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에이전트 기반 Mobile IP 라우팅 최적화에 관한 연구
김보균 제주한라대학 2002 論文集 Vol.26 No.-
With recent advances in wireless communication technology, mobile computing is an increasingly important area of research. Enabling mobility in IP networks is a significant issue for making use of many portable devices appearing on the Internet. The IP mobility support being standardized in the IETF utilizes tunneling of IP packets from a Home Agent to a Foreign Agent to make the mobility transparent to the higher layer. In this paper, we propose an approach to optimize routing path and avoid triangular routing problem in IP mobility, which a routing table, called Mobile Routing Table(MRT), is designed in each edge router such as Home Agent, Foreign Agent and general router. A packet retransmission scheme is also proposed to reduce the packet loss during handoff. We analyze and compare both the standard Mobile IP and the proposed seamless handoff approach. Finally, the simulation results are presented.
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유두상 갑상선 암에서 p21, p53 및 증식세포 핵항원(PCNA)의 예후인자로서의 유용성
김보균,서성옥 고려대학교 의과대학 1997 고려대 의대 잡지 Vol.34 No.1
There were many studies t o show that p21. p53 and PCNA overexpression were known to be predictive factors for human cancer. The purpose of this study was to evaluate whether these molecular oncogenes were useful as prognostic factors in patient with papillary thyroid carcinoma. Using the monoclonal antibodies MAb Y13-259, PAb 1801 and PClO against each oncogene protein studied, the avidin-biotin peroxidase complex method provided immunohisto-chemical staining of bound oncogene protein for p21-ras, p53 and PCNA, respectively. Analysis were made on paraffin-embedded pathology tissues of 58 patients with papillary thyroid cancer who underwent thyroidectomy in Korea University Anam Hospital from January 1984 to December 1992. Forty-six patients were women (79.3%) and 12 were men (21.7%), with mean age 42.0±19.2 years. Patients were divided into groups based on postoperative tumor recurrence. Eleven patients had recurrence of disease ; 47 remained free of loco-regional or distant metastasis at mean follow-up of 74.3 months(range 36 142 months). The positive rates of p21. p53 and PCNA were 22.2% (13 of 56), 45.6% (26 of 57) and 70.9% (39 of 55) respectively. No significant differences were observed in the age and sex of patients with p21, p53 and PCX4 positive and negative tumors. Using stastical analysis, there was no significant difference in p21, p53 and PCNA stains between recurrent and non-recurrent groups (p>0.05). while AMES score (p=0.042). the tumor size (p=0.005). capsular invasion(p=0.003) and lymph node metastasis(p=0.002) were significantly correlated with tumor recurrence. Conclusion : This study shows that expression of p21, p53, PCNA are not useful as prognostic factors in papillary thyroid cancer.
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Impact of Several Types of Stresses on Short-term Memory and Apoptosis in the Hippocampus of Rats
김보균,Il-Gyu Ko,김성은,김창주,윤지상,백형환,진병관,이충열,백상빈,신말순 대한배뇨장애요실금학회 2013 International Neurourology Journal Vol.17 No.3
Purpose: Stress has a deteriorating effect on hippocampal function. It also contributes to symptom exacerbation in many disease states, including overactive bladder and interstitial cystitis/bladder pain syndrome. We investigated the effects of various types of stresses (restraint, noise, and cold) on short-term memory and apoptosis in relation with corticotropin-releasing factor (CRF) expression. Methods: Rats in the restraint stress group were restrained in a transparent Plexiglas cylinder for 60 minutes twice daily. Rats in the noise stress group were exposed to the 120 dB supersonic machine sound for 60 minutes twice daily. Rats in the cold stress group were placed in a cold chamber at 4°C for 60 minutes twice daily. Each stress was applied for 10 days. A step-down avoidance test for short-term memory, immunohistochemistry for caspase-3 expression, and western blot analysis for Bax and Bcl-2 expressions were conducted. Results: Latency time was decreased and CRF expression in the hippocampal dentate gyrus and hypothalamic paraventricular nucleus were increased in all of the stress groups. The number of caspase-3-positive cells in the hippocampal dentate gyrus was increased and the expressions of Bax and Bcl2 in the hippocampus were decreased in all of the stress groups. Conclusions: All of the stress groups experienced short-term memory impairment induced by apoptosis in the hippocampus. The present results suggest the possibility that these stresses affecting the impairment of short-term memory may also induce functional lower urinary tract disorders.
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마음챙김과 우울의 관계: 정서인식명확성과 적응적 인지적 정서조절전략의 간접효과
김보균,이민규 한국청소년학회 2019 청소년학연구 Vol.26 No.12
The purpose of this study was to identify the indirect effects of Emotion Clarity and Adaptive Cognitive Emotion Regulation in the relationships between Mindfulness and Depression. The subjects of this study were 275 collegian. The questionnaires used in this study were Mindfulness scales (MS), Korea Depression Scale (KDS), Trait Meta Mood Scale (TMMS) and Korean Cognitive Emotion Regulation Questionnaire (K-CERQ). SPSS 21.0 and AMOS 21.0 were used for data analysis. Date analysis includes descriptive statistics analysis, correlation analysis, reliability analysis, structural equation models analysis. To verify the research model. Structural Equation Modeling(SEM) was used and the results indicated and acceptive goodness of fit indices. also, to identify the indirect effects, Bootstrapping method was used. The results of study were as follows: First, Mindfulness affected Depression. Second, Emotion Clarity affected indirectly between Mindfulness and Adaptive Cognitive Emotion Regulation Strategies. Third, Adaptive cognitive Emotion Regulation Strategies affected indirectly between Emotion Clarity and Depression. Fourth, Sequential indirect effect of Emotion Clarity and Adaptive cognitive Emotion Regulation between Mindfulness and Depression was significant. Finally, Implications and limitations of this study were discussed. In addition, suggestions for future study were presented. 본 연구는 마음챙김이 우울에 미치는 영향에서 정서인식명확성과 적응적 인지적 정서조절전략의 간접효과를 검증하였다. 이를 위해 경남 지역의 대학생 남녀 275명을 대상으로 마음챙김, 우울, 정서인식명확성, 적응적 인지적 정서조절전략에 대한 질문지를 사용하여 설문조사를 실시하였고 무응답이나 이상치가 있는 57명의 자료를 제외한 218명의 자료를 최종 분석에 사용하였다. 상관분석을 통해 측정변인 간의 관계를 검토하였고, 변인 간의 구조적 관계를 살펴보고 간접효과를 검증하기 위하여 구조방정식 모형분석을 실시하였다. 연구결과, 마음챙김이 정서인식명확성과 적응적 인지적 정서조절전략을 순차적으로 경유하여 우울에 영향을 미치는 간접효과가 유의한 것으로 나타났다. 이러한 결과를 바탕으로 의의와 제한점에 대하여 논의하였다.
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