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Monitoring of 75 veterinary drug residues for fishery products on the Korean market with LC-MS/MS
Eunhye Lee,Sooyeon Choi,Seonhye Jo,Younggi Jung,Hyunjeong You,Joonshik Park,Mikyoung Jin,Sookhee Ha,Jaeyoung Shim,Kwangsoo Yoo,Gyeongyeol Kim,Kwangsoo Lee,Dongsul Kim,Changhee Lee 한국분석과학회 2017 학술대회논문집 Vol.2017 No.11
윤은혜(Eunhye Youn),심영보(Youngbo Aram Shim),김선범(Sunbum Kim),이기혁(Geehyuk Lee) 한국HCI학회 2021 한국HCI학회 학술대회 Vol.2021 No.1
스마트 글라스를 착용하고 양손을 사용하여 과업을 수행하고 있을 때, 머리 운동은 입력 신호로 사용할 수 있는 좋은 선택지 중에 하나다. 본 연구에서는 handsfree하고 낮은 수준의 시각적 주목으로 수행 가능한 머리 운동 기반 스마트 글라스의 2 단계 계층 메뉴 선택기법을 디자인하였다. 머리의 회전 운동의 적절한 가동범위 및 적절한 타겟 크기를 탐색한 결과, 수평 방향(yaw)범위는 56 도 이내, 수평 방향 타겟의 크기는 12 도 이상이 되어야 함을 확인하였으며, 더불어 2 차 선택 시 타겟까지의 수직 방향 (pitch)거리는 20 도 이내로, 타겟의 크기는 8 도 이상이 되어야 신체 부담을 줄일 수 있음을 확인하였다. 위 결과를 바탕으로 메뉴 선택 기법을 디자인하고, 사용자 스터디를 통하여 시각적 주의 집중이 필요한 다른 주업을 수행하면서 간헐적으로 메뉴 선택을 할 때의 인터랙션 성능을 측정하였다. 그 결과, 숙련된 사용자들은 시각 피드백 없이도 음향 피드백 에만 의지하여 5 x 5 격자 형태의 입력 공간에서 4 가지 타겟의 선택을 74.48%의 정확도로 4620.98㎳ 의 응답 시간으로 수행할 수 있었다.
Three year experiences of 627 robotic single-site surgery cases in single institute: first reports
( Hae Kyung Yoo ),( Eunhye Cho ),( Soo Jung Kim ),( Ahyoung Cho ),( Ji Eun Shim ),( Sa Ra Lee ),( Kyungah Jeong ),( Hye-sung Moon ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-
Objective: The purpose of this study was to report 627 cases of successful robotic single-site (RSS) surgeries and to evaluate the feasibility and safety of RSS surgery in gynecology field. Methods: A total of 627 cases of RSS surgery performed by 3 gynecologic surgeons at Ewha Womans University Medical Center from Nov 2014 to Dec 2017, were collected retrospectively. We reviewed the patients charts and analyzed clinical characteristics and surgical variables. We also analyzed the trends of operation-related variables with one-way ANOVA, Kruskal-Wallis analysis, and linear regression analysis, trend analysis using SPSS version 18.0. Results: All of total 627 cases of robotic single-site surgeries, RSS myomectomy was 221 cases, RSS-hysterectomy was 180 cases, RSS adnexectomy was 190cases, RSS sacrocolpopexy was 26 cases and other RSS surgeries including vaginal vault cystectomy and tumorectomy were 10 cases. There were 2 cases of conversion to multi-site robot surgery, 1 case to laparotomy and 1 case to laparoscopy. The mean age was 39.08±10.05 (16-75) yrs and the main symptoms was routine check-up (389 cases, 62.1%). The mean anesthesia time was 159.67±53.85 (50.0-403.0) mins, mean operation time was 118.19±51.40 (25.0-385.0) mins. The mean docking time was 3.98±2.12(1.1-15) mins, mean EBL was 165.02±197.58 (0-1500) ml, mean hospitalization day was 4.75±1.02(3-14)days. We analyzed 627 cases into 1 yr interval. The mean anesthesia time, operation time, postoperative sips of time were decreased significantly according to the each period. The docking time was decreased significantly after 1yr period. There was a few intraoperative or perioperative complication in 15cases (2.3%). The 8 cases of fever (1.2%), 3 cases of ileus (0.4%), 2 bowel injury case, each one case of AKI and pleural effusion case were noted. Conclusion: RSS surgery is a feasible and safe procedure in variable gynecologic diseases. More experiences to perform RSS surgery can make better surgical results.
어류 분포에 미치는 기후변화 영향 평가를 위한 서식적합성 모형 적용
심태용,배은혜,정진호,Shim, Taeyong,Bae, Eunhye,Jung, Jinho 응용생태공학회 2016 Ecology and resilient infrastructure Vol.3 No.2
Temperature increase and precipitation changes caused by change alter aquatic environments including water quantity and quality that eventually affects the habitat of aquatic organisms. Such changes in habitat lead to changes in habitat suitability of the organisms, which eventually determines species distribution. Therefore, conventional habitat suitability models were investigated to evaluate habitat suitability changes of freshwater fish cause by change. Habitat suitability models can be divided into habitat-hydraulic (PHABSIM, CCHE2D, CASiMiR, RHABSIM, RHYHABSIM, and River2D) and habitat-physiologic (CLIMEX) models. Habitat-hydraulic models use hydraulic variables (velocity, depth, substrate) to assess habitat suitability, but lack the ability to evaluate the effect of water quality, including temperature. On the contrary, CLIMEX evaluates the physiological response against climatic variables, but lacks the ability to interpret the effects of physical habitat (hydraulic variables). A new concept of ecological habitat suitability modeling (EHSM) is proposed to overcome such limitations by combining the habitat-hydraulic model (PHABSIM) and the habitat-physiologic model (CLIMEX), which is able to evaluate the effect of more environmental variables than each conventional model. This model is expected to predict fish habitat suitability according to climate change more accurately. 기후변화에 의한 온도 상승 및 강수량 변화는 수량 및 수질을 포함한 수환경의 변화로 이어져 결과적으로 수생생물의 서식지에 영향을 미친다. 이와 같은 서식지 변화는 생물종의 서식적합도 변화로 이어지고, 서식적합도에 의해 종분포가 결정된다. 따라서 기후변화에 의한 담수 어류의 서식적합성 변화를 예측하기 위하여 기존의 서식적합성 모형을 비교 및 분석하였다. 서식적합성 모형은 PHABSIM, CCHE2D, CASiMiR, RHABSIM, RHYHABSIM, River2D과 같은 서식지-수리 모형과 CLIMEX와 같은 서식지-생리 모형으로 구분하여 조사하였다. 서식지-수리 모형들은 수리학적 인자 (유속, 수심, 기질)를 이용하여 서식적합도를 예측하기 때문에, 수온을 포함한 수질의 영향을 평가할 수 없다. 반면, CLIMEX는 기후 인자에 대한 생물의 생리학적 반응을 평가하기 때문에, 물리적 서식지 (수리학적 인자)의 영향을 평가할 수 없다. 이러한 문제를 해결하기 위하여 서식지-수리 모형인 PHABSIM과 서식지-생리 모형인 CLIMEX의 구동 원리를 융합하여 기존의 모형들보다 다양한 환경 인자에 대한 영향을 예측할 수 있는 새로운 모형인 생태학적 서식적합성 모형 (EHSM)의 개념을 제안하였다. 이 모형은 기후변화에 의한 어류의 서식적합도 변화를 더욱 정확하게 예측할 수 있을 것으로 기대된다.
Aluminum Nanoparticles Induce ERK and p38MAPK Activation in Rat Brain
Jung-Taek Kwon,Gyun-Baek Seo,Eunhye Jo,Mimi Lee,Hyun-Mi Kim,Ilseob Shim,Byung-Woo Lee,Byung-Il Yoon,Pilje Kim,Kyunghee Choi 한국독성학회 2013 Toxicological Research Vol.29 No.3
Aluminum nanoparticles (Al-NPs) are one of the most widely used nanomaterial in cosmetics and medical materials. For this reason, Al-NP exposure is very likely to occur via inhalation in the environment and the workplace. Nevertheless, little is known about the mechanism of Al-NP neurotoxicity via inhalation exposure. In this study, we investigated the effect AL-NPs on the brain. Rats were exposed to Al-NPs by nasal instillation at 1 mg/kg body weight (low exposure group), 20 mg/kg body weight (moderate exposure group), and 40 mg/kg body weight (high exposure group), for a total of 3 times, with a 24-hr interval after each exposure. Inductively coupled plasma mass spectrometry (ICP-MS) analysis indicated that the presence of aluminum was increased in a dose-dependent manner in the olfactory bulb (OFB) and the brain. In microarray analysis, the regulation of mitogen-activated protein kinases (MAPK) activity (GO: 0043405), including Ptprc, P2rx7, Map2k4, Trib3, Trib1, and Fgd4 was significantly over-expressed in the treated mice than in the controls (p = 0.0027). Moreover, Al-NPs induced the activation of ERK1 and p38 MAPK protein expression in the brain, but did not alter the protein expression of JNK, when compared to the control. These data demonstrate that the nasal exposure of Al-NPs can permeate the brain via the olfactory bulb and modulate the gene and protein expression of MAPK and its activity.
Aluminum Nanoparticles Induce ERK and p38MAPK Activation in Rat Brain
Kwon, Jung-Taek,Seo, Gyun-Baek,Jo, Eunhye,Lee, Mimi,Kim, Hyun-Mi,Shim, Ilseob,Lee, Byung-Woo,Yoon, Byung-Il,Kim, Pilje,Choi, Kyunghee Korean Society of ToxicologyKorea Environmental Mu 2013 Toxicological Research Vol.29 No.3
Aluminum nanoparticles (Al-NPs) are one of the most widely used nanomaterial in cosmetics and medical materials. For this reason, Al-NP exposure is very likely to occur via inhalation in the environment and the workplace. Nevertheless, little is known about the mechanism of Al-NP neurotoxicity via inhalation exposure. In this study, we investigated the effect AL-NPs on the brain. Rats were exposed to Al-NPs by nasal instillation at 1 mg/kg body weight (low exposure group), 20 mg/kg body weight (moderate exposure group), and 40 mg/kg body weight (high exposure group), for a total of 3 times, with a 24-hr interval after each exposure. Inductively coupled plasma mass spectrometry (ICP-MS) analysis indicated that the presence of aluminum was increased in a dose-dependent manner in the olfactory bulb (OFB) and the brain. In microarray analysis, the regulation of mitogen-activated protein kinases (MAPK) activity (GO: 0043405), including Ptprc, P2rx7, Map2k4, Trib3, Trib1, and Fgd4 was significantly over-expressed in the treated mice than in the controls (p = 0.0027). Moreover, Al-NPs induced the activation of ERK1 and p38 MAPK protein expression in the brain, but did not alter the protein expression of JNK, when compared to the control. These data demonstrate that the nasal exposure of Al-NPs can permeate the brain via the olfactory bulb and modulate the gene and protein expression of MAPK and its activity.
백종훈 ( Jong-hun Baek ),심홍빈 ( Hongbin Shim ),정강영 ( Kang-young Jung ),이영재 ( Youngjea Lee ),나은혜 ( Eunhye Na ),하돈우 ( Don-woo Ha ) 한국환경기술학회 2021 한국환경기술학회지 Vol.22 No.2
The water quality and flow rate measured every 8 days were evaluated for Yeongsan River basin tributary, the water quality forecasting sites of the Ministry of Environment. In this study, the characteristics of water quality and factors of change according to farming activities of Jiseokcheon4, Manbongcheon, and Hampyeongcheon3, the major tributaries of the Yeongsan River basin, were investigated through load continuity curve and statistical analysis. As a result, it was analyzed that BOD was less affected by the flow rate in the correlation and factor analysis, indicating that there was little inflow of organic matter into the river due to rainfall. It was analyzed that T-P flows into the river during rainfall that affects the flow rate during the farming season, but affects the small-scale rainfall during the non-farming season, which does not significantly affect the flow rate of the river. It is believed that T-P is caused by rainfall from rivers and fresh water from rice paddies caused by farming activities. Accordingly, for water quality management, it is necessary to identify the pollutant sources generated by farming activities and manage the outflow of pollutants by farming period.
과학기술의 일자리 영향 분석에 기반한 좋은 일자리 창출 전략
홍성민(Seongmin Hong),엄미정(Mijung Um),이윤준(Yoonjun Lee),황은혜(Eunhye Hwang),양현채(Hyunchae Yang),박기범(Kibeom Park),송충한(Choonghan Song),이세민(Saymin Lee),심정민(Jungmin Shim),박가람(Garam Park),김종엽(Jongyeob Kim) 과학기술정책연구원 2019 정책연구 Vol.- No.-
The purpose of this study is to comprehensively analyze the impact of science and technology on jobs, and to lay the foundation for future technological developments to lead to the creation of decent jobs. First of all, this paper analyzes the employment impact mechanisms of science and technology, focusing on recent literature analysis, and summarizes the stages and major types of technological development or innovation activities that affect the employment of firms. Second, we analyze key industry cases by type of corporate response strategy to the employment impact of technological development. - Cases focused on improving process efficiency due to digitalization: logistics industry - Examples of business model innovations, such as manufacturing services or entering new businesses: New Space - Collaboration between Humans and Machines: Changes in Healthcare Jobs Third, we analyze the effects of technological development in the domestic labor market and draw policy implications through the analysis of job changes in Korea centered on science and technology profession and the employment impact of corporate R&D investment. Lastly, by analyzing the current status and limitations of Korea’s fourth industrial revolution response policy, we draw implications for policy improvement direction, and suggest strategies and comprehensive policy plans to promote the creation of decent jobs through the development of science and technology.