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CFD-DEM simulation on the complex gas-solid flow in a closed chamber with particle groups
An Chen,Yonggang Yu 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.11
There is a complex gas-solid flow in the cylindrical closed chamber during the interior ballistic process in a modular-charge gun launch. The motion and the distribution of particles in the flow have significant effects on the combustion stability in the interior ballistic process. Therefore, the solid particle-scale details of the gas-solid flow in the closed chamber with hollow-cylindrical particle groups were numerically simulated by using the computational fluid dynamics combined with the discrete element method (CFD-DEM). The results show that the particle final distribution is composed of a gentle-slope accumulation, a horizontal accumulation, and a steep-slope accumulation. Thereinto, the voidage of the steep-slope accumulation is decreased with the axial position far away from modules. With the increase of the initial spacing between two particle groups, the axial length of the steep-slope accumulation is increased exponentially, whereas the tangent value of the inclined angle is decreased exponentially.
천핑위안 민족문학사학회 2000 민족문학사연구 Vol.16 No.-
The essay, dealing with heroic novels of Jin-Yong(金庸), is extracted from professor Chen's latest work, the Form and the Structure of the History of Literature(1999.3, Guangsi Education Publishing). The author of the essay, Chen Ping-Yuan received M. A in literature at Zhongshan University and Ph. D at Beijing University and presently he is the professor of the Chinese literature department and the academic adviser of the doctor's course in Beijing University. His academic concern has wide range, such as 20th century's Chinese literature, modem Chinese history of science, Chines novel and Chinese prose, and it came out in his writings, like Narrative Form of Chinese Novel and Chines Novel of 20th Century. Hitherto, Chinese heroic novel was always under-valued in the field of literature but the enormous popularity of one writer, Jin-Yong, was so powerful that his heroic novel became the matter of scientific concern not mention in Chinese academic world but in the international academic world. The essay, with reflection, criticizes his success from the viewpoint of modern Chinese literature so its subject is the interior case of the Chinese literature. For all, some issues, like the problem of vulgarity in literature, the excessive inclination toward pure literature and the inheritance of the literary tradition, which arise from argument on Chinese heroic novel, are crucial points of the history of Korean new literature. Therefore, our reviewing this essay can be a lesson for studying the history of modern Korean literature.
Chen Peng-Ciao,Chen Yu-Ju,Yang Chia-Chen,Lin Ting-Ti,Huang Chien-Chu,Chung Chi-Hsiang,Sun Chien-An,Chien Wu-Chien 대한남성과학회 2022 The World Journal of Men's Health Vol.40 No.3
Purpose: Some evidence suggests that male infertility increases the risk of cardiovascular diseases (CVDs). However, the evidence in Asian populations is relatively scarce. The aim of this study is to determine whether male infertility increases the risk of CVDs. Materials and Methods: We used inpatient and outpatient data for the years 2000 to 2015 from the Taiwanese Longitudinal Health Insurance Database. We enrolled 7,016 males over 18 years old and diagnosed with male infertility. Of these, 2,326 matched our inclusion criteria and were assigned to the study group. For each infertility patient, four comparison patients were frequency-matched by age and index date to form a control cohort comprising 9,304 patients. Cox proportional hazards analysis was used to estimate the association between male infertility and CVDs. Results: After a 15-year follow-up, the incidence rate of CVDs was higher in the infertility group than the control group (1,460.23 and 1,073.70 per 100,000 person-years, respectively). The Cox proportional hazards regression analysis revealed that the adjusted HR for CVDs was 1.472 for the infertility group (95% CI, 1.288–1.683; p<0.001) relative to the control group. The Kaplan–Meier analysis of the cumulative incidence of CVDs in the two groups showed that the cumulative risk curve for CVDs was significantly higher for the infertility group than the control group. Conclusions: This study shows that men with infertility have a higher risk of developing incident CVDs. In the future, healthcare providers should pay attention to these patients because of their higher health risks.
Study on Evaluation Model of Urban resilience in response to Flood
Chen, An,SHI Yu,CHEN Yinghua 한국도시행정학회 2019 한국도시행정학회 학술발표대회 논문집 Vol.2019 No.12
Flood disaster is a kind of natural disaster that tests the level of the urban resilience, for it’s strong sudden occurrence, high frequency and serious loss to urban population and wealth. This paper analyzes the influencing factors of urban resilience, constructs the evaluation model of urban resilience to deal with flood disasters, and takes urban resistibility, adaptability and recovery as the three first-level indexes, ecological resistance and economy resistance, infrastructure resistance, disaster intensity, direct loss, infrastructure recovery and psychological recovery time as the second grade index. 22 tertiary indicators such as annual average precipitation and forest coverage were selected for assessment. The evolution law of evaluation model is also discussed from the stage of flood development. Finally, the data of Super typhoon “Mangkhut” in Guangdong Province landing in 2018 are selected for case analysis, and the urban resilience level to flood in Guangdong Province was obtained, which provided a reference for rationally responding to flood risks and carrying out the construction of urban resistance to flood.
An Jen Chiang,Min-Yu Chen,Chia-Sui Weng,Hao Lin,Chien-Hsing Lu,Peng-Hui Wang,Yu-Fang Huang,Ying-Cheng Chiang,Mu-Hsien Yu,Chih-Long Chang 대한부인종양학회 2017 Journal of Gynecologic Oncology Vol.28 No.5
Objective: The malignant transformation (MT) of ovarian mature cystic teratoma (MCT)to squamous cell carcinoma (SCC) is very rare. This study analyzed cases from multiplemedical centers in Taiwan to investigate the clinicopathologic characteristics, treatment, andprognostic factors of this disease and reviewed related literature. Methods: Pathological reports of 16,001 patients with primary ovarian cancer who weretreated at Taiwan medical centers from 1990 to 2011 were reviewed. In total, 52 patients withMT of MCT to SCC were identified. Results: Among all ovarian MCTs, the incidence of MT to SCC is 0.2%. The median age ofpatients was 52 years (range, 29–89 years), and the mean tumor size was 10.5 cm (range, 1–40cm). We analyzed the patients in our study and those in the literature and determined thatearly identification and complete surgical resection of the tumor are essential for long-termsurvival. In addition, adjuvant chemotherapy or concurrent chemoradiotherapy can be usedto treat this malignancy. Old age, large tumor size (≥15.0 cm), and solid components in MCTsare suitable indicators predicting the risk of MT of MCT to SCC. Conclusion: Similar to general epithelial ovarian cancers, the early detection of MT of MCTto SCC is critical to long-term survival. Therefore, older patients with a large tumor or those with a tumor containing a solid component in a clinically diagnosed MCT should beevaluated to exclude potential MT to SCC.
Acute Hepatitis Due to Agomelatine Use in Elderly Women with Depression: Case Series
Cheng-Chen Chang,Yen-Jen Chen,Yu-An Chen,Yi-Cheng Liao 대한정신약물학회 2021 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.19 No.4
Although agomelatine may be associated with an increased risk of hepatotoxicity, the incidence rate of acute hepatitis seemed divergent between clinical trials and daily practice. Whether aging or gender is a risk factor in developing hepatotoxicity due to agomelatine is not clear. We present 3 older female cases with acute hepatitis occurring due to highly probable idiosyncratic drug-induced liver injury caused by agomelatine. From these cases, regular surveillance on liver function in the older women taking antidepressants would be of benefits.
Moscatilin Induces Apoptosis and Mitotic Catastrophe in Human Esophageal Cancer Cells
Chien-An Chen,Chien-Chih Chen,Chien-Chang Shen,Hen-Hong Chang,Yu-Jen Chen 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.10
Moscatilin, a bibenzyl derivative from the orchid Dendrobium loddigesii, has been shown to possess anticancer activity. We examined the effect of moscatilin on human esophageal cancer cells, including squamous cell carcinoma (SCC) and adenocarcinoma (ADC) cells and its possible mechanisms. Moscatilin suppressed the growth of both the histological cell lines in a dose- and time-dependent manner. Morphological changes indicative of apoptosis and mitotic catastrophe were observed following moscatilin treatment. The population of cells in the sub-G1 phase and polyploidy phase significantly increased after treatment. Immunofluorescence revealed multipolar mitosis and subsequent multinucleation in moscatilin-treated cells, indicating the development of mitotic catastrophe. Western blot showed a marked increase in expressions of polo-like kinase 1 and cyclin B1 after exposure to moscatilin. In conclusion, moscatilin inhibits growth and induces apoptosis and mitotic catastrophe in human esophageal SCC- and ADC-derived cell lines, indicating that moscatilin has broad potential against esophageal cancer
Advanced Application of Centralized Control for a Scanning Mirror System Based on EtherCAT Fieldbus
Ruei-Yu Huang,Yen-Jen Chen,Yu-Xian Chen,Chung-Wei Cheng,Mi-Ching Tsai,An-Chen Lee 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.3
Distributed control is the most popular control strategy for controlling numerous slave devices. However, the performance of slave devices is hard to improve because the control algorithm is handled by the commercial slave devices. Therefore, this paper proposes a hybrid control structure that follows the concept of centralized control strategy and handles part of the control loop on the master computer in a distributed control system through EtherCAT fieldbus. In this study, different advanced control methods such as robust control and learning control were applied to handle the position control loop of a scanning mirror system in a selective laser melting (SLM) system with stringent demand of position error around 40 µm based on EtherCAT fieldbus. By designing a proper controller, the experiment results showed that the tracking performance was significantly improved. The tracking error dropped by about 80% after the proposed hybrid control structure was applied. By applying the proposed hybrid control structure, one can improve the high-performance-requirement devices, while reducing the calculationburden of the master computer for other low-performance-requirement devices by retaining the benefit of distributed Control.