甲狀腺炎과 Lithium 治療에 의한 甲狀腺機能低下症

鄭道彦,禹鍾仁,李定均,趙普衍,高昌舜,金勇一 大韓神經精神醫學會 1982 신경정신의학 Vol.21 No.2

A case of a female Manic Depressive Illness patient with goitrous hypothyroidism is presented. After ten and half months of lithium maintenance therapy starting during her first psychiatric admission, she was admitted again due to acute recurrent manic episode. On admission, she complained of easy fatigability and cold intolerance, and thyroid gland was palpable and enlarged in moderate degree. Thyroid function test revealed markedly increased TSH and moderately decreased thyroxine levels. TRH stimulation test showed an exaggerated response. Needle biopsy specimen revealed chronic lymphocytic and immune complex thyroiditis. However, antithyroglobulin and antimicrosomal antibodies were negative. In pretreatment thyroid evaluation on her first admission, neither goiter nor thyroid function abnormality was detectable and no signs of underlying thyroid disease or hereditary predisposition to hypothyroidism were present. Within three weeks of discontinuation of lithium, goiter was no more palpable and within five weeks, thyroid function test returned to normal range. The possibility that patients with underlying thyroiditis may be particularly susceptible to a rapid onset of lithium-induced hypothyroidism is discussed.

사망재해 분석을 통해 본 사업장 응급의료실태 조사

신상도,김정연,김정순 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.4

목적 : 본 연구는 마산, 창원, 거제에 있는 8개 사업장을 대상으로 사업장 응급의료의 현황을 조사하고 최근 4년간 발생한 25례의 사망재해를 분석하여 병 원전단계 응급의료체계의 실태와 문제점을 파악하고자 고안되 었다. 방 법 : 사업장 일반현황에 대한 조사와 사업장 응급의료체계의 실태를 조사하기 위하여 해당 사업장의 안전관리자 및 노동조합의 산업안전부서 담당자에 대한 면접조사를 시행하였으며 사망재해 발생 현황과 사망재해에 대응한 응급의료 실태 분석을 위하여 재해보고서, 사업장 내 의무실 기록, 응급센터의 의무기록을 조사하였다. 결 과 : 8개 사업장의 전체 노동자 수는 1999년 기준으로 26,803명 이었으며 각 사업장에는 작업공정에 특수한 위험 기기 및 공정, 위험 인화 및 폭발물질, 위험 고공 작업 공정이 있었다. 3개의 사업장에 상주 의사가 근무하고 있었으며 나머지 사업장에는 간호사 및 보건직 인력이 상주하고 있었다. 3개의 사업장에서 안전관련 교육을 연간 24시간 시행하였으나 나머지는 연간 8시간 이하의 교육을 시행하였다. 모든 사업장에는 의무실을 갖추고 있었으며 3개의 사업장은 구급차를 보유하고 있었다. 구급차의 동원에 필요한 시간은 6개 사업장에서 5∼10분, 2개 사업장에서 10∼30분이 소요된다고 하였다. 또한 응급센터로의 후송은 30분 이내에 모두 가능하였다. 그러나 모든 사업장이 기도유지 장비나 쇽 처치 장비는 보유하고 있지 않았다. 25례의 사망재해 중 1개 사업장에서 15례가 발생하였으며 4개의 사업장에서는 사망재해가 발생하지 않았다. 사망재해의 경력별 분포에서 10년 이상인 경우가 64 %에 달하였고 68 %의 사례는 낙하, 충돌, 추락 등 재래형 사망재해 유형에 해당하였다. 사망재해시 1차 구조는 대부분 사내외 소방서에 의뢰하였으며 구급차의 동원은 87 %가 10분 이상을 소요하였다. 사망재해 중 48 %에서는 현장내 응급 처치가 전혀 시행되지 않았으며 응급센터로의 후송 시간 역시 50 %에서 30분 이상을 필요로 하였다. 사망시간은 재해 이후 1시간 이내가 40 %, 1∼4시간이 50 %를 차지하였으며 사망원인에서는 68 %가 두경부 및 흥부 손상에 의한 사망이었다. 결 론 : 본 연구를 통하여 파악된 사업장 응급의료 체계의 문제점은 첫째 일반노동자에 대한 재해관련 교육의 부족 둘째, 응급의료 인력에 대한 지식 및 기술의 부족, 전문인력의 상주 및 배치의 부족 셋째, 중증재해에 대비할 수 있는 응급의료 장비의 부족 넷째, 응급센터로의 신속한 후송에 필요한 인적 물적 자원의 부족 등이다. 이를 바탕으로 사업장에 특 이적인 병 원전단계 응급의료체계의 구축을 위하여 보다 세부적인 연구가 필요하다고 사료된다. Objectives : This study was designed to evaluate the problems of pre-hospital Emergency medical care system (EMS) in workplace. We analysed 25 fatal work-place injuries during the recent 4 years and the work-place EMS of 8 enterprises located in Masan-city, Changwon-city and Kuje-island. Methods : The safety managers and the members of Dept. of safety in the labor unions were interviewed about the work-place EMS. And we investigated on the injury reports, the work-place medical-room records and the medical records of emergency center for fatal 25 cases. Results : The enterprises had the at-risk machines and processes, volatile materials and high-altitude working processes. There were duty doctors in only 3 enterprises but a few duty nurses or health-care providers in the others. The time spent for the education to the workers on safety was 24hrs/yr in 3 enterprises in 1998 but less than Bhrs in the others. There were medical service center in all enterprises but the ambulances in three. The time for activation of the ambulance was ranging from 5 minutes to 10 minutes in 6 enterprises, and from 10 minutes to 30 minutes in two. The patient transportation to the emergency center was possible within 30 minutes in all enterprises but there were no equipments for airway maintenance and shock management in all enterprises. The 15 (60%) fatal injuries were occurred at one enterprise. The 64% of casualties had the duration of job-employment more than 10yrs and the 68% were suffered the typical type of work-place injury as descending injuries, collisions and falls. Most of all primary calls for rescue were concentrated on the fire-service agencies. But in 85% of fatal injtories, the tome for the activation of ambulance was more than 10 minutes and no emergency care was taken in the field in 48 percent of casualtles. The transportation time to the emergency center was more than 30 minutes in 50 percent. It toolk from injury to death was less than one hour in the 40 percent of all cases, and from one hour to four in the 50 percent. The causes of death in the 68 percent were the head-and-neck injuries or thoracic injuries. Conclusions : We found that there was Insufficiency of the education associated with work-place injury for workers, manpower and facilities, equipments related to the work-place EMS, the problems of the delay in transportation system.

슬관절 골관절염 증상이 환자에게 미치는 우울 효과

박영규,이윤영,이계우,김정아,윤도경,박승회,조경환,홍명호,박용규 대한노인병학회 2001 대한노인병학회지 Vol.5 No.4

슬관절 골관절염 환자에서 근육내 자극요법의 치료 효과

박영규,우종웅,안승렬,김정아,윤도경,박승회,조경환,홍명호 대한노인병학회 2001 대한노인병학회지 Vol.5 No.4

Characterization of Bacillus subtilis SCGB634 containing Potential Probiotic Properties and Antimicrobial Activity against Foodborne Pathogenic Bacteria

Jeong Seon Eom,Myeong Seon Ryu,Hee-Jong Yang,Su-Ji Jeong,Su-Jin Shin,Jin Kyeong Kim,Seong-Yeop Jeong,Do-Youn Jeong 한국식품영양과학회 2016 한국식품영양과학회 학술대회발표집 Vol.2016 No.10

Isolation and Characterization of Biogenic Amines Non-producing Bacillus subtilis SCGB159 having Antibacterial Activity against Foodborne Pathogenic Bacteria

Jeong Seon Eom,Myeong Seon Ryu,Hee-Jong Yang,Su-Ji Jeong,Su-Jin Shin,Jin Kyeong Kim,Seong-Yeop Jeong,Do-Youn Jeong 한국식품영양과학회 2016 한국식품영양과학회 학술대회발표집 Vol.2016 No.10

Notes : Screening and Characterization of Secretion Signals from Lactococcus lactis ssp. cremoris LM0230

( Do Won Jeong ),( Youn Chul Choi ),( Jung Min Lee ),( Jung Min Seo ),( Jeong Hwan Kim ),( Jong Hoon Lee ),( Kyoung Heon Kim ),( Hyong Joo Lee ) 한국미생물 · 생명공학회 2004 Journal of microbiology and biotechnology Vol.14 No.5

Photobiological (LED light)-mediated fermentation of blueberry (<i>Vaccinium corymbosum</i> L.) fruit with probiotic bacteria to yield bioactive compounds

Jeong, Seong-Yeop,Velmurugan, Palanivel,Lim, Jeong-Muk,Oh, Byung-Taek,Jeong, Do-Youn Elsevier 2018 FOOD SCIENCE AND TECHNOLOGY -ZURICH- Vol.93 No.-

<P>The aim of this study was to investigate if fermentation of blueberry fruit by Bacillus amyloliquefaciens and Lactobacillus brevis under green, red, blue, and white light emitting diode (LED) illumination or sunlight could yield functionalized products for biomedical applications. Fermentation by both bacterial species under white and green LED light and sunlight resulted in increased viable cell count of the bacteria as well as total phenol and flavonoid contents over 72 h of fermentation. Blue and red LED light fermentation and that in darkness resulted in fermented samples with moderate anti-bacterial activity based on minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) as well as antioxidant and cytotoxic assays compared to fermentations under other light sources. In addition, Fourier transform infrared spectroscopy (FT-IR) was performed to determine the functional groups in the non-fermented (control) and fermented products. Sunlight and white, red, and green LED light-fermented extracts contained alcohol, acid, and phenol groups, as well as aliphatic amines. The results of this study clearly indicate that fermentation of blueberries with probiotic bacteria under various LED light sources can yield compounds that can be used in cosmetic and value-added food products.</P>

잠재적 생균제로서 식물 젖산균의 분리 및 특성

김정도 ( Jeong Do Kim ),박성보 ( Sung Bo Park ),이나리 ( Na Ri Lee ),정진하 ( Jin Ha Jeong ),이희섭 ( Hee Seob Lee ),황대연 ( Dae Youn Hwang ),이종섭 ( Jong Sup Lee ),정성윤 ( Seong Yun Jeong ),손홍주 ( Hong Joo Son ) 한국미생물생명공학회(구 한국산업미생물학회) 2011 한국미생물·생명공학회지 Vol.39 No.3

Plant lactic acid bacteria were isolated from plant-associated fermentative foods and crops, and their probiotic properties were investigated. Isolates K27 and O2 were isolated from Kimchi and onion, and identified as Lactobacillus plantarum on the basis of 16S rRNA gene analysis. The two strains were highly resistant to acid (an MRS broth at pH 2.5), where the survival rates of L. plantarum K27 and L. plantarum O2 were 90.2% and 97.3%, respectively. L. plantarum K27 and L. plantarum O2 also showed high bile resistance to 0.5% oxgall, with a more than 70% survival rate. They showed an inhibitory effect against pathogenic strains of Escherichia coli KCCM 40880 and Pseudomonas aeruginosa ATCC 10145. The antibacterial effect of the two strains was probably due to the presence of lactic acid. ACE inhibitory activities of the two strains ranged from 72.8% to 80.6% in MRS broth. Notably, the two strains showed high ACE inhibitory activity (89.2~98.2%) in MRS broth containing 10% skim milk. Antioxidant activity was tested by DPPH radical scavenging activity, with antioxidant activities of the strains being in the range of 56.8~61.5%. The results obtained in this study suggest that L. plantarum K27 and L. plantarum O2 may be potential probiotic starter cultures with applications with fermentative products.

창업기업 CEO의 윤리적 리더십과 변혁적 리더십이 조직성과에 미치는 영향연구

정도윤(Do-Youn Jeong),서영욱(Young-Wook Seo) 한국산학기술학회 2022 한국산학기술학회논문지 Vol.23 No.4

경쟁이 심화되고 있는 시장환경에서 창업기업의 성장과 발전에 지대한 영향을 미치는 CEO 리더십 관련 연구의 필요성 요구되고 있다. 본 연구는 창업기업 CEO의 윤리적 리더십(사람지향성, 공정성, 책임)이 윤리적 문화를 통해서 조직성과에 미치는 영향을 살펴보고, CEO의 변혁적 리더십이 기업혁신을 통해서 조직성과에 미치는 영향을 살펴봄으로써 CEO의 리더십 유형에 따른 조직성과를 분석하였다. 본 연구는 1년이상 재직중인 임직원을 대상으로 설문 조사된 2년이상 7년 미만의 업력을 가진 총 410개의 기업을 대상으로 Smart PLS 3.0을 사용하여 통계분석을 진행하였다. 본 연구에 따르면, CEO의 윤리적 리더십(사람지향성, 공정성, 책임) 및 변혁적 리더십은 각각 윤리적 문화 및 기업혁신에 긍정적 영향을 주는 것으로 나타났다. 그리고 윤리적 문화 및 기업혁신은 기업성과에 긍정적 영향을 주는 것으로 나타났다. In a market environment where competition is intensifying, there is a need for research on CEO leadership, which has a profound effect on the growth and development of start-ups. This study examined the effect of the entrepreneurial CEO"s ethical leadership (people-orientation, fairness, and responsibility) on organizational performance through ethical culture and also examined the effect of the CEO"s transformational leadership on organizational performance through firm innovation. The organizational performance was analyzed according to the CEO"s leadership type. Statistical analysis was conducted using Smart PLS 3.0 for 410 companies with more than 2 years and less than 7 years of work experience surveyed by employees who had been in service for more than 1 year. According to this study, CEO"s ethical leadership (people-orientation, fairness, and responsibility) and transformational leadership had a positive effect on ethical culture and corporate innovation, respectively. Ethical culture and corporate innovation had a positive effect on corporate performance.