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Yoichi Sakakihara(Yoichi Sakakihara ) The Pacific Early Childhood Education Research Ass 2024 Asia-Pacific journal of research in early childhoo Vol.18 No.1
Special Issue: Resilience in Childhood or Resilience and Child Development
( Yoichi Yano ),( Tatsuyuki Tonan ),( Yuriko Koga ),( Toru Nakamura ),( Mitsuhiko Abe ),( Yu Ikezono ),( Michio Sata ),( Takuji Torimura ),( Si Won Lee ),( Mi Hong Choi ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Liver stiffness is sometimes occured in patient with HCV-associated to HIV-positive. Reduction of immune system, the patient might has been got HCV easily. Early detection and treatment should be done to ensure that the patient can be healed. The earlier we can detect, the higher possibility they can be cured. Therefore, nowadays researchers and clinicians focused in the development of diagnostic tools with high sensitivity and specifi city. The noninvasive measurement of liver stiffness (LS) now can be evaluated by transient elastography (fibroScan). Methods: We evaluated 35 patients with chronic viral hepatitis, 69% were male, 31% were female. We divided them into 3 groups, (1) no fi brosis group (2) mild until moderate (3) severe HCV with extensive fi brosis and liver stiffness. All subject (100%) were evaluated by fibroScan, 15 patients (43%) also got liver biopsy, and 31 patients (88%) also got MRI. Study design is cross-sectional with simple random sampling. Results: In TE, the degree of liver fi brosis were calculated by velocity of low-frequency transient wave produced by mechanical-probe. Comparing to liver biopsy, TE has demonstrated both high specifi city and sensitifi ty. The specifi cty of TE is 94.29% to (95%CI: 93.15%-96.7%) and sensitifi ty of TE is 82.85% (95% CI: 79,87%-85,76%). Conclusions: Real-time TE is a reliable surrogate marker of liver fi brosis, with high specifi city and sensitifi ty for early detection in mild fi brosis. However, the applicability of TE is limited to non-obese patients (BMI < 30 kg/m2) and without any ascites. If TE has already predicted liver fi brosis, biposy may not be necessary.
Multiferroic Phase Transitions of Triangular-Lattice-Antiferromagnet RbCoBr3
Yoichi Nishiwaki,Katsunori Iio,Toshiharu Mitsui 한국물리학회 2005 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.46 No.1
An intensive study of dielectric and magnetic properties in RbCoBr3 was performed to confrm the previously observed simultaneous onset of ferroelectric and antiferromagnetic orderings just at the antiferromagnetic transition point. The real part of the dielectric constant as a function of temperature exhibits an in ection point at 37.2 K and two anomalous round and sharp peaks at 32 K and 9.0 K, respectively. The pyroelectric charge measurement shows an anomaly at about 9.0 K, and conrmed the presence of a reversible spontaneous polarization. From the impurity eect of non-magnetic Mg2+ on the magnetic susceptibility and the dielectric constant, the Neel temperature was found to be reduced in accordance with a lowering of the ferroelectric phase transition point. Moreover, the broad peak around 32 K of the pure sample splits into two sharp peaks through the impurity doping.
Are the effects of blood pressure lowering treatment diminishing?: meta-regression analyses
Yoichi Sekizawa,Yoko Konishi,Moriyo Kimura 대한고혈압학회 2019 Clinical Hypertension Vol.25 No.1
Background: Previous studies have suggested that the effects of medical interventions tend to diminish over time. We investigated whether the effects of blood pressure lowering treatment on all-cause mortality and stroke have diminished over time. Methods: We conducted meta-regression analyses. We extracted the target trials from two recently published comprehensive systematic reviews and meta-analyses. Adopted variables were relative risk (RR) of all-cause mortality and stroke, trial start year, mean age, sample size, baseline systolic blood pressure (SBP), difference in attained SBP reduction between intervention groups and control groups (SBP difference), and regional dummies. We implemented single meta-regressions, in which the dependent variable was the log of RR and the explanatory variable was each of other adopted variables. We also conducted multiple meta-regressions, in which the dependent variable was the log of RR and explanatory variables were all of other adopted variables. Our variable of greatest interest was trial start year. Results: The included reviews assessed 85 trials with a total of 343,126 participants. Although trial start year was positively associated with the log of RR in the results of single meta-regressions, it lost significance in multiple meta-regressions for both allcause mortality and stroke. Conclusions: The effects of blood pressure lowering treatment on all-cause mortality and stroke have not diminished over time.