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대체 비상탈출 조건을 고려한 초음속 전투기용 캐노피 작동부 구조해석
김동현,김동만,김영우,양건명,Kim, Dong-Hyun,Kim, Dong-Man,Kim, Young-Woo,Yang, Jian-Ming 한국군사과학기술학회 2007 한국군사과학기술학회지 Vol.10 No.4
In this study, analysis of structural design criteria for the canopy actuating device has been conducted considering the aerodynamic breakaway capabilities of jettisonable canopy system. Unsteady aerodynamic loads for the opened canopy configuration at passively controlled jettision mode were computed using CFD method. The general purpose multi-body finite element code, SAMCEF Mecano, is used in the implemented analyses for the passive jettision condition. The recommended altitude and speed of aircraft was suggested as design criteria of aerodynamic breakaway capability of jettisonable canopy system as a bakup egress method when normal canopy jettison sequence malfunctioned. Aerodynamic breakaway condition of jettisonable canopy was also simulated and the fracture load conditions of canopy actuator were investigated.
순환기가감방(循環器加減方)이 고지혈증 유발 백서(白鼠)에 미치는 영향
김동현,임승민,안정조,조현경,유호룡,김윤식,설인찬,Kim, Dong-Hyun,Lim, Seung-Min,Ahn, Jung-Jo,Jo, Hyun-Kyung,Yoo, Ho-Ryong,Kim, Yoon-Sik,Seol, In-Chan 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.3
Objective : This study was performed to investigate the effect of Sunhwangigagambang(SHG) on hyperlipidemia in SD rats induced by high cholesterol diet. Method : After treatment with SHG, cytotoxicity, body weight, liver weight, AST, ALT, ALP, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, glucose, albumin, total protein in serum, malondialdehyde, and gene expression for ACAT and HMG-CoA reductase in hepatic tissue were analyzed. Result : 1. SHG didn't show any cytotoxicity in both human fibroblast cell line and SD rats. 2. SHG significantly inhibited the increase of liver weight by high cholesterol diet compared to the control group. 3. SHG significantly ameliorated the increase of total cholesterol, LDL-cholesterol, and triglyceride and reduction of HDL-cholesterol compared to the control group. 4. SHG significantly reduced glucose level in serum compared to the control group. 5. SHG significantly reduced malondialdehyde in hepatic tissue compared to the control group. 6. SHG significantly down-regulated gene expression of ACAT and HMG-CoA reductase compared to the control group. Conclusion : These results suggest that SHG might be effective in treatment and prevention of hyperlipidemia.
김동현 ( Dong Hyun Kim ),김효남 ( Hyo Nam Kim ) 한국과학교육학회 2011 한국과학교육학회지 Vol.31 No.8
The purpose of this study was to analyze and extract the features of verbal interactions between teacher and science-gifted students in their classes. For the purpose of this study, authors observed 27 elementary science classes for the science gifted of three elementary teachers. To analyze the verbal interactions in the classes, the authors have adopted the theoretical background, which was based on Sinclair & Coulthard`s Initiative-Response- Feedback pattern. Verbal interactions in the classes were analyzed by Kim`s framework, which modified Jeong`s framework. IRF patterns were derived from the verbal interactions of science classes for the science gifted. As a result, authors obtained some important features in IRF pattern. The most commonly used IRF pattern was the teacher`s managerial question-student`s short answer pattern, which was due to the regional policy for the science gifted. The teacher`s delayed feedback as well as the teacher`s question was meaningful for student`s thinking ability. If elementary teachers consider the pattern, the strategy should be applied, which is depending on student levels and levels of contents. But three teachers did not show the characteristic verbal interaction regarded as a pattern strategy. In the future, inservice programs about verbal interaction are needed for the science gifted classes.
Capsaicin 적용 후 손상된 흰쥐 척수내 c-fos와 HSP70의 발현
김동현,김석범,백수정,김진상,Kim, Dong-Hyun,Kim, Souk-Boum,Baek, Su-Jeong,Kim, Jin-Sang The Korean Society of Physical Therapy 2002 대한물리치료학회지 Vol.14 No.1
C-fos는 원종양유전자(proto-oncogene)인 v-fos의 세포 동족체로써, 성장인자나 신경전달 물질에 의해 수분 내에 다양한 형태의 세포에서 활성화된다. Fos단백질은 스트레스와 통증 과정의 신호전달기전에서 세포활동을 조절하는 3차전령으로 활동한다. 열충격 단백질(Heat shock protein : 이하 HSP)은 계통발생학적으로 초기 척추 동물에서부터 발현되며 생체방어체계의 중요한 인자로 세포가 고열, 외상, 허혈 등의 스트레스에 직면했을 때 발현이 증가하는 단백질로 알려져 있다. 본 연구에서는 캡사이신(capsaicin)으로 말초 신경병변을 유발시킨 후 통각신경활성의 지표로 이용되는 원종양 유전자인 c-fos의 발현과 열 또는 스트레스로 야기되는 손상에 대한 조직의 방어작용으로 발현되는 HSP 70의 발현을 동시에 관찰함으로서, 급성으로 유발된 말초 신경병변의 확인과 동시에 실험동물 체내에서 방어적인 역할을 밝히는 일환으로 이 실험을 실시하였다. 본 실험의 결과는 다음과 같다; 1. 척수 등쪽뿔 천층(Laminae I and II)에서 각각 c-fos와 HSP70을 항원으로 하는 면역조직화학적 방법으로 염색한 표본에서 0.9% NaCI 투여 2시간 후 c-fos와 HSP70의 양성을 나타내는 세포는 전혀 없음을 알 수 있었다. 2. 척수 등쪽뿔 천층에서 c-fos 단백질을 항원으로 하는 면역조직화학적 방법으로 염색한 표본에서 Capsaicin 투여 2시간 후 c-fos 단백질에 양성을 나타내는 세포가 많이 발현됨을 육안적 관찰로서 알 수 있었다. 3. 척수 등쪽뿔 천층에서 HSP70을 항원으로 하는 면역조직화확적 방법으로 염색한 표본에서 Capsaicin 투여 2시간 후 HSP7O의 양성을 나타내는 세포가 보통수준으로 발현됨을 육안적 관찰로서 알 수 있었다. 이 실험의 결과로 볼 때, 화학적인 신경병변 유발물질에 의한 손상을 방어하기 위해서 체내에는 내인성 물질이 형성될 것이라는 추측과 c-fos 가 다른 유전자의 발현을 유도한다는 점을 함께 고려 하였을때, Capsaicin에 의한 말초 신경병변에서 c-fos 발현이 많이 나타나는 것은 손상을 방어하는 물질의 생성에 관여하기 때문이며, 방어물질 중 이 실험에서 본 HSP70도 증가한 내인성 방어물질의 하나라고 할 수 있을 것이다.
GaAIAs 레이저 조사가 흰쥐 창상부위 상피조직의 EGF 발현에 미치는 영향
김동현,백수정,배주한,김석범,권영실,김진상,Kim, Dong-Hyun,Baek, Su-Jeong,Bae, Ju-Han,Kim, Suk-Bum,Kwon, Young-Shil,Kim, Jin-Sang 대한물리치료학회 2001 대한물리치료학회지 Vol.13 No.3
This study was performed. using EGF, to observated the effect of GaAIAs laser on wound model induced designedly in lumbar region. The results of this study were as following: 1. In expression of EGF which used marker of wound healing, laser irradiating group made EGF to more induce significantly than laser non-irradiating group at 3 days. 2. EGF immunoreactivity in epidermis were increased markedly 3 days after wound, and increased gradually from 1 day to 2 days in wound which is laser irradiation. Therefore, EGF immunoreactivity which increased after wound with GaAIAs laser irradiation indicate that GaAIAs laser have wound healing effect. This study also can become a part of scientific evidence on electrotherapy through measuring quantitively effects of GaAIAs laser in wound
식용 식물자원으로부터 활성물질의 탐색 -XIII. 개망초(Erigeron annuus L.) 꽃으로부터 triterpenoid의 분리-
김동현,정성제,방명호,정인식,김성훈,권병목,김대근,박미현,백남인,Kim, Dong-Hyun,Jung, Sung-Je,Bang, Myun-Ho,Chung, In-Sik,Kim, Sung-Hoon,Kwon, Byoung-Mog,Kim, Dae-Keun,Park, Mi-Hyun,Baek, Nam-In 한국응용생명화학회 2004 Applied Biological Chemistry (Appl Biol Chem) Vol.47 No.4
개망초의 꽃을 80% MeOH 용액으로 추출하고, 추출물을 EtOAc, n-BuOH 및 물로 분배, 추출하였다. 이 중 EtOAc 분획을 silica gel, octadecylsilica gel(ODS) column chromatography 및 high performance liquid chromatography(HPLC)로 정제하여 3종의 화합물을 분리하였다. 각 화합물의 화학구조는 NMR, MS 및 IR 등의 스펙트럼 데이터를 해석하여, ${\alpha}-amyrenone(1),\;{\alpha}-amyrin(2)$ 및 ${\beta}-amyrin(3)$으로 동정하였다. 이들 3종의 triterpenoid는 개망초에서는 처음 분리되었다. The flower of Erigeron annuus L. was extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with EtOAc, n-BuOH and $H_2O$, successively. From the EtOAc fraction, three compounds were isolated through the repeated silica gel, ODS column and high performance liquid chromatographies. From the result of physico-chemical data including NMR, MS and IR, the chemical structures of the compounds were determined as ${\alpha}-amyrenone,\;{\alpha}-amyrin\;and\;{\beta}-amyrin$. These three compounds were isolated for the first time from the flower of Erigeron annuus L.
ICT 기반의 인삼 공정 육묘 시 질소 형태와 게르마늄(Ge) 유무가 생장에 미치는 영향
김동현,김연복,구현정,백현진,이수빈,최지혜,홍의기,장광진,Dong Hyun, Kim,Yeon Bok, Kim,Hyun Jung, Koo,Hyun Jin, Baek,Su Bin, Lee,Jeei Hye, Choi,Eui Gi, Hong,Kwang Jin, Chang 국립한국농수산대학교 교육개발센터 2022 현장농업연구지 = Journal of practical agricultural resear Vol.24 No.4
Ginseng hydroponic cultivation was cultivated as a nutrient solution and the growth was investigated 60 days later. The length(cm) increased from EC1.0 and EC2.0 concentrations to 5.47cm before, followed by EC0.5, 2.5, 1.5, and 0.0. The weight(g) increased from EC1.0 concentration to 2.39g before, followed by EC1.5, 2.5, 0.5, 0.0 and 2.0. The width(mm) increased from EC1.0 concentration to 1.9mm than before, followed by EC2.5, 0.5, 1.5, 2.0, and 0.0. In the ginseng growth experiment according to nutritional components, the average length of NO<sub>3</sub>-N mixed experiment increased to 0.33cm, the average weight of 0.04g, and the average width of 0.35mm. In the experiment in which NH<sub>4</sub>-N was mixed without NO<sub>3</sub>-N, the growth was reduced to 0.37cm in average length, 0.03g in average weight, and 0.22mm in average width. In an experiment in which germanium(Ge) is mixed with a nutrient component, the average length is increased to 0.33cm, the average weight is increased to 0.04g, and the average width is increased to 0.35mm, but in an experiment excluding germanium(Ge), the growth is reduced to 0.11cm, the average weight is 0.04g, and the average width is 0.03mm.
슬러지 폐기물을 활용한 반도체급 균일한 콜로이달 실리카 나노입자의 제조 및 CMP 응용
김동현,김지원,제갈석,김민정,김하영,김민상,김상춘,박선영,윤창민,Kim, Dong Hyun,Kim, Jiwon,Jekal, Suk,Kim, Min Jeong,Kim, Ha-Yeong,Kim, Min Sang,Kim, Sang-Chun,Park, Seon-Young,Yoon, Chang-Min 유기성자원학회 2022 유기물자원화 Vol.30 No.3
This study suggests the effective recycling method of sludge waste from various industrial fields to synthesize uniform colloidal silica nanoparticles. In detail, polymers are removed from the sludge waste to attain sludge-extracted silica (s-SiO<sub>2</sub>) micron-sized particles, and ammonia assisted sonication is applied to s-SiO<sub>2</sub>, which has effectively extracted the silanol precursor. The nano-sized silica (n-SiO<sub>2</sub>) particles are successfully synthesized by a typical sol-gel method using silanol precursor. Also, the yield amounts of n-SiO<sub>2</sub> are determined by the function of s-SiO<sub>2</sub> etching time. Finally, n-SiO<sub>2</sub>-based slurry is synthesized for the practical CMP application. As a result, rough-surfaced semiconductor chip is successfully polished by the n-SiO<sub>2</sub>-based slurry to exhibit the mirror-like clean surface. In this regard, sludge wastes are successfully prepared as valuable semicondutor grade materials.
김동현,백수정,김석범,송주민,김진상,Kim Dong-Hyun,Baek Su-Jeong,Kim Suk-Bum,Song Ju-Min,Kim Jin-Sang 대한물리치료학회 2002 대한물리치료학회지 Vol.14 No.2
This study was performed, using c-fos and Substance P, to investigate the effect of GaAlAs laser on acute pain model induced by wound in lumbar region's spinal level. The test group was divided into control and experimental group. Control group is shamed group(c-fos and substance P expression after non-irradiation by a GaAlAs laser), The experimental group was divided into two subgroups: one is experimental group I (c-fos expression after irradiation by a GaAlAs laser), and the other is experimental group II (substance P expression after irradiation by a GaAlAs laser). The results of this study were as following: 1. The numbers of c-fos immunoreactive neuron in spinal cord was increased markedly 1 day after wound, and decreased gradually from 1 day to 2 days in wound with GaAlAs laser irradiation. 2. The changes of the average percentages of substance P immunoreactive neurons in spinal cord was increased markedly 1 day after wound, and decreased gradually from 1 day to 2 days in wound with GaAlAs laser irradiation. Therefore, decreasing the changes of c-fos and substance P expression after irradiation by a GaAlAs laser indicates and GaAlAs laser have effect on pain control.