A case of solitary sclerotic fibroma

( Hyunjung Kwon ),( Hyungrok Kim ),( Youngil Kim ),( Inyong Kim ),( Kyungduck Park ),( Joonsoo Park ),( Hyun Chung ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1

Sclerotic fibroma is one of the uncommon histologic variants of soft fibroma, and can be seen either as a solitary nodule or multiple nodules in association with disorders such as Cowden’s disease (multiple hamartoma syndrome). Clinically, the lesions usually present as asymptomatic, flesh-colored, waxy papules on any part of the skin. Histopathologically, the lesion is characterized by a well-defined dermal fibroma of unusual, peculiar, and hyalinized collagen bundles with hypocellularity. A 19-year-old man presented with a solitary bean sized protruding nodule on scalp. The lesion has been growing slowly for 2 years. He had no medical history, and there was no family history of skin diseases. Physical examination revealed a l.5cm-sized, erythematous, dome-shaped solitary nodule on his left parietal scalp. Simple excision was done and the biopsy specimen showed a well-defined, non-encapsulated, sharply demarcated dermal nodule. It was comprised with hyalinized thick bands of collagen with prominent clefts. Based on these clinical and histopathologic features, the patient was diagnosed with solitary sclerotic fibroma. Herein, we report a rare case of a solitary sclerotic fibroma.

A case of oral fibroma

( Hoo Min Choi ),( Sung Min Kim ),( Jae Won Kang ),( Byung In Ro ),( Han Kyoung Cho ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

Oral fibroma is a tumor-like mass of fibrous scar tissue caused by chronic trauma, typically a bite injury. It is also known as traumatic fibroma or irritation fibroma. The patient notices a painless (unless recently bitten) nodule that is located at sites easily bitten, such as the lower labial mucosa, lateral tongue, and buccal mucosa. It will be suspected clinically when it presents with the usual history and examination findings. Other differential diagnosis such as lipoma, oral papilloma, granular cell tumor, salivary gland tumor, mucocele, etc. should have to be considered. Histology shows typical dense fibrous tissue and overlying epithelium may be ulcerated, thinned or thickened. Surgical excision is only option of treatment. A 34-year-old man presented with dome shaped pinkish firm nodule on lower lip. The lesion was a 0.7x0.5 cm sized and its onset was 1 year ago. Punch biopsy specimen showed acanthosis, rete ridge elongation and proliferation of collagen fiber and fibroblasts in the dermis. We diagnosed it as oral fibroma and consulted to department of otorhinolaryngology for surgical excision.

Three types of ossifying fibroma: A report of 4 cases with an analysis of CBCT features

Jih, Myeong Kwan,Kim, Jin Soo Korean Academy of Oral and Maxillofacial Radiology 2020 Imaging Science in Dentistry Vol.50 No.1

Ossifying fibroma is a slow-growing benign neoplasm that occurs most often in the jaws, especially the mandible. The tumor is composed of bone that develops within fibrous connective tissue. Some ossifying fibromas consist of cementum-like calcifications, while others contain only bony material; however, a mixture of these calcification types is commonly seen in a single lesion. Of the craniofacial bones, the mandible is the most commonly involved site, with the lesion typically inferior to the premolars and molars. Ossifying fibroma of the jaw shows a female predominance. Some reports of ossifying fibroma have been published in the literature; however, this report continues the research on this topic by detailing 3 types of ossifying fibroma findings on panoramic radiographs and cone-beam computed tomographic images of 4 patients. The radiographs of the presented cases could help clinicians understand the variations in the radiographic appearance of this lesion.

Three types of ossifying fibroma: A report of 4 cases with an analysis of CBCT features

지명관,김진수 대한영상치의학회 2020 Imaging Science in Dentistry Vol.50 No.1

Ossifying fibroma is a slow-growing benign neoplasm that occurs most often in the jaws, especially the mandible. The tumor is composed of bone that develops within fibrous connective tissue. Some ossifying fibromas consist of cementum-like calcifications, while others contain only bony material; however, a mixture of these calcification types is commonly seen in a single lesion. Of the craniofacial bones, the mandible is the most commonly involved site, with the lesion typically inferior to the premolars and molars. Ossifying fibroma of the jaw shows a female predominance. Some reports of ossifying fibroma have been published in the literature; however, this report continues the research on this topic by detailing 3 types of ossifying fibroma findings on panoramic radiographs and cone-beam computed tomographic images of 4 patients. The radiographs of the presented cases could help clinicians understand the variations in the radiographic appearance of this lesion.

A case of solitary sclerotic fibroma arising in patient with mycosis fungoides

( Myung Jin Park ),( Minkee Park ),( Mi Soo Choi ),( Chan Hee Nam ),( Seung Phil Hong ),( Byung Cheol Park ),( Myung Hwa Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Sclerotic fibroma, also known as storiform collagenoma, is an uncommon fibrotic neoplasm. Clinically, the lesions usually present as asymptomatic, flesh-colored, white or translucent, waxy papules on any part of the skin of the whole body. Histologically, it shows a well-circumscribed dermal nodule with rather distinct hyalinized collagen bundles arranged in a whorled pattern. Most cases are solitary proliferating lesions and found incidentally, but sometimes sclerotic fibroma-like change has been described associated with various lesions such as melanocytic nevi, dermatofibromas, lipomas, neurofibromas, chronic folliculitis as a reactive process. A 54-year-old female who was diagnosed as mycosis fungoides 2 years ago presented with asymptomatic crusted protruding 1.5cm sized solitary nodule on Lt. leg of 4 years’ duration. She had been treated mycosis fungoides with chemotherapy, acitretin medication and narrow band UVB phototherapy.Histopathologic examination of leg nodule showed a well-defined, nonencapsulated and sharply demarcated dermal hypocellular nodule comprising hyalinized thick bands of collagen arranged in a storiform pattern. Based on these characteristic clinical findings and histopathologic features, the patient was diagnosed with solitary sclerotic fibroma. Herein, we report a case of solitary sclerotic fibroma which occurs in patient of mycosis fungoides.

경화성 섬유종과 유사한 조직 소견을 보인 피부 섬유종 2예

최윤진 ( Yoon Jin Choi ),구본철 ( Bon Cheol Goo ),정진영 ( Jin Young Jung ),정혜진 ( Hye Jin Chung ),정기양 ( Kee Yang Chung ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.6

Sclerotic fibroma is often regarded as a unique proliferating lesion, but some authors regard it as an end stage of other neoplasms, especially dermatofibroma. We report two cases of dermatofibroma with sclerotic fibroma-like change. The skin biopsy specimens from different patients showed a common finding of dermatofibroma, while some portions of the tumor were replaced by thick, hyalinized, eosinophilic collagen bundles and empty clefts with low cellularity, which was histologically similar to sclerotic fibroma. According to these findings, dermatofibroma with sclerotic fibroma-like change can be evidence of the possible pathogenesis of sclerotic fibroma. (Korean J Dermatol 2007;45(6):581∼584)

백악질 골화성 섬유종의 치과적 접근 : 증례보고 A CASE REPORT

한지혜,김재곤,백병주,양연미,이선영 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.2

백악질 골화성 섬유종은 가장 흔히 발생하는 섬유 골성 병소(fibro-osseous lesion)로서, 경계가 분명하고, 느리게 성장하는 팽창성의 양성종양이다. 임상적으로 하악골의 소구치와 대구치 부위에서 발생하고, 여성에게서 2배 정도 호발하며, 주로20대에서 30대 사이에서 발견된다. 백악질 골화성 섬유종은 섬유성 이형성증을 포함한 다른 섬유 골성 병소와 감별되어야 한다 백악질 골화성 섬유종의 또 다른 형태인 유년형 골화성 섬유종은 15세 이하에서 발생하며 빠르게 성장하고, 좀 더 골 파괴적인 양상을 보인다. 치료는 병소의 크기에 따른 절제술이고, 재발은 드물다고 알려져 있다. 본 증례는 우측 하악 견치의 미맹술을 주소로 내원한 12세 남자 어린이로, 백악질 골화성 섬유종으로 진단 후, 외과적 적출술을 시행하여 양호한 치유과정을 보이기에 보고하는 바이다. Cemento-ossifying fibroma of the jaws is well circumscribed, generally slow-growing, benign lesions which en-large in an expansile manner. Clinically, it presents as a slowly enlarging lesion commonly in the premolar-molar area of the mandible and only occasionally in the maxilla and other locations. It occurs twice as often in females and primarily in the 20 to 30 year age group. Differential diagnosis should be performed, preferably with other fibro-osseous lesions such as fibrous dysplasia. A faster growing and more destructive variant of cemento-ossifying fibroma sometimes occurs in patients under age 15 and is termed juvenile (aggressive) ossifying fibroma. Treatment is surgical removal with the extent depending on the size and location of the individual lesion. Recurrence is considered rare. A case involving a 12-year-old male patient with delayed eruption of right mandibular canine is discussed. Following an incisional biopsy, the histopathologic diagnosis established was cemento-ossifying fibroma. After the surgical enucleation of the lesion, no sign of recurrence was detected.

Central odontogenic fibroma: a case report

나경수 대한구강악안면방사선학회 2011 Imaging Science in Dentistry Vol.41 No.2

Central odontogenic fibroma is a rare odontogenic neoplasm that originates from odontogenic ectomesenchyme. Here, a case of central odontogenic fibroma in a 17-year-old male is reported. Since the present case showed a multilocular radiolucency with partially ill-defined border between the right mandibular condyle and the distal root of the right mandibular third molar, differential diagnosis involved a wide range of pathosis from benign lesions like ameoloblastic fibroma and odontogenic myxoma to more aggressive lesions such as desmoplastic fibroma, juvenile aggressive fibromatosis, or fibrosarcoma.

Central odontogenic fibroma: a case report

Nah, Kyung-Soo Korean Academy of Oral and Maxillofacial Radiology 2011 Imaging Science in Dentistry Vol.41 No.2

Central odontogenic fibroma is a rare odontogenic neoplasm that originates from odontogenic ectomesenchyme. Here, a case of central odontogenic fibroma in a 17-year-old male is reported. Since the present case showed a multilocular radiolucency with partially ill-defined border between the right mandibular condyle and the distal root of the right mandibular third molar, differential diagnosis involved a wide range of pathosis from benign lesions like ameoloblastic fibroma and odontogenic myxoma to more aggressive lesions such as desmoplastic fibroma, juvenile aggressive fibromatosis, or fibrosarcoma.

하악 체부 골절부위에 이환된 백악질 골화성 섬유종: 증례보고

정태영,김소현,조현주,박상준,Jung, Tae-Young,Kim, So-Hyun,Jo, Hyun-Joo,Park, Sang-Jun 대한악안면성형재건외과학회 2010 Maxillofacial Plastic Reconstructive Surgery Vol.32 No.5

Cemento-ossifying fibroma is a true osteogenic neoplasm. It is also called as ossifying fibroma or cementify-ing fibroma. Small lesions seldom cause any symptoms and are detected only on radiographic examination. Large lesions result in a painless swelling of the involved bone. In radiographic features the lesion most often is well defined and unilocular. It may appear completely radiolucent, or more often varying degrees of rdiopacity. It is composed of fibrous tissue that contains a variable mixture of bony trabeculae,cementum-like spherules, or both. Treatment of most lesions generally is enucleation of tumor. However, some lesions which have grown large and destroyed considerable bone, may necessitate surgical resection and bone grafting. This case was the bony lesion that was found by accident in patient with mandibular left body and subcondylar fracture. In radiographic examination, there was a mixed radiolucent and radiopaque lesion in mandibular left body area with fracture line. We treated on mandibular left body and subcondylar fracture and enucleated the lesion on the left body area simultaneously. At surgical exploration, the lesion was well demarcated from the surrounding bone, thus permitting relatively easy separation of the tumor from its bony bed. In histopathologic examination, the lesion contained bony trabeculae and cementum-like spherules within a background of cellular fibrous connective tissue. It finally diagnosed as cemento-ossify-ing fibroma from the result of biopsy.