http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Chung, S.,Park, C. W.,Shin, S. J.,Lim, J. H.,Chung, H. W.,Youn, D.-Y.,Kim, H. W.,Kim, B. S.,Lee, J.-H.,Kim, G.-H.,Chang, Y. S. Oxford University Press 2010 Nephrology, dialysis, transplantation Vol.25 No.2
<P>Obesity has been strongly associated with the development and aggravation of hypertension and chronic kidney disease. To date, the systemic renin-angiotensin system (RAS) has been known to involve in obesity-induced tissue damage and hypertension. However, the intrarenal mechanism whereby obesity induces and aggravates hypertension and renal disease remains poorly understood. Therefore, we investigated the role of intrarenal RAS and oxidative stress in diet-induced hypertension and renal inflammation in spontaneously hypertensive rats (SHR) fed a high-fat diet.</P>
Park, J.J.,Chae, I.H.,Cho, Y.S.,Kim, S.W.,Yang, H.M.,Seo, J.B.,Kim, S.Y.,Oh, I.Y.,Yoon, C.H.,Suh, J.W.,Park, K.W.,Chung, W.Y.,Youn, T.J.,Choi, D.J.,Kim, H.S. Elsevier 2012 JACC. Cardiovascular interventions Vol.5 No.8
Objectives: This study sought to investigate the extent of and factors related to lumen and vessel area change in coronary arteries after total occlusion (TO) recanalization. Background: TO of a coronary artery promotes negative remodeling in distal reference segments. Recanalization can restore blood flow, potentially leading to positive vascular remodeling. Methods: From March 2005 to June 2008, 58 consecutive patients with de novo TO lesions of at least 1-month duration were enrolled. We performed intravascular ultrasound after successful percutaneous coronary intervention and at the 6-month follow-up, and we quantified changes in the distal reference segments. Results: At the 6-month follow-up, there was a significant increase in the mean lumen diameter (+0.21 mm, p = 0.001), the mean external elastic membrane diameter (+0.13 mm, p = 0.010), the lumen area (+0.87 mm<SUP>2</SUP>, p < 0.001), and the external elastic membrane area (+0.85 mm<SUP>2</SUP>, p = 0.001) in the distal reference segments and an increase in the left ventricular ejection fraction (+2.77%, p = 0.010). Overall, 40 of 58 patients (69%) showed lumen area increase; these patients had increase in lumen diameter by 0.40 +/- 0.34 mm (p < 0.001) and increase in incomplete stent apposition rate (p = 0.006). A TO duration of longer than 3 months (odds ratio [OR]: 14.8; 95% confidence interval [CI]: 1.28 to 172.8, p = 0.032), a poor collateral flow (OR: 12.0; 95% CI: 1.92 to 74.2, p = 0.008), and statin use (OR: 7.4; 95% CI: 1.03 to 53.6, p = 0.047) were independent predictors of lumen area increase. Conclusions: Recanalization of TO led to lumen area increase in two-thirds of the patients. Independent predictors of lumen area increase were occlusion duration, a poor collateral flow, and statin use. These factors could be used as guides in choosing the optimal stent size during percutaneous coronary intervention to TO lesions and optimal medical therapy during follow-up.
Treatment outcomes of 70 cases of early esophageal carcinoma: 12 years of experience
Kim, J.-H.,Chung, H. S.,Youn, Y. H.,Park, S. W.,Song, S. Y.,Chung, J. B.,Kim, C. B.,Lee, Y. C. Blackwell Publishing Asia 2007 Diseases of the esophagus Vol.20 No.4
<P>SUMMARY. </P><P>Early esophageal cancer (EEC) has an excellent prognosis compared to advanced esophageal cancer. Nowadays, endoscopic mucosal resection (EMR) may offer another alternative to cure early cancers of the gastrointestinal tract. We aimed to evaluate the clinical outcomes of EEC in Korea after curative treatments; EMR or surgery. We retrospectively reviewed the medical records of patients diagnosed as EEC from January 1994 to August 2005 at Yonsei University Medical Center, Seoul, Korea. Among 888 patients diagnosed with esophageal cancer, 70 (7.9%) were included as EEC. Among them, 10 patients (14.3%) were treated by EMR, and 50 (71.4%) by operation. The treatment outcomes of EEC in relation to various clinicopathologic factors along with survival rates were analyzed. There were 18 cases (30%) of mucosal lesions and 42 cases (70%) of submucosal lesions. Overall 5-year survival rate was 84.3%. When comparing treatment outcomes between EMR-treated and operated groups, there were no significant differences in complete remission (80%<I>vs.</I> 84%), recurrence (20%<I>vs.</I> 16%) and 5-year survival rate (100%<I>vs.</I> 78.3%). EEC is a potentially curable entity with a good clinical prognosis. EMR can be considered as another treatment arm for EEC, along with surgical resection.</P>
Distinctive pattern of white matter injury in neonates with rotavirus infection
Yeom, J. S.,Kim, Y.-S.,Seo, J.-H.,Park, J. S.,Park, E. S.,Lim, J.-Y.,Woo, H.-O.,Youn, H.-S.,Choi, D. S.,Chung, J.-Y.,Han, T.-H.,Park, C.-H. Ovid Technologies (Wolters Kluwer) - American Acad 2015 Neurology Vol.84 No.1
<P>To report a consecutive series of neonates with seizures or apnea and displaying white matter injuries with distinctive magnetic resonance diffusion-weighted imaging (DWI) pattern, and to discuss the high positive rate of rotavirus infection seen in these patients.</P>