SSiCP : a new SVM based Recursive Feature Elimination Algorithm for Multiclass Cancer Classification

Xiaobo Li,Xue Gong,Xiaoning Peng,Sihua Peng 보안공학연구지원센터 2014 International Journal of Multimedia and Ubiquitous Vol.9 No.6

Caenorhabditis elegans as a useful model to assess the effect of spermiogenesis induced by three teratogens

Yunhui Li,Minhui Zhang,Xiaobo Li,Juan Zhang,Ran Liu,Geyu Liang,Yuepu Pu,Lihong Yin 대한독성 유전단백체 학회 2015 Molecular & cellular toxicology Vol.11 No.2

Caenorhabditis elegans (C. elegans), with homologous genes and conservative spermiogenesis in mammals, has a series of advantages to illuminate and study many biological processes including reproductive toxicity. So it is a very useful model to assess environmental and ecological toxicity. Here we introduce C. elegans as an animal model and three known mammalian sperm teratogens methyl methanesulfonate, mitomycin C and cyclophosphamide as experimental materials to elucidate the efficient and reliability for the assessment of chemicals altering spermiogenesis. The results showed that, with the aid of the brood size, spermatids activation, trans-activation, sperm competition as the endpoints, the adverse effects of three teratogens on C. elegans were detected. Thus, while the data of chemicals induced spermiogenesis abnormality is incomplete, we speculated that C. elegans could be a useful animal model to explore the effects on spermiogenesis of chemicals. And we propose an increased application of C. elegans that complements other model system in the reproductive toxicity.

Global Finite-time Stabilization for a Class of High-order Nonlinear Systems with Multiple Unknown Control Directions

Jing Li,Jian Wu,Xiguo Yuan,Xiaobo Li,Liefu Ai 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.1

This paper considers the problem of the global finite-time stabilization for the high-order nonlinear systemswith unknown control directions. Due to the uncertainty of control directions, the paper analyzes all possibleconditions of the directions. The Lyapunov-based logic switching rule ensures that we can find the correct controldirections. The adaptive switching controller with a switching parameter which is to be tuned online guarantees thatthe derivative of Lyapunov function is less than a negative definite function and the closed-loop system is globallyfinite-time stable. The effectiveness of the proposed method is illustrated by an example.

Nonlinear Wave and Currents Loads Analysis of Offshore Wind Turbines

Xiaobo Chen,Jing Li,Jianyun Chen 대한토목학회 2014 KSCE JOURNAL OF CIVIL ENGINEERING Vol.18 No.6

In recent years, the offshore wind energy has increased in popularity due to the demand for renewable energy. Being built in a verydynamic environment, the nonlinear wave and current loads on offshore wind turbines are required to be investigated for design. Thewave and current kinematics were calculated by the model that the wave propagates on a linear shear current which was developedby Dalrymple based on the stream function wave theory. The wave and current loads were calculated based on the Morison equation. For the engineering application purpose, some problems such that the wave and current kinematics models, the wave and currentcombination schemes in statistics, and the free surface’s influences on wave and current loads were discussed. At the end, thenonlinear results were compared with linear results to verify the calculation correctness.

Correlation between red blood cell distribution width/platelet count and prognosis of newly diagnosed diffuse large B-cell lymphoma

Xiaobo Liu,Yanliang Bai,Ying Liu,Weiya Li,Yabin Cui,Jinhui Xu,Xingjun Xiao,Xiaona Niu,Kai Sun 대한혈액학회 2023 Blood Research Vol.58 No.4

Background Red blood cell distribution width/platelet count ratio (RPR) is a reliable prognostic assessment indicator for numerous diseases. However, no studies to date have examined the relationship between RPR and the prognosis of diffuse large B-cell lymphoma (DLBCL). Therefore, this study aimed to investigate the correlation between RPR and the clinical characteristics and prognosis of patients with diffuse large B-cell lymphoma. Methods We retrospectively studied 143 patients with newly diagnosed DLBCL and used the median value as the RPR threshold. We also investigated the correlation of pretreatment RPR level with clinical characteristics and its impact on DLBCL prognosis. Results Using the median value as the cut-off, patients with DLBCL were divided into a low RPR group (<0.0549) and a high RPR group (≥0.0549). Patients in the high RPR group were older, had a later Ann Arbor stage, were prone to bone marrow invasion, and had a higher National Comprehensive Cancer Network International Prognostic Index score (P < 0.05). A survival analysis showed that progression-free survival (PFS) (P =0.003) and overall survival (OS) (P <0.0001) were significantly shorter in the high versus low RPR group. A multifactorial Cox analysis showed that bone marrow invasion and elevated lactate dehydrogenase (LDH) were separate risk factors for PFS (P <0.05), while an RPR ≥0.0549 and elevated LDH were separate risk factors for OS (P <0.05). Conclusion A high RPR (≥0.0549) in patients with newly diagnosed DLBCL is an independent risk factor for a poor prognosis.

Luminescence Properties of Si4+-doped LiZnPO4:Eu3+ and Application in the Development of Latent Fingermarks

Xiaobo Xiong,Jiangchun Li 한국전기전자재료학회 2021 Transactions on Electrical and Electronic Material Vol.22 No.1

Si 4+ and Eu 3+ co-doped LiZnPO 4 phosphors (LZPS:Eu 3+ ) with red luminescence were prepared by high temperature solidstate reaction. The maximum photoluminescence intensity is achieved at the Eu 3+ content of 12% (molar concentration). The study also investigated the effect on luminescent properties of LiZnPO 4 :Eu 3+ by the introduction of Si 4+ into the host to substitute P 5+ . The Eu 3+ emission intensity at 592 nm and 612 nm is enhanced by 105% and 108%, respectively. Decreasing the amount of Eu 3+ signifi cantly reduces the raw material costs. The phosphor is efficiently excited under 395 nm and 254 nm ultraviolet radiation, and is used as the red component in white light-emitting diodes (WLEDs) or fluorescent lamps. The excitation spectra consist of a broad band extending 200–280 nm and a series of sharp peaks extending 310–500 nm, centered at 395 nm, which corresponds to the charge transfer band of O 2− → Eu 3+ and the f → f transition of Eu 3+ , respectively. The study applies this distinctly bright phosphor in the detection and imaging of lipid fingermarks on common non-porous and semi-porous substrates such as colored paper, glass, porcelain, and leather, etc. All results indicate that the LZPS:Eu 3+ phosphor is an ideal detection powder for background interference reduction due to its high fluorescence brightness which offers high contrast images, which is applicable to the development of fi ngermarks on the common non-porous and semiporous substrates.

Towards an Innovation-driven Nation

Xiaobo Wu,Jing Li 과학기술정책연구원 2015 STI Policy Review Vol.6 No.1

The rise of latecomer countries across the world directs academic attention to their catching-up and innovation processof seizing technological opportunities and combining internal and external knowledge. Different from the developed economies as well as the newly industrialized economies, China presents a special innovation environment, wherein its technology regime, market opportunities, and institutions are complex and the globalization trend affects competition in a broader way. In thiscontext, we clarify and extend the framework of “secondary innovation”. This framework describes the dynamics of those with relatively poor resources and capabilities in their efforts to capture the values of mature/emerging technology or business models by acquiringthem from across borders and then adapting to catching-up contexts. Such processes, differentiated from original innovation that involves the whole process from R&D to commercialization, has become a prevailing regime during paradigm shifts. In particular, unlike the traditional catch-up literature that focuses more on technology, the secondary innovation framework inclusively contains both technology and business model innovation, and puts forward the co-evolution between the two elements, which is more applicable to China’s context. In accordance, we also provide implications towards fulfilling the goal of building an innovation-driven nation.

Preparation of high surface area carborundum-supported cobalt catalysts for hydrogen production by ammonia decomposition

Li Guoru,Tan Yuhang,Lei Zhiping,Yin Fengxiang,He Xiaobo 한국탄소학회 2023 Carbon Letters Vol.33 No.3

Ammonia is a potential fuel for producing and storing hydrogen, but its usage is constrained by the high cost of the noble metal catalysts to decompose NH3. Utilizing non-precious catalysts to decompose ammonia increases its potential for hydrogen production. In this study, carborundum (SiC)-supported cobalt catalysts were prepared by impregnating Co3O4 nanoparticles (NPs) on SiC support. The catalysts were characterized by high-resolution transmission electron microscope, X-ray photoelectron spectroscopy, temperature programmed reduction, etc. The results show that the large specific surface area of SiC can introduce highly distributed Co3O4 NPs onto the surface. The amount of Co in the catalysts has a significant effect on the catalyst structure, particle size and catalytic performances. Due to the interaction of cobalt species with SiC, the 25Co/SiC catalyst provided the optimal ammonia conversion of 73.2% with a space velocity of 30,000 mL gcat−1 h−1 at 550 °C, corresponding to the hydrogen production rate of 24.6 mmol H2 gcat−1 min−1. This research presents an opportunity to develop highly active and cost-effective catalysts for hydrogen production via NH3 decomposition.

Melting Cell Based Compensated Design Method for Improving Dimensional Accuracy of Additively Manufactured Thin Channels

Li Sun,Xiaobo Ren,Jianying He,Zhiliang Zhang 한국정밀공학회 2022 International Journal of Precision Engineering and Vol.9 No.2

Powder-bed fusion additive manufacturing technology makes it possible to produce parts with complicated geometry and high accuracy. However, dimensional deviation caused by powder overmelting and dross formation is still a challenge for manufacturing thin channels. In this study, the origins of the overmelting of printed thin channels were analyzed and a concept called “melting cell” is proposed to describe and quantify the geometric error. Based on the geometrical relationship between the melting cell and target channel, a method for predicting and optimizing the final geometry of thin channels is outlined. In order to verify the method, geometries of thin horizontal circular channels in various sizes are studied as examples. The predicted results by the proposed method show a remarkable agreement with available experimental results. Moreover, a new egg-shaped compensated design, which is able to improve the dimensional accuracy of thin horizontal circular channels, is presented. The proposed method is simple yet very effective. It can be easily extended to the manufacturing of thin channels with various shapes, materials, and different powder bed fusion processes.

Decreasing Global Greenhouse Effects by Biochar Amendment in a Double Rice Field of South China

Xiaobo Qin,Yue Li,Yunfan Wan 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6