색소성 담마진의 피진형 1예

전경준,김용환 순천향의과대학 1978 Journal of Soonchunhyang Medical Science Vol.1 No.1

Urticaria pigmentosa is the most common form of mastocytosis and is a general term applied to local and systemic accumulations of mast cells. A case of urticaria pigmentosa is a 48 years old male patient with rather typical cutaneous manifestations, is presented with a review of the literature. Presenting symptoms on admisson were hyperpigmented maculo-papular eruptions on entire skin surface except face and general weaknees and pruritus approximately 6 months durations. Physical findings referable to urticaria pigmentosa were cutaneous lesions with positive Darier's sign. Laboratory data and roentgenogram of the chest showed non specific fidings but diverticulum on middle portion of the esophagus. Biopsy findings of the affected skin & muscle supported the clinical diagnosis of urticaria pigmentosa. He had no evidence of suspected lesions of malignancy. He had been placed on steroid therapy and other symptomatic measures without remarkable improvement.

한국인에서 Lipoprotein lipase gene polymorphism의 빈도와 혈관질환과의 관계

정준용,박소영,김제,성인환,김영건,전은석 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

Background : Lipoprotein lipase(LPL) is a key enzyme in the metabolism of serum triglycerides(TG) which is utilized in the peripheral tissue as free fatty acid and stored in adipose tissue. LPL gene is consisted of 10 exons which encode 475 amino acids and over 9 LPL gene polymorphisms have been reported. It's polymorphisms are related to the lipid levels and the severity of atherosclerosis in the coronary artery disease. In Korea, LPL polymorphisms has not been reported yet. This study is purposed on the incidences of LPL gene mutations and on it's relationships with blood lipid levels and the severity of atherosclerosis. Methods : Our subjects were consisted of three groups, normal controls(n=50), coronary artery disease(CAD, n=51) and cerebrovascular disease(CVD, n=52). The PCR amplified genomic DNA from peripheral white blood cell were analyzed with restriction fragment length polymorphisms (RFLP by two different restriction enzyme(PVU II, Hind III). Results : Total cholesterol(TC) were higher in CVD than in controls and in CAD (203±60mg/ dl vs 188±37, 167±42, p<0.01). Triglyceride(TG) were also elevated in CAD(166±65mg/dl vs 122±62 in controls, p<0.05). HDL cholesterol(HDL-C) were higher in controls than in CVD and CAD(49±9mg/dl vs 36±10, 44±9, p<0.05). The incidences of Hind III RFLP and PVU II RFLP has no differences among groups. Only HDL-C was elevated in Hind III RFLP(-/-) homozygotes. Conclusions : The LPL gene mutations in intron 6 and 8 have no direct effects on the lipid profiles and the severity of coronary artery disease. Although LPL is a key enzyme in TG metabolism, two mutations in this study could not change the activity of LPL, nor were not a marker of linked other site mutations. The mutation(s) in exon which encode amino acid for enzyme activity should be detected to analyze the pathophysiology of the atherogenesis.

Liver-Fluke의 寄生이 山羊의 繁殖障害와 乳肉生産에 미치는 影響에 관한 硏究

金敎準,田暢淇,金容國,金相根 충남대학교 농업과학연구소 1979 農業技術硏究報告 Vol.6 No.1

These studies were carried out to investigate the effects of liver-fluke infection on the reproductive disorder and milk and meat production in Korea Native Goat. A survey of infected goat in Chungnam district was conducted with 474 head by interdermal reaction and also a clinical observation was founded. A experiment was carried out to determine the effects of liver fluke extract on the reproductive disorder by subcutaneous injection and milk and meat yield were measured from treated goats. The results obtained were summarized as follows. 1. The rate of positive goat was 71.3% among the surveyed goat and the highest rate was appeared at 3∼4 years old goats as 81.4%. 2. The treated goats lost condition and failed to thrive, and became progressive weaker. 3. In hemogram observation, the rate of eosinophil leucocyte was increased significantly by extract treated. 4. It was appeared the pathogenic signs such symptoms poisoning liver function disturbance and reproductive disorder from treated goats with liver fluke extract. 5. In milking goat the milk yield droped significantly and fattening goat did not fatten. 6. The gross income value per capita was lower from infected goat and it was analysed more sensitivly in net income value.

충남대학교 학술림 산책로 훼손실태 및 관리방안에 관한 연구

이준우,김명준,최윤호,전용준,오도교,김민호,이소연,이경형 충남대학교 농업과학연구소 2004 농업과학연구 Vol.31 No.2

This study concentrates an the trail of the CNU(Chungnam National University) forest. The amount of use and the pattern of damage are considered, as well as the extent of environmental damage. Finally, some managerial strategies are proposed in connection with sustainable maintenance. The trail of the university forest is composed of three sections; one is the neighborhood park and the Institute of Information Technology/Communications, the second is the Institute of Information Technology/Communications and the Dormitory, and the third section is the Dormitory and the Foreign prof's Apt. The total length of the trail is 2.6km. The daily amount of use is 1,269 visitors per day. The amount of using increased three times the amount of that in 1998. This study shows the pattern of damage of the trail in the order of root-exposure, widening, rock-exposure, deepening and the divergence in the frequency of occurrence of all these factors. Environmental damage is also graded thus: grade 3 is 27.4m, grade 4 is 0.8m, grade 5 is 1.5m, and grade 6 is 0.2m. Accordingly, some managerial strategies were proposed in connection with the sustainable trail maintenance.

하악골 골절 환자에 있어 수술후 합병증으로 발생한 골수염의 치험례

윤규호,전인성,신용길,박준호,허남오,방석준 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.4

The term osteomyelitis literally means inflammation of bone marrow. It is described as an inflammatory condition of bone primarily engaging the medullary Following circulatory collapse and ischemia, the involved portions of the bone become necrotic. Cellulitis and osteomyelitis are the most frequent complications of fractures of the mandible and maxilla, because there is an abscessed tooth in the line of fracture. Since most fractures are compound fractures, infection may develop because of contact with oral secretions or outside air. The treatment of chronic osteomyelitis is still under debate. Some authors rely on antibiotics alone, while others advocate combination with surgery. But when infection occurs, establish proper drainage and administer antibiotics. Author treated a case of infected mandibular fracture with mandibular osteotomy, sequestrectomy, iliac bone graft and hyperbaric oxygen therapy, who had suffered suppurative osteomyelitis and mandibular nonunion following the open reduction of the mandibular fracture.

석탄폐석의 흡착능 개발 및 흡착제로의 활용방안 연구

김해숙,한동준,임재명,전은주,최용범,김병욱,강성환,신혜영 강원대학교 석재복합신소재제품연구센터 1997 석재연 논문집 Vol.2 No.-

본 연구는 폐기물의 형태로 현재 산과 계곡에 투기되어 있는 석탄페석을 이용하여 중금속 흡착과 난분해성 COD 및 색도제거 가능성을 검토하고, 간단한 열처리를 통한 흡착능 개발 실험을 위하여 수행되었다. 실험 결과 천연상태의 석탄폐석은 약 20∼30%의 중금속 흡착능을 지니고 있는 것으로 나타났으며, 탄화 공정인 간단한 열처리 만으로도 약 2 ∼ 5배의 흡착능 향상이 이루어졌다. 그리고 석탄폐석의 열처리 조건 변화에 따른 중금속 흡착능 실험에서는 500℃ 에서 6시간 반응시킨 것이 가장 우수하였다. 칼럼실험에 있어 기존의 입상활성탄 보다 처리효율이 저조하나 석탄폐석은 무가공 상태로도 약 30 ∼ 60%의 COD 및 색도를 제거할 수 있었다. 500℃에서 6시간 열처리된 폐석의 컬럼실험에서 생물학적 유출수의 색도 제거에 우수함을 알 수 있었으며, 중금속 및 COD제거에 있어서는 여과 속도에 따라 많은 차이를 보였다. 본 연구에서는 열처리 공정만 적용한 기초 실험이였으나, 석탄폐석의 흡착제 개발의 가능성을 알 수 있었으며, 활성화 공정을 적용할 경우 흡착능은 더욱 향상될 것으로 판단된다. This reaserch aims to remove the heavy metals, NBDCOD, and color using the coal waste. The expermental by heat treatment. was performed to advance the adsorption capacity. The results are as follows ; ⅰ) The coal waste had the adsorption capacity of heavy metals and the rates were in the range of 20 to 30 percents. ⅱ) The heat treatment was the optimum condition that the reaction time was 6 hours at 500 ℃. ⅲ) In the column experimental, non-treated coal waste removed the COD and color in the range of 20 to 60 percents. ⅳ) Heat-treated coal waste showed the high removal rate of the color in biological effluent, but heavy metal and COD removal rates were changed by the filteration rates.

순천향대학교 천안병원에 입원한 로타바이러스 감염 위장관염 환자의 임상양상

최석주,전세윤,김승수,박경배,김용배,박준수 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

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본태성 고혈압환자의 순응도에 관한 연구 IV : 의사개입과 제도개선의 합동효과 Effect of Combined Strategies Provided by Physician and Insurance

유원상,김용균,김준희,최석구,전영빈 인제대학교 1991 仁濟醫學 Vol.12 No.1

본태성 고혈압환자의 순응도 제고를 위하여 채택한 방책중 의사의 단독개입만으로는 13%의 통원탈락율의 개선, 보험급여 제도의 일부개선만으로는 3%의 악화에 비하여 양자 합동으로는 17%의 개선효과를 보았다. 따라서 진료의사의 좀 더 적극적인 개입과 보험급여의 진료일수제한 철폐가 요망된다. One hundred patients with essential hypertension, consecutively and newly diagnosed, were followed up at hypertension clinic of Paik Hospital to evaluate their compliance for 12 months with combination strategies provided by physician's intervention and extended insurance coverage. Rate of drop-out from reserved visit to clinic were 23% at the end of 3 months, 52% at the end of 12 month, which showed decrease, compared with 26%, and 63% respectively of ordinary management. In conclusion, in order to improve patient's compliance, a positive intervention by physician as well as lifting of insurance limitation should be intensified drastically.

Design method for area-efficient and uniform channel DACs

Jeon, Yong-Joon,Jeon, Jin-Yong,Lee, Sung-Woo,Cho, Gyu-Hyeong IEEE 2010 IEEE TRANSACTIONS ON CONSUMER ELECTRONICS - Vol.56 No.2

<P>A current-mode driving scheme has significant advantages over other competing driving method, and the scheme does not require the time-consuming threshold voltage sampling process used in recent voltage-mode driving methods. Design considerations for compact and uniform channel DACs in current-mode AMOLED display data drivers are addressed in detail. Furthermore, an 8 bit area-efficient cascaded-dividing DAC and a 9 bit segmented DAC are designed in accordance with the suggested DAC design method. The presented DACs perform outstandingly when compared in terms of a composite DAC performance that comprises chip area, power consumption, sampling frequency, and DAC bit resolution.</P>

28-Day Oral Toxicity of Cadmium Selenide in Sprague-Dawley Rats

Yong Soon Kim,Moon Yong Song,Jin Sik Kim,Dae Sik Rha,Yong Joon Jeon,Ji Eun Kim,Hyeon Yeol Ryu,Il Je Yu,Kyung Seuk Song 한국독성학회 2009 Toxicological Research Vol.25 No.3

This study was performed to evaluate the toxicity of cadmium selenide for a period of 28 days in Sprague-Dawley rats. Each of 10 healthy male and females rats per group received daily oral administration for 28-day period at dosage levels 30, 300 and 1,000 ㎎/㎏ of body weight. Mortality and clinical signs were checked, and body weight, water intake and food consumption were also recorded weekly. There were no dose-related changes in food consumption or urine volume. All animals survived to the end of study with no clinical signs or differences in body weight gain observed when compared with the control group. At the end of study, all animals including control group, were subjected to necropsy. Blood samples were collected for hematology tests including coagulation time and biochemistry analysis. Blood coagulation time and relative organ weight were unaffected by all received doses. White Blood Cell (WBC) counts significantly increased in the 300 ㎎/㎏ administered male animal group when compared to the control. Monocyte (MO) value were also increased significantly in both 300 and 1,000 ㎎/㎏ male animal group. However, Mean Corpuscular Volume (MCV) were significantly decreased compared with the control in the 1,000 ㎎/㎏ dose groups for male and female animals. Mean Corpuscular Hemoglobin (MCH) decreased significantly for female in the 300 and 1,000 ㎎/㎏ group compared to the control. Blood biochemical values of Inorganic phosphorus (IP) were significantly increased in both the 300 and 1,000 ㎎/㎏ dose groups in male animals when compared to the control. Creatinine (CRE) levels indicated significant increase in kidney function for the female, 30 ㎎/㎏ dose group when compared with control. There was a significant decrease in thymus absolute organ weight in the female, 1,000 ㎎/㎏ dose group when compared with control. Histopathological findings revealed no evidence of injury related to cadmium selenide except for one case of focal hepatic inflammation in the high dose (1,000 ㎎/㎏) group. One case of lung inflammation was also seen in the control group. Basis on these result, the No Observable Adverse Effect Level (NOAEL) of cadmium selenide was determined to be more than 1,000 mg/kg/day for male and female rats under conditions in this study.