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      • KCI등재

        칼슘알루미네이트 시멘트 모르타르의 성능 평가

        이승태 한국구조물진단유지관리공학회 2015 한국구조물진단유지관리공학회 논문집 Vol.19 No.6

        본 연구에서는 칼슘알루미네이트 시멘트(CAC) 모르타르의 수화생성물, 강도, 흡수율, 표면전기 저항성 및 염소이온 침투저항성을 실험적으로 고찰하였다. CAC 모르타르의 성능은 보통포틀랜드 시멘트(OPC) 모르타르의 성능과 상호 비교되었다. 실험 결과에 따르면, CAC 모르타르의 주요 수화생성물은 C2AH8 및 CAH10으로 조사되었으며, 압축 및 부착강도는 OPC 모르타르에 비하여 우수하게 나타났다. 뿐만 아 니라, 표면전기 저항성 및 염소이온 침투저항성도 대체적으로 좋은 결과를 나타냄으로서, CAC의 우수한 성능도 확인하였다. 그러나, CAC 모 르타르의 흡수율은 초기재령부터 OPC 모르타르에 비하여 다소 크게 나타남으로써, CAC 경화체의 표면흡수 성능을 개선하기 위한 연구가 더 필요할 것으로 판단된다. 반면, CAC 및 OPC 혼용배합 모르타르의 역학적 성능은 CAC 모르타르에 비하여 대체적으로 다소 떨어지는 것으로 조사됨으로써, CAC계 경화체 제조시 주의가 요구된다. In this study, several properties of mortars made with calcium aluminate cement (CAC) such as hydrated products, strength characteristics, absorption, surface electric resistivity and chloride ions penetration resistance were experimentally investigated. The properties of CAC mortars were compared to those of ordinary portland cement (OPC) mortars. From the test results, it was found that the main hydrated products for CAC mortars were of C2AH8 and CAH10, while CH, ettringite and calcite for OPC mortars. The surface electric resistivity and chloride ions penetration resistance of CAC mortars were significantly beneficial compared to those of OPC mortars. However, it should be noted that the absorption properties of CAC mortars were negatively examined. Thus, it needs to have more study for the improvement of surface absorption of CAC matrices. In addition, the combined mixture of CAC and OPC were ineffective to improve some performances of mortars.

      • Negative regulation of ERα by a novel protein CAC1 through association with histone demethylase LSD1

        Kim, J.,Park, U.H.,Moon, M.,Um, S.J.,Kim, E.J. North-Holland Pub ; Elsevier Science Ltd 2013 FEBS letters Vol.587 No.1

        ERα, a critical transcriptional factor for breast cancer proliferation, is regulated by a complex binding repertoire that includes coactivators and corepressors. Here, we identified a novel class of ERα coregulator called CAC1. The CoRNR box of CAC1 was required for the binding to and inactivation of ERα. CAC1 also associated with histone demethylase LSD1 and suppressed LSD1-enhanced ERα activity. CAC1 impaired recruitment of ERα and LSD1 to the ERα-responsive promoter, leading to greater H3K9me3 accumulation. This effect was reversed by CAC1 depletion. Finally, CAC1 increased paclitaxel-induced cell death in ERα-positive MCF7 cells, which are paclitaxel-resistant. Overall, our study provides the first evidence that CAC1, associated with LSD1, functions as an ERα corepressor, implicating a potential antitumor target in ERα-positive breast cancer. Structured summary of protein interactions: ER-alphaphysically interacts with CAC1 by anti tag coimmunoprecipitation (View Interaction: 1, 2, 3) LSD1physically interacts with CAC1 by anti tag coimmunoprecipitation (View interaction) CAC1binds to ER-alpha by pull down (View interaction) CAC1 and ER-alphacolocalizebyfluorescence microscopy (View interaction)

      • KCI등재

        무증상 성인에서 심혈관질환 위험요소와 관상동맥 석회 수치와의 관계

        문일봉(Il-Bong Moon),손석준(Seok-Joon Sohn) 한국콘텐츠학회 2010 한국콘텐츠학회논문지 Vol.10 No.7

        관상동맥 석회수치(CACS)는 조직학적으로 동맥경화반의 총량과 높은 상관관계를 보이며, 관상동맥의 협착을 예측하는 지표와 향후 허혈성 심장질환 발생의 독립적인 위험인자가 된다. 본 연구는 2006년 1월부터 2008년 12월까지 화순전남대학교병원 건강증진센터에서 건강검진을 목적으로 CACS검사를 시행한 1042명을 대상자로 심혈관질환 위험요소 및 관상동맥 석회수치와 Framingham Risk Scores(FRS)와의 상관관계를 알아보고자 하였다. CACS와 FRS는 남성(OR, 2.38; 95% CI, 1.83-3.11), 여성(OR, 2.12; 95% CI, 1.03-4.35) 모두 관상동맥 석회수치가 없는 군과 비교하여 통계적으로 유의하게 높았으며, CACS와 심혈관질환 위험요인과의 관계에서는 연령과 성별을 통제한 다변량분석에서 여자는 연령(OR, 1.10; 95% CI, 1.06-1.15), 고밀도지단백콜레스테롤(OR, 2.38; 95% CI, 1.04-5.44), 공복혈당(OR, 2.89; 95% CI, 1.16-7.21)이 남자에서는 연령(OR, 1.11; 95% CI, 1.08-1.14), 저밀도지단백콜레스테롤(OR, 2.12; 95% CI, 1.28-3.50), 감마-글루타밀전이효소(OR, 1.73; 95% CI, 1.17-2.55), 당뇨병(OR, 3.92; 95% CI, 1.73-8.89)이 관상동맥 석회수치의 유의한 위험인자로 나타났다. Coronary artery calcium scores(CACS) has been used as surrogate marker for coronary atherosclerosis. We evaluated 1042 patients who visited the Department of Health Promotion Center in Chonnam National University Hospital and had a test of the CACS from January 2006, to December 2008. This study was performed to evaluate the relation of the CACS with Cadiovascular disease(CVD) risk factors and FRS. CACS and FRS was a significant difference between the group whose calcium score was 0 and the group whose calcium scores were 1 in case of men 2.38(95% CI, 1.83-3.11), women 2.12(95% CI, 1.03-4.35). The age-and sex-adjusted odds ratios for predictor of CVD risk factors to women with age was 1.10(95% CI, 1.06-1.15), HDL-cholesterol was 2.38(95% CI, 1.04-5.44), Fasting plasma glucose was 2.89(95% CI, 1.16-7.21), to men with age was 1.11(95% CI, 1.08-1.14), LDL-cholesterol was 2.12(95% CI, 1.28-3.50), gamma -GTP was 1.73(95% CI, 1.17-2.55), Diabetes mellitus medication was 3.92(95% CI, 1.73-8.89). The CACS seems to be a siginificant factor to evaluate the CVD risk factors.

      • KCI등재

        Evaluation of the feasibility of using calcium aluminate composite (CAC) and Acement as additives for regulated set cement

        구자설,유승엽,김진만,최선미,오상윤,한동엽 한양대학교 세라믹연구소 2016 Journal of Ceramic Processing Research Vol.17 No.11

        This work aims to evaluate the feasibility of using calcium aluminate composite (CAC) manufactured from steel slag, quicklycooled with high pressure air, and Acement, produced from CAC and various additives including gypsum as enhancementsfor regulated set cement. To evaluate the performance CAC or Acement as the additives of regulated set cements, CAC andAcement were replaced for the commercially available calcium sulfoaluminate cement (CSA)-based rapid setting cement(RSC). The engineering properties of workability, strength, and elastic modulus of mortar and concrete phases were thentested. From the mortar tests, as the replacement ratio of CAC was increased, the compressive strength of the mortarsignificantly decreased because of reduced amounts of gypsum for ettringite formation. On the other hand, as the replacementratio of Acement including gypsum was increased, the compressive strength increased due to enhanced ettringite formation. From the test results, Acement displayed more favorable results as an additive for the rapid setting cement than CAC. CACcontinued to show good performance at less than 10% of replacement ratio. Concrete testing revealed that mechanicalperformances of compressive, tensile, and flexural strength and elastic modulus all improved by 10% with CAC replacementand by 20% with Acement replacement. However, the resistivity performances for freeze-thaw tests and carbonation slightlydecreased.

      • KCI등재

        RCA-CAC분석을 통해 본 한국의 대EU 수출경쟁력

        김주리 한국외국어대학교 EU연구소 2018 EU연구 Vol.- No.50

        In this study, the export competitiveness of Korea's 20 largest export items in the EU market and the global market is compared and analyzed using the RCA and CAC index in order to analyze the cause of the Korea's Trade Deficit with EU after the Korea-EU FTA. As a result of the RCA-CAC analysis, Korea-EU trade showed a typical trade pattern among developed countries with a capital-intensive export product structure. In terms of technology -intensive items, Korea was in a relatively inferior position compared to the EU, and Korea's export competitiveness in the capital-labor mixed export items was superior to the EU. In particular, the comparative advantages in the EU market since the entry into force of the Korea-EU FTA were automobiles and parts, steel products, oil and cosmetics, and knitting, among which oil and cosmetics were more competitive in export in the EU market than in the international market. Meanwhile, the EU's competitive advantage in the Korean market was automobiles and parts, machinery, ships, and copper products. The European machinery, which has improved its competitiveness in the Korean market since the FTA took effect, has contributed to the increase in Korea's EU imports. Especially, the increase in imports of machinery, which is equivalent to the EU's comparatively inferior export, is the result of the importation of parts and intermediate goods imported from Japan into EU products. Therefore, Korea should identify the cause of its declining competitiveness after the Korea-EU FTA. In the capital-labor mixed export item group, self-help measures should be prepared to strengthen the constitution from price competitiveness to quality competitiveness. In addition, Korea should take a two-sided strategy to enhance import suppression and promote exports through quality differentiation strategies in product groups that are improving competitiveness simultaneously in mutual markets. And the government should actively respond to the EU's safety guard survey on Korean steel products, which are improving their competitiveness in the EU market. 이 연구에서는 한-EU FTA 체결 이후 발생하고 있는 한국의 대EU 무역역조 현상의 원인을 분석하기 위하여 20대 수출품목의 대EU 및 대세계 수출경쟁력을 RCA, CAC지수를 이용하여 비교 분석하고 있다. RCA-CAC분석 결과, 한-EU 무역은 유사한 자본집약형 수출상품구조를 띤 전형적인 선진국 간 무역패턴을 보였고, 기술집약적 품목군에 있어서 한국은 EU에 비해 비교열위 상태이며, 자본-노동 혼합형 수출품목에서는 한국의 수출경쟁력이 EU보다 비교우위를 점하고 있었다. 특히, 한-EU FTA 발효 이후 EU 시장에서 경쟁력이 개선된 비교우위 수출품은 자동차&부품(87), 철강제품(73), 정유/화장품(33), 편물(60)이었고, 그중에서 정유/화장품(33)은 국제시장보다 EU 시장에서의 수출경쟁력이 더 높았다. 한편, 한국시장에서 경쟁력이 개선된 EU의 비교우위품목은 자동차&부품(87), 기계류(84), 선박(89), 구리제품(74)이었고, 기계류(84)도 FTA 발효 이후 한국시장에서 경쟁력이 개선되면서 한국의 대EU 수입 규모를 증가시키는 원인으로 작용하였다. 특히 EU의 비교열위 수출품에 해당하는 기계류(84)의 수입증가는 일본으로부터 수입하던 부품 소재와 중간재 등의 수입이 EU 제품으로 전환된, 한-EU FTA로 말미암는 무역전환 효과의 귀결이라 하겠다. 따라서 한국은 한-EU FTA 체결 이후 대EU 비교열위 상태가 심화되고 있는 수출품목에 대한 원인 규명과 경쟁력 향상방안을 재검토하고, 자본-노동 혼합형 수출품목군에 있어서는 가격경쟁력에서 품질경쟁력으로의 체질 강화를 위한 자구책을 조속히 마련해야 할 것이다. 그리고 상호시장에서 동시적으로 경쟁력이 개선되고 있는 자동차&부품(87) 등의 제품군에 대해서는 품질 차별화 전략을 통해 수입억제력을 제고시키는 동시에 수출촉진을 도모하는 양동 전략을 강구하여야 할 것으로 보인다. 특히, FTA 발효 이후 EU 시장에서 경쟁력이 개선되고 있는 한국산 철강제품에 대한 EU의 세이프가드 조사에 대응하여 정부 차원의 적극적인 대응책이 모색되어야 할 것이다.

      • SCIESCOPUSKCI등재

        Molecular Characterization of Adenylyl Cyclase Complex Proteins Using Versatile Protein-Tagging Plasmid Systems in Cryptococcus neoformans

        ( Yee-seul So ),( Dong-hoon Yang ),( Kwang-woo Jung ),( Won-ki Huh ),( Yong-sun Bahn ) 한국미생물생명공학회 2017 Journal of Microbiology and Biotechnology Vol.27 No.2

        In this study, we aimed to generate a series of versatile tagging plasmids that can be used in diverse molecular biological studies of the fungal pathogen Cryptococcus neoformans. We constructed 12 plasmids that can be used to tag a protein of interest with a GFP, mCherry, 4×FLAG, or 6×HA, along with nourseothricin-, neomycin-, or hygromycin-resistant selection markers. Using this tagging plasmid set, we explored the adenylyl cyclase complex (ACC), consisting of adenylyl cyclase (Cac1) and its associated protein Aca1, in the cAMP-signaling pathway, which is critical for the pathogenicity of C. neoformans. We found that Cac1-mCherry and Aca1-GFP were mainly colocalized as punctate forms in the cell membrane and nonnuclear cellular organelles. We also demonstrated that Cac1 and Aca1 interacted in vivo by coimmunoprecipitation, using Cac1-6×HA and Aca1-4×FLAG tagging strains. Bimolecular fluorescence complementation further confirmed the in vivo interaction of Cac1 and Aca1 in live cells. Finally, protein pull-down experiments using aca1Δ::ACA1-GFP and aca1Δ::ACA1- GFP cac1Δ strains and comparative mass spectrometry analysis identified Cac1 and a number of other novel ACC-interacting proteins. Thus, this versatile tagging plasmid system will facilitate diverse mechanistic studies in C. neoformans and further our understanding of its biology.

      • KCI등재

        소수성 용액이 혼합된 CAC 혼합 모르타르의 배합비에 따른 표면 특성과 소수성에 관한 연구

        윤현웅,박성현,박연준,김영환,오홍섭 한국구조물진단유지관리공학회 2025 한국구조물진단유지관리공학회 논문집 Vol.29 No.1

        본 연구는 시멘트 기반 복합체의 내구성을 높이기 위해 모르타르에 소수성 혼화재를 첨가하는 방식에서 기존의 OPC 시멘트를CAC로 치환하는 시험을 진행했다. 시험 결과, 소수성 혼화재를 첨가하면 모르타르의 소수성은 현저하게 향상되었지만, 재료의 강도는 약해지는 것으로 나타났다. 회귀 분석을 통해 소수성 혼화제의 혼입량과 모르타르의 기계적 특성 간의 상관관계를 정량적으로 도출하였으며, 이를 통해 소수성 혼화제의 혼입량이 증가할수록 모르타르의 강도가 감소하는 경향을 확인했다. 또한, 모르타르 표면의 거칠기와 소수성 사이의 관계를 분석했지만, 명확한 상관관계를 파악하기는 어려웠다. 본 연구는 소수성 혼화제의 최적 혼입량 및 배합비를 설정하는 데 기초 데이터를 제공하며, 모르타르의 성능을 향상시키기 위한 연구 자료로 활용될 수 있을 것으로 판단된다. This study investigated the effects of incorporating hydrophobic admixtures into mortar, replacing Ordinary Portland Cement (OPC) with Calcium Aluminate Cement (CAC), to enhance the durability of cement-based composites. Results showed that while the addition of hydrophobic admixtures significantly improved the hydrophobicity of the mortar, it also led to a decrease in mechanical strength. Regression analysis was conducted to quantitatively determine the correlation between the dosage of hydrophobic admixtures and the mechanical properties of the mortar, revealing a decreasing trend in strength with increasing admixture dosage. Although the relationship between surface roughness and hydrophobicity was explored, a clear correlation was not found. This study provides fundamental data for determining the optimal dosage and mix proportion of hydrophobic admixtures and can be used as a reference for improving the performance of mortar.

      • KCI등재

        Activated carbon (AC)-metal-organic framework (MOF) composite: Synthesis, characterization and dye removal

        Sina Soroush,Niyaz Mohammad Mahmoodi,Bayramali Mohammadnezhad,Abdolreza Karimi 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.9

        Activated carbon (AC), one of the most common adsorbents, and metal-organic framework (MOF), aninteresting class of materials, were used for synthesizing AC/MOF composite by the solvothermal method. The strategydesigned in this paper is to improve the removal and adsorption performance of AC for dye. MIL-53(Fe) was synthesizedon the commercial activated carbon (CAC) to prepare CAC/MIL-53(Fe) composite. Direct Red 23 (DR23)anionic dye was used as a model contaminant. FT-IR, XRD, SEM, and EDX analyses were applied to study the structureand characteristics of CAC/MIL-53(Fe). The parameters (the solution pH, amount of adsorbent dosage, initial dyeconcentration, and contact time) affecting the dye removal efficiency were investigated. The percentage of dye removal(DR23) under optimal conditions by commercial activated carbon and CAC/MIL-53(Fe) was 50% and 99.9%, respectively. The maximal capacity of adsorption was also raised from 50 to 100mg/g. The adsorption isotherm and kineticsfollowed the Langmuir and pseudo-second-order models, respectively

      • KCI등재

        한국과 중국의 대 베트남 수출경쟁력 분석 - 디스플레이산업을 중심으로 -

        김지현 국제e-비즈니스학회 2019 e-비즈니스 연구 Vol.20 No.1

        The purpose of this study is to analyze the export competitiveness of Korean and Chinese display industries in Vietnam and to find countermeasures. For this purpose, CAC, TSI, IE index were used as analysis tools. Analysis results of CAC, Korea has a comparative advantage in Vietnam with HS 8531, HS 8543, HS 853180, China has a low comparative advantage in HS 9013, HS 8529, HS 901380, HS 852990. Analysis results of TSI, Korea has a comparative disadvantage in HS 8473 and a high comparative advantage in HS 901380, HS 853180. China has a comparative disadvantage in HS 8529, HS 852990 and has a comparative advantage in HS 901380, HS 853180. Analysis results of IE, Korea has a high comparative advantage in HS 9013, HS 8543, HS 901380, HS 853180 but, both Korea and China have a very low export consolidation in Vietnam with HS 8531. China is only comparative disadvantage in HS 8531. And all other products have comparative advantage, so competition with Korea is expected to become more intense. As the first response, it is needed education to foster professional human resources by area, government support, industry-academy linkage. Second, support for smooth supply of parts, material price reduction for higher technology development than competitors, domestic production of key parts, and domestic development of major technologies is needed. Finally, in order to prepare for future changes, we should focus on exploring new markets through convergence with various industries. 본 연구의 목적은 베트남시장에서 한국과 중국의 디스플레이산업 수출경쟁력을 분석하고 대응방안 도출에있다. 이를 위해 CAC, TSI, IE지수를 분석도구로 사용하였다. CAC의 분석결과, 한국은 베트남시장에서 HS 8531, HS 8543, HS 853180에 비교우위가 있고, 중국은 HS 9013, HS 8529, HS 901380, HS 852990에 낮지만비교우위가 있다. TSI 분석결과, 한국은 HS 8473에 비교열위, HS 901380, HS 853180에 높은 비교우위를갖는다. 중국은 HS 8529, HS 852990은 비교열위, HS 901380, HS 853180 은 비교우위를 갖는다. IE 결과에서한국은 HS 9013, HS 8543, HS 901380, HS 853180 은 높은 비교우위를 갖지만, HS 8531은 한국과 중국 모두베트남시장에서 수출결합관계가 매우 낮았다. 중국은 HS 8531만 비교열위이고 다른 전 품목은 비교우위를갖고 있어, 한국과 경쟁이 더욱 치열해질 것으로 예상된다. 대응방안으로 첫째, 분야별 전문 인력양성을위한 교육, 정부의 지원, 산·학 연계가 필요하다. 둘째, 경쟁국보다 높은 수준의 기술개발을 위해 원자재가격인하, 부품조달 원활, 핵심부품 국내생산, 주요기술 국내개발 등에 대한 지원이 필요하다. 마지막으로, 미래의변화에 대비하여 다양한 산업과의 융합을 통해 신 시장 개척에 주력해야 할 것이다.

      • CAC를 이용한 긴급도로 보수재의 현장 적용성

        현지수 ( Ji Soo Hyun ),김진만 ( Jin Man Kim ),최홍범 ( Hong Beom Choi ),이하나 ( Ha Na Lee ),구자술 ( Ja Sul Koo ) 한국건축시공학회 2015 한국건축시공학회 학술발표대회 논문집 Vol.15 No.1

        This study was to review the basic characteristics in order to evaluate field application of the emergency road repair materials for development of CAC(Calcium Aluminate Composite) usage. The experiment was conducted with two phases of field and laboratory conditions and the laboratory experiment consisted indoor and outdoor tests for compressive and flexural strength. In the result of an experiment, for the compressive strength test, the specimens that cured in the laboratory conditions were not satisfied the requirement of standards, while the specimens that cured in the field conditions were well satisfied with those. For flexural strength test, the result value was satisfied with the requirement on the standards only in outdoor curing condition of laboratory experiment. Based on these results, it is expected that the CAC can be used as an emergency road repair material for field conditions.

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