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- 저자 : Wen-Tao Ma (검색결과 20 건)
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Energy analysis of the deformation and failure process of sandstone and damage constitutive model
Tao Wen,Huiming Tang,Junwei Ma,Junwei Ma 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.2
The damage theory was introduced to clarify and simulate the strain softening property of rocks. On the basis of the theory, an energy method was utilized to portray the rock mechanical properties from microscopic perspective. Firstly, from the perspective of rock microstructure, damage variable (expressed as D) was redefined by dividing the rock into three portions: undamaged materials, damaged materials and micro-defects, and an impact factor was introduced as the connection between the damaged material and the micro-defects. Meanwhile, the method for determining the impact factor was presented. Secondly, the damage variable was redefined in light of energy dissipation, then damage evolution analysis was conducted based on triaxial tests. An improved rock damage constitutive model was further obtained in another expression to reflect the energy change law. Subsequently, the relationship between D and the deformation and failure process of rocks was analyzed on account of the damage evolution equation formularized by fitting to a logistic function, which can measure the influence of energy dissipation on the propagation of micro-defects. By comparing between experimental results and theoretical results of illustrative examples, the effectiveness of the improved model was validated, and the its application was also discussed.
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Supragingival Plaque Microbial Community Analysis of Children with Halitosis<sup>s</sup>
( Wen Ren ),( Qun Zhang ),( Xuenan Liu ),( Shuguo Zheng ),( Lili Ma ),( Feng Chen ),( Tao Xu ),( Baohua Xu ) 한국미생물 · 생명공학회 2016 Journal of microbiology and biotechnology Vol.26 No.12
As one of the most complex human-associated microbial habitats, the oral cavity harbors hundreds of bacteria. Halitosis is a prevalent oral condition that is typically caused by bacteria. The aim of this study was to analyze the microbial communities and predict functional profiles in supragingival plaque from healthy individuals and those with halitosis. Ten preschool children were enrolled in this study; five with halitosis and five without. Supragingival plaque was isolated from each participant and 16S rRNA gene pyrosequencing was used to identify the microbes present. Samples were primarily composed of Actinobacteria, Bacteroidetes, Proteobacteria, Firmicutes, Fusobacteria, and Candidate phylum TM7. The α and β diversity indices did not differ between healthy and halitosis subjects. Fifteen operational taxonomic units (OTUs) were identified with significantly different relative abundances between healthy and halitosis plaques, and included the phylotypes of Prevotella sp., Leptotrichia sp., Actinomyces sp., Porphyromonas sp., Selenomonas sp., Selenomonas noxia, and Capnocytophaga ochracea. We suggest that these OTUs are candidate halitosis-associated pathogens. Functional profiles were predicted using PICRUSt, and nine level-3 KEGG Orthology groups were significantly different. Hub modules of co-occurrence networks implied that microbes in halitosis dental plaque were more highly conserved than microbes of healthy individuals` plaque. Collectively, our data provide a background for the oral microbiota associated with halitosis from supragingival plaque, and help explain the etiology of halitosis.
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Ma, Tao,Deng, Kai-Dong,Tu, Yan,Jiang, Cheng-Gang,Zhang, Nai-Feng,Li, Yan-Ling,Si, Bing-Wen,Lou, Can,Diao, Qi-Yu Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.2
This study aimed to investigate dietary concentrate:forage ratios (C:F) and undegraded dietary protein (UDP) on nitrogen balance and urinary excretion of purine derivatives (PD) in lambs. Four Dorper${\times}$thin-tailed Han crossbred castrated lambs with $62.3{\pm}1.9$ kg body weight at 10 months of age were randomly assigned to four dietary treatments in a $2{\times}2$ factorial arrangement of two levels of C:F (40:60 and 60:40) and two levels of UDP (35% and 50% of CP), according to a complete $4{\times}4$ Latin-square design. Each experimental period lasted for 19 d. After a 7-d adaptation period, lambs were moved into individual metabolism crates for 12 d including 7 d of adaption and 5 d of metabolism trial. During the metabolism trial, total urine was collected for 24 h and spot urine samples were also collected at different times. Urinary PD was measured using a colorimetric method and creatinine was measured using an automated analyzer. Intake of dry matter (DM) (p<0.01) and organic matter (OM) (p<0.01) increased as the level of UDP decreased. Fecal N was not affected by dietary treatment (p>0.05) while urinary N increased as the level of UDP decreased (p<0.05), but decreased as dietary C:F increased (p<0.05). Nitrogen retention increased as dietary C:F increased (p<0.05). As dietary C:F increased, urinary excretion of PD increased (p<0.05), but was not affected by dietary UDP (p>0.05) or interaction between dietary treatments (p>0.05). Daily excretion of creatinine was not affected by dietary treatments (p<0.05), with an average value of $0.334{\times}0.005$ mmol/kg $BW^{0.75}$. A linear correlation was found between total PD excretion and PDC index ($R^2$ = 0.93). Concentrations of creatinine and PDC index in spot urine were unaffected by sampling time (p>0.05) and a good correlation was found between the PDC index (average value of three times) of spot urine and daily excretion of PD ($R^2$ = 0.88). These results suggest that for animals fed ad libitum, the PDC index in spot urine is effective to predict daily excretion of PD. In order to improve the accuracy of the spot sampling technique, an appropriate lag phase between the time of feeding and sampling should be determined so that the sampling time can coincide with the peak concentration of PD in the urine.
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Tao Jin,Yuying Lin,Shichou Han,Guangchang Ma,Haibo Wen,Zhengqiang Peng 한국응용곤충학회 2019 Journal of Asia-Pacific Entomology Vol.22 No.3
Five candidate species for biocontrol of Opisina arenosella Walker, a destructive pest of palm trees, were evaluated. To compare host performance, 5 Trichogramma species were allowed to parasitize O. arenosella eggs of different ages and egg densities. The parasitization capacity of two species, T. embryophagum and T. japonicum, were evaluated with respect to adult age. Treatments consisted of field with releases of T. embryophagum or T. japonicum set up in Danzhou, Hainan, and the pest densities was recorded periodically. The results showed that T. embryophagum, T. chilonis, and T. dendrolimi had a strong parasitic ability on 0-day-old O. arenosella eggs. In species comparisons, the parasitism rates of T. embryophagum on 1-day-old and 4-day-old eggs, and T. japonicum on 2-day-old, 3-day-old, and 5-day-old eggs of O. arenosella were significantly higher than those of other Trichogramma species. At densities of 40 and 35 eggs/tube (84.8 cm 3 ), the numbers of eggs parasitized by T. embryophagum and T. japonicum were the highest, at 29.9 and 24.6, respectively. During the first 24-h, the numbers of eggs parasitized by T. embryophagum and T. japonicum were 110.6 and 82.2, accounting for 84.7% and 59.5%, respectively, of the total parasitized eggs. After 2 months releases, the larvae and pupa density of O. arenosella under T. embryophagum and T. japonicun treatment were 0.95 and 0.94 individuals/leaflet, respectively, were significantly lower than untreated control (1.6 individuals/leaflet). These findings encouraged that T. embryophagum and T. japonicun are able to be used for biological control for O. arenosella.
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Exploring the oral microflora of preschool children
Wen Ren,Qun Zhang,Xuenan Liu,Shuguo Zheng,Lili Ma,Feng Chen,Tao Xu,Baohua Xu 한국미생물학회 2017 The journal of microbiology Vol.55 No.7
The oral cavity is one of the most important and complicated habitats in our body and supports diverse microbial communities. In this study, we aimed to determine the bacterial diversity and composition of various oral micro-niches. Samples were collected from supragingival plaque, saliva, and tongue coating from 10 preschool children (30 samples total). 16S rRNA gene pyrosequencing dataset generated 314,639 clean reads with an average of 10,488 ± 2,787 reads per sample. The phyla Firmicutes, Proteobacteria, Actinobacteria, Bacteroidetes, and Fusobacteria were predominant, accounting for more than 90% of the total sequences. We found the highest α diversity, microbial richness, and evenness in plaque, compared with saliva and tongue coating. Plaque was also distinguished from saliva and tongue coating by phylogenetic distances (weighted UniFrac). Taxa with different relative abundances were further identified, confirming the existence of microbial differences across the three niches. Core microbiomes were defined of each niche; however, only a small proportion of operational taxonomic units (8.07%) were shared by the three niches. Coaggregation between Actinomyces spp. and Streptococcus spp. and other correlations among periodontal pathogens, such as Prevotella, Fusobacteria, Capnocytophaga, and Tannerella, were shown by a co-occurrence network. In summary, our study provides a framework of oral microbial communities in the population of preschool children as a baseline for further studies of oral diseases related to microbes.
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Wen-Tao Yi,Chun-Yan Yan,Pei-Hua Ma 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.3
Investigations were conducted to purify crude Li_2CO_3 via direct carbonation with CO_2-water solutions at atmospheric pressure. The experiments were carried out in a slurry bubble column reactor with 0.05 m inner diameter and 1.0 m height. Parameters that may affect the dissolution of Li_2CO-3 in the CO_2-water solutions such as CO-2-bubble perforation diameter, CO_2 partial pressure, CO_2 gas flow rate, Li-2CO-3 particle size, solid concentration in the slurry,reaction temperature, slurry height in the column and so on were investigated. It was found that the increases of CO_2partial pressure, and CO_2 flow rate were favorable to the dissolution of Li_2CO_3, which had the opposite effects with Li_2CO_3 particle size, solid concentration, slurry height in the column and temperature. On the other hand, in order to get insight into the mechanism of the refining process, reaction kinetics was studied. The results showed that the kinetics of the carbonation process can be properly represented by 1−3(1−X)^(2/3)+2(1−X)=kt+b, and the rate-determining step of this process under the conditions studied was product layer diffusion. Finally, the apparent activation energy of the carbonation reaction was obtained by calculation. This study will provide theoretical basis for the reactor design and the optimization of the process operation.
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Wang, Wen-Tao,Li, Yin,Ma, Jie,Chen, Xiao-Bing,Qin, Jian-Jun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.9
Background: Epidermal growth factor receptor (EGFR) mutations and echinoderm microtubule associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) define specific molecular subsets of lung adenocarcinomas with distinct clinical features. Our purpose was to analyze clinical features and prognostic value of EGFR gene mutations and the EML4-ALK fusion gene in lung adenocarcinoma. Patients and Methods: EGFR gene mutations and the EML4-ALK fusion gene were detected in 92 lung adenocarcinoma patients in China. Tumor marker levels before first treatment were measured by electrochemiluminescence immunoassay. Results: EGFR mutations were found in 40.2% (37/92) of lung adenocarcinoma patients, being identified at high frequencies in never-smokers (48.3% vs. 26.5% in smokers; P=0.040) and in patients with abnormal serum carcinoembryonic antigen (CEA) levels before the initial treatment (58.3% vs. 28.6%, P=0.004). Multivariate analysis revealed that a higher serum CEA level before the initial treatment was independently associated with EGFR gene mutations (95%CI: 1.476~11.343, P=0.007). We also identified 8 patients who harbored the EML4-ALK fusion gene (8.7%, 8/92). In concordance with previous reports, younger age was a clinical feature for these (P=0.008). Seven of the positive cases were never smokers, and no coexistence with EGFR mutation was discovered. In addition, the frequency of the EML4-ALK fusion gene among patients with a serum CEA concentration below 5ng/ml seemed to be higher than patients with a concentration over 5ng/ml (P=0.021). No significant difference was observed for time to progression and overall survival between EML4-ALK-positive group and EML4-ALK-negative group or between patients with and without an EGFR mutation. Conclusions: The serum CEA level before the initial treatment may be helpful in screening population for EGFR mutations or EML4-ALK fusion gene presence in lung adenocarcinoma patients.
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THE RELATION BETWEEN SANDSTORMS AND STRONG WINDS IN XINJIANG, CHINA
WANG, XU,MA, YU,CHEN, HONGWU,WEN, GANG,CHEN, SHOUJUN,TAO, ZUYU,CHUNG, YONG-SEUNG 한국교원대학교 환경과학연구소 2004 환경연구논문집 Vol.- No.8
With observational data spanning 1961-1999 from 90 meteorological stations in Xinjiang, China, the spatial and temporal characteristics of sandstorms and strong winds, and the contribution of strong winds to the occurrence of sandstorms are analyzed. Moreover, the dominant wind direction and minimum wind speeds during sandstorm periods are discussed. The research shows chat although possessing similar climatic trends, sandstorms and strong winds in Xinjiang have opposite geographical distributions, i.e. places with more sandstorms show fewer strong winds. The contribution of strong winds to sandstorms in northern Xinjiang is larger than that in southern Xinjiang. The dominant wind directions clerarly indicate the paths of the weather systems that introduced the sandstorms. The minimum wind speeds in the sandstoims were ova 10 ms^(-1) in northern and eastern Xinjiang and in the Turpan and Yanqi Basins of southern Xinjiang. In Tarim Basin of southern Xinjiang, however, the minimum wind speed was about 6-8 ms^(-1), and even 6 ms^(-1) at its southero edge.
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