데 목적이 있다. 연구대상은 9개 초등학교 5학년 학생들로 남학생은 403명, 여학생은 331명, 총 734명이다. 학업낙관성 잠재집단 유형을 살펴보기 위한 측정도구는 학업낙관성, 국어, 수학교과 성적이며, 예측요인들의 영향력을 분석하기 위한 측정도구는 인지전략, 메타인지전략, 성취목표지향성, 자기결정성, 성취정서 등이다. 학생용 설문지와 교사용 설문지는 2013학년도 11월에 배부하여 12월 말에 수거하였으며 학업성취도 결과는 C도교육청의 교육연구정보원에서 11월말에 실시한 도학력평가의 국어, 수학 교과 점수를 사용하였다. 연구 결과 학업낙관성 잠재집단 유형은 3개가 적합한 것으로 나타나 잠재집단 1은 교사신뢰와 가족의 학업지지를 바탕으로 한 학업효능감형으로, 잠재집단 2는 가족의 학업지지를 바탕으로 한 학업효능감형으로, 잠재집단 3은 낮은 학업효능감형으로 명명하였다. 이 세 집단에서 학업성취도가 가장 높은 집단은 잠재집단 1이며, 잠재집단 2, 잠재집단 3의 순서로 학업성취도가 낮게 나타났다. 잠재집단 1에서 학업성취도에 미치는 요인들로는 숙달목표, 수행접근, 수행회피, 자기결정성, 즐거움, 지루함, 불안감으로 나타났다. 잠재집단 2에서 학업성취도에 미치는 요인들로는 자기결정성, 즐거움으로 나타났다. 잠재집단 3에서 학업성취도에 미치는 요인들은 나타나지 않았다. 잠재집단 3을 참조변인으로 하여 다항로지스틱 회귀분석을 한 결과 잠재집단 1과 잠재집단 2는 잠재집단 3에 비해서 자기결정성이 높고 즐거움과 불안감 정서가 낮게 나타났다. 본 연구는 학업성취도에 대한 학업낙관성 잠재집단 유형을 살펴보고 이러한 잠재집단에 영향을 미치는 인지, 동기, 정서 변인들의 예측요인을 확인함으로써 각 집단 별로 차별적인 교육적 처치가 필요함을 제시하였다는데 의의가 있다. The purpose of the study is to analyze latent classes in relation to the impact of academic optimism on academic achievement in elementary school students, and to investigate the effects of cognition, motivation, and emotion variables on mixed-regression latent groups. The subjects were 403 male and 331 female students. The instruments used in the study were academic optimism, cognitive strategy, meta-cognitive strategy, achievement goal orientation, self-determination, and achievement emotions. A mixed regression analysis showed that three latent groups were appropriate. Latent group 1 was named as academic efficacy type based on teacher trust and family academic support, Group 2 was named as academic efficacy based on family academic support, while latent group 3 was named as low academic efficacy. Performance approach, performance avoidance, self-determination, pleasure, boredom, and anxiety were the factors that affected academic achievement in latent group 1. Self-determination and pleasure were the factors that influenced academic achievement in latent group 2. There were no factors affecting academic achievement in latent group 3. Multinomial logistic analysis using latent group 3 as a reference revealed that latent group 1 and 2 had higher self-determination and lower pleasure than latent group 3. Based on these studies, researchers discussed the relevance of previous studies, their significance and limitations.