일부 大學敎授와 敎職員의 心血關係疾患 危險要因 및 健康行態에 關한 硏究

윤의성,천병철,박미숙,김순덕,염용태 고려대학교 의과대학 1997 고려대 의대 잡지 Vol.34 No.3

We reviewed the health screening record(1996) of a university to compare cardiovascular risk factors and major health behavior of teaching staffs with those of other staffs. The reviewed cardiovascular risk factors were body mass index (BMI), blood pressure (BP), total cholesterol (TCH) and fasting blood sugar (FBS). Smoking, drinking, exercise and diet habits were cheked as major risk factors. We defined the obesty (BMI>25), hypertension (systolic BP 140 or diastolic BP 90 mmHg), hypercholesterolemia (TCH 230mg/dl), and hyperglucosemia (FBS 110mg/dl) , drinking group (alcohol intake 3-4 times a week and over 1 bottle of soju a time), smoking group (smoking over 10 cigarettes a day), non-exercising group(do excercise below 3-4 times a week, and below 30 min a times), unbalanced diet group(do favor salty and spicy food or do favor flesh food). The 1,341(81.7%) of 1,640 staffs were screened in 1996, the teaching staffs were 614(69.3% of 886 teaching staffs) and other staffs (mainly clerks and administrators) were 737(97.7% of 754). 41 (6.7%) of teaching staffs were female and 166(22.4%) of the other staffs were. Among the teaching staffs, there were no below age 30 but 11.5% of them were over 60; in case of the other staffs 11.3% and 2.0% were in each age group. We divided the teaching staffs into medical staffs and non-medical staffs and compare the risk factors of each group. The total number of screened medical staffs were 92(36.2%) of 254, and non-medical staffs were 522 (82.6%) of 632. The results were follows; 1) The frequency of hypertension of each group were significantly different (7.2% in teaching staff, 11.8% in other staffs) after adjusting sex, age, smoking, drinking, exercise, and diet habits by multiple logistic regression (p<0.001). Hyperglucosemia were founded 10.5% and 12.4% in each staffs and the difference were significant after adjusting age, sex and health habits(p=0.005). Teaching staffs had more hypercholesterolemic persons than other staffs(24.3%, 16.3% in each staffs, p=0.019). Obesity frequency was not significantly different. 2) The number of drinking group were 114(18.6%), 208(28.3%) in each staffs, and this difference were significantly different (CMH=38.295, p=0.001). The number of smoker were 140(22.8%) and 274(37.2%) (CMH=58.109, p=0.001). The frequency of non-exercising group and the frequency of unbalanced diet group were not significantly different. 3) The frequency of obesity were 39.1% and 30.9% in each medical and non-medical staffs (CMH=4.414, p=0.036), but this difference remains non-significant after adjusting by the health habits. The frequency of hyperglucosemia of medical staffs (17.4%) were significantly higher than non-medical staffs (9.2%) after adjusting age, sex and the health habits (p=0.0005). Other risk factors were not significantly different. 4) Medical staffs had more smoker(29.4%) than non-medical staffs(21.5%) (CMH=6.401, p=0.011) and more non-exercising persons (27.2%) then non-medical staffs(11.1%) (CMH=12.446, p=0.001). Other health behaviors are not significantly different.

저체중 또는 과체중 청소년에서 캠프 프로그램을 이용한 영양 교육효과에 관한 연구

성미경,승정자,류화춘,박재년,박동연,최미경,조경옥,최선혜,이윤신,김유경,이은주 대한지역사회영양학회 2003 대한지역사회영양학회지 Vol.8 No.4

This study was performed to evaluate the effectiveness of a nutrition education program developed for nutritionally imbalanced adolescents. A summer nutrition camp was held for 23 overweight and 16 underweight subjects. Its effectiveness with regard to was evaluated at the end of the camp and 6 months later. Nutrition knowledge, nutritional attitude, food behavior, nutrient intake, exercise habit and ideal body figures desired by the subjects. The results showed significantly higher nutrition knowledge scores at the end of the camp as compared to those obtained prior to the camp program, and these scores were maintained for at least six months. Nutrition attitude scores also improved after the education program, and these improved scores also lasted for 6 months. However, the food behavior scores measured 6 months after the education program were not significantly different from those obtained prior to the camp. Also, the exercise habit, the ideal body figures and the body figures desired by the subjects remained unchanged. When nutrient intakes of subjects were assessed before the program and 6 months later, the mean daily vitamin C intake was significantly increased after the education program. Also, the intake of iron from plant food sources increased in the overweight subjects, while less iron from animal source were consumed by the underweight subjects. Both groups tended to consume more vegetables and fruits 6 months after the education program which may have contribute to the higher vitamin C and plant-based iron intakes. These results indicate that a 4-day nutrition education camp program sustained changes in nutrition knowledge and nutrition attitude for 6 months. The increased intake of vegetables and fruits was also achieved through this education program. However, changes in dietary behavior in adolescents may require repeated education.

중국 운남성 소수민족무용

최미연,천은혜,김주연 세계민족무용연구소 2002 민족무용 Vol.- No.2

항암화학요법 관련 오심과 구토 완화를 위한 비약물요법에 관한 연구동향

소향숙,최자윤,조인숙,김영재,김지영,김애숙,김옥미,김춘심,김현오,설영애,안정옥,이애리,이영자 성인간호학회 2003 성인간호학회지 Vol.15 No.3

Purpose: Purposes of this study were to understand the current trends on complementary therapy in relieving chemotherapy-induced nausea and vomiting and to suggest the future research direction. Method: Subjects were selected on CINAHL, MEDLINE, Korean Academy Data Base from 1980 to 2001 which used nausea, vomiting, chemotherapy and complementary therapy as key words in experimental studies. Eight korean articles and twenty-one international articles were analyzed in terms of general characteristics, research methods, and types of complementary therapy. Data were analyzed by using descriptive statistical methods. Result: Since 2000, researchers have more actively used complementary therapy. In subject characteristics, mean age was 35.5 years old, 45% of the researchers were performed with high level of incidence of chemotherapy induced vomiting, 14% of them set limit of consecutive cycle during research, and 65% of them did not comment the selecting criteria of sample. About 60% of them were designed post-test only control group: 35% used INV by Rhodes, 31% used Likert scale, and 24% used VAS for dependent variable. Muscle relaxation therapy was mostly applied for relief of nausea and vomiting. Conclusion: Further studies will be needed to control extrinsic variables affecting nausea and vomiting in research design and to accumulate evidence with studies applying various complementary therapies.

신규간호사와 프리셉터가 인지하는 프리셉터의 교수효율성 비교

김지양,김영선,김춘실,박현숙,신미영,윤연숙,조유숙,박미미,유문숙 한국간호과학회 간호행정학회 2009 간호행정학회지 Vol.15 No.2

Objective: The purpose of this study was to compare preceptors and new graduate nurses on their perception of preceptor teaching effectiveness. Methods: The participants were 90 new nurses and 90 preceptors who worked in A medical center. The data were collected from July 1 to September 30, 2008. A cross-sectional descriptive survey was done using a structured questionnaire. Results: New nurses' perception (4.07±.44) of the preceptor teaching effectiveness was significantly higher than perception of the preceptors (3.57±.37). Fifty five percent of new graduate nurses reported a lack of coherence in the preceptor's practice guidelines. For 5 causal factors classified on the teaching effectiveness, the factor of 'Professional knowledge and ability' showed the highest score, but 'Interpersonal and communication skill' got lowest score for both group. Preceptors responded that they did not have enough time to teach well because of their heavy workloads. Conclusions: These results suggest that the preceptors need appropriate compensation and education opportunities, and new graduate nurses need consistent education by the teaching professionals. Therefore, it is important to give preceptors full charge of the preceptorship. Also, it will be necessary to develop education programs to enhance interpersonal and communication skill for preceptors and new nurses.

Inhibitory Effects of an Ethyl Acetate Fraction from Cephalonoplos segetum on Inflammatory Mediators from Lipopolysaccharide-induced RAW 264.7 Macrophages

Chun, Jin-Mi,Cheon, Myeong-Sook,Park, Mi-Kyung,Lee, A-Yeong,Moon, Byeong-Cheol,Ji, Yun-Ui,Kim, Ho-Kyoung The Korean Society for Applied Biological Chemisty 2012 Applied Biological Chemistry (Appl Biol Chem) Vol.55 No.1

Cephalonoplos segetum has been used as an herbal remedy, and is considered to have anti-inflammatory potential. However, its biological mechanism in this treatment process remains unknown. Therefore, the anti-inflammatory activity of the ethyl acetate fraction of C. segetum extracts (CSE-EA), more active than C. segetum extracts (CSE) in murine macrophages, was investigated. Production levels of nitric oxide (NO), prostaglandin $E_2$ ($PGE_2$), tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), and interleukin-$1{\beta}$ (IL-$1{\beta}$) by lipopolysaccharide (LPS)-induced RAW 264.7 macrophages were measured by ELISA. In addition, protein expression levels of inducible NO synthase (iNOS) and cyclooxygenase (COX)-2, and the phosphorylation of mitogen-activated protein kinases (MAPKs) in the LPS-induced macrophages were investigated by Western blotting. The CSE-EA (50, 100 or 200 ${\mu}g/mL$) significantly inhibited NO, $PGE_2$, TNF-${\alpha}$, and IL-$1{\beta}$ production in LPS-induced macrophages in a dose-dependent manner with 50% inhibitory concentration values of 80.4, 104.7, 91.3, and 46.7 ${\mu}g/mL$, respectively. Similarly, CSE-EA reduced protein expression of iNOS and COX-2 and led to the attenuated activation of kinases ERK1/2 and JNK in the macrophages. Results of the present study suggest that the anti-inflammatory effects of CSE-EA are likely due to the down-regulation of NO, $PGE_2$ TNF-${\alpha}$, and IL-$1{\beta}$ and the reduced expression of iNOS and COX-2 via suppression of MAPK signaling pathways in LPS-induced murine macrophages.

수유부의 식이 섭취 및 건강관련 습관이 모유내 비타민 B 함량에 미치는 영향

천윤미(Chun Yun Mi),김영주(Kim Young Ju),장남수(Chang Namsoo) 韓國營養學會 2005 Journal of Nutrition and Health Vol.38 No.4

<i>In Vivo</i> Biocompatibility Study of Electrospun Chitosan Microfiber for Tissue Engineering

Kang, Yun Mi,Lee, Bit Na,Ko, Jae Hoon,Kim, Gyeong Hae,Kang, Kkot Nim,Kim, Da Yeon,Kim, Jae Ho,Park, Young Hwan,Chun, Heung Jae,Kim, Chun Ho,Kim, Moon Suk Molecular Diversity Preservation International (MD 2010 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.11 No.10

<P>In this work, we examined the biocompatibility of electrospun chitosan microfibers as a scaffold. The chitosan microfibers showed a three-dimensional pore structure by SEM. The chitosan microfibers supported attachment and viability of rat muscle-derived stem cells (rMDSCs). Subcutaneous implantation of the chitosan microfibers demonstrated that implantation of rMDSCs containing chitosan microfibers induced lower host tissue responses with decreased macrophage accumulation than did the chitosan microfibers alone, probably due to the immunosuppression of the transplanted rMDSCs. Our results collectively show that chitosan microfibers could serve as a biocompatible <I>in vivo</I> scaffold for rMDSCs in rats.</P>

Interleukin-25 and Interleukin-13 Production by Alveolar Macrophages in Response to Particles

Kang, Chun-Mi,Jang, An-Soo,Ahn, Mi-Hyun,Shin, Jeong-Ah,Kim, Ji-Hye,Choi, Yun-Sung,Rhim, Tai-Youn,Park, Choon-Sik American Thoracic Society 2005 American journal of respiratory cell and molecular Vol.33 No.3

<P>Particle inhalation-induced lung inflammation acts as an adjuvant to allergens or respiratory viral infection in a process that is mediated by macrophages and epitheliums. The production of interleukin (IL)-4 and IL-13 by activated T cells is involved in the augmentation of Th2-type immune responses to particles, and IL-25 induces the synthesis of IL-4 and IL-13. However, whether IL-13 and IL-25 are directly regulated by particle instillation in the lung has not been studied. The aim of this study was to reveal particle induction of IL-13 and IL-25 in the lung. TiO(2) instillation potently induced the mRNA expression for IL-25 and IL-13 in lung tissue extracts 24 h after treatment, as compared with the sham group. Immunostaining for IL-25 and IL-13 showed strong positivity for macrophages in the inflammatory lung lesions of TiO(2)-treated rats. The alveolar macrophages expressed IL-25 and IL-13 24 h after in vitro stimulation with TiO(2) particles in dose- and time-dependent manners, with maximal induction at 24 and 48 h after stimulation, respectively. The sequence of the rat IL-25 gene is 95% homologous with the mouse IL-25 gene. These findings indicate that alveolar macrophages play an important role in particle-induced lung inflammation via direct induction of IL-13 and IL-25 production.</P>

간호학생의 여성건강간호학 임상실습 경험 및 만족도 조사

김윤미 ( Yun Mi Kim ),전나미 ( Na Mi Chun ),이은희 ( Eun Hee Lee ),조인숙 ( In Sook Cho ),안숙희 ( Suk Hee Ahn ),김증임 ( Jeung Im Kim ),허명행 ( Myung Haeng Hur ),이숙희 ( Sook Hee Lee ),이혜경 ( Hae Kyung Lee ),정재원 ( Chae Weo 여성건강간호학회 2011 여성건강간호학회지 Vol.17 No.3

Purpose: The purpose of this study was to identify students` experiences of performance and their satisfaction with clinical nursing practice in Women`s health nursing. Methods: Data was collected using questionnaire consisting of 104; 89,; and 82 nursing activities with 12; 10; and 7 domains for delivery floor, obstetric, and gynecologic wards retrospectively. Five hundred ninety nursing students from 10 four year and one three year colleges, were recruited and selected for data collection. Results: Site specific core nursing activities among top 15 items of performed experience were: interpreting fetal monitoring; massage for pain reduction; breathing technique; perineal pad change; non stress test; manual check for uterine contraction; and position change for the delivery floor. Experiences of clinical nursing practice for the obstetric ward and the gynecologic ward were identified and ranked as well. Observation of delivery, measurement & test during labor and observation of anesthesia and operation were the highest ranked activity domains of satisfaction for delivery floor, obstetric and gynecologic wards retrospectively. Conclusion: Discussions are needed to standardize curriculum for clinical practice in women`s health nursing initiated at the level of Korean Society of Womens` Health Nursing by reflecting this result. Strategic approaches are emphasized in order to enhance a collaboration between clinical fields and colleges.