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      • KCI등재

        산업연관 분석에 의한 미디어 산업의 경제적 효과 분석

        고준희(Gao, Jun Xi),여위(Yu, Wei),이혁진(Lee, Hyeok Jin) 한국문화산업학회 2020 문화산업연구 Vol.20 No.1

        본 연구는 확장된 미디어에 대한 정의를 정리하고 미디어산업의 범위를 정의한 후 미디어산업의 경제적 효과를 분석하는데 목적이 있다. 이를 위해 본 연구는 한국은행에서 발표한 산업연관분석표를 활용하여 미디어산업의 생산유발계수, 부가가치유발계수, 영향력계수, 감응도계수를 분석하고 경제적 파급효과를 알아보았다. 분석결과 미디어산업의 생산유발계수 열 합계는 2010년 2.8983에서 2014년 2.5014로, 행 합계는 2010년 3.1755에서 2014년 2.7347로 감소하였다. 감응도계수는 2010년 1.1603에서 2014년 1.1826으로, 영향력계수는 2010년 1.0590에서 2014년 1.0817로 다소 증가하였다. 부가가치유발계수는 2010년 0.9451, 2014년 0.8471로 나타났다. 미디어산업은 다른 산업의 중간재로 사용이 늘어나고 있고 다른 산업을 견인하는 영향력도 증가하고 있었으며 기술 중심으로 변화하고 있지만 아직은 노동집약적 산업으로 높은 고용창출을 만들어 냄을 알 수 있었다. 또한 올드미디어기반산업은 다른 산업의 생산과 수요 변화에 미치는 영향력이 매우 크고 뉴미디어산업은 여러 분야에서 활용빈도가 높아짐을 알 수 있었다. This study summarized the definition of extended media and defined the scope of the media industry, and then studied the economic effects of the media industry. For this purpose, the analysis of production induction coefficient, value-added induction coefficient, influence coefficient, and sensitivity coefficient of the media industry was carried out using the industrial correlation analysis table, and the economic ripple effect was examined. The analysis shows that the media industry is increasing its use as an intermediate material of other industries, and the influence of driving other industries is increasing, and it is changing to technology, but it is still creating a high job creation by labor-intensive industry. In addition, the oldmedia-based industry has a great influence on the production and demand changes of other industries, and the newmedia industry has a high frequency of utilization in various fields.

      • Segmentation of Handwritten Character

        Min, Gao,Lin, Chen Xi,Jing, Zhang,Wei, Luo 대한전자공학회 1992 HICEC:Harbin International Conference on Electroni Vol.1 No.1

        Recognition of handwritten character is an active field which has not been solved yet. In the paper, we discuss the segmentation of handwritten character. An algorithm of connected character segmentation based on the orientation of main axis of reference character and an algorithm of broken character segmentation based on the distance between the centres of two parts are put forward. These algorithm are used in an automatic table input system and has been got a good result.

      • Expression of Pituitary Tumor Transforming Gene 1 is an Independent Factor of Poor Prognosis in Localized or Locally Advanced Prostate Cancer Cases Receiving Hormone Therapy

        Cao, Xi-Liang,Gao, Jiang-Ping,Wang, Wei,Xu, Yong,Shi, Huai-Yin,Zhang, Xu Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.7

        We investigated the prognostic value of pituitary tumor transforming gene 1 (PTTG1) expression according to clinicopathological features among localized or locally advanced prostate cancer cases receiving hormone therapy. A retrospective study involved 64 patients receiving combined androgen blockade treatment was performed. PTTG1 expression was determined by immunohistochemical staining using initial needle biopsy specimens for diagnosis. Associations of PTTG1 with various clinicopathological features and disease-free survival were examined via uni- and multivariate analyses. No association between PTTG1 expression and clinical T stage, Gleason score, pretreatment PSA levels, risk groups was found (p =0.682, 0.184, 0.487, 0.571, respectively). Univariate analysis revealed that increased PTTG1 expression, T3 stage and high risk group were associated with increased risk of disease progression (p =0.000, 0.042, and 0.001), and high PSA level had a tendency to predict disease progression (p =0.056). Cox hazard ratio analysis showed that PTTG1 low expression (p =0.002), PTTG1 high expression (p =0.000) and high risk group (p =0.0147) were significantly related to decreased disease-free survival. In conclusion, PTTG1 expression determined by immunohistochemical staining in needle biopsy specimens for diagnosis is a negative prognostic factor for progression in localized or locally advanced prostate cancer receiving hormone therapy.

      • KCI등재

        Four-Hour Fasting for Semifluids and 2-Hour Fasting for Water Improves the Patient Experience of Esophagogastroduodenoscopy: A Randomized Controlled Trial

        Cai Meng-Xi,Gao Ye,Li Li,Feng Wen,Wang Yi-Lin,Li Zhao-Shen,Xin Lei,Wang Luo-Wei 거트앤리버 소화기연관학회협의회 2023 Gut and Liver Vol.17 No.3

        Background/Aims: We aimed to investigate the comfort, safety, and endoscopic visibility during esophagogastroduodenoscopy (EGD) afforded by a modified 4-hour semifluid and 2-hour water (“4+2”) fasting protocol. Methods: In this parallel group, endoscopist-blinded, randomized controlled trial, outpatients undergoing unsedated diagnostic EGD from 10:30 AM to 12:00 PM were randomly assigned to either a “4+2” protocol group or a conventional fasting group. The participants’ comfort during the fasting period and procedure was measured using the visual analog scale, and mucosal visibility was measured by endoscopists using the total visibility score. Satisfaction was defined as a visual analog scale score of ≤3. The primary outcome was the participants’ comfort during fasting. Results: One hundred and six and 108 participants were randomized to the “4+2” protocol and control groups, respectively. Participants’ comfort before EGD was significantly higher in the “4+2” protocol group measured by both the proportion of satisfaction (86.8% vs 63.9%, p=0.002) and the visual analog scale score (median [interquartile range]: 1.0 [1.0–2.0] vs 3.0 [1.0–4.0], p<0.001). The proportion of satisfaction during EGD also significantly improved (59.4% vs 45.4%, p=0.039) in the “4+2” protocol group. The total visibility score was unaffected by the fasting protocol (5.0 [4.0–5.0] vs 4.0 [4.0–5.0], p=0.266). No adverse events were observed during the study. Conclusions: The “4+2” protocol was more comfortable and provided equal mucosal visibility and safety compared with conventional fasting for unsedated EGD. (

      • A Computational Investigation of Fuel-Air Mixture Formation in the TR Combustion System

        ( He Xu ),( Xi Yan Gao ),( Wei Guo Liu ),( Chun Ming Liao ),( De Sheng Yang ) 한국액체미립화학회 2005 한국액체미립화학회 학술강연회 논문집 Vol.2005 No.-

        A new combustion system applied in the 135-type diesel engine - TR(Three-Rapidity), was modified from deep cave ω combustion chamber with an oriented arc in the middle of chamber wall, and perfectly fit in a nozzle with orifices in conic section plus orifice in the center. In this paper, three-dimensional numerical simulation was completed and compared on TR combustion system and original 135 diesel engine combustion system. The results show that in TR combustion system, fuel ignition location is near TDC, and premix combustion proportion increases. The oriented arc, contracted cave and centric spray contribute to enhancing air flow, making more reasonable fuel distribution and formatting more homogeneous mixture. The usage of air in chamber is effectively increased and heat loss from the chamber wall is obviously decreased. The cold start performance of the engine is improved also. A performance test on TR combustion system was made on a 135-type diesel engine. The results demonstrate that TR has better exhaust smoke than original engine. At the low and part load, NOX emission of TR combustion system is less than original diesel, but more at high load conditions, which could be solved by delaying fuel spray timing. TR combustion has much potential to improve emission with less structure changed of original engine, so it has large foreground.

      • KCI등재

        Experimental study on CO2 bubble dynamics under different solution viscosity and absorbent concentration

        Yang Jia-xi,Gao Dan,Qi You-wei,Zhang Heng 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.8

        Carbon dioxide (CO2) emitted by fossil energy combustion is related to the greenhouse effect. To furtherstudy the motion dynamics of CO2 bubbles in various solutions so as to better absorb them, a CO2 bubble experimentalplatform was built. The growth and motion of a single CO2 bubble were experimented in five concentrations ofNaOH, NaHCO3 solutions and five viscosity deionized waters, photographed with a high-speed camera and importedinto PyCharm for analysis. Based on this, four kinds of CO2 bubbles were experimentally studied. The results show thatthe viscosity leads to the increase of rising time; the maximum rise time is 0.518 s when the viscosity is 100 mPa·s, theaspect ratio  of CO2 bubble in solution, there will be an “L” distribution, and the minimum rise time is close to risingafter the bubble is separated from the injector. NaHCO3 inhibits the reaction between NaOH solution and CO2, resultingin the cross-section ratio  change decreasing. The concentration of NaOH solution most conducive to CO2absorption is 0.039 g/ml and 0.058 g/ml.

      • KCI등재

        Prolyl endopeptidase remodels macrophage function as a novel transcriptional coregulator and inhibits fibrosis

        Lin Shuang-Zhe,Wu Wei-Jie,Cheng Yu-Qing,Zhang Jian-Bin,Jiang Dai-Xi,Ren Tian-Yi,Ding Wen-Jin,Liu Mingxi,Chen Yuan-Wen,Fan Jian-Gao 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

        Macrophages are immune cells crucial for host defense and homeostasis maintenance, and their dysregulation is involved in multiple pathological conditions, such as liver fibrosis. The transcriptional regulation in macrophage is indispensable for fine-tuning of macrophage functions, but the details have not been fully elucidated. Prolyl endopeptidase (PREP) is a dipeptidyl peptidase with both proteolytic and non-proteolytic functions. In this study, we found that Prep knockout significantly contributed to transcriptomic alterations in quiescent and M1/M2-polarized bone marrow-derived macrophages (BMDMs), as well as aggravated fibrosis in an experimental nonalcoholic steatohepatitis (NASH) model. Mechanistically, PREP predominantly localized to the macrophage nuclei and functioned as a transcriptional coregulator. Using CUT&Tag and co-immunoprecipitation, we found that PREP was mainly distributed in active cis-regulatory genomic regions and physically interacted with the transcription factor PU.1. Among PREP-regulated downstream genes, genes encoding profibrotic cathepsin B and D were overexpressed in BMDMs and fibrotic liver tissue. Our results indicate that PREP in macrophages functions as a transcriptional coregulator that finely tunes macrophage functions, and plays a protective role against liver fibrosis pathogenesis.

      • SCIESCOPUSKCI등재

        Taxonomy of fungal complex causing red-skin root of Panax ginseng in China

        Lu, Xiao H.,Zhang, Xi M.,Jiao, Xiao L.,Hao, Jianjun J.,Zhang, Xue S.,Luo, Yi,Gao, Wei W. The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.3

        Background: Red-skin root of Asian ginseng (Panax ginseng) significantly reduces the quality and limits the production of ginseng in China. The disease has long been thought to be a noninfectious physiological disease, except one report that proved it was an infectious disease. However, the causal agents have not been successfully determined. In the present study, we were to reveal the pathogens that cause red-skin disease. Methods: Ginseng roots with red-skin root symptoms were collected from commercial fields in Northeast China. Fungi were isolated from the lesion and identified based on morphological characters along with multilocus sequence analyses on internal transcription spacer, β-tubulin (tub2), histone H3 (his3), and translation elongation factor 1α (tef-1α). Pathogens were confirmed by inoculating the isolates in ginseng roots. Results: A total of 230 isolates were obtained from 209 disease samples. These isolates were classified into 12 species, including Dactylonectria sp., D. hordeicola, Fusarium acuminatum, F. avenaceum, F. solani, F. torulosum, Ilyonectria mors-panacis, I. robusta, Rhexocercosporidium panacis, and three novel species I. changbaiensis, I. communis, and I. qitaiheensis. Among them, I. communis, I. robusta, and F. solani had the highest isolation frequencies, being 36.1%, 20.9%, and 23.9%, respectively. All these species isolated were pathogenic to ginseng roots and caused red-skin root disease under appropriate condition. Conclusion: Fungal complex is the causal agent of red-skin root in P. ginseng.

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