Z세대 대상 복합문화공간 사용자 경험 비교 연구 - 하우스 도산과 누디트 익선을 중심으로 -

이서후 ( Yi Seohoo ),김승인 ( Kim Seung In ) 한국상품문화디자인학회 2024 상품문화디자인학연구 Vol.77 No.0

코로나-19 이후 급성장한 복합문화공간의 주 고객층은 MZ세대이다. 이때 Z세대는 M세대와는 다른 소비 특성을 보이지만, 이를 분류하여 사용자 경험을 연구한 것은 부족하다. 본 연구는 국내 공간 사용자 경험 디자인 및 Z세대의 소비 성향에 관한 연구 183건을 메타 분석하여, 총 6가지 요인 범주(구조적, 시각적, 기능적, 사회문화적, 서비스적, 감성적)와 26가지 하위 요인을 추출하였다. 그중 Z세대의 가치 소비에 특화된 13가지 요인(접근성, 미학성, 혁신성, 유연성, 참여성, 상호작용성, 감성성, 경험성, 즐거움성, 지속가능성, 환경성, 정체성, 독창성)을 선정하였으며, 사례 검증을 통하여 ‘하우스 도산(Haus Dosan)’과 ‘누디트 익선(Nudit Ikseon)’ 두 공간을 분석하고, 그 사용자 경험을 평가하였다. 이때 두 공간 모두 방문한 경험이 있는 Z세대 60명을 대상으로 정량적 평가(온라인 구글 서베이)를 시행하였고, 이 중 8명을 대상으로 심층 인터뷰를 시행하였다. 이를 통해 도출한 결론으로는 첫째, Z세대의 환경적, 가치적, 지위적 의식에 관련된 경험(경제적, 쾌락적, 상징적, 관계적)을 기반으로 한 복합문화공간의 사용자 경험 평가가 유의미하며 가능하다는 것, 둘째, 복합문화공간에서 문화 및 전시 장소의 혁신성보다 즐거운 소비 경험 및 경제성이 중요하다는 점, 셋째, 재방문에 가장 큰 영향을 미치는 범주는 감성적 요인이라는 점이 있었다. 이처럼 본 연구는 Z세대의 소비 특성에 주목한 평가 방법을 제안하여 그 사용자 경험을 측정하고, 구체적인 제안 사항을 도출하였다는 점에서 의의가 있다. This study conducted a meta-analysis of 183 domestic research papers on spatial user experience design and the consumption tendencies of Generation Z, extracting a total of 6 categories (structural, visual, functional, socio-cultural, service-related, and emotional) and 26 sub-factors. Among these, 13 factors (accessibility, aesthetics, innovation, flexibility, engagement, interactivity, emotionality, experientiality, enjoyment, sustainability, environmental integration, and identity creativity) were specifically chosen for their relevance to the value-driven consumption patterns of Generation Z. This study performed Case validations through an analysis of the user experiences at 'HAUS DOSAN' and 'NUDIT Ikseon'. A quantitative evaluation involving 60 members of Generation Z was conducted using an online Google survey, complemented by in-depth interviews with 8 participants. The findings reveal that firstly, it is feasible to assess the user experience of multifaceted cultural spaces based on Generation Z's environmental, value-based, and status-related consciousness (economic, pleasurable, symbolic, and relational experiences). Secondly, within these spaces, enjoyable consumption experiences and cost-effectiveness are more crucial than the innovativeness of the culture and exhibition venues. Thirdly, emotional factors are the most significant in influencing revisits. Thus, this study highlights the importance of tailoring user experience assessments to the consumption characteristics of Generation Z, offering concrete improvements and recommendations.

내시경직시하 세침흡인세포진검사로 진단된 상부위장관종양

신현승,강진경,박인서,문영명,정재복,박찬일,송시영,정진이,임현이 대한소화기내시경학회 1993 Clinical Endoscopy Vol.13 No.2

The endoscopic fine needle aspiration cytology may add to the diagnostic accuracy of endoscopic biopsy and brush cytology. It is also of particular value in submucosal, infiltrative and ulceronecrotic tumors. Endoscopic fine needle aspiration cytology was done with sclerotherapy needle(23 gauge) in. the 17 patients with submucosal tumor(18 cases), extrinsic compression(2 cases), infiltrative gastric cancer(one case) and cancer of the ampulla of Vater(one case) on the upper gastrointestinal endoscopy. Endoscopic fine needle aspiration cytology established the diagnosis in 6 cases(submucosal tumor of the stomach; 2 cases, submucosal tumor of the duodenum; one case, extrinsic mass of the duodenum; one case, infiltrative cancer of the stomach; one case, and the cancer of ampulla of Vater; one case) of 17 cases. There were negative results for malignancy in 7 cases and material insufficiency in 4 cases. Five cases of the positive results with endoscopic fine needle aspiration cytology were not diagnosed with endoscopic forceps biopsies. There was no complication. We conclude that endoscopic fine needle aspiration cytology is a simple and safe technique and is of particular value in submucosal tumor, extrinsic compression of the upper gastrointestinal tract by tumor, and infiltrative gastric cancer.

뇌졸중 위험인자를 가진 어지럼 환자에서의 확산강조 자기공명영상

강형구,윤유상,이진희,박인철,이경룡,정상원,구홍두,김승호 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Background: The management of vertiginous patients is a great challenge to emergency physicians. We evaluated the diagnostic value of a diffusion-weighted image(DWI) in differentiating central vertigo from the peripheral vertigo in patients who presented no neurological symptoms other than risk factors for stroke. Methods: From March 2000 to February 2001, we retrospectively analyzed the cases of 68 patients who visited the emergency department with symptoms of isolated vertigo and who had risk factors for stroke. DWIs, computed tomograms(CT), and medical records were reviewed, and the final diagnose, the DWIs and the CT readings, the risk factors for stroke, and the time it took waiting for a DWI or CT scan were analyzed. Results: Of the 68 patients, 21(30.8%) had central vertigo: 15 vertebrobasilar transient ischemic attacks(VB-TIA), 4 brain stem infarctions, 1 cerebellar infarction, and 1 cerebellopeduncular infarction. The DWI showed a 28.6% sensitivity, a 97.9% specificity, and an 85.7% positive predictive value in diagnosing central vertigo. It also had a 100% sensitivity in detecting infarctions. Conclusion: A DWI had a comparable sensitivity to MRI in detecting central vertigo and small, but potentially, lethal infarctions in our patient population. We recommend clinical application of DWI in the emergency department evaluation of isolated vertigo patients with risk factors for stroke.

디지털 매거진 사용자 경험 및 이용 행태 연구

김여린(Kim, Yeo Rin),김승인(Kim, Seung In),김이령(Kim, Yi Ryung) 한국디지털디자인협의회 2013 디지털디자인학연구 Vol.13 No.1

태블릿 PC 시장의 지속적인 성장과 그에 따른 디지털 콘텐츠의 수요 증대로 새로운 플랫폼을 통한 다양한 인쇄매체 대체용 콘텐츠가 보급되고 있다. 국내에서도 통합 매거진 앱 서비스 플랫폼을 통한 콘텐츠 유통 방식의 변화 등 급변하는 환경에서 대응 전략을 활발히 모색하고 있으나, 구체적인 현황 파악 및 분석이 제대로 이루어지지 않아 방향성을 정립하기에는 부족한 실정이다. 본 연구는 디지털 매거진의 사용자 경험 측면에서의 사용성 및 이용자의 행태를 분석하여, 매거진 콘텐츠가 사용자 경험에서의 개선 방향을 모색하는 데에 연구 자료로서 현재의 문제점 및 개선에 필요한 단서를 제시하였다. 태스크 병행 심층 인터뷰를 통해 사용자 경험을 평가하였고, 행태 연구를 병행함으로써 사용자의 환경을 고려한 유기적인 분석결과를 도출하고자 하였다. 디지털 매거진의 총체적인 사용자 경험 측면에서 향후 태블릿 PC용 디지털 콘텐츠 제작에 시사점을 제시하였다. 추후 성별, 연령, 충성도 등 더욱 세부적인 분류에 기준한 후속 연구를 통해 매체별 독자 특성이 뚜렷한 매거진 전반의 앱 서비스 개선에 실질적인 도움이 되기를 기대한다. According to the continuous growth of Tablet PC industry, a variety of digital contents have been popularized through new platform, which substitute for traditional printed media. Domestic market leaders are actively finding counterstrategies in the quickly changing market environment including changed forms of contents distribution, but there is not enough understanding of user experience under present condition. The goal of this study is to provide current problems and improve the necessary elements of digital magazine contents for the better user experience through analyzing usability, as well as user behavior in terms of UX. In parallel with In-depth Interviews with usability task, user behavior research is also implemented to draw contextual results reflecting user environments. This study may have implications on the future digital contents production for Tablet PC in term of UX. Through follow-up studies on segmented target readers classified with gender, age, loyalty, it is expected that this study will give practical assistance to magazine app service improvement.

Effects of Exercise Training and Selenium on MCT1 and MCT4 Protein Levels in Skeletal Muscles of Diabetic Goto-Kakizaki Rats

Seung-Seok Kim(김승석),Eun-Bum Kang(강은범),Hyun-Sub Eum(엄현섭),Bum-Su Kim(김범수),Yea-Hyun Lim(임예현),Joon-Young Park(박준영),In-Ho Cho(조인호),Yoo-Sung Oh(오유성),Yi-Sub Kwak(곽이섭),Joon-Yong Cho(조준용) 한국생명과학회 2008 생명과학회지 Vol.18 No.1

이 연구는 지구성 운동과 셀레니움 투여가 Goto-Kakizaki 쥐의 젖산수송 능력에 독립적으로 혹은 상호작용하여 영향을 미치는가를 구명하는데 그 목적이 있다. 실험동물들의 집단은 비교집단(n=10, SED), 지구성 운동집단(n=10, EXER), 셀레니움 투여집단(n=10, SELE)과 지구성 운동과 셀레니움 투여 병행 집단(n=10, COMBI)으로 분류하여 6주간 실험을 실시하였다. 6주간 실험 처치 후 체중은 비교집단에 비해 지구성 운동집단, 셀레니움 투여집단과 지구성 운동과 셀레니움 투여 병행 집단이 현저하게 감소하였으며 당 부하검사를 실시한 결과에서도 비교집단에 비해 지구성 운동집단, 셀레니움 투여집단과 지구성 운동과 셀레니움 투여 병행 집단이 90분과 120분 사이에서 혈당 수준이 유의한 낮은 것으로 나타났다. 간 글리코겐 수준은 비교집단과 셀레니움 투여집단에 비해지구성 운동집단과 지구성 운동과 셀레니움 투여 병행 집단이 유의하게 높은 것으로 나타났다. 가자미근과 족저근의 글리코겐 수준도 비교집단과 셀레니움 투여집단에 비해 지구성 운동집단과 지구성 운동과 셀레니움 투여병행 집단이 현저하게 높은 것으로 나타났다. 혈액 생화학 성분의 경우, 지구성 운동집단, 셀레니움 투여집단과 지구성 운동과 셀레니움 투여 병행 집단이 비교집단에 비해 고밀도 지단백 수준 증가와 함께 혈장 젖산, 혈청중성지방, 인슐린, 총 콜레스테롤과 HOMA-IR 수준이 현저하게 감소한 것으로 나타났다. 특히 혈청 중성지방수준은 지구성 운동집단과 지구성 운동과 셀레니움 투여 병행 집단이 셀레니움 투여집단에 비해 유의하게 낮은것으로 나타났다. 이 연구에 가장 중요한 결과는 혈당과 젖산 수송과 관련된 단백질 발현 수준이 6주간의 실험처치 후에 지구성 운동집단, 셀레니움 투여집단과 지구성 운동과 셀레니움 투여 병행 집단이 비교집단에 비해 가자미근의 MCT1과 미토콘드리아 MCT1 단백질 발현수준이 현저하게 증가하였다는 결과와 함께 가자미근과 족저근의 MCT4 단백질 발현 수준도 지구성 운동집단, 셀레니움 투여집단과 지구성 운동과 셀레니움 투여 병행 집단이 비교집단에 비해 현저하게 증가하였다는 결과이다. 이러한 결과를 근거로 볼 때 지구성 운동과 셀레니움 투여는 독립적으로 혹은 상호작용하여 혈당과 젖산수송 능력을 개선시키는데 도움이 된다는 것을 알 수 있으며 특히 인슐린 저항 특성과 함께 고젖산혈증을 나타내는 제 Ⅱ형 당뇨 환자들의 당뇨 처치를 위한 방법으로 활용할 만한 가치가 있는 것으로 생각된다. The purpose of this study was to determine the possible additive effects of endurance exercise train-ing (EXER) and selenium (SELE) on the improvements of glucose and lactate transport capacities in diabetic Goto-kakizaki rats. Animals either remained sedentary control (SED) or performed EXER orreceived SELE [5μmol kg body wt (-1) day (-1)], or underwent both EXER and SELE (COMBI), which lasted for 6 wk. Compared with sedentary control, EXER alone or the SELE alone group, or the combined treatment group had significant reduction in glucose response measured at 90 min and 120 min during an intraperitoneal glucose tolerance test (IPGTT) and body weight after 6week treatment. EXER alone, or combined group individually had significantly higher glycogen contents in liver com-pared with SED or SELE groups. EXER alone increased glycogen content in soleus and plantaris compared with SED, and this parameter was increased to greatest extent in the combined treatment groups compared with SED or SELE groups. EXER alone, SELE alone or COMBI, caused significant decreases in the plasma lactates, serum glucose, insulin, total cholesterol and HOMA-IR along with a significant increase in high-density lipoprotein cholesterol compared with SED. In addition, EXER or COMBI individually had significantly lower serum triacylglycerol compared with SED or SELE. With respect to protein expression related to glucose and lactate transport capacities, EXER alone, SELE alone, or COMBI increased in MCT1 and MCT4 protein level in soleus and plantaris. Furthermore, EXER alone, SELE alone or COMBI caused significant increases in mt MCT1 protein level in soleus and plantaris. The findings of the current study suggest that endurance exercise training and selenium treatment may provide therapeutic values to type II diabetic patients with peripheral insulin resistance and hyperlactatecemia by improving glucose and lactate transport capacities, leading to improvements in plasma lactate, serum glucose, insulin and lipid profiles (TC, TG, HDL).

The Determination of the Duration of Electroconvulsive Therapy-Induced Seizure Using Local Standard Deviation of the Electroencephalogram Signal and the Changes of the RR Interval of Electrocardiogram

Kim, Eun Young,Yoo, Cheol Seung,Jung, Dong Chung,Yi, Sang Hoon,Chung, In-Won,Kim, Yong Sik,Ahn, Yong Min The Korean Society of Biological Psychiatry 2020 생물정신의학 Vol.27 No.1

Objectives In electroconvulsive therapy (ECT) research and practice, the precise determination of seizure duration is important in the evaluation of clinical relevance of the ECT-induced seizure. In this study, we have developed computerized algorithms to assess the duration of ECT-induced seizure. Methods Subjects included 5 males and 6 females, with the mean age of 33.1 years. Total 55 ECT sessions were included in the analysis. We analyzed the standard deviation of a finite block of electroencephalography (EEG) data and the change in the local slope of RR intervals in electrocardiography (ECG) signals during ECT-induced seizure. And then, we compared the calculated seizure durations from EEG recording (EEG algorithm) and ECG recording (ECG algorithm) with values determined by consensus of clinicians based on the recorded EEG (EEG consensus), as a gold standard criterion, in order to testify the computational validity of our algorithms. Results The mean seizure durations calculated by each method were not significantly different in sessions with abrupt flattened postictal suppression and in sessions with non-abrupt flattened postictal suppression. The intraclass correlation coefficients (95% confidence interval) of the three methods (EEG algorithm, ECG algorithm, EEG consensus) were significant in the total sessions [0.79 (0.70-0.86)], the abrupt flattened postictal suppression sessions [0.84 (0.74-0.91)], and the non-abrupt flattened postictal suppression sessions [0.67 (0.45-0.84)]. Correlations between three methods were also statistically significant, regardless of abruptness of transition. Conclusions Our proposed algorithms could reliably measure the duration of ECT-induced seizure, even in sessions with non-abrupt transitions to flat postictal suppression, in which it is typically difficult to determine the seizure duration.

종자산업법 제정 이전의 우리나라 종자관리 법령과 제도의 변천

이승인(Seung-in YI),방문진(Munjin Bang) 한국육종학회 2020 한국육종학회지 Vol.52 No.S

The history of development of seed management in Korea can be broadly divided into the periods of pre-enlightenment (Joseon Dynasty), enlightenment, Japanese colonial occupation, after liberation, installation of the National Seed Supply Office, and the Seed Industry Act. During the Joseon Dynasty, quite a few agricultural books had been published. With the signing of the Korea-U.S. Trade Treaty in the late 19th century, the Agriculture and Livestock Experimental Station was established, and subsequently many varieties were introduced from the U.S. and tested in the station. The Agricultural Exemplary Testing Station, founded in Suwon by the Japanese Resident General in 1906 as a national agricultural research facility, was a hub in colonial agricultural research and food production. In order to expand agricultural productivity, the Regulations on Subsidization of Rice Seed Production was enacted in 1922. This carried out nation-wide seed production and supply projects, and established a seed multiplication system. After liberation, the seed management system of food crops was enacted under the Major Crop Seed Act (1962). The Agricultural Seeds and Seedlings Act (1962) was enacted for vegetables and other crops, and then the Seedlings Management Act (1973) replaced it. In 1974, the National Seed Supply Office was established as an institution that supplies high quality seeds for food self-sufficiency with support of the FAO and IBRD. Then, by introducing the variety protection system under the Seed Industry Act (1997), Korea was able to reform the national seed management system and prepare an opportunity to join the ranks of developed countries.

Exposure to Volatile Organic Compounds and Possibility of Exposure to By-product Volatile Organic Compounds in Photolithography Processes in Semiconductor Manufacturing Factories

Park, Seung-Hyun,Shin, Jung-Ah,Park, Hyun-Hee,Yi, Gwang-Yong,Chung, Kwang-Jae,Park, Hae-Dong,Kim, Kab-Bae,Lee, In-Seop Occupational Safety and Health Research Institute 2011 Safety and health at work Vol.2 No.3

Objectives: The purpose of this study was to measure the concentration of volatile organic compound (VOC)s originated from the chemicals used and/or derived from the original parental chemicals in the photolithography processes of semiconductor manufacturing factories. Methods: A total of four photolithography processes in 4 Fabs at three different semiconductor manufacturing factories in Korea were selected for this study. This study investigated the types of chemicals used and generated during the photolithography process of each Fab, and the concentration levels of VOCs for each Fab. Results: A variety of organic compounds such as ketone, alcohol, and acetate compounds as well as aromatic compounds were used as solvents and developing agents in the processes. Also, the generation of by-products, such as toluene and phenol, was identified through a thermal decomposition experiment performed on a photoresist. The VOC concentration levels in the processes were lower than 5% of the threshold limit value (TLV)s. However, the air contaminated with chemical substances generated during the processes was re-circulated through the ventilation system, thereby affecting the airborne VOC concentrations in the photolithography processes. Conclusion: Tens of organic compounds were being used in the photolithography processes, though the types of chemical used varied with the factory. Also, by-products, such as aromatic compounds, could be generated during photoresist patterning by exposure to light. Although the airborne VOC concentrations resulting from the processes were lower than 5% of the TLVs, employees still could be exposed directly or indirectly to various types of VOCs.

Mineralized hyaluronic acid nanoparticles as a robust drug carrier

Han, Song-Yi,Han, Hwa Seung,Lee, Sang Cheon,Kang, Young Mo,Kim, In-San,Park, Jae Hyung Royal Society of Chemistry 2011 Journal of materials chemistry Vol.21 No.22

<P>Hyaluronic acid nanoparticles (HA-NPs), mineralized by calcium phosphate, were synthesized as a robust carrier of the anticancer drug, doxorubicin (DOX). The HA-NPs were readily mineralized in the presence of calcium nitrate and ammonium phosphate, which was confirmed by various instruments such as FT-IR, thermogravimetric analysis, transmission electron microscopy, and energy-dispersive X-ray photoelectron spectroscopy. Mineralization reduced the particle size of the HA-NPs in PBS (pH 7.4) from 263 nm to 142 nm, indicating the formation of compact nanoparticles. Mineralized HA-NPs were highly stable at pH 7.4, whereas their particle size rapidly increased in a mildly acidic solution, which was due to the dissolution of calcium phosphate. When DOX-loaded bare HA-NPs were exposed to buffer solutions of various pH, most of the DOX (>80%) was released within 48 h, and the release behavior was not dependent upon the pH of the solution. Notably, the mineralized HA-NPs released DOX in a sustained manner at pH 7.4, whereas a rapid release of DOX was observed in the acidic solution. The release rate of DOX from the mineralized HA-NPs was higher in the solution with a lower pH. These results indicate that mineralized HA-NPs have potential as robust nanoparticles that can release DOX at specific sites under mildly acidic conditions, such as in the extracellular matrix of tumor tissue and in intracellular compartments (<I>e.g.</I>, endosome and lysosome) of the cell.</P> <P>Graphic Abstract</P><P>The mineralized hyaluronic acid nanoparticles have potential as the robust carrier that can release hydrophobic drugs at specific sites under mildly acidic conditions. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1jm10466g'> </P>

Synergistic Anti-Tumor Effect of Sirolimus and Metformin in Colon Cancer Cell Lines -Suggested Regimen for the De Novo Colon Cancer after Liver Transplantation

( Nadiar Mussin ),( Seung Cheol Oh ),( Kwang-woong Lee ),( Min Young Park ),( Soo In Seo ),( Nam-joon Yi ),( Hyeyoung Kim ),( Kyung Chul Yoon ),( Sung-woo Ahn ),( Hyo-sin Kim ),( Suk Kyun Hong ),( Don 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: Post-transplant de novo malignancy is one of the leading causes of late mortality after liver transplantation (LT). Colon cancer has been reported as one of the frequent de novo cancer in Asia. However, there is no optimal treatment strategy for de novo colon cancer after LT. The objective of this study was to provide theoretical background of optimal immunosuppressant (IS) strategy for de novo colon cancer. Methods: Three colon cancer cell lines (HT29, SW620 and HCT116) were used in in vitro studies. HT29 was also used in BALB/c-nude mice animal models. Following groups were used in both in vitro and in vivo studies: sirolimus (S), tacrolimus (T), cyclosporin A (CsA), metformin (M), metformin/sirolimus (MetS), metformin/tacrolimus (MetT), and metformin/cyclosporin A (Met CsA). 3-(4 5-Dimethylthiazol- 2-yl)-2 5-diphenyltetrazolium bromide (MTT) assay was performed and Western blot analyses were performed for mTOR pathway proteins, apoptosis proteins, and EMT proteins. Tumor volume was measured for 4 weeks after inoculation. Results: MTT-assay revealed significant cell viability inhibition in all three colon cancer cell lines in groups of S, M, and Met/S. Of note, group Met/S showed synergistic effect compare to M or S group. Western blot analysis showed significant low levels of all investigated proteins in groups of S and Met/S in both in vitro and in vivo experiment. Tumor growth was significantly inhibited only in the Met/S group. Conclusions: Combination of Met and S showed the most potent inhibition in all colon cancer cell lines. This finding might have application for de novo colon cancer.