다소성 골괴사

서유성,박형근,최형석,김연일,이병일 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.2

In case of the occurrence of osteonecrosis at three or more anatomical location, it is defined as multifocal osteonecrosis, but still any king of study with references hasn't been reported in Korea. The patient who had admitted due to the pain in both knee joints, both hip joints and left ankle joint and we diagnosed as multifocal osteonecrosis by using bone scan and magnetic resonance imaging. To relieve right knee joint and left hip joint pain, we perfomed arthroplasty. Here we present one case report of multifocal osteonecrosis through analysis by patient's history and hematologic examination and provide a review of the literature.

복수과 진료 환자의 중복 처방에 대한 분석 및 평가

이지은,장혜경,오지영,유윤경,김현지,임숙인,연숙희,강진숙,최귀령 한국병원약사회 2003 병원약사회지 Vol.20 No.1

In an aging society, there is an increasing possibility of the duplication of the drugs given to patients because they take many kinds of drugs. Among the prescriptions given to the patients who was treated at multiple ambulatory clinics in St. Mary's hospital for one month of September, 2002, in which drugs that has identical or similar effects are prescribed, we analysed and evaluated them by patients' characteristics, kinds of medication, severity of side effects on a case by case basis. More, we assessed the potential additional costs. As a result of this study, the duplication rate turned out to be 6.69% and it was shown that the proportion of the elderly patients over 60 was high. The gastro-intestinal medications took up a large part and most of the cases showed that the danger caused by double taking of medicine was slight, but there were some examples in which the serious side effects were predicted. Expected additional costs were the average 11.349 won and it ranges from the minimum of 56 won to the maximum of 135,720 won. In conclusion, the management of drug histories of the patients who need the plural treatments is very important and the necessity of the individual and professional guidance of taking medicines for the elderly patients is emerged, too.

천마가 중대뇌동맥 폐쇄 흰쥐의 신경세포 자연사에 미치는 영향

윤유석 ( You Suk Youn ),이종수 ( Jong Soo Lee ) 한방재활의학과학회 2009 한방재활의학과학회지 Vol.19 No.3

Objectives: This study evaluates neuroprotective effect of Gastrodiae Rhizoma on apoptosis in the cerebral infarct. Methods: Cerebral infarct was induced by the middle cerebral artery occlusion (MCAO) for 2 hours with intraluminal thread method in Sprague-Dawley rats. Then ethanol extract of Gastrodiae Rhizoma was administered orally for 3 days. Infarct area and volume were evaluated with TTC staining. Neuronal apoptosis was identified with TUNEL labeling. Apoptosis modulatory effect was observed with immunohistochemical Bax, Bcl-2, iNOS, and MMP-9 expressions in penumbra. Results: 1. Ethanol extract of Gastrodiae Rhizoma reduced infarct size partly and volume significantly of in the MCAO rat brain. 2. Ethanol extract of Gastrodiae Rhizoma reduced TUNEL positive cell ratio in the penumbra of MCAO rat brain significantly. 3. Ethanol extract of Gastrodiae Rhizoma suppressed Bax, iNOS and MMP-9 expression in the penumbra of MCAO rat brain significantly. 4. Ethanol extract of Gastrodiae Rhizoma did not change Bcl-2 expression in the penumbra of MCAO rat brain. But expression ratio of Bcl-2 against Bax was increased in the Gastrodiae Rhizoma group. Conclusions: These results suggest that Gastrodiae Rhizoma plays an anti-apoptotic neuroprotective effect through suppression of Bax, iNOS, and MMP-9 expressions and relative up-regulation of Bcl-2 in the ischemic brain tissue.

요추 추간판탈출증 환자에 대한 한약, 봉독약침, 침, 추나요법의 유효성 평가

윤유석 ( You Suk Youn ),박원상 ( Won Sang Park ),하인혁 ( In Hyuk Ha ),이종수 ( Jong Soo Lee ),신현대 ( Hyun Dae Shin ) 한방재활의학과학회 2008 한방재활의학과학회지 Vol.18 No.1

Objectives : To investigate therapeutic outcomes of back pain modalities in patients with disc herniation; Korean medical treatments(Herbal medicine, chuna therapy, acupuncture, bee-venom acupuncture.). Methods : Operation(OP) recommended 20 patients with lumbar disc herniation were treated with chuna therapy, acupuncture, bee-venom acupuncture one times a week and took herbal medicine after a meal two times daily. The patients` symptoms were assessed 1 week, 2 week, 4 week, 6 week, 8 week by Visual analogue scale(VAS), Oswestry disability index(ODI), 36-Item short-form health survey(SF-36). Results : 1. VAS(LBP and Sciatica) score was significantly improved after 8 weeks (P<0.05). 2. ODI, SF-36 score was significantly improved after 8 weeks (P<0.05). 3. There were significant changes in physical functioning(PF), bodily pain(BP), social functioning(SF), role emotinal(RE), mental health(MH) score of SF-36 after 8 weeks (P<0.05). Conclusions : This study suggests that Korean medical treatment(Herbal medicine, chuna therapy, acupuncture, bee-venom acupuncture) can be applicable to improve symptoms in patients with lumbar disc herniation.

요추 추간판탈출증 환자의 발병시기에 따른 보존적 치료 결과 비교 연구

윤유석 ( You Suk Youn ),이종수 ( Jong Soo Lee ),하인혁 ( In Hyuk Ha ),김주원 ( Joo Won Kim ),권혁준 ( Hyeok Joon Kwon ) 한방재활의학과학회 2008 한방재활의학과학회지 Vol.18 No.4

Objectives : To investigate therapeutic outcomes of back pain modalities in patients with disc herniation according to the duration by treated with herbal medicine, chuna, acupuncture, bee-venom acupuncture. Methods : We separated 36 patients with disc herniation into three group according to duration; acute patients within 4 week, subacute patients within 5-12 week, and chronic group within 13-24 week. 36 patients with lumbar disc herniation were treated with chuna therapy, acupuncture, bee-venom acupuncture one times a week and took herbal medicine after a meal two times daily. The patients` symptoms were assessed 1 week, 2 week, 4 week, 8 week by Visual analogue scale(VAS), Oswestry disability index(ODI), 36-Item short-form health survey(SF-36). Results : 1. ODI of disability of daily activities showed significantly decreased in acute stage group compared to subacute and chronic stage groups(P<0.05). 2. Physical functioning(PF), bodily pain(BP), social functioning(SF) score of SF-36 showed significantly increased in acute stage group compared to subacute and chronic stage groups(P<0.05). Conclusions : This study suggests that acute stage group compared to subacute and chronic stage groups in patients with lumbar disc herniation is the more effective to improve symptoms treated with herbal medicine, chuna therapy, acupuncture, bee-venom acupuncture.

추나요법 후 악화된 요추 추간판 탈출증 1례

윤유석(You-Suk Youn),조재흥(Jae-Heung Cho),류한진(Han-Jin Ryu),이종수(Jong-Soo Lee) 척추신경추나의학회 2004 대한추나의학회지 Vol.5 No.1

The occurrence of neurologic symptom, for example cauda equina syndrome or disc rupture after Chuna treatment seems to be an uncommon event considering the large number of Chuna treatment performed. We experienced a woman who developed sudden complication after lumbar Chuna treatment. Patients in spinal hernation undergone Chuna treatment can be the causative factor in neurological symptom and must be considered in each case. Therefore, physicans and patients should be aware that neurological complication may occur as a result of lumba Chuna treatment.

중풍 하지마비의 재활에 건측 상지 운동요법이 미치는 효과

윤유석 ( You Suk Youn ),정석희 ( Seok Hee Chung ),이종수 ( Jong Soo Lee ) 한방재활의학과학회 2004 한방재활의학과학회지 Vol.14 No.2

Objective: The muscle pattern excercise(MPE) is freqeuntly usde to enhance stroke rehabilitation. and the electroacupunture(EA) is also used to facililitate stroke rehabilitation. Although many studies have indicated that each MPE and EA might improve the motor and functional recovery, there is no study about using MPE and EA simultaneously for effective treating for stroke rehabilitation especially lower extremity function. So we compare the effect between electroacupuncture on affected lower extremity and simultaneously elbow exercise on unaffected upper extremity and only electroacupuncture on affected lower extremity. Methods: 53 stroke patients with hemiplegic stroke were randomized into two groups. 28 patients were treated by electroacupuncture on affected lower extremity and simultaneously elbow exercise on unaffected upper extremity. The other 25 patients were treated by only electroacupuncture on affected lower extremity. The study was applicated a day for 20 days. The frequency of stimulation was 2Hz and intensity was set at a level sufficient to include muscle contraction. The elbow exercise was elbow flexion and extension. Outcome were assessed by weight difference of both leg, Fugl-Meyer score, Medical research council scale, modified Ashworth sclae, modified Barthel index and NIH. Results: By the end of treatment, the sample group showed significantly more improvement than the control group in the section of weight difference of both leg, Fugl-Meyer score, Motor Power, modified Barthel index. Conclusion: These results support that electroacupuncture on affected lower extremity and simultaneously unaffected elbow exercise is more effective than only electroacupuncture on affected lower extremity for Stroke rehabilitation.

중풍환자의 보행회복에 대한 대칭패턴운동을 겸한 전침의 효과

윤유석 ( You Suk Youn ),심우진 ( Woo Jin Shim ),이종수 ( Jong Soo Lee ),김성수 ( Sung Soo Kim ) 한방재활의학과학회 2004 한방재활의학과학회지 Vol.14 No.1

Objectives: Not only but also the muscle pattern excercise(MPE) is freqeuntly used to enhance gait rehabilitation after stroke. Although many studies have indicated that each EA and MPE might improve the gait and functional recovery, there is no study about using EA and MPE stimulateously for effectively treating for gait rehabilitation and funtional recovery after stroke. So we compare the effectiveness between electroacupuncture on affected lower extremity and stimulateously muscle pattern exercise on unaffected upper extremity and only electroacupuncture on affected lower extremity. Methods: 33 stroke patients with hemiplegic stroke were randomized into two groups. 18 patients were treated by electroacupuncture on affected lower extremity and stimulateously muscle pattern exercise on unaffected upper extremity. The other 15 patients were treated by only electroacupuncture on affected lower extremity. The study was applicated a day for 20 days. The frequency of stimulation was 2Hz and intensity was set at a level sufficient to include muscle contraction. The muscle pattern exercise was elbow extension. Outcome were assessed by weight difference of both leg, modified Barthel index and temporal distant gait analysis, for example gait velocity, cadence, stride length, steps length, based of support. Results: By the end of treatment, the sample group showed significantly more improvement than the control group in the section of weight difference of both leg, cadence, stride length, steps length. Conclusions: These results support that electroacupuncture on affected lower extremity and stimulateously muscle pattern exercise is more effective than only electroacupuncture on affected lower extremity for gait rehabilitation.

Spontaneous uterine rupture at 22 weeks’ gestation in women who underwent abdominal adenomyomectomy

( You Ri Lee ),( Jee Youn Hong ),( Ji-hee Sung ),( Suk-joo Choi ),( Soo-young Oh ),( Cheong-rae Roh ) 대한산부인과학회 2021 대한산부인과학회 학술대회 Vol.107 No.-

Effects of Pretreatment Waters on Microbial Control and Sanitation of Horticultural Products

You-Jin Lee,Jung-Soo Lee,Youn-Suk Lee,Dae-Sung Chung 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-