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      • SCOPUSKCI등재

        Family Origin Names and Haplotypes of Y - DNA in Korean Population

        Kim, Jong Soon,Kim, Yung Jin,Ahn, Gwang Sook,Lee, Ju Won,You, Sun Ah 한국유전학회 1996 Genes & Genomics Vol.18 No.4

        The use of restriction fragment length polymorphisms (RFLPs) has been proposed for the construction of a human genetic linkage map and also become a powerful tool in human population genetics. Human Y-chromosome which is haploid and paternally inherited is valuable for investigating male-mediated gene flow and for complement maternally based studies of mtDNA. We have studied 166 samples from 4 kinds of family origin names such as Kyungju Kim, Kimhae Kim, Chunju Lee and Milyang Park based on the 49aTaq 1 polymorphisms, and a total of 25 haplotypes were observed. The B, F, and I bands is observed in all haplotypes and haplotype showing A3, B, D2, D3, F, and I bands is common haplotype except for Chunju Lee. The result obtained are summarized as follows.

      • KCI등재후보

        조기 혈액투석 및 Ethanol 투여로 후유증없이 회복된 Methanol 중독 1 예

        이종호,정숙향,이홍규,김종호,이수진,김종유 대한내과학회 1994 대한내과학회지 Vol.47 No.1

        Methanol is widely used as a industrial agent Clinical manifestations of methanol intoxication include various gastrointestinal symptoms, blindness, coma and death. The lethal dose of methanol in human was reported as 5~200 gm. We report a case of methanol intoxication with peak plasma methanol concentration of 311.6 mg/ dl completely recovered without sequele by early application of hemodialysis, ethanol administration and other supportive measures.

      • Reduction of Spreading Thermal Resistance Using Vapor Chamber Heat Pipe

        You-Seop Lee(이유섭),Jongseok Kim(김종석) 대한기계학회 2010 대한기계학회 춘추학술대회 Vol.2010 No.11

        This paper studies heat spreading aspect of a vapor chamber for chip cooling application. The vapor chamber is a flat-plate heat pipe which can be embedded in the base of a heat sink to reduce the spreading thermal resistance. The thermal behavior of the vapor chamber with acetone as working fluid and micro grooves for wick structure has been experimentally investigated. The employment of the vapor chamber could make the junction temperature of the chip decrease up to 10 K with a reduction of spreading thermal resistance of 0.4 K/W. Such a thermal spreading effect depends on the area ratio of the vapor chamber and heating element. A spreading thermal resistance analysis is performed using Lee's closed form correlation to estimate the spreading capability of the vapor chamber. The thermal behavior of the vapor chamber is also numerically studied using in a good agreement with the junction temperature measurement results.

      • 다공질규소 PL의 온도의존성 해석

        이기원,박선화,김영유,안은준 公州大學校 基礎科學硏究所 2004 自然科學硏究 Vol.11 No.-

        본 연구에서는 다공질규소의 온도를 상온에서부터 10K까지 감소시키면서 PL스펙트럼을 측정하여 PL의 온도의존성을 관찰하였다. 그 결과를 Lee가 제안한 세 가지 발광원인에 대한 에너지띠구조 모형을 도입하여 해석하였다. 그 결과 다공질규소 PL의 온도의존성은 Lee가 제안한 세 가지 발광원인이 규소화합물에 의한 발광, 계면에서의 발광, 양자구속효과에 의한 발광이라고 할 때 만족하게 설명되었다. In this research, we investigated temperature dependence of photoluminescence characteristics of porous silicon in temperature ranges from room temperature to 10K. the results, we analyzed it introduce electronic band structures suggest by Lee et al. It is about that three different luminescence origins. From results, we found that temperature dependence of porous silicon photoluminescence were explained properly when electronic band structure of three different luminescence origins is based on the chemical model and the interface region model and the quantum confinement model.

      • SEAWEED EXTRACTS AS A POTENTIAL TOOL FOR THE ATTENUATION OF OXIDATIVE DAMAGE IN OBESITY‐RELATED PATHOLOGIES

        Lee, Ok‐,Hwan,Yoon, Kye‐,Yoon,Kim, Kui‐,Jin,You, SangGuan,Lee, Boo‐,Yong Blackwell Publishing Ltd 2011 Journal of phycology Vol.47 No.3

        <P>Recent studies suggest that seaweed extracts are a significant source of bioactive compounds comparable to the dietary phytochemicals such as onion and tea extracts. The exploration of natural antioxidants that attenuate oxidative damage is important for developing strategies to treat obesity‐related pathologies. The objective of this study was to screen the effects of seaweed extracts of 49 species on adipocyte differentiation and reactive oxygen species (ROS) production during the adipogenesis in 3T3‐L1 adipocytes, and to investigate their total phenol contents and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) radical scavenging activities. Our results show that high total phenol contents were observed in the extracts of <I>Ecklonia cava</I> (see Table?1 for taxonomic authors) (681.1 ± 16.0 μg gallic acid equivalents [GAE] · g<SUP>−1</SUP>), <I>Dictyopteris undulata</I> (641.3 ± 70.7 μg GAE · g<SUP>−1</SUP>), and <I>Laurencia intermedia</I> (560.9 ± 48.1 μg GAE · g<SUP>−1</SUP>). In addition, DPPH radical scavenging activities were markedly higher in <I>Sargassum macrocarpum</I> (60.2%), <I>Polysiphonia morrowii</I> (55.0%), and <I>Ishige okamurae</I> (52.9%) than those of other seaweed extracts (<I>P </I><<I> </I>0.05). Moreover, treatment with several seaweed extracts including <I>D. undulata</I>, <I>Sargassum micracanthum</I>, <I>Chondrus ocellatus</I>, <I>Gelidium amansii</I>, <I>Gracilaria verrucosa</I>, and <I>Grateloupia lanceolata</I> significantly inhibited adipocyte differentiation and ROS production during differentiation of 3T3‐L1 preadipocytes. Furthermore, the production of ROS was positively correlated with lipid accumulation (<I>R</I><SUP>2</SUP> = 0.8149). According to these preliminary results, some of the seaweed extracts can inhibit ROS generation, which may protect against oxidative stress that is linked to obesity. Further studies are required to determine the molecular mechanism between the verified seaweeds and ROS, and the resulting effects on obesity.</P><tabular xml:id='t1'><P><B>  List of Korean seaweed extracts of 49 species evaluated in this experiment. </B></P><table frame='topbot'><tgroup cols='5' align='left'><colspec colname='col1' colnum='1'/><colspec colname='col2' colnum='2'/><colspec colname='col3' colnum='3'/><colspec colname='col4' colnum='4'/><colspec colname='col5' colnum='5'/><thead valign='bottom'><row rowsep='1'><entry>Type</entry><entry>No.</entry><entry align='center'>Scientific name</entry><entry align='center'>Collection time</entry><entry>TP<SUP>1</SUP> (μg GAE · g<SUP>−1</SUP>)</entry></row></thead><tbody valign='top'><row><entry morerows='27' valign='top'>Brown macroalgae</entry><entry>SE‐1</entry><entry> <I>Chondracanthus tenellus</I> (Harv.) Hommers.</entry><entry>April 27, 2006</entry><entry>112.8 ± 15.1<SUP>lm</SUP></entry></row><row><entry>SE‐2</entry><entry> <I>Colpomenia sinusa</I> (F. C. Mertens ex Roth) Derbes et Solier in Castagne</entry><entry>May 11, 2006</entry><entry>44.0 ± 4.1<SUP>opqrs</SUP></entry></row><row><entry>SE‐3</entry><entry> <I>Dictyopteris divaricata</I> (Okamura) Okamura</entry><entry>April 6, 2006</entry><entry>41.5 ± 5.6<SUP>pqrs</SUP></entry></row><row><entry>SE‐4</entry><entry> <I>Dictyopteris pacifica</I> (Yendo) I. K. Hwang, H.‐S. Kim et W. J. Lee</entry><entry>April 27, 2006</entry><entry>80.9 ± 8.3<SUP>mno</SUP></entry></row><row><entry>SE‐5</entry><entry> <I>Dictyopteris prolifera</I> (Okamura) Okamura</entry><entry>November 26, 2007</entry><entry>48.4 ± 3.0<SUP>nopqrs</SUP></entry></row><row><entry>SE‐6</entry><entry> <I>Dictyopteris undulata</I> Holmes</entry><entry>July 28, 2007</entry><e

      • SCIESCOPUSKCI등재

        Metagenomic Analysis of Fungal Communities Inhabiting the Fairy Ring Zone of Tricholoma matsutake

        ( Miae Kim1 ),( Hyeok Jun Yoon ),( Young Hyun You ),( Ye Eun Kim ),( Ju Ri Woo ),( Yeong Gyo Seo ),( Gyeong Min Lee ),( Young Ja Kim ),( Won Sik Kong ),( Jong Guk Kim ) 한국미생물 · 생명공학회 2013 Journal of microbiology and biotechnology Vol.23 No.10

        Tricholoma matsutake, an ectomycorrhiza that has mutual relationships with the rootlet of Pinus denisflora, forms a fruiting body that serves as a valuable food in Asia. However, the artificial culture of this fungus has not been successful. Soil fungi, including T. matsutake, coexist with many other microorganisms and plants; therefore, complex microbial communities have an influence on the fruiting body formation of T. matsutake. Here, we report on the structures of fungal communities associated with the fairy ring of T. matsutake through the pyrosequencing method. Soil samples were collected inside the fairy ring zone, in the fairy ring zone, and outside the fairy ring zone. A total of 37,125 sequencing reads were obtained and 728 to 1,962 operational taxonomic units (OTUs) were observed in the sampling zones. The fairy ring zone had the lowest OTUs and the lowest fungal diversity of all sampling zones. The number of OTUs and fungal taxa inside and outside the fairy ring zone was, respectively, about 2 times and 1.5 times higher than the fairy ring. Taxonomic analysis showed that each sampling zone has different fungal communities. In particular, out of 209 genera total, 6 genera in the fairy ring zone, such as Hemimycena, were uniquely present and 31 genera, such as Mycena, Boletopsis, and Repetophragma, were specifically absent. The results of metagenomic analysis based on the pyrosequencing indicate a decrease of fungal communities in the fairy ring zone and changes of fungal communities depending on the fairy ring growth of T. matsutake.

      • 한국형 가정보육시설의 디자인지침 개발을 위한 이론적 고찰

        이유미(You-Mi Lee),김미희(Mi-Hee Kim) 전남대학교 생활과학연구소 2005 生活科學硏究 Vol.15 No.-

        Family day care centers in apartment complexes, which are popular in Korea, have merits as day care centers for young children due to their homey environments, closeness to children’s homes, and available outdoor playgrounds utilizing open space in the complexes. Thus, there is a great potential to develop a design guideline for family day care in apartments which are in demand now. The purpose of this study is to provide basic information for developing a design guideline for family day care centers. Therefore, this study aimed to investigate the important issues that influence the development of design family day care center. These issues are environment behavior. Murtha & Lee’s User Benefit Criteria, and Pattern theory. As a result, this study provides basic data for developing a design guideline for family day care and as a base for the next study.

      • 비만 여성을 대상으로 한 해조류 추출물의 국부처치와 운동 병행을 통한 지방분해 효과의 임상적 검정

        서태수,이인숙,변재철,김규호,박승한,김유영,김상국,김현정,김상기,신동철,성미영,박종석,김종기,박언휘 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.3

        This study was carried out to test the body fat breakdown during topical seaweed extract treatment and in combination with the aerobic exercise. Of 20 female obesity subjects, ten treated a cream types of seaweed extract(control group) and ten treated a placebo cream(placebo group). Topical treatment of each sample was designed for 4 weeks, and treated with 2 times a day about 10ml on the abdomen and the thigh, respectively. All subjects were participated aerobic dance half hour a day and four times a week. After 4 weeks of topical treatment and exercise, they were measured body fat, skinfold thickness, body circumference. Then venous blood samples were taken and analyzed blood cells, serum enzymes, and serum lipids. There were reduction of body weight, % of body fat, antebrachium, brachium, chest, waist, thigh circumference and abdomen thickness between pre and post treatment in both group. Especially, body weight and % of body fat significantly reduced in the subjects treating the seaweed extract than those treating the placebo. There were significant decrement in total cholesterol and LDL whereas increment in HDL and TBIL in the control group, but no significant difference in the placebo group. In conclusion, there were 7.6% of body fat reduction during 4 weeks of aerobic exercise and 21% of body fat reducement in combination of topical seaweed treatment and exercise, respectively. These results suggest that the topical treatment of seaweed extract should be very effective for fat breakdown. Especially, the body fat breakdown maximized in the combination with the topical seaweed extracts treatment and the aerobic exercise.

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