축구선수의 Detraining과 Retraining이 혈청지질 및 호르몬농도에 미치는 영향

정정화,박재현,채종훈,성혜련,황지인,윤미숙,노금선,윤종관,윤영학,노순덕,정경숙,박일규,김은희,박현태,박상갑 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1

The purpose of this study was to investigate the effects of detraining and retraining on serum lipid and hormones in soccer players. Subjects were seven male high-school soccer players. V˙O_2max was determined for each subjects by administering a treadmill test(initial speed: 90m/min, grade: 5%, increasing speed per 3 min: 30m/min). Serum lipid(T-C, TG, HDL-C LDL-C) and hormones(epinephrine, norepinephrine, growth hormones, cortisol) were assayed pre and post detraining in 10, 20, 30 days after retraining. The repeated ANOVA was used to determine significant differences. The 0.05 level of significance was as critical level for the study. The results of the study were as follows: 1. V˙O_2max(ml/min) were 3576.3±204.2ml/min pre detraining, 3234.1±198.9 ml/min post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/min) were 3601.4±170.9 ml/min. There were significantly(p<.05) increased in retraining periods. 2. V˙O_2max(ml/kg/min) were significantly(p<.05) decreased from 62.3±2.9 ml/kg/min to 55.9±4.7 ml/kg/min in detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/kg/min) were 62.4±3.4ml/kg/min, 62.7±2.3ml.kg/min, 67.3±7.2ml/kg/min respectively. There were significantly(p<.05) increased in retraining periods. 3. T-C were significantly (p<.05) increased from 166.6±8.5mg/dl to 175.3±10.3 mg/dl in detraining. In 10, 20, 30 days after retraining, T-C were 160.1± 3.2mg/dl, 156.7±3.7mg/dl, 140.3±9.0mg/dl. There were significantly(p<.05) decreased in retraining periods. 4. HDL-C were 61.4±6.6mg/di pre detraining, 5.3±6.6mg/dl post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, HDL-C were 56.9±7.1mg/dl, 56.4±9.2mg/dl, 57.7±9.1mg/dl respectively. There were no significant difference in retraining periods. 5. The hormones(epinephrine. norepinephrine, growth hormone, cortisol) were changed as same patterns. Epinephrine were 26.0±7.0[g/ml pre detraining, 24.6±3.2pg/ml post detraining. In 10, 20, 30 days after retraining, epinephrine were 26.9±5.6pg/ml, 30.6±6.2pg/ml, 29.4±5.6pg/ml respectively. There were no significant difference in retraining periods. In conclusion, HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were decreased, T-C, LDL-C and TG were increased in detraining. But HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were increased, T-C, LDL-C and TG were decreased in retraining.

Insulin resistance mediates high-fat diet-induced pulmonary fibrosis and airway hyperresponsiveness through the TGF-β1 pathway

Park, Yoon Hee,Oh, Eun Yi,Han, Heejae,Yang, Misuk,Park, Hye Jung,Park, Kyung Hee,Lee, Jae-Hyun,Park, Jung-Won Nature Publishing Group UK 2019 Experimental and molecular medicine Vol.51 No.5

<▼1><P>Prior studies have reported the presence of lung fibrosis and enhanced airway hyperresponsiveness (AHR) in mice with high-fat-diet (HFD)-induced obesity. This study evaluated the role of TGF-β1 in HFD-induced AHR and lung fibrosis in a murine model. We generated HFD-induced obesity mice and performed glucose and insulin tolerance tests. HFD mice with or without ovalbumin sensitization and challenge were also treated with an anti-TGF-β1 neutralizing antibody. AHR to methacholine, inflammatory cells in the bronchoalveolar lavage fluid (BALF), and histological features were evaluated. Insulin was intranasally administered to normal diet (ND) mice, and in vitro insulin stimulation of BEAS-2b cells was performed. HFD-induced obesity mice had increased insulin resistance, enhanced AHR, peribronchial and perivascular fibrosis, and increased numbers of macrophages in the BALF. However, they did not have meaningful eosinophilic or neutrophilic inflammation in the lungs compared with ND mice. The HFD enhanced TGF-β1 expression in the bronchial epithelium, but we found no differences in the expression of interleukin (IL)−4 or IL-5 in lung homogenates. Administration of the anti-TGF-β1 antibody attenuated HFD-induced AHR and lung fibrosis. It also attenuated goblet cell hyperplasia, but did not affect the AHR and inflammatory cell infiltration induced by OVA challenge. The intranasal administration of insulin enhanced TGF-β1 expression in the bronchial epithelium and lung fibrosis. Stimulating BEAS-2b cells with insulin also increased TGF-β1 production by 24 h. We concluded that HFD-induced obesity-associated insulin resistance enhances TGF-β1 expression in the bronchial epithelium, which may play an important role in the development of lung fibrosis and AHR in obesity.</P></▼1><▼2><P><B>Obesity: A trigger for asthma onset</B></P><P>Insulin resistance may be an important causative factor underlying the increased risk of asthma and other respiratory issues in obese individuals. Obesity doubles the likelihood of developing asthma, with symptoms that are more difficult to control than in non-obese patients. The connection between these conditions is poorly understood, but researchers led by Jung-Won Park, Yonsei University College of Medicine, Seoul, South Korea, have identified a potential mechanism. They demonstrated that a signaling molecule called TGF-β1 contributes to airway sensitivity and tissue scarring in a mouse model of diet-induced obesity. Subsequent experiments showed that treatment with insulin also gives rise to increased TGF-β1 production in the mouse lung. Since insulin resistance is a common feature of obesity, resulting in abnormally high levels of circulating insulin, this could also account for the increased risk of respiratory problems.</P></▼2>

급성전골수성백혈병에서 백혈구성분채집술에 이은 치명적인 뇌출혈 2예

오윤정,박소윤,김윤정,한동석,김현수,최진혁,남동기,임호영,김효철,주희재 아주대학교 의과학연구소 1998 아주의학 Vol.3 No.1

The aim of this study is to report 2 cases of acute promyelocytic leukemia who died from intracranial hemorrhage following leukapheresis and to provide proper preventive measures against hemorrhage following leukapheresis. From 1994 to 1997, a total of twenty-six patients with leukemia underwent leukapheresis to control hyperleukocytosis at Ajou University Hospital. Two patients with acute promyelocytic leukemia received all-trans retinoic acid but developed drug-induced hyperleukocytosis. Shortly after leukapheresis, they died from intracranial hemorrhage. The risk factors for fatal hemorrhage are thought to be coexisting disseminated intravascular coagulation(DIC), thrombocytopenia aggravated by leukapheresis, exacerbated coagulopathy related to mechanical trauma through leukapheresis and the excess use of citrate during leukapheresis. To reduce the risk of the bleeding associated with leukapheresis, it is necessary to replace platelet sufficiently before and after leukapheresis and to give calcium to correct coagulopathy induced by excess citrate which is used as anticoagulant as well as the correction of disseminated intravascular coagulation.

ATHB12, an ABA-lnducible Homeodomain-Leucine Zipper (HD-Zip) Protein of Arabidopsis, Negatively Regulates the Growth of the Inflorescence Stem by Decreasing the Expression of a Gibberellin 20-Oxidase Gene

Ora Son,허윤선,김윤경,이현정,김성한,김미란,남경희,이명석,김부용,박종범,박정안,이석찬,Atsushi Hanada,Shinjiro Yamaguchi,이인정,김승기,윤대진,Eva So¨derman,천충일 Sookmyung Women's University Research Institute of 2010 여성과 건강 Vol.6 No.1

워터스, 파노라마 방사선사진과 Scanora 방사선사진의 상악동 점막비후 진단 결과의 비교

윤숙자,강병철,정현대 大韓口腔顎顔面 放射線學會 1995 Imaging Science in Dentistry Vol.25 No.2

The purpose of this study was to compare the diagnostic performance of Waters' and panoramic view ; maxillary sinus posteroanterior and lateral scanography of ?? for mucosal thickening of maxillary sinus as well as to identify the utility of ?? for the detection of maxillary sinus disease. The assessment was done at 66 maxillary sinuses in 45 patients and the results were as follows ; 1. Estimation of presence or absence of mucosal thickening. The sensitivity, specificity, and positive and negative predictive value of maxillary sinus posteroanterior and lateral scanography were 0.865, 0.860, 0.921, and 0.805 respectively and slightly higher than those of Waters' and panoramic views, which were 0.832, 0.835, 0.903, and 0.728 respectively. However, paired t-test showed no significant differences in the diagnostic performance of the two pairs of imaging modalities. 2. Estimation of the types of mucosal thickening. The diagnostic accuracy for type Ⅰ, Ⅱ, Ⅲ was 75.3% on Waters' and panoramic view ; 77.9% on maxillary sinus posteroanterior and lateral scanography. It was higher on the latter, but showed no significant differences from that on the former. 3. Reliability of interpretation. In intraobserver and interobserver agreement, both overall rates of agreement and kappa-value were slightly higher on maxillary sinus posteroanterior and lateral scanography than on Waters' and panoramic views. There was no significant differences between the two pairs of imaging modalities. These results suggested that scanogram is a useful diagnostic radiography as well as Waters' and panoramic views for detection of maxillary sinusitis.

콜리플라워를 이용한 피클제조 최적화

정현아,윤지영,황재선,주나미 한국식생활문화학회 2004 韓國食生活文化學會誌 Vol.19 No.2

The purpose of this study was to determine the organoleptic characterisitcs of cauliflower pickles made in various compounding ratio according to central conposite design for optimum organoleptic characteristics of the cauliflower pickles. The optimum mixing condition of cauliflower pickles were optimized, using central composite design with 3 variables and 3 levels, by response surface methodology. The various kinds of cauliflower pickle were made in various compounding ratio of vinegar, salt and sucrose - critical ingredients of pickle recipe - and were presented to reliable panels, who graded the subjects in 7 degrees for 4 items : color, lavor, hardness and overall quality. The optimum mixing conditions of cauliflower pickle were 603.50g of vinegar, 80.13g of salt and 251.079 of sucrose in the maximum point of overall quality.

레이저 스페클간섭법에 있어서 스페클크기와 측정 한계에 관한 연구

윤성운,김경석,양승필,정현철,김정호,이도윤 한국공작기계학회 1996 한국생산제조학회지 Vol.5 No.1

The high coherence of laser beam has made it possible to observe interference effects even in the light scattered from rough surfaces. That's why, when object with a scattering surface is illuminated with laser light, we do see a speckled appearance due to random interference. This sort of unique property of laser speckle has brought into existence the new noncontacting techniques such as speckle metrology method of measuring deformation, displacement, and vibration etc of objects with high optical sensitivity. The measurable range of speckle metrology especially used to measure in-plane information, however, is limited by some factors, the so-called strain, rotation, tilt of surface and out of displacement perpendicular to the plane of analysis. This restrictions severly limits the measurable range of speckle metrology by causing the decorrelation of speckle patterns. It is the purpose of this paper to give a survey on the measurable limitation of speckle photography method that is one of speckle metrology. Namely we will discuss the mutual relationships and problems of each limitations adding the restriction of the largest and smallest displacement measurable with speckle methods.

새로운 상감도자기 기법을 이용한 특산품 개발

윤상옥,박정근,윤종호,이학현 강원대학교 석재복합신소재제품연구센터 2001 석재연 논문집 Vol.6 No.-

새로운 상감도자기 기법을 이용한 특산품은 개발하기 위하여 지르코니아와 백토 및 황토계 소지에 대한 선 수축과 색의 변화를 조사하였다. 지르코니아계는 1350℃ 소결에서 23%정도의 선수축율을 나타내고 첨가량은 0.5wt% 이내가 적당하며, Co3O4는 청색, NiO는 녹색, Fe2O3는 갈색 그리고 Mn3O4는 검정색으로 변하였다. 백토계는 1250℃ 소결에서 13%정도의 선수축율을 나타내고 첨가량은 1wt%이내가 적당하며, NiO는 갈색, Co3O4는 녹색, TiO2는 아이보리색으로 변화 하였다. 황토계는 1250℃ 소결에서 12.5%정도의 선수축율을 나타내며, TiO2는 노란색, 그리고 복합첨가의 경우 검정색으로 변화하였다. 첨가된 전이금속산화물은 제2상의 화합물을 형성하여 분산되어 존재함으로써 발색시키는 것으로 판단된다. 상감도자기 시작품은 색채가 우아하고 질감이 좋아 특산품으로 활용가능성이 매우 높은 것으로 판단된다. Variation of sintered color and linear shrinkage in zirconia, white clay and yellow clay systems have been investigated with various transition metal oxide additives to develop special products using new inlaid porcelain method. Zirconia systems sintered at 1350℃ show 23% of linear shrinkages and their additives are suitable to add up to 0.5wt%, and the color of their specimens changes from white to blue for Co3O4, green for NiO, brown for Fe2O3 and black for Mn3O4, respectively. White clay systems sintered at 1250℃ appear about 13% of linear shrinkages and their additives are suitable to add up to 1wt%, and the color of their specimens changes form white to brown for NiO, to blue for Co3O4, green for Cr2O3 and ivory for TiO2, repedtively. Yellow clay systems sintered at 1250℃ show about 12.5% of linear shrinkages and the color of their specimens changes from red to yellow for TiO2 and black for complex compounds, respectively. It could be explained due to the formation of the second phase compounds by added transition metal oxides with basic composition and the dispersion of their second phase particles in sintered bodies.

에탄 분자의 적외선 스펙트럼의 이론적 합성

鄭玹采,윤대현,임화준,김기선 慶熙大學校 1987 論文集 Vol.16 No.-

The ν_6 band of the ethane gas molecule was theoretically synthesized. The intensity and the frequency of each rotational line were computed with VAX-11 computer. The theoretically synthesized spectrum was compared with the experimentally obtained spectrum, which was taken through FT-IR spectrophotometer MX-3600. The R and P branches of the ν_6 band contour of the ethane gas molecule were different from the regular symmetrie top molecule and rather similar to the linear molecules as if there were no K dependence. The absorbance of the P-branch spectrum was overlapped by the unknown branches of the neighbour bands The intensities and frequencies of the unknown lines were not indentified. The overall band contour of the observed spectrum was quite well coincided with the theoretical spectrum except the P-branch.

가네트를 활용한 고강도 콘크리트의 황산염저항성 특성 연구

윤종문,윤요현,박정민,김화중 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

The purpose of this study is about to characteristic of sulfate resist performance following precipitation age of high strength concrete using the garnet minute power. Experiment was compared to the weight change and compressive strength to follow that unit water content 160kg/m³, W/B 30%, 35% and fine aggregate ratio(S/A) 40%, 42%, 44%, admixture(garnet minute power. fly ash) 0%, 10%, 20% and precipitation age. We got the conclusion of the downside through the experiment. Garnet concrete was appeared that was superior to sulfate resist performance by the increasing of garnet. Case of the W/B 30%. garnet concrete did not get up the diminution of weight to follow that small mixing ratio of S/A and expressed diminution of weight the increasing in ratio of S/A. Consequently. If we should make concrete as condition of optimum mixture. we will be expected the effect of sulfate resist performance.