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      • KCI등재후보
      • KCI등재

        솔잎 추출물이 진피섬유아세포에서 콜라겐 발현 및 생성에 미치는 영향

        김창수,리순화 한국피부과학연구원 2012 대한피부미용학회지 Vol.10 No.4

        By using Pini Folium of Pinus densiflora Seib. et Zucc. that naturally grow in Gangwon-do area, cytotoxicity resistance effect against NHDF were examined and a study on the mRNA expression of COL1A1 and generation effect of pro-collagen 1 was conducted. After extracting Pini Folium with 80% ethanol and hot water respectively and they were referred to as PEF and PFW. The cytotoxicity resistance effect of pine needles was examined by conducting MTT assay, TNF-α, and H2O2 test regarding NHDF. The amount of COL1A1expression using qRT-PCR and the generation of pro-collagen 1 using Western blot were examined. As a result of the experiment, In MTT assay, PFE, PFW had no cytotoxicity against the hypodermal cell. As a result of cell death resistance effect on TNF-α, PFE displayed a significant result in the concentration of 10 μg/mL and PFW displayed non signifiant result. In the effects on cell death resistance of H2O2, PFE and PFW could be confirmed to have significant results. In regards to the measurement of mRNA expression of COL1A1 , PFE displayed non-significant difference, PFW displayed significant difference. In regards to the generation of procollagen 1, the protein was generated for both PFE, PFW. In conclusion, PFE and PFW of Pini Folium extract can be applied to skin beauty practically and considered as the results to suggest the anti-aging possibility in aging skin in regards to mRNA expression of COL1A1 against NHDF and generation of pro-collagen 1.

      • KCI등재

        지방정부의 협력적 정책기획의 경험과 성공조건

        김창수 한국지방정부학회 2009 지방정부연구 Vol.13 No.1

        본 연구는 기피시설 입지를 위한 경기도의 인근 3개 지방정부 정책기획의 성공과 실패 경험을 소개하면서 협력적 정책기획의 성공조건을 모색하고자 했다. 선행연구의 건토결과 정책목표에 대한 합의 포용적이고 투명한 정책과정, 정책참여자들의 함께 일하는 책임감, 반대의견에 열려있는 협력적 리더십이 협력적 정책기획의 성공을 위한 중요한 조건으로 도출되었다. 사례분석결과 구리시는 4가지 조건에 충실하여 쓰레기소각장을 위한 협력적 정책기획을 성공적으로 추징하여 원하는 정책효과를 얻을 수 있었다. 그러나 독단적이고 폐쇄적인 정책기획을 추진한 남양주시의 소각잔재매립장과 하남시의 광역화장장의 경우 높은 정책비용을 초래하면서 원하는 정책효과를 얻지 못한 것으로 나타났다. 그러므로 본 연구에서는 지방정부가 도심하천 살리기와 같은 비교적 갈등이 작은 사안뿐만 아니라 기피시설 입지정책처럼 갈등이 매우 큰 사안 역시 협력적 정책기획의 지혜를 발휘해야만 입지결정과 정책집행이 원활함을 제안했다. The purpose of this paper is to explore the successful conditions of collaborative policy planing in local governments. The agreement of policy goals, inclusive and transparent policy process, the responsibility of policy participants, and cooperative leadership were considered as the main factors for the framework of this study about location conflicts of the unwanted public facilities. For this purpose, I analyzed the experiences of collaborative policy planning in 3 adjacent local governments which experienced location conflicts dealing with unwanted public facilities. I found out that the waste incinerator created in Guri city was successfully established by meeting the conditions of collaborative policy planning. I also found out that the trash-incinerated ashes disposal facilities created in Namyangju city and the large regional cremation facilities created in Hanam city failed in consensus building without satisfying the conditions of collaborative policy planning. I suggest that local governments facing conflicts of the unwanted public facilities should try set goals in policy-planning and use collaboration to make policy with outside partners for smooth implementation. I also suggest that policy leaders of local governments should listen to the vices of every stakeholder carefully first of all for the successful policy planning.

      • 정보시스템 아웃소싱 위험요인 평가 프레임�p의 개발 : 비영리 조직을 중심으로 Focusing on Nonprofit Organizations

        김창수,백명기 한국정보시스템학회 2004 情報시스템硏究 Vol.13 No.1

        As a result of the fast development of information communication technology, the competitive advantage of companies and the service quality of nonprofit organizations has been largely changed. Corresponding to this kind of change, companies have tried to make production improvement, competitive strengthening, and organizational innovation. Meanwhile, the nonprofit organizations directed by the government are pursuing the service innovation from general administration area to the public service for civilians. In relation to this, risk management of the company's information systems outsourcing has largely been studied until now. However, the study of risk management for nonprofit organization information systems outsourcing has rarely been made. In this paper, to provide the theoretical base for further research, we have attempted to develop the evaluation framework for risk management of information systems outsourcing considering the characteristics of nonprofit organizations.

      • KCI등재

        재배방식과 피복재료가 천마의 수량과 품질에 미치는 영향

        김창수,유인영,김동원,김종엽,김정만,이왕휴 한국자원식물학회 2017 한국자원식물학회지 Vol.30 No.1

        This study was compared to outdoor field (OF) and rain shelter greenhouse (RSG) according to cultivation type of Gastrodia elata Blume. Also, the effects of yield and quality for mulching materials in RSG were compared. The yield of G. elata was investigated good merchantable quality, and the quality was investigated hardness, chromaticity, weight loss and the contents of the major functional components. The cultivation of RSG was increased the yield, hardness, gastrodin, and vanillyl alcohol compared to OF, and the weight loss, chromaticity, and ergothioneine were almost equal. Rice straw treatment showed higher than those of the control and other treatments on the yield and hardness. As a result, the yield and the quality of RSG, which can control the soil moisture, were better than that of OF. And the lower the soil moisture content according to the mulching material, the harder the surface and the higher the hardness. 천마의 수량과 품질 향상을 위하여 비가림시설재배와 노지재배, 비가림시설내 여러 피복재료를 활용하여 천마의 수량 및품질에 미치는 영향을 비교분석하였다. 천마의 수량은 비가림시설이 노지재배에 비해 49% 증수되었다. 또한, 비가림시설재배내에서 피복재료 처리에 따른 천마의 수량성은 무피복에 비해 볏짚피복 44%, 낙엽피복 26%, 차광망피복에서 각각 22% 증수되었다. 천마의 증숙 전․후 색도는 비가림시설재배가 노지재배에 비해 색도 변화가 적었다. 또한, 천마의 경도는 비가림시설재배가 노지재배보다 더 높았고, 비가림시설재배의 증숙 후는 증숙 이전에 비해 17.1%, 노지재배는 29.2% 각각 감소하였다. 증숙 후 무게 감소율의 경우 비가림시설재배는 10.3%, 노지재배는 9.1% 감소하였다. 가스트로딘, 바닐린 알콜은 노지재배보다 비가림시설재배에서 함량이 증가하였고, 에르고티오닌은재배시설에 따른 변화는 없었다. 따라서 환경을 인위적으로 조절이 가능한 비가림시설재배가 노지재배에 비해 천마의 수량과품질이 좋았으며, 피복재료에 따른 품질은 토양수분함량이 낮을수록 표면이 단단해져 경도가 높아지는 경향을 보였다.

      • KCI등재

        Can Socially Responsible Investments Be Compatible with Financial Performance? A Meta-analysis

        김창수 한국증권학회 2019 Asia-Pacific Journal of Financial Studies Vol.48 No.1

        This paper examines whether socially responsible investment (SRI) outperforms conventional investments by meta-analysis. The result shows that weighted average effect size is not significantly different from zero, suggesting that SRI performance is not different from conventional investments. Meta-regression results regarding sampling issues indicate that economic crisis, control group, investment universe, screening procedure, and mutual funds are important determinants of effect sizes, and publication year, author type, and control group are important factors of the absolute value of effect sizes. Regarding methodological issues, risk adjustment, weighting scheme, data refinement, benchmark model, and matching procedure are significant factors determining the absolute value of effect sizes.

      • 특집 - 한국의 병원건축 : 삼성의료원을 설계하면서 ( Architectural Review of Samsung Medical Center )

        김창수 대한건축학회 1994 建築 Vol.38 No.11

        삼성 서울병원은 서울시 강남구, 서초구, 송파구 일대의 지역 주민들에 대한 응급 진료 및 전국을 대상으로 하는 특수질환 전문 3차 의료기관기능을 수행하며 특히 국내 최고수준의 인력, 시설, 장비를 갖춘 종합의료기관으로써 의료의 질적 수준향상을 도모하고 21세기 초일류 병원을 추구함에 그 설립 목적이 있으며, 기본운영방침으로서 간호인력의 효율화 및 전문화로 보호자가 없는 병원, 의사의 진단 및 처방의 전산화로 처방전이 없는 병원, 의학계를 선도하며 최신 의학정보가 가장 빨리 보급되는 병원, 신바람나게 근무하는 병원을 추구하고 있다.

      • KCI등재

        A Study on the Development of the (Augmented Reality) Maintenance and Repairs Related Safety Manual According to the Risk Analysis of Power Equipment

        김창수 대한설비관리학회 2022 대한설비관리학회지 Vol.27 No.4

        The complexity and safety of power facilities have increased very rapidly, yet efforts are insignificant in ensuring safety according to risks. Hence, the purpose of is, in order to help prevent safety accidents in advance, risk factors are listed through the risk analysis of power facilities, and to develop an augmented reality safety manual according to the improvement of risk scales to ensure the safety by conducting pre-simulation in the field and taking prompt response at the accident site. The bottom-up analysis of the effects of failure modes on the users and the causes of failures of components in the power facility system to which the Design Failure Mode and Effect Analysis (DFMEA) technique is applied is carried out, and at the same time, by developing the augmented reality (AR) based maintenance software based on the improvement contents according to the level of risk listing risk factors, the maintenance methodology due to the spread of infectious diseases in the era of contactless is presented. The development of augmented reality system (software) for maintenance implements the 2D and 3D facility exploded view and work manual, etc., which enable the actual work processes to be performed across various field environments according to emergency situations of power facilities, and the big data based field data, and through acquisition, it would be possible to establish a precision standard maintenance platform. Furthermore, it is expected to have the effect of reducing the costs for accident prevention and maintenance work, and increasing the quality and quantity. Through this study, the safety of electric power facilities and a preventive method in emergency situations are presented. The software development through augmented reality (AR) through the Design Failure Mode and Effect Analysis (DFMEA) can help prevent accidents and implement condition based maintenance plans in an integrated system, and hence, a high efficiency can be expected. It is considered that accuracy, reliability, and safety improvement are required in future papers through the addition of risk points and continuous development of diagnostic algorithm libraries.

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