치주치료 후 구강 내 Volatile Sulfur Compounds(VSC)의 변화

김성현,채경준,정의원,김창성,최성호,조규성,채중규,김종관,방은경,Kim, Sung-Hyun,Chae, Gyeong-Jun,Jung, Ui-Won,Kim, Chang-Sung,Choi, Seong-Ho,Cho, Kyoo-Sung,Chai, Jung-Kyu,Kim, Chong-Kwan,Bang, Eun-Gyeong 대한치주과학회 2006 Journal of Periodontal & Implant Science Vol.36 No.3

Oral malodor may cause a significant social or psychological handicap to those suffering from it. Oral malodor has been correlated with the concentration of volatile sulfur compounds (VSC) produced in the oral cavity. Specific bacteria identified in the production of VSC have been reported and many of these bacteria are commonly suspected periodontal pathogens. The aim of this study was to estimate the change of the VSC concentration after periodontal treatment, Twenty subjects with probing depth $(PD)\;{\geq}5mm$ (experimental group) and 20 subjects with PD<5mm (control group) participated. VSC concentration measurement was made with gas chromatography. VSC concentration was measured at pre-treatment, 2 weeks after scaling and 1 month after periodontal treatment(root planning and flap operation). Maximum probing depth and bleeding on probing(BOP) were also examed at pretreatment and 1 month after periodontal treatment, The conclusions were as follow: 1. In the experimental group VSC concentration and CH3SH/H2S ratio were higher than control group. (p<0.05) 2. Both VSC concentration and CH3SH/H2S ratio showed decrease after periodontal treatment, But only CH3SH/H2S ratio after 1 month periodontal treatment was statistically significantly different from pre-treatment. (p<0.05) 3. CH3SH/H2S ratio tended to be on increase according to maximum probing depth and bleeding on probing. Periodontal disease could be a factor that caused oral malodor and oral malodor could be decreased after periodontal treatment.

순천만 갈대근권 토양으로부터 얻은 PAH 분해세균의 특성 분석

김성현,강성미,오계현,김승일,윤병준,강형일,Kim Sung-Hyun,Kang Sung-Mi,Oh Kye-Heon,Kim Seung-Il,Yoon Byoung-Jun,Kahng Hyung-Yeel 한국미생물학회 2005 미생물학회지 Vol.41 No.3

This study was accomplished in order to collect fundamental data on microbial roles in recycling process of reed rhizosphere. Sunchon bay, which is considered as one of the marsh and mud environments severely affected by human activities such agriculture and fisheries, was selected as a model place. In our initial efforts, two bacterial consortia were obtained by enrichment culture using PAH mixtures containing anthracene, naphthalene, phenanthrene and pyrene as the sources of carbon and energy, and four pure bacteria capable of rapid degradation of PAH were isolated from them. Four strains designated as SCB1, SCB2, SCB6, and SCB7 revealed by morphological, physiological and molecular analyses were identified as Burkholderia anthina, Alcaligenes sp., Achromobacter xylosoxidans., and Pseudomonas putida, respectively with over $99{\%}$ confidence. Notably, Burkholderia anthina SCB1 and Alcaligenes sp. SCB2 were found to utilize anthracene and pyrene more quickly than naphthalene and phenanthrene, whereas Achromobacter xylosoxidans SCB6 and Pseudomonas putida SCB7 exhibited similar growth and degradation patterns except for pyrene. These facts suggest that the rhizosphere microorganisms capable of PAH degradation might be used to clean up the contamination sites with polycyclic aromatic hydrocarbons. 본 연구는 농업과 어업, 그리고 생태체험과 같은 인간들의 활동으로 인하여 상당히 영향을 받는 갯벌환경 중의 하나인 순천만을 모델장소로 갈대의 환경정화 기능에 있어 근권에 분포하는 미생물의 역할에 대한 기초 자료를 얻고자 수행하였다. 우선, 순천만의 갈대근권 토양을 시료로하고 anthracene, naphthalene, phenanthrene, pyrene 등이 첨가된 다환성 방향족 화합물(polycyclic aromatic hydrocarbons; PAH)을 탄소원 및 에너지원으로 하는 농화 배양을 통하여 두 개의 consortium을 획득하였다. 두 consortium으로부터 순수 분리된 우수한 PAH분해능을 갖는 4개의 균주(SCB1, SCB2, SCB6,그리고 SCB7)를 형태 및 생리학적 특성과 16S rRNA유전자서열을 기초로 분석한 결과 각 균주는 $99{\%}$ 이상의 신뢰도로 Burkholderia sp., Aicaligenes sp., Achromobacter sp., and Pseudomonas sp.로 동정되었다. 주목할 만한 점은 Burkholderia sp. SCB1과 Alcaligenes sp. SCB2는 naphthalene이나 phenanthrene보다 훨씬 안정되어 있는 구조의 anthracene이나 pyrene에서 더 빠른 성장률과 기질 분해율을 나타내는 것으로 밝혀졌다. 반면,Achromobacter sp. SCB6와 Pseudomonas sp. SCB7은 pyrene을 제외한 다른 시험기질에 대하여 유사한 성장 및 분해패턴을 나타내었다. 이러한 결과는 주요한 염습지 식물중의 하나인 갈대의 근권에서 살아가는 이들 PAH 분해 균주들이 PAH와 같은 물질로 오염된 근권 환경의 정화작용에 중요한 역할을 할 수 있음을 제시해 주었다.

풀러렌-물 클러스터의 상호작용에 대한 양자 역학적 이론 연구

김성현,신창호,김지선,강소영,김승준,Kim, Sung-Hyun,Shin, Chang-Ho,Kim, Ji-Sun,Kang, So-Yung,Kim, Seung-Joon 대한화학회 2015 대한화학회지 Vol.59 No.1

풀러렌(fullerene)의 내부에 캡슐화될 수 있는 물 분자의 수와 물 분자들이 증가함에 따라 풀러렌의 안정적인 구조에 미치는 영향을 조사하기 위해 밀도 범함수 이론(density functional theory, DFT)을 이용하여 풀러렌-물 클러스터$(H_2O)_n@C_{60}$, (n=1-10)의 구조 변화에 따른 열역학적 안정성 및 결합에너지를 계산하였다. 각각의 구조들에 대해서 여러 이론 수준에서 최적화하였으며 진동주파수를 계산하여 가장 안정한 구조를 조사하고 IR 스펙트럼을 예측하였다. 또한 풀러렌 내의 물 분자 수가 증가함에 따른 수소결합의 세기 변화를 순수한 물 클러스터$(H_2O)_n$, (n=1-6)의 수소결합과 비교 분석하였다. The density functional theory (DFT) calculations on $(H_2O)_n@C_{60}$, (n=1-10) complexes have been performed to elucidate hydrogen interaction between fullerene and water clusters. The optimized geometries, harmonic vibrational frequencies, and binding energies are predicted at various levels of theory. The harmonic vibrational frequencies for the molecules considered in this study show all real numbers implying true minima. We also compare the H-bond interaction between $(H_2O)_n$ and $(H_2O)_n@C_{60}$, (n=1-10) clusters.

증기화 증폭시트를 적용한 전자빔 가공 특성 연구

김성현,정성택,김현정,백승엽,Kim, Seong Hyun,Jung, Sung Taek,Kim, Hyun Jeong,Baek, Seung Yub 한국금형공학회 2018 한국금형공학회지 Vol.12 No.2

Recently, as machine components and products are getting smaller, it is demanded to develop superprecision production technologies multilaterally. Along with the advancement of production technology, people are paying keener attention to the development of eco-friendly technology and efficient processing technology. Particularly, in many industries related to automobiles, shipbuilding, or airplane components, it is demanded to obtain technology to process multiple micro-holes. On account of this trend, micro-hole processing employing high-power electron beams is rising nowadays, and more interest is being shown in it, too. In Korea, however, the process of manufacturing vaporized amplification sheets influencing high-power electron beam processing technology and the processability considerably has not been developed sufficiently yet. Therefore, this study has applied vaporized amplification sheets manufactured to analyze the processability of high-power electron beams and examine necessity for vaporized amplification sheets.

N과 AlN 시트에 다양한 기체(CO_x, NO_x, SO_x)의 흡착에 관한 이론 연구

김성현,김백진,신창호,김승준,Kim, Sung-Hyun,Kim, Baek-Jin,Shin, Chang-Ho,Kim, Seung-Joon 대한화학회 2017 대한화학회지 Vol.61 No.1

본 연구는 그래핀과 유사한 2차원 붕소-질소(BN)와 알루미늄-질소(AlN) 시트에 여러 대기 유해 가스($CO_x$, $NO_x$, $SO_x$)가 흡착될 때의 구조적 특징과 결합에너지를 밀도 범함수 이론(DFT)과 MP2 방법을 사용하여 연구하였다. 분자 구조는 $B3LYP/6-31G^{**}$와 $CAM-B3LYP/6-31G^{**}$이론 수준에서 최적화하고, 진동 주파수를 계산하여 열역학적으로 가장 안정한 분자 구조를 확인하였다. 결합에너지는 $MP2/6-31G^{**}$ 이론 수준에서 한 점(single point) 에너지를 계산하고, 영점 진동에너지(ZPVE)와 바탕집합 중첩에러(BSSE)를 모두 보정하였다. BN 시트에 가스의 흡착은 모두 물리흡착으로 예측되었으며, AlN 시트에 대한 가스 흡착은 $CO_x$나 $NO_x$에 대해서는 물리흡착이 그리고 $SO_x$에 대해서는 화학 흡착이 일어날 것으로 예측되었다. The adsorption of various atmospheric harmful gases ($CO_x$, $NO_x$, $SO_x$) on graphene-like boron nitride(BN) and aluminum nitride(AlN) sheets was theoretically investigated using density functional theory (DFT) and MP2 methods. The structures were fully optimized at the $B3LYP/6-31G^{**}$ and $CAM-B3LYP/6-31G^{**}$ levels of theory and confirmed to be a local minimum by the calculation of the harmonic vibrational frequencies. The MP2 single-point binding energies were computed at the $CAM-B3LYP/6-31G^{**}$ optimized geometries. Also the zero-point vibrational energy (ZPVE) and 50%-basis set superposition error (BSSE) corrections were included. The adsorptions of gases on the BN sheet were predicted to be a physisorption process and the adsorptions of gases on the AlN sheet were predicted to be a physisorption process for $CO_x$ and $NO_x$ but to be a chemisorption process for $SO_x$.

수학적 재능에 대한 Krutetskii의 연구 분석

김성현,한인기,Kim, Sung-Hyun,Han, In-Ki 영남수학회 2011 East Asian mathematical journal Vol.27 No.4

In this study we study Krutetskii and Krutetskii's monograph 'The Psychology of Mathematical Abilities in Schoolchidren' which is published in Russia(in Russian) and USA(in English). We describe Krutetskii's biography briefly, which was not published in Korea. We analyze the methods, procedures, and results which are presented in the Krutetskii' work, and systemize these. Our study will give a overview of Krutetskii' viewpoint about mathematical abilities.

기천(氣喘)에 대(對)한 문헌적(文獻的) 고찰(考察)

김성현,Kim, Sung-Hyun 대한한방내과학회 1992 大韓韓方內科學會誌 Vol.13 No.2

This study has been carried out to investigate the cause, symptom and treatment of Gi-Chun (氣喘) by referring to 32 literatures. The results were obtained as follows; 1. The factor causing Gi-Chun (氣喘) is almost damage of feeling (七情損傷). 2. The symptom of Gi-Chun (氣喘) is as follows. agony, breathing urgent, cold hand and feet, body tired, low appetite 3. The treatment of Gi-Chun (氣喘) is as follows. Sunpaeganggi(宣肺降氣), Jihaepyungchun(止咳平喘), gudam(去痰) 4. The drugs(herb) of Gi-Chun (氣喘) is as follows. Samatang(四磨湯), Sachiltang(四七湯), Sojaganggitang(蘇子降氣湯), Gilgyungjigaktang(桔梗枳殼湯), Gamisachiltang(加味四七湯), Gamisoyosan(加味逍遙散).

키토산 분자량에 따른 Rhodamine 6G-Sodium Dodecyl Sulfate계의 응집효과에 관한 연구

김성현,나재운,오정선,송기동,Kim, Sung Hyun,Nah, Jae Woon,Oh, Jeong Sun,Song, Ki Dong 대한화학회 1998 대한화학회지 Vol.42 No.6

Chitin was extracted from crab shell of Portuns triberculatus and deacethylated to yield chitosan with various molecular weights. The absorption and the fluorescence spectra of Rhodamine 6G(Rh 6G)-sodium dodecyl sulfate(SDS) and Rh 6G-chitosan systems were obtained. From the spectra, we observed that the absorption and the fluorescence intensity of Rh 6G-SDS system decreased when S/D(the concentration of SDS to that of Rh 6G ratio) was below or at 32, while they increased when S/D was above 32. From the suspended solid(SS) removal rate and the transmittance of Rh 6G-SDS-chitosan system, we found that when S/D ratio was 32 its flocculating behaviour was much stronger than Rh 6G-SDS system. As the concentration and the molecular weight of chitosan increased, we also found that S/D range was extended from 32 to 100. With increasing the molecular weight of chitosan, the SS removal rate increased around pH 2~9 but decreased remarkably at pH>12. 산업폐기물인 꽃게의 껍질로부터 chitin을 탈아세틸화시켜 분자량이 서로 다른 chitosan을 제조하였다. Rhodamine 6G(Rh 6G)-sodium dodecyl sulfate(SDS)계 및 Rh 6G-chitosan계들의 흡수 및 형과 spectra를 조사하였고, chitosan의 분자량 및 pH에 따른 Rh 6G-SDS-chitosan계의 응집효과에 대해 조사하였다. Rh 6G-SDS계의 흡광도나 형광세기는 S/D(SDS 농도/Rh 6G 농도)=32 이하에서 감소하다가 그 이상에서 다시 증가하였다. 부유물질(SS) 제거율이나 투광도로부터 S/D=32에서 chitosan을 첨가한 Rh 6G-SDS-chitosan계의 응집 성능이 Rh 6G-SDS계에 비해 훨씬 우수함을 알 수 있었다. 그리고 chitosan의 농도나 분자량이 크면 클수록, S/D 첨가 범위는 32에서 100까지 확대되는 것을 알 수 있었다. 부유물질의 제거율은 chitosan의 분자량이 클수록 pH 2∼9에서 우수한 성능을 가지는 반면, pH 12 이상에서 부유물질의 제거율은 현저히 저하되는 것을 알 수 있었다.

퍼지적분을 이용한 영상품질의 객관적이고 정량적 평가: 팬톰 연구

김성현,서태석,최보영,이형구,Kim, Sung-Hyun,Suh, Tae-Suk,Choe, Bo-Young,Lee, Hyoung-Koo 한국의학물리학회 2008 의학물리 Vol.19 No.4

물리적 평가(physical evaluation)가 영상품질의 객관화와 정량화를 위한 토대를 제공함에도 불구하고, 부정확하고 가변적인 특성을 지닌 주관적 평가(subjective evaluation)가 영상평가에 중요한 역할을 하게 된다. 본 연구에서는 디지털 방사선 영상의 물리적 평가와 주간적 평가의 단점을 상호 보완하고 객관적 정량화를 위한 새로운 방법을 제안하고자 한다. 임상에 사용되고 있는 4대의 디지털 방사선 영상 촬영장치로부터 동일한 임상조건에서 흉부 팬톰 영상을 획득하였다. 물리적 영상평가를 위하여 디지털 흉부 팬톰 내에서 3개의 영역(폐, 심장, 그리고 복부)에 존재하는 CNR (contrast-to-noise ratio)를 측정하였고 분할(segmentation)과 정합(registration)등 다양한 영상처리기술이 적용되었다. 주관적 평가는 5명의 관찰자에 의한 저 대조도 물체의 식별 정도를 점수화 하였다. 두 평가의 특성을 보완 및 결합하고자 퍼지적분 이론이 도입되었다. 4대의 시스템으로부터의 평가결과가 비교되었으며, 물리적 평가와 주관적 평가가 항상 비례하지 않음을 보였다. 물리적 평가에서는 높은 점수를 보였던 시스템이 주관적 평가에서는 상대적으로 낮은 평가를 보였다. 본 연구에서 제안한 퍼지적분에 의한 영상평가의 정량화는 물리적 평가와 주관적 평가를 모두 포함하는 총체적인 평가 방법이며, 다양한 영상품질 평가에 유용할 것이라 사료된다. Physical evaluations provide the basis for an objective and quantitative analysis of the image quality. Nonetheless, there are limitations in using physical evaluations to judge the utility of the image quality if the observer's subjectivity plays a key role despite its imprecise and variable nature. This study proposes a new method for objective and quantitative evaluation of image quality to compensate for the demerits of both physical and subjective image quality and combine the merits of them. The images of chest phantom were acquired from four digital radiography systems on clinic sites. The physical image quality was derived from an image analysis algorithm in terms of the contrast-to-noise ratio (CNR) of the low-contrast objects in three regions (lung, heart, and diaphragm) of a digital chest phantom radiograph. For image analysis, various image processing techniques were used such as segmentation, and registration, etc. The subjective image quality was assessed by the ability of the human observer to detect low-contrast objects. Fuzzy integral was used to integrate them. The findings of this study showed that the physical evaluation did not agree with the subjective evaluation. The system with the better performance in physical measurement showed the worse result in subjective evaluation compared to the other system. The proposed protocol is an integral evaluation method of image quality, which includes the properties of both physical and subjective measurement. It may be used as a useful tool in image evaluation of various modalities.

FR4 PCB면적과 Via-hole이 LED패키지에 미치는 열적 특성 분석

김성현,이세일,양종경,박대희,Kim, Sung-Hyun,Lee, Se-Il,Yang, Jong-Kyung,Park, Dae-Hee 한국전기전자재료학회 2011 전기전자재료학회논문지 Vol.24 No.3

In this study, the heat transfer capability have been improved by using via-holes in FR4 PCB, when the LED lighting is designed to solve the thermal problem. The thermal resistance and junction temperature were measured by changing the dimension of FR4 PCB and size of via hole. As a result, when the dimension was increased initially, the thermal resistance and junction temperature was decreased rapidly, the ones was stabilized after the dimension of 200 $[mm^2]$. Also, the light output was improved up to maximum 17% by formation of via-hole and expansion of dimension in FR4 PCB. Therefore, the thermal resistance and junction temperature could be improved by expansion of PCB dimension and configuration of via-hole ability.