규칙적인 운동습관이 고혈압 환자의 24시간 활동혈압에 미치는 영향

최승욱(Choi, Seung-Wook) 한국체육과학회 2012 한국체육과학회지 Vol.21 No.3

The purpose of this study of changes in 24-hour ambulatory blood pressure by exercise habits and make comparative analysis of 24-hour ambulatory blood pressure (systolic and diastolic pressure), the mean arterial pressure, the heart rate, and DP according to measuring time and activity types in hypertension patients in order to provide basic data for systematic and scientific exercise prescription. 24-hour ambulatory blood pressure was measured by TM2430 (A&D, Japan) automatically every 30 minutes from 07:00 a.m. to 10:00 p.m. for daytime blood pressure and every one hour from 10:00 p.m. to 07:00 a.m. the next day for nighttime blood pressure. The results was as follow: 1) As for differences in daytime and nighttime, the exercise habit group showed the significantly lower systolic blood pressure(p<.001), heart rate(p<.001) and DP(p<.001) in the daytime and significantly lower systolic blood pressure(p<.05), heart rate(p<.05) and DP(p<.001) in the nighttime. 2) As for differences in activity type, the exercise habit group showed the significantly lower systolic blood pressure(p<.05) and mean arterial pressure(p<.05) in the commuting time and significantly lower systolic blood pressure(p<.05) in the talking time.

운동습관에 따른 시간대별 24시간 활동혈압, 평균동맥압, 심박수 및 Double Product 비교 연구

안지희(An Ji-Hee),최성근(Choi Sung-Gun),최승욱(Choi Seung-Wook) 한국체육과학회 2009 한국체육과학회지 Vol.18 No.4

The purpose of this study is to examine frequency (%) of occurrence of borderline hypertension through changes in 24-hour ambulatory blood pressure by exercise habits and make comparative analysis of 24-hour ambulatory blood pressure (systolic and diastolic pressure), the mean arterial pressure, the heart rate, and DP by time slots in middle-aged staff of 40 years old and over belonging to the normal blood pressure group in order to provide basic data for systematic and scientific exercise prescription. 24-hour ambulatory blood pressure was measured by TM2430 (A&D, Japan) automatically every 30 minutes from 07:00 a.m. to 10:00 p.m. for daytime blood pressure and every one hour from 10:00 p.m. to 07:00 a.m. the next day for nighttime blood pressure. The results was as follow: 1) As for differences in 24-hour time by exercise habits, the exercise habit group showed the significantly lower heart rate in 22:00 p.m, 01:00 a.m and significantly lower DP in 01:00 a.m. 2) As for differences in daytime and nighttime by exercise habits, the exercise habit group showed the significantly lower heart rate and DP in the daytime and significantly lower ambulatory blood pressure and DP in the nighttime. 3) As for differences in frequency (%) of occurrence of borderline hypertension by exercise habits, there was no significant difference; the exercise habit group was at the lower level than the non-exercise habit group, with both showing over 15%.

경계성 고혈압 중년 남성의 24시간 활동혈압 변화에 관한 연구

안지희(An Ji-Hee),이재문(Lee Jae-Moon),최승욱(Choi Seung-Wook) 한국체육과학회 2010 한국체육과학회지 Vol.19 No.1

The purpose of this study of changes in 24-hour ambulatory blood pressure by exercise habits and make comparative analysis of 24-hour ambulatory blood pressure (systolic and diastolic pressure), the mean arterial pressure, the heart rate, and DP according to measuring time and activity types in middle-aged men over belonging to the prehypertensive group in order to provide basic data for systematic and scientific exercise prescription. 24-hour ambulatory blood pressure was measured by TM2430 (A&D, Japan) automatically every 30 minutes from 07:00 a.m. to 10:00 p.m. for daytime blood pressure and every one hour from 10:00 p.m. to 07:00 a.m. the next day for nighttime blood pressure. The results was as follow: 1) As for differences in daytime and nighttime, the exercise habit group showed the significantly lower heart rate and DP in the daytime and significantly lower ambulatory blood pressure, the mean arterial pressure, the heart rate, and DP in the nighttime. 2) As for differences in activity type, the exercise habit group showed the significantly lower heart rate in the talking time and significantly lower DP in the sleeping time.

太白(SP3)․太谿(KI3)瀉法 刺鍼이 白鼠의 국소뇌혈류량 및 평균 동맥압에 미치는 영향

천혜선,조명래,류충열 대한침구의학회 2010 대한침구의학회지 Vol.27 No.3

Experimental Study of Taegye(KI3) Taebaek(SP3) Draining Acupuncture on the Improvement of Cerebral Blood flow and Arterial Blood Pressure. Objectives : This study was designed to investigate the effects of acupuncture on Taegye(KI3) Taebaek(SP3) draining and determine the mechanism of action of PCBL by measuring the changes of regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats. Methods : This study was designed to investigate whether acupuncture on Taegye(KI3)․Taebaek(SP3) draining affect Regional cerebral blood flow(rCBF), Mean arterial blood pressure(MABP) in normal rats. To make manifest whether acupuncture on Taegye(KI3)․Taebaek(SP3) draining was mediated by inhibitor of cyclooxygenase or guanylate cyclase which diate arterial diameter. Results 1. Acupuncture on Taegye(KI3)․Taebaek(SP3) draining significantly increased rCBF but decreased MABP. This result suggests that Acupuncturing on Taegye(KI3)․Taebaek(SP3) draining might significantly increase rCBF by dilating arterial diameter. 2. Acupuncture on Taegye(KI3)․Taebaek(SP3) draining induced increase of rCBF was significantly inhibited by pretreatment with indomethacin (1 ㎎/㎏, i.p.), an inhibitor of cyclooxygenase. 3. This result suggests that the action of Acupuncture on Taegye(KI3)․Taebaek(SP3) draining might be mediated by cyclooxygenase.

침엽수종 유래 정유가 진통 및 순환기계에 미치는 영향

나기정,정의배 한국임상수의학회 1999 한국임상수의학회지 Vol.16 No.2

The influence of essential oils from aboriginal softwoods as Pinus densiflora, Pinus koraiensis, Chamaecyparis obtusa and Chamaecyparis pisifera on the motor coordination, pulse, mean blood artery pressure and pain reducing test was investigated in mice and rats. The motor coordination of mouse was not induced by the inhalation of each oil. Furthermore, these oils did not alter the changes of the mean blood pressure and pulse rate. Chamaecyparis pisifera trand to reduce the mean blood pressure. The abdominal pain induced by acetic acid was reduced only by an essential oil from Pinus koraiensis in mouse.

유도와 저항성 운동이 경찰학과 여학생들의 심혈관 및 혈관내피세포 기능에 미치는 영향

장용우 한국경호경비학회 2023 시큐리티연구 Vol.- No.76

본 연구의 목적은 16주간의 유도와 저항성 운동이 심혈관 및 혈관내피세포 기능에 미치 는 영향을 분석하는 것이다. 대상자들은 실험군 10명, 통제군 10명으로 분류하였다. 심혈관 기능 검사는 수은혈압계를 이용하여 혈압을 측정하였으며, Physioflow를 이용한 심박수, 1회 박출량, 심박출량, 평균동맥압을 측정하였다. 혈관내피세포 기능 검사는 Pulse wave Doppler를 이용하여 안정시 혈관직경, 안정시 혈류량, 최대혈관직경, 최대혈류량을 0주와 16주 측정 분석하였다. 유도와 저항성 운동의 시기별 심혈관 기능의 통제군의 변화는 없었 다. 실험군의 심박수(-8.53%), 1회 박출량(5.84%), 심박출량(9.30%)은 유의한 차(p<.05, p<.01, p<.001)가 나타났으며, 실험군의 수축기 및 이완기혈압의 경우 통계적인 변화는 없 었다. 실험군의 평균동맥압(-6.77%)은 유의하게(p<.01) 감소 수준을 유지하여 개선된 심혈 관 기능의 변화를 관찰할 수 있었다. 혈관내피세포 기능의 경우 통제군은 각 시기 별 유의 한 변화는 나타나지 않았다. 실험군의 경우 안정시 혈관직경(-2.68%)은 통계적인 유의수준 은 없었으며, 안정시 혈류량(128.6%), 최대혈류량(12.8%)은 유의하게(p<.05, p<.01) 높게 나 타났다. 혈관의 수축과 확장치를 예측할 수 있는 최대혈관직경(-4.36)의 경우 유의하게 (p<.05) 낮은 감소 수준을 나타냈으며, 혈관 확장기능의 개선 정도를 알 수 있는 %FMD (22.8%)는 유의하게(p<.001) 높은 증가를 나타냄으로서 혈관내피세포의 기능적 개선 정도 를 살펴볼 수 있었다. 따라서 본 연구의 16주간의 주 4회 유도와 저항성 운동은 경찰전공 지망생들의 혈관계의 기능적 개선을 통해 추후 여학생들의 경찰임용을 대비한 효율적인 복합운동프로그램으로 권장하고자 한다. The purpose of this study was to analyze the effects of 16 weeks of induction and resistance exercise on cardiovascular and vascular endothelial function. The subjects were divided into 10 experimental groups and 10 control groups. For cardiovascular function tests, blood pressure was measured using a mercury sphygmomanometer, and heart rate, stroke volume, cardiac output, and mean arterial pressure were measured using Physioflow. For vascular endothelial cell function test, pulse wave Doppler was used to measure and analyze resting vessel diameter, resting blood flow, maximum vessel diameter, and maximum blood flow at 0 and 16 weeks. There was no change in cardiovascular function in the control group by period of induction and resistance exercise. There were significant differences (p<.05, p<.01, p<.001) in the heart rate (-8.53%), stroke volume (5.84%), and cardiac output (9.30%) of the experimental group. There was no statistical change in systolic and diastolic blood pressure. The mean arterial pressure (-6.77%) of the experimental group maintained a significant (p<.01) decrease level, and improved cardiovascular function could be observed. In the case of vascular endothelial cell function, the control group did not show significant changes at each time period. In the experimental group, there was no statistically significant level of blood vessel diameter at rest (-2.68%), and blood flow at rest (128.6%) and maximum blood flow (12.8%) were significantly (p<.05, p<.01) high. appear. The maximum vascular diameter (-4.36), which can predict the contraction and dilation of blood vessels, showed a significantly (p<.05) low level of decrease, and %FMD (22.8%), which can determine the degree of improvement in vasodilation function, By showing a significant (p<.001) high increase, it was possible to examine the degree of functional improvement of vascular endothelial cells. Therefore, induction and resistance exercise 4 times a week for 16 weeks in this study is recommended as an effective combined exercise program in preparation for female police officers in the future through functional improvement of the vascular system of aspiring police majors.

37권6호 영문부록 : 프로포폴/아산화 질소 마취에 있어 펜타닐의 지속적 정주가 프로포폴의 요구량, 마취에서의 회복 및 수술 후 진통효과에 미치는 영향

한태형(Tae Hyung Han),강형만(Hyun Man Kang),길호영(Ho Yeong Kil) 대한마취과학회 1999 연수강좌 Vol.- No.-

Background : It is very important to understand the drug interaction in total intravenous anesthesia. We conducted this study to find the effects of plasma fentabyl concentrations on intraoperative propofol requirements, emergence from anesthesia and relief of postoperative pain. Methods : Total 60, ASA physical status I-II patients who underwent spine fusion were studied. The patients were randomly assigned to four study groups according to the expected intraoperative plasma fentanyl concentration. Group I received an infusion of saline and Groups II, III and IV received fentanyl infusions to maintain the blood level at 1.5, 3.0 and 4.5 ng/ml, respectively. An infusion rate of propofol was adjusted to keep the mean arterial pressure (MAP) within 15% of the control value. Inspired nitrous oxide concentration was maintained at 67% throughout the surgical procedure. The following items were investigated in each group: 1) an average propofol infusion rate, 2) time to spontaneous eye opening and recovery of orientation (name, date and place) and 3) total dosage of fentanyl used for 24 hr after admission to post-anesthetic care unit. Results : Average propofol infusion rates were 10.1±2.5 (mean±SD), 7.5±1.2, 5.7±1.1, and 4.9±1.2 mg/kg/h, in Group I, II, III and IV, respectively. Groups receiving fentanyl infusion had significantly less administration rates (P< 0.01) than the group receiving saline infusion. Among the three fentanyl infusion groups, Group II (P< 0.01) had more than Groups III and IV. Time to spontaneous eye opening and the recovery of orientation were prolonged in the order of plasma fentanyl concentration. There was no significant difference between Groupss III and IV of the plasma fentanyl level of 3 and 4.5 ng/ml. Total amount of IV-PCA fentanyl during postop 24 h increased significantly in the reversed order of plasma fentanyl concentrations: 913.1±58.4, 553.4± 129, 222.7±73.4 and 135.1±69.5 mcg in Groups I, II, III and IV, respectively. Conclusion : These results confirmed that the addition of fentanyl infusion had analgesic ceiling effects, which in turn reduced the average propofol infusion rate to plasma fentanyl concentration level of 3 4.5 ng/ml. This had an indirect influence on the recovery of consciousness after surgery, but it did not show similar ceiling effect in postoperative analgesia. (Korean J Anesthesiol 1999; 37: S 1∼S 9)

성인둔상환자에서 평균동맥압과 위해사건발생의 관련성: 단면 조사 연구

차승용 ( Seung Yong Cha ),김용환 ( Yong Hwan Kim ),홍종근 ( Chong Kun Hong ),이준호 ( Jun Ho Lee ),조광원 ( Kwang Won Cho ),황성연 ( Seong Youn Hwang ),이경렬 ( Kyoung Yul Lee ),이영환 ( Young Hwan Lee ),최성희 ( Seong Hee Choi 대한외상학회 2013 大韓外傷學會誌 Vol.26 No.2

Purpose: Non-invasive blood pressure measurement is widely used as a pre-hospital triage tool for blunt trauma patients. However, scant data exits for using the mean arterial pressure (MAP), compared to the systolic blood pressure, as a guiding index. The aim of this study was to determine the association between adverse outcomes and mean arterial pressure (MAP) and to exhibit the therapeutic range of the MAP in adult blunt trauma patients. Methods: The electronic medical records for all trauma patients in a single hospital from January 2010 to September 2012 were retrospectively reviewed. Patients below 17 years of age, patients with penetrating injuries, and patients with serious head trauma (injuries containing any skull fractures or any intracranial hemorrhages) were excluded. Adverse outcomes were defined as one of the following: death in the Emergency Department (ED), admission via operating theater, admission to the intensive care unit, transfer to another hospital for emergency surgery, or discharge as hopeless. Results: There were 14,537 patients who met entry criteria. Adverse outcomes occurred for MAPs in range from 90 to 120 mmHg. Adverse outcomes were found, after adjusting for confounding variables, to occur increasingly as the MAP declined below 90 mmHg or rose above 120 mmHg. Conclusion: Not only lower but also higher mean arterial pressure is associated with increased adverse outcomes in adult blunt trauma patients. Thus, patients with a MAP above 120 mmHg should be considered as a special group requiring higher medical attention, just as those with a MAP below 90 mmHg are.

fficacy of mean arterial pressure, intracranial pressure, and cerebral perfusion pressure for prediction of neurological prognosis and mortality in cardiac arrest survivors who underwent target temperature management

손승하,박정수,유연호,민진홍,안홍준 대한응급의학회 2018 대한응급의학회 학술대회초록집 Vol.2018 No.2

악교정 수술시 유도저혈압 마취를 위해 사용되는 Esmolol과 Nitroglycerin의 효과에 대한 비교 연구

정영수(Young Soo Jeong),강정완(Jeong Wan Kang),박형식(Hyung Sik Park),이충국(Choong Kook Yi),이의웅,(Eui Woong Lee) 대한구강악안면외과학회 1998 대한구강악안면외과학회지 Vol.24 No.4

Induced hypotension is used to help control bleeding during procedures where surgical hemostasis is technically difficult to achieve. A mean arterial blood pressure(MABP) as low as 50-60 mmHg appears to be well tolerable in healthy patients. The present study was designed to compare the efficacy of Esmolol and Nitroglycerin as primary drug for hypotensive anesthesia during 22 cases of orthognathic surgery, and compare their effects on blood loss, duration of surgery, quality of the surgical field, hormonal response, and patient outcome. The results obtained are as follows. 1. During the induced hypotension, mean arterial blood pressure was similarly reduced in esmolol group and nitroglycerin group. And any significant difference was not seen in the time of inducing hypotension from starting the drug administration, preoperative mean blood pressure and mean blood pressure during the period of postoperative recovery. 2. Difficulty of the operation, quality of the surgical field and total operation time in 2 groups show no difference but the time during hypotension was significantly reduced in esmolol group. 3. Urine output, administered fluid volume, transfusion volume of autologous blood, preoperative and postoperative base excess, preoperative and postoperative hematocrit had no difference between 2 groups. 4. The change of the plasma renin activity was more lowered in esmolol group than in nitroglycerin group. Based on the above results, esmolol can replace the nitroglycerin as a new primary drug for hypotensive anesthesia. Especially, esmolol is more recommendable than nitroglycerin on the effect of stability in renin-angiotensin system and prevent rebound hypertension in posthypotensive period.