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수술전 영양결핍상태의 위암 환자에 대한 Solgreen^�(12.5% aminoacid)의 투여 효과
강민규,노승무,장일성 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.2
The effects of Solgreen (12.5% aminoacid) injection was evaluated in 22 stomach cancer patients with preoperative nutritional deficiency. In this study, 500㎖ of Solgreen was intravenously injected daily for 5 days in 16 patients (A group) and Solgreen was not injected in 6 patients (B group). 24 hour urine creatinine, creatinine-height index (reflects body protein) and serum albumin were measured. The results were as follows: 1. Increase in creatinine-height index was greater in Solgreen injected group than non-injected group. 2. Among group of Solgreen injection, creatinine-height index was higher in post-injection day than in pre-injection day. 3. Increase in serum albumin was greater in Solgreen injected group than non-injected group.
중소기업 연구개발 역량 강화의 인과순환구조: 의료기기 제조기업 A사 사례 분석
강민규,임효숙 한국시스템다이내믹스학회 2023 한국시스템다이내믹스 연구 Vol.24 No.4
This study focuses on the case of Company A, a medical device manufacturer, to identify the causal structures of R&D capability enhancement in SMEs. Company A successfully developed new products, leading to sales growth and company size due to enhancing its R&D capability. The CEO’s decisions to secure R&D researchers and invest increased revenue in hiring additional R&D researchers and improving working conditions led to a virtuous cycle of R&D capability enhancement. The causal loop diagram (CLD) around the case of Company A showed multiple reinforcing feedback loops. The causal loop structure suggests that government support for SMEs can make an initial contribution to the R&D capability building but has limits. The strategic decisions and management of the company are more important than external support, such as the government.
유체 구조 연성 해석기법을 이용한 고속발사체에 미치는 공력의 수치해석적 연구
강민규,박동진,이석순,Kang, Mingyu,Park, Dongjin,Lee, Seoksoon 항공우주시스템공학회 2012 항공우주시스템공학회지 Vol.6 No.4
This paper is focusing on the define the safety of high speed projectiles from aerodynamic load. The Fin loaded from aerodynamic is the roll of high speed projectile's gide. The Fin can rotate about 25deg as maximum, and it has maximum aerodynamic load with 25deg position. For finite element analysis from aerodynamic load, fluid analysis will be conducted before structure analysis and export pressure data. The pressure data will be used as load condition at structure analysis of Fin. The result of structure analysis of Fin, there is some stress concentration and stress closed with yield stress of material. But this problem will be solved with change to another material.
강민규,김주영,정재우,송우정,조상헌,민경업,강혜련 대한천식알레르기학회 2013 Allergy, Asthma & Immunology Research Vol.5 No.6
Purpose: Long-term asthma management is recommended to asthmatics; however, many patients do not adhere to follow-up treatment. It is unclearwhy many asthmatics do not adhere to follow-up treatment and long-term clinical course after discontinuation of asthma management. Thisstudy investigates the factors associated with loss to follow-up and observes the clinical course in asthmatics who discontinued asthma treatment. Methods: A retrospective investigation was conducted after reviewing medical records of adult patients who were newly diagnosed with asthmaat a university hospital in Seoul, South Korea from January 2005 to March 2007. We compared baseline demographics and the clinical and laboratoryprofiles of patients to see if they successfully adhered to the treatment at an outpatient clinic for at least 3 years. The clinical course and asthmacontrol status were surveyed by telephone for patients who were lost to follow-up within 3 years. Results: A total of 351 (73.9%) out of 475 patientswere lost to follow-up within 3 years of asthma diagnosis. Patients lost to follow-up were younger and had clinical features of less severeasthma at time of diagnosis (higher FEV1 and PC20, and lower grade treatments) compared to patients who adhered to the follow-up for longer than3 years (all P<0.05). Among the 198 responders to the telephone survey, 124 responders (62.6%) answered that they eventually discontinued asthmamedication. A significantly higher proportion of the 124 responders who discontinued asthma treatment maintained symptom improvement comparedto the 74 responders who continued asthma medication (77.4% vs. 55.4%, P=0.003). Conclusions: Almost three quarters of newly diagnosedasthmatics discontinued asthma medication within 3 years despite a medical recommendation. There are considerable numbers of asthmaticswho can maintain long-term asthma control status without medication.
Intraoperative Radiotherapy for Locally Advanced Rectal Cancer
강민규,김명세,김재황 대한대장항문학회 2010 Annals of Coloproctolgy Vol.26 No.4
Purpose: Although intraoperative radiotherapy (IORT) is known to be a method that can reduce local recurrence in locally advanced colorectal cancer, it is not widely used. The aim of this study was to report our experience with IORT for locally advanced rectal cancer. Methods: From 1991 to 1994, nine patients with locally advanced rectal cancer received IORT. External beam radiotherapy was given postoperatively in five patients and preoperatively in three. Seven patients received chemotherapy. IORT was done with 6-MeV or 9-MeV electrons, and 12 Gy was irradiated at the tumor bed. The median follow-up period was 84 months (range, 15 to 208 months). Results: The median age of patients was 51 years (range, 42 to 73 years). All patients had advanced clinical T-stage (cT3/4)cancer. The overall and the disease-free survival rates were 66.7% and 66.7% at 5 years, respectively. One patient developed a local recurrence near the anastomosis site, which was out of the IORT field. Four patients died before the last follow-up;three from distant metastasis and one from secondary primary cancer. Adverse effects related to IORT did not occur. Conclusion: Although the number of patients was small in this study, IORT is thought to be safe and effective in reducing local recurrence in locally advanced rectal cancer. However, the role of IORT should be refined in the era of preoperative radio-chemotherapy followed by total mesorectal excision.