신생아 중환자실의 원내 감염 추이

권혜정,김소연,조창이,최영륜,신종희,서순팔,Kwon, Hye Jung,Kim, So Youn,Cho, Chang Yee,Choi, Young Youn,Shin, Jong Hee,Suh, Soon Pal 대한소아청소년과학회 2002 Clinical and Experimental Pediatrics (CEP) Vol.45 No.6

목 적: 신생아 집중 치료술의 발달로 고위험 신생아의 생존율이 많이 개선되었지만 적극적인 침습적 시술의 증가로 신생아 사망과 이환의 주요한 원인이 되는 신생아 감염의 발생은 오히려 높아졌다. 본 연구는 신생아 중환자실에서 원내 감염의 분포 양상, 원인균, 발생 빈도 및 변화 양상 등 5년간의 추이를 알아보기 위해 실시하였다. 방 법: 1995년 1월부터 1999년 12월까지 전남대학교병원 신생아 중환자실에 입원하여 혈액, 피부, 기관내 튜우브, 카테테르, 눈, 소변, 대변, 뇌 척수액에서 시행한 균 배양 검사 상 양성으로 나온 환아들 중 선천성 감염을 제외하고 임상 증상으로 원내 감염이 의심되었던 환아들에서 원내 감염의 분포 양상과 원인균 및 혈중 감염의 빈도, 원인균, 사망률 추이에 대하여 조사하였다. 결 과 : 5년 동안 신생아 중환자실에 입원한 환아의 원내 감염률은 입원 환아 100명당 9.0례이었고, 감염소로는 혈중 감염이 32.3%로 가장 많았으며, 피부(18.4%), 기관내 튜우브(17.2%), 카테테르(10.6%), 눈(10.0%), 소변(6.1%), 대변(3.0%), 뇌 척수액(2.4%) 순이었다. 원인균은 S. aureus가 29.9%로 가장 많았고 coagulase-negative staphylococci(CONS), Enterobacter,Candida 순이었다. 감염소별 원인균은 혈중과 카테테르는 S. aureus와 CONS, 피부와 눈은 S. aureus, 기관내 튜우브는 Enterobacter, 소변은 Candida와 enterococci, 그리고 대변은 Pseudomonas와 S. aureus가 흔하였고, 다병소 감염율은 26.1%이었다. 원내 감염률은 입원 환아 100명당 1995년 9.5례에서 1999년 11.6례로 증가하였으며, 원인균으로 S. aureus 는 감소하고 CONS, Candida, Klebsiella, Acinetobacter baumannii는 증가하는 추이를 보였다. 동기간 동안 혈중 감염률은 입원 환아 100명당 3.6례였으며, CONS와 S. aureus가 가장 많았다. 혈중 감염률은 입원 환아 100명당 1995년 2.1례에서 1999년 5.2례로 증가하였는데 원인균으로 S. aureus는 감소하고 CONS, Candida, Klebsiella, Acinetobacter baumannii는 증가하는 추이를 보였고, 패혈증에 의한 사망률은 11.9%이었다. 결 론 : 신생아 원내 감염의 가장 흔한 감염소는 혈중 감염이고 원인균으로는 S. aureus가 가장 흔하며, CONS, Candida, Klebsiella, Acinetobacter baumannii에 의한 감염은 증가하는 추이이므로, 이에 대한 예방 및 치료를 위한 노력이 필요할 것으로 사료된다. Purpose : Neonates in neonatal intensive care units(NICU) have a high risk of acquiring nosocomial infection because of their impaired host defence mechanism and invasive procedures. Nosocomial infection result in considerable morbidity and mortality among neonates. This study was carried out to survey both the epidemiology of nosocomial infection in our NICU and the annual trends of pathogens. Methods : We retrospectively reviewed culture proven nosocomial infection which occurred in our NICU from January 1995 to December 1999. The data included clinical characteristics, site of infection, pathogens, and mortality. Results : Nosocomial infection rates was 9.0 per 100 NICU admissions during the five-year period. Major sites of infection were bloodstream(32.3%), skin(18.4%), endotracheal tube(17.2%), and catheter(10.6%). The most common pathogen was S. aureus(29.9%). and the others were coagulase- negative staphylococci(CONS)(14.8%), Enterobacter(12.4%), and Candida(9.0%). During the five-year period, nosocomial infection rates increased from 9.5 to 11.6 per 100 admissions with the increase of CONS, Candida, Klebsiella, and Acinetobacter baumannii. The infection rate of S. aureus decreased. Multiple episodes of nosocomial infection occurred in 26.1% of all nosocomial infections. Overall bloodstream infection rates were 3.6 per 100 NICU admissions during five years. CONS(29.1%) and S. aureus(27.1%) were the two most common pathogens. Increasing rates of bloodstream infection by CONS, Candida, Klebsiella, and Acinetobacter baumannii were observed. Bloodstream infection related mortality was 11.9%. Conclusion : The predominant pathogens of nosocomial infection in NICU were S. aureus and CONS. Bloodstream infection, the most frequent nosocomial infection, should be a major focus of surveillance and prevention efforts in NICU.

직장에서 실시하는 스트레칭

권혜정 한국산업간호협회 2001 한국산업간호협회지 Vol.8 No.1

조선 후기 규원가류 가사의 문학교육적 의미 탐색 - 이용기 편 『(고대본)樂府』 소재 <閨怨歌> 異本을 중심으로 -

권혜정 한국문학교육학회 2019 문학교육학 Vol.0 No.62

The aim of this paper is to search the educational value of late Gasa(歌辭), which is widely possessed in late Choseon dynasty. And it focused on Gyuwonga group of Gasa. For this purpose, I examined the changes in the way of possession that is resulted from expansion of charging group in late Choseon period and confirmed the context of possession about 『Akbu(樂府)』. The direction and purpose of compilation is basis for understanding the texts in the Gasa-Anthologies. Gyuwonga group of Gasa in 『Akbu(樂府)』 are almost the same as <Gyuwonga>, which is written by Heonanselheon. But changes in way of possession brought about the change in discourse. It is similar to the popular love lyrics of that period. For this reason, it can be understood as a conventional love song. <Chyeongruwon-byeolgok> is the most unique version of Gyuwonga group of Gasa. It has added lines the back of the original text. With the added text, we can see the characteristics of popular culture of late Gasa. We can rediscover the value of Canon in literary education by looking through the Gyuwonga(閨怨歌) group of Gasa. It also helps us understand the popular cultural properties of late Gasa and shows the possibility of creating a literary culture centered on those who enjoy it. These are the literary and educational values of the late Gasa. 이 연구는 조선 후기에 널리 향유된 규원가류 가사를 중심으로 후기 가사의 문학교육적 가치를 탐색하는 것에 목적을 두었다. 이를 위하여 조선 후기 가사 담당층의 확대에 따른 향유방식의 변화를 살피고, 이용기 편 『(고대본)樂府』의 향유 맥락을 확인하였다. 가사집의 편찬 방향과 목적은 가사 향유의 정황을 반영한다는 점에서 해당 가집 소재의 텍스트를 이해하는 기반이 되기 때문이다. 『(고대본)樂府』 소재의 규원가류 가사는 허난설헌의 <규원가>와 내용과 형식면에서 거의 동일하나 향유층의 확대에 따른 향유목적 및 방법의 변화로 인한 담론의 전환을 보여준다. 또한 당대 유행했던 상사가류들과의 친연성에서 통속적 사랑 노래로의 이해 가능성을 보여준다. <쳥루원별곡(靑褸怨別曲)>은 가장 특이성을 보이는 이본으로 결사 뒤에 덧붙여진 텍스트를 통해 풍류의 공간에서 불린 대중적 가창물의 성격을 보인다는 점에서 의미가 있다. 조선 후기 규원가류 가사를 통해 정전 텍스트의 문학교육적 의미를 재탐색할 수 있다는 점과, 가사가 지닌 대중문화적 속성을 이해하고 향유자 중심의 문학적 문화 형성의 가능성을 인식할 수 있다는 점에서 후기 가사의 문학교육적 가치를 확인할 수 있다.

감각통합치료가 뇌성마비 아동의 감각.운동발달 및 적응행동에 미치는 영향

권혜정,Kwon, Hye-Jeoung 대한물리치료과학회 2001 대한물리치료과학회지 Vol.8 No.2

The purpose of this study was to examine the effects of sensory integration therapy (SIT) on sensory' motor development and adaptive behavior of cerebral palsy children. The design of this study was quasi experiments with a non-equivalent pre- and post-test control design. Subjects of the study were arbitrarily chosen based on predetermined selection criteria among the cerebral palsy children who were treated as out-patients at two rehabilitation hospitals one in Seoul, and the other in Kyunggi-do. The study was conducted between early April and late July in 2000. Fifteen children were in the experimental group and eleven in the control group. The allocation was done based on ease of experimental treatment. A five-step SIT program was devised from a combination of SIT programs suggested by Ayres(1985) and Finks(1989), and an author-designed SIT program for cerebral palsy children. The experimental group was subjected to 20 to 30 minutes of SIT per session. two sessions a week for ten -week period. The effects of SIT were measured with respect to 9 sub-areas that can be administered to cerebral palsy children out of a total of 17 sub-areas in the Southern California Sensory Integration Test (SCSIT) developed by Ayres (1980). In addition. the scale developed by Russell (1993) for Gross Motor Function Measure (GMFM). and Perception Motor Development Test developed by 中司利一 et al.(1987) were also applied. Adaptive behavior was analyzed using guidelines in two unpublished documents - School-Age Checklist for Occupational Therapy by the Wakefield Occupational Therapy Associates, and the OTA-Watertown Clinical Assessment by the Watertown Occupational Therapy Associates-, and an author-developed Adaptive Behavior Checklist. Collected data were statistically analyzed by SPSS PC for chi square test, Mann-Whitney test, Wilcoxon signed rank test, and paired t-test. The results were as follows: 1. In sensory development, the experimental group exhibited a score increase compared to the control group, but the difference was not statistically significant, Although the experimental group showed improvements in all. 9 sub-areas compared to the control group, only right-left discrimination exhibited statistically significant change. 2. In gross motor development, the experimental group showed improvements in score compared to the control group, but it was not statistically significant. In fine motor development, the experimental group exhibited statistically significant improvements compared to the control group. In sub-area analysis, figure synthesis showed positive change. 3. In adaptive behavior development, post-experimental adaptive behavior scores were higher compared to pre-experimental scores with statistical significance. Furthermore, sub-areas emotional behavior, perception behavior, gross-fine motor function, oral-respiration function, motor behavior, motor planning, and adaptive response exhibited higher scores after SIT. In conclusion SIT was found to be partially effective in sensory and fine motor development, effective in all adaptive behavior areas, and not effective in gross motor development. Thus, this study has shown that SIT is an effective intervention for sensory development, fine motor development, and adaptive behavior for cerebral palsy children. But, for the effectiveness of SIT on gross motor development, further studies employing longer-time experiments are recommended.

강원 신육성 잡곡(수수, 조, 기장)별 이화학적 특성 및 생리활성 비교

권혜정,이재영,이하연,임계현,김선영,염은경 한국식품영양과학회 2015 한국식품영양과학회 학술대회발표집 Vol.2015 No.8

Fenton 산화 전처리를 통한 RO 농축폐수의 생물학적 처리

권혜정,이선주,유영범,전항배 한국수처리학회 2019 한국수처리학회지 Vol.27 No.1

Physicochemical pre-treatments are required to treat RO (Reverse osmosis) waste water because non-degradable organic matter and high concentrated nutrients are included in RO waste water. In this study, therefore, fenton pre-treatment process was applied to improve biodegradability and biological treatment efficiency of RO waste water. COD (Chemical oxygen demand), BOD (Biological oxygen demand), T-N (Total nitrogen), T-P (Total phosphorus), and pH of raw RO waste water were 154.4 ±27.8 mg/L, 78.9 ±19.4 mg/L, 117.0 ±21.8 mg/L, 2.0 ±0.4 mg/L, and 7.5 ±0.4, respectively. Fenton process enhanced biodegradability of RO waste water from 51% to 69%. Biological COD removal efficiencies with fenton and without fenton were 48.6 and 68.0%, respectively. Since the low COD concentration in raw RO waste water, T-N removal efficiency was not improved in MBR (Membrane bio-reactor) although fenton process was operated to improve biodegradability. These results show that the organic carbon for the biological denitrification was lacked in biodegradability improved RO waste water and the additional organic carbon was required to remove nitrogen. T-P was mainly removed by precipitation of floc formed in fenton process. The recirculation of fenton sludge without additional injection of fenton reagent was not effective to maintain pre-treatment efficiency. These result indicates that continuous injection of fenton reagent is required to maintain efficiency of fenton pre-treatment and amount of fenton reagent can be reduced by recirculation of fenton sludge.

일과성 갑상선중독증에 동반된 갑상선 중독성 주기성 마비 1예

권혜정,최영식,이준섭,박동현,최윤정,유진석 고신대학교(의대) 고신대학교 의과대학 학술지 2012 고신대학교 의과대학 학술지 Vol.27 No.2

Thyrotoxic periodic paralysis is an acute muscle weakness of the limbs associated with hypokalemia. It can occur with any form of thyrotoxicosis. Thyrotoxic periodic paralysis associated with transient thyrotoxicosis due to thyroiditis is very rare. We experienced a case of thyrotoxic periodic paralysis associated with transient thyrotoxicosis. A 39-yr-old man was referred to our hospital because of paralysis of upper and lower extremity. The laboratory results were hypokalemia and mild thyrotoxicosis. A thyroid scan with Tc-99m revealed decreased uptake in the thyroid area compatible with destructive thyroiditis. The paralytic attack did not recur after the patient recovered to euthyroid state.

보조 미생물 전기화학적 반응조가 혐기성소화조에서 음식물류폐기물로부터 메탄생성에 미치는 영향

권혜정,전항배 대한환경공학회 2018 대한환경공학회 학술발표논문집 Vol.2018 No.11

왕고들빼기「선향」품종의 정식시기 및 수확횟수에 따른 이화학적 특성 및 생리활성 비교

권혜정,정은경,윤미순,임계현,이효영,박아름,노희선,허남기 한국식품영양과학회 2014 한국식품영양과학회 학술대회발표집 Vol.2014 No.10

왕고들빼기「선향」품종 및 야생종의 부위별 추출용매별 생리활성 비교

권혜정,정은경,한설지,정혜정,노희선,김시창,허남기 한국식품영양과학회 2013 한국식품영양과학회 학술대회발표집 Vol.2013 No.11