3-아미노-1H-피라졸-4-카르복실산 에틸의 디아조화와 결합반응;피라졸로아진의 합성

Youssef, Ayman M.S.,Faty, Rasha A.M.,Youssef, Mohamed M. 대한화학회 2001 대한화학회지 Vol.45 No.5

피라졸로아진은 농업이나 의약품에서 매우 유용한 화합물등이다. 본 논문에서는 몇 가지 새로운 피라졸로아진의 합성을 보고하고자 한다. 표제 화합물인 3-아미노-1H-피라졸-4-카복실산 에틸을 다이아조화한 후 활성화된 메틸렌 화합물들과 반응시키고 고리화하여 피라졸로[5,1-c][1,2,4]트라이아진 유도체들을 합성하였다. 또한 표제 화합물을 $\alpha$-치환된 신남나이트릴과 반응시켜 피라졸로[1,5-a]피리미딘 유도체들을 합성하였다. 새로 합성된 화합물들의 구조는 화학적 방법과 분광학적 방법을 사용하여 확립하였다. Pyrazoloazines are extremely useful in agriculture and medicine. The main objective of this article is to synthesize some new pyrazoloazines. Ethyl 3-amino-1H-pyrazole-4-carboxylate undergoes diazotization, couples with activated methylene compounds and cyclizes to form pyrazolo[5,1-c][1,2,4]tri-azine derivatives. The title compound also reacts with $\alpha$-substituted cinnamonitriles to produce pyrazolo[1,5-a]pyrimidine derivatives. Structures of newly synthesized compounds are established via chemical and spectral methods.

Morphological classification, anatomical variations, innervation patterns, musculocutaneous nerve relation of the coracobrachialis muscle: anatomical study and clinical significance

Ashraf Youssef Nasr,Rawan Ashraf Youssef 대한해부학회 2024 Anatomy & Cell Biology Vol.57 No.2

The anatomical variations of coracobrachialis muscle (CBM) are of great clinical importance. This study aimed to elucidate the morphological variations, innervation patterns and musculocutaneous nerve (MCN) relation to CBM. Upper limbs of fifty cadavers (30 males and 20 females) were examined for proximal and distal attachments, innervation pattern of CBM and its relation to MCN. Four morphological types of CBM were identified according to number of its heads. The commonest type was the two-headed (63.0%) followed by the single belly (22.0%), three-headed (12.0%) and lastly four headed (3.0%) type. Moreover, an abnormal insertion of CBM was observed in four left limbs (4.0%); one inserting into the medial humeral epicondyle, the second into the upper third of humeral shaft, the third one in the common tendon of biceps, and the fourth one showing a bifurcated insertion. Also, four different innervation patterns of CBM were identified including MCN (80.0%), lateral cord (14.0%), lateral root of median nerve (4.0%), and median nerve itself (2.0%). The course of MCN was superficial to the single belly CBM (19.0%) and in-between the heads in the other types (71.0%). Measurements of the length and original distance of CBM muscular branches originating from MCN revealed no sex or side significant difference. Awareness of the anatomic variations, innervation patterns, and MCN relation of CBM is imperative in recent diagnostic and surgical procedures to obtain definite diagnosis, effective management and good outcome.

Isolated Sudden Bilateral Neurosensory Hearing Loss as a Presentation of Lyme Neuroborreliosis: A Case Study

Rochd Sara,Benhoummad Othmane,Salhi Salma,Lakhdar Youssef,Rochdi Youssef,Raji Abdelaziz,Oualhadj Hamza,Kamouni Youssef El,Zouhair Said 대한청각학회 2024 Journal of Audiology & Otology Vol.28 No.1

Lyme neuroborreliosis (LNB) is a rare but potentially serious manifestation of Lyme disease, caused by the spirochete <i>Borrelia burgdorferi</i>. Although LNB can affect various neurological systems, neurosensory hearing loss as the sole presentation is uncommon. We report a case of a 23-year-old woman who presented with a 2-month history of temporal headache, tinnitus, and instability, which was followed by sudden bilateral hearing loss without any other associated symptoms. Pure-tone audiometry revealed profound bilateral hearing loss. Serological testing for various pathogens was negative, except for <i>B. burgdorferi</i> IgM, which was confirmed using Western blot analysis. The patient received doxycycline treatment; unfortunately, no recovery of hearing was observed. This case report highlights the importance of considering LNB as a potential cause of neurosensory hearing loss, particularly in areas where Lyme disease is endemic, as well as the need for timely diagnosis and treatment to prevent potential complications.

Towards Robust Key Extraction from Multipath Wireless Channels

Youssef El Hajj Shehadeh,Omar Alfandi,Dieter Hogrefe 한국통신학회 2012 Journal of communications and networks Vol.14 No.4

This paper tackles the problem of generating shared secret keys based on the physical characteristics of the wireless channel. We propose intelligent quantization mechanisms for key generation,achieving high secret bits generation rate. Moreover, some practical issues affecting the performance of the key generation mechanism are deeply investigated. Mainly, we investigate the effects of delay and mobility on the performance and we enhance the key generation mechanism accordingly. As a result, this paper presents a framework towards robust key generation from multipath wireless channels.

Traumatic cerebrospinal fluid leakage following septorhinoplasty

Youssef, Ahmed,Ahmed, Shahzad,Ibrahim, Ahmed Aly,Daniel, Mulvihill,Abdelfattah, Hisham M.,Morsi, Haitham Korean Society of Plastic and Reconstructive Surge 2018 Archives of Plastic Surgery Vol.45 No.4

Septoplasty/septorhinoplasty is a common ear, nose and throat procedure offered for those patients with deviated septum who are suffering from nasal obstruction and functional or cosmetic problems. Although it is a basic and simple procedure, it could lead to catastrophic complications including major skull base injuries which result in cerebrospinal fluid (CSF) leaks. We describe two different cases of traumatic CSF leaks following septoplasty/septorhinoplasty at two different sites. The first patient suffered a CSF leak following septoplasty and presented to Alexandria University Hospital. The leak was still active at presentation and identified as coming from a defect in the roof of the sphenoid sinus and was repaired surgically. The second patient presented 4 days after her cosmetic septorhinoplasty with a CSF leak and significant pneumocephalus. She was managed conservatively. Understanding the anatomical variations of the paranasal sinuses and implementing proper surgical techniques are crucial in preventing intracranial complications when performing either septoplasty or septorhinoplasty. A good quality computed tomography of the nose and paranasal sinuses is a valuable investigation to avoid major complications especially CSF leaks following either procedure.

Seismic performance of concrete frames reinforced with superelastic shape memory alloys

Youssef, M.A.,Elfeki, M.A. Techno-Press 2012 Smart Structures and Systems, An International Jou Vol.9 No.4

Reinforced concrete (RC) framed buildings dissipate the seismic energy through yielding of the reinforcing bars. This yielding jeopardizes the serviceability of these buildings as it results in residual lateral deformations. Superelastic Shape Memory Alloys (SMAs) can recover inelastic strains by stress removal. Since SMA is a costly material, this paper defines the required locations of SMA bars in a typical RC frame to optimize its seismic performance in terms of damage scheme and seismic residual deformations. The intensities of five earthquakes causing failure to a typical RC six-storey building are defined and used to evaluate seven SMA design alternatives.

Hazard identification and scenario selection of ship grounding accidents

Youssef, Samy Adly Mansour,Paik, Jeom Kee Elsevier 2018 Ocean engineering Vol.153 No.-

<P><B>Abstract</B></P> <P>The objectives of the present paper are to identify the hazard of ship grounding; where a ship runs on a rock with a forward speed, and to select a set of credible scenarios with a limited number that can still represent all possible situations of the accidents. For this purpose, the statistics of ship grounding accidents recorded by authorities for the period of 46 years during 1970–2016 are collated. An extensive analysis is undertaken to examine the statistical characteristics in association with random variables influencing the consequence of grounding. A total of six parameters, namely ship's forward speed, ship's trim angle, rock tip eccentricity, rock length, rock width and rock height are considered as random variables where the displacement or mass of the grounded ship is fixed. Each of the random variables is then formulated with a probability density function. A sampling technique is applied to the probabilistic selection of the grounding scenarios which are to be used for the consequence analysis within the framework of quantitative risk assessment. Important insights developed from the present study are discussed. Details of the analyses are documented.</P> <P><B>Highlights</B></P> <P> <UL> <LI> This article aims to identify the hazard of ship grounding to select a set of scenarios represent all possible situations. </LI> <LI> Statistics of ship grounding accidents recorded by authorities are collated. </LI> <LI> Extensive analyses are performed to examine the statistical characteristics with random variables of grounding. </LI> <LI> A sampling technique is applied to the probabilistic selection of the grounding scenarios. </LI> <LI> Selected credible scenarios are essential within the framework of quantitative grounding risk assessment and management. </LI> </UL> </P>

Water Vapor Adsorption and Hydrogen Peroxide Decomposition on Date Pit Carbonization Products

Youssef, A.M.,El-Nabarawy, Th.,Ahmed, S.A. Sayed,Rashwan, W.E. Korean Carbon Society 2005 Carbon Letters Vol.6 No.4

Carbonization products C1, C2, C3, C4 and C5 were prepared by the carbonization of date pit in limited air, at 500, 600, 700, 800 and $1000^{\circ}C$, respectively. C1-V-600, C3-V-600, C1-V-1000 and C3-V-1000 were prepared by thermal treatment of C1 and C3 under vacuum at 600 and $1000^{\circ}C$. The textural properties were determined from nitrogen adsorption at 77 K and from carbon dioxide adsorption at 298 K. The surface pH, the FTIR spectra and the acid and base neutralization capacities of some carbons were investigated. The amounts of surface oxygen were determined by out-gassing the carbon-oxygen groups on the surface as $CO_2$ and CO. The adsorption of water vapor at 308 K on C1, C2, C3 and C4 was measured and the decomposition of $H_2O_2$ at 308 K was also investigated on C1, C2, C3, C4 and C5. The surface area and the total pore volume decreased with the rise of the carbonization temperature from 500 to $1000^{\circ}C$. The adsorption of water vapor is independent on the textural properties, while it is related to the amount of acidic carbon-oxygen groups on the surface. The catalytic activity of $H_2O_2$ decomposition does not depend on the textural properties, but directly related to the amount of basic carbon-oxygen complexes out-gassed as CO, at high temperatures.

On the Nonlinear Impact of Oil Price Shocks on the World Food Prices Under Different Markets Conditions

Youssef Manel,Mokni Khaled 한국국제경제학회 2021 International Economic Journal Vol.35 No.1

This paper investigates the impact of oil price shocks on the world food prices. We use the structural VAR model to disentangle oil price shocks into supply, aggregate demand, and oil-specific demanddriven shocks. Moreover, we employ a new approach based on the Markov regime-switching quantile regression (MRS-QR) model to investigate the response of food prices to different oil price shocks. Based on monthly data from 1992 to 2018, results show that the reaction of food prices to different structural oil shocks depends on the oil price regimes and varies in significance, sign, and size throughout the food market conditions. Besides, the increases in regression coefficients and smoothed probability during food and oil crisis periods confirm the existence of contagion effects between oil and food markets. Moreover, we find that the supply and aggregate demand shocks do not show a strong contribution to the presence of this phenomenon. Conversely, oil-specific demand shocks represent the main factor that contributes to contagion between oil and food markets.

Stability in functional difference equations with applications to infinite delay Volterra difference equations

Youssef N. Raffoul 대한수학회 2018 대한수학회보 Vol.55 No.6

We consider a functional difference equation and use fixed point theory to obtain necessary and sufficient conditions for the asymptotic stability of its zero solution. At the end of the paper we apply our results to nonlinear Volterra infinite delay difference equations.