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피크노제놀을 함유한 화장품이 40~50대 한국 여성의 피부에 미치는 영향 - 피부임상학적 접근
김경연,구정은,Kim, Kyung-Yun,Ku, Jung-Eun 한국융합학회 2021 한국융합학회논문지 Vol.12 No.8
Pycnogenol extracted from pine bark is a component with great antibacterial activity and antioxidant effect. It is applied as a natural anti-inflammatory agent with various medical effects including anti-inflammatory effects, regulation of blood pressure, regulation of the immune system, and inhibition of cancer cell growth. However, research related to cosmetics is limited. Therefore, in this study, the effect of Pycnogenol on the skin was studied through a clinical approach. Changes in skin condition were observed after using cosmetics with Pycnogenol and without Pycnogenol for 6 weeks for 10 clinicians in each group. We observed the effect of pore reduction, wrinkle reduction around eyes, a decrease of the number and angle of loose pores, and reduction of pigmentation. Therefore, cosmetics containing Pycnogenol have the effect of improving skin problems of aging skin. 소나무 수피에서 추출한 Pycnogenol은 항균활성과 항산화 효과가 뛰어난 성분으로 항염, 혈압조절기능, 면역조절, 암세포 성장억제 등 다양한 의학적 효능과 함께 천연 소염제로 응용되고 있지만 화장품 관련 연구는 미비한 상황이므로 본 연구는 Pycnogenol 성분이 피부에 미치는 효과를 임상학적 접근한 연구이다. Pycnogenol 성분 첨가, 무첨가한 화장품을 각 각 10명의 임상자가 6주간 사용하게 한 후 피부 상태 변화를 살펴보았으며 모공의 감소, 눈가주름의 감소, 처진모공의 개수와 각도의 감소, 색소침착이 감소하는 효과가 있었다. 그러므로 Pycnogenol 성분을 함유한 화장품은 노화피부에서 나타나는 피부 문제를 개선하는 효과가 있다.
김경연,이승희,오복자 대한종양간호학회 2015 Asian Oncology Nursing Vol.15 No.3
University, Seoul, Korea Purpose: The purpose of this study was to assess chemotherapy induced peripheral neuropathy (CIPN) and to examine the relationship between CIPN and depression. Methods: A purposive sample of 105 patients treated with chemotherapy were recruited in the cross-sectional survey design. Data were collected using self-report questionnaires. The instruments used were the Chemotherapy Induced Peripheral Neuropathy Assessment Tool (CIPNAT) and Hospital Anxiety Depression Scale (HADS). Results: The most frequent suffering symptom of CIPN was ‘tingling feeling in the hand and foot’. Of the motor symptoms, ‘muscle weakness’ was the most frequent symptom and ‘muscle or joint aches’ was the strongest suffering symptom of CIPN. The mean score for suffering of CIPN was 4.1. The mean score was 1.04 for depression and the prevalence was 48.5%. CIPN was significantly positively correlated with depression (r=.38, p<.001). The result of simple regression analysis revealed that CIPN was predictive of depression (R2=.136, p<.001). Conclusion: Based on the findings of this study, nursing intervention programs focusing on CIPN management and alleviating