건축설계실무와 의사결정에 관한 사례 연구 : 공공프로젝트의 경우 Case of Buchon Welfare center and Yonsu Sub-municipal Office

장성준,서윤영,이현창,하종수 명지대학교 대학원 1997 대학원논문집 Vol.1 No.-

The study analyzes a series of decisions made by Building Construction Review Committee on public building construction project. Several government authorities are engaged on the review and required the building client authority to revise the design according to revise items suggested by the committee members ranging from Architectural Planning to other Building Engineering fields. The study delves the legal and design aspects of the review, the meaning of private, semi-public and public function of building, and the construction policy. Two Public building projects were analyzed in terms of revise items. We found some patterns of problem and the current review system works to promote technical aspect of the building and to keep public entity of the projects.

청소년의 인터넷 중독 정도에 따른 인적자원의 차이

장윤옥,정서린 경북대학교 사범대학 부속 중등교육연구소 2005 중등교육연구 Vol.53 No.2

본 연구의 목적은 청소년의 인터넷 중독 정도에 따른 이들의 인적자원의 차이를 알아보는 것이다. 본 연구는 396명의 중학교 2년생들을 대상으로 하였으며 연구방법으로는 질문지법을 이용하였다. 청소년들은 자신의 인터넷 중독 정도에 따라 인터넷 중독 집단, 인터넷 중독위험 집단, 인터넷 비중독 집단으로 나뉘어졌으며, 이러한 중독 정도에 따라 개인적 자원인 자기통제력, 시간관리, 문제해결능력과 대인적 자원인 부모 · 또래 · 교사지지에 차이가 있는지를 알아보았다. 본 연구결과 인터넷 중독 정도에 따라 개인적 자원에 유의한 차이가 있었는데 구체적으로는 인터넷 중독 청소년들이 비중독 청소년들보다 자기통제력과 문제해결능력이 통계적으로 유의하게 낮았으며, 시간관리능력도 차이가 있는 것으로 나타났으나 집단간 구체적인 차이는 통계적으로 유의하지 않았다. 또한 인터넷 중독 정도에 따라 대인적 자원에도 유의한 차이가 있었는데 구체적으로는 인터넷 중독 청소년들은 비중독 청소년들에 비해 부모, 또래, 교사로부터 지지를 더 적게 받는 것으로 지각하고 있었다. The purpose of this study was to investigate differences in human resource according to the degree of internet addiction of adolescents. The survey study administered 396 questionnaires to middle school students in Daegu. The adolescents were divided into three group - internet addiction group, internet mid-addiction group, and internet non-addiction group - by the degree of internet addiction. The data were processed using one-way ANOVA and Scheffe test for post-hoc analysis. The main findings of this study were as follows. First, The internet addiction adolescents were lower self-control and problem solving ability than internet non-addiction adolescents. Second, The internet addiction adolescents perceived lower support from parents, peers, and teachers than internet non-addiction adolescents.

위상최적화를 이용한 트레일러의 경량설계

안서욱,이신영,윤민수,장강원 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

A new design for a lightweight flatbed trailer with high bending and torsional stiffness is presented by using an integrated CAE-based optimization procedure. The integrated design procedure consists of two main steps: topology optimization and thickness optimization. During topology optimization, a creative frame layout different from existing ladder-type frames can be obtained by searching the best layout out of all possible layouts of a simplified design domain model. After approximating the result of topology optimization as a thin-walled structure, the approximated thicknesses of the plates are optimized to minimize the mass of a trailer.

카올린으로부터 질화알루미늄 분말 합성

이윤복,서기원,류봉기,김광호,박희찬,장윤식 釜山大學校生産技術硏究所 1996 生産技術硏究所論文集 Vol.50 No.-

카올린으로 부터 수화염기성황산알루미늄을 제조하고, 이것을 탄소열환원질화하여 질화알미늄 분말을 합성하였다. 수화염기성황산알루미늄은 카올린으로 부터 제조된 수화황산알루미나 0.5M 및 요소 5M인 용액으로 부터 얻은 것이 가장 미세하였다. 탄소열환원질화법으로 질화알미늄을 합성할 때 활성화탄과 염기성황산알루미늄의 질량비가 2인 조성이 가장 적합하였으며, 이 때 얻어진 질화알미늄은 0.3-1㎛의 submicron급 분말이었다. Aluminum nitride powder was synthesized by carbothermal reduction-nirtridation using kaolin- derived hydrated basic aluminum sulfate. The hydrated basic aluminum sulfate powder produced from the solution of 0.5M hydrated aluminum sulfate and 5M urea showed very fine particles. The aluminum nitride showed the submicron powder of 0.3-1㎛ in the optimum condition with 2.0-weight ratio of activated charcol to hydrated basic aluminum sulfate.

초산 수용액을 포함한 4성분계에서의 용제회수에 관한 연구

박동원,장윤식,최성욱,김영일,서진기 동아대학교 환경문제연구소 1998 硏究報告 Vol.21 No.1

Due to the rising cost of energy, new separation processes based on extraction are becoming more attractive than before. Thus, the need for calculating and predicting liquid-liquid equilibria(LLE) compositions has very much increased. The purpose of this study is to determine and describe LLE data for the quaternary system containing acetic acid aqueous solution and solvent at 25℃. We investigated that the selection of the optimum solvent to separate acetic acid from aqueous solution and compared with ternary and quaternary LLE including binary solvent also.

만성 C형 간염 환자에서 페그인터페론 알파2a와 리바비린 병합 치료중 발생한 벨마비 1예

김일환,장제혁,유충헌,최규남,고정해,김윤정,서광원,김지현,박성재,박은택,이연재,이상혁,설상영 인제대학교 2008 仁濟醫學 Vol.29 No.-

페그인터페론과 리바비린 병합요법은 만성 C형 간염의 일차 치료법이다. 저자들은 만성 C형 간염 환자에서 페그인터페론 과 리바비린 병합 요법 중에 발생한 벨마비 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. 환자는 5년 전부터 만성 C형 간염을 앓아온 48세 남자이며, PEG-IFN α-2a 135μgm 피하주사 주1회와 하루 1200㎎의 리바비린을 투여하였다. 치료시작 후 9개월째 환자는 오른쪽 안면의 근력약화를 호소하였으며 벨마비로 진단되었다. 페그인터페론과 리바비린 병합요법을 지속하면서 관찰하였다. 환자의 벨마비는 페그인터페론 치료를 중단하지 않았음에도 3개월후 증상이 회복되고 이후 벨마비 재발 없이 현재 경과관찰 중이다. 만성 C형 간염에서 페그인터페론과 리바비린 병합 요법시 벨마비의 발생 가능성을 염두에 두어야 하겠다. A Case of Bell's Palsy Associated with Combination Therapy of Pegylated Interferon Alfa-2a (PEG-IFN) and Ribavirin for Chronic Hepatitis C Virus Infection Pegylated interferon alfa(PEG-IFN α) and ribavirin therapy is the first line treatment for chronic hepatitis C. Mild complications of the therapy are common, but more serious complications are rare. We report here a case of Bell's palsy that occurred in a patient with chronic hepatitis C virus infection during combination therapy of PEG-IFN α-2a and ribavirin. The patient was 49-year-old man with chronic hepatitis C (genotype 1b) for 8 years. He had compensated liver cirrhosis with splenomegaly. Therapy with PEG-IFN α- 2a 135mcg/week and ribavirin 1200mg/day was initiated. After 9 months of the therapy, the patient showed a loss of muscular tone on the right side of his face. A diagnosis of Bell's palsy was made. The Bell's palsy resolved over 3 months despite continuation of the combination therapy.

재래식 시장 지하 상인의 호흡기증상 및 폐기능 조사 연구

이승관,이창규,조경진,임현표,서장훈,최윤수 高麗大學校 倂設 保健大學 保健科學硏究所 1998 保健科學論集 Vol.24 No.1

The prevalence of respiratory symptoms and pulmonary function were studied in a group of 55 whole-sale market merchants Working in underground. As a control group, 55 whitecollar workers was also included in this study. Following results were obtained. A higher complaint for respiratory symptoms(cough, sputum, chest tightness, shortness of breath) was found among merchants than control workers. The measurement value for FVC, FEV1.0, FEV 1.0% in the merchants were reveal to lower figure in comparison with control groups. The measurement Value for MVV, PEF in the merchants were lower than control groups, but was not significant statistically. The pattern of pulmonary ventilation disturbance in the whole-sale market merchant were the same as followings : restrictive disturbance(6 person), abstrictive disturbance(1 person), and combined disturbance(1 person).

Novel nanocrystal formulation of megestrol acetate has improved bioavailability compared with the conventional micronized formulation in the fasting state

Jang, Kyungho,Yoon, Seonghae,Kim, Sung-Eun,Cho, Joo-Youn,Yoon, Seo Hyun,Lim, Kyoung Soo,Yu, Kyung-Sang,Jang, In-Jin,Lee, Howard Dove Medical Press 2014 Drug design, development and therapy Vol.8 No.-

<P><B>Background</B></P><P>Megestrol acetate is an effective treatment for improving appetite and increasing body weight in patients with cancer-associated anorexia. However, Megace<SUP>®</SUP> oral suspension (OS), a micronized formulation of megestrol acetate, has low bioavailability in the fasting state. To overcome this limitation, a nanocrystal formulation has been developed. This study was performed to evaluate the pharmacokinetics and tolerability of the nanocrystal formulation and to compare them with those of Megace<SUP>®</SUP> OS in the fed and fasting states.</P><P><B>Methods</B></P><P>A randomized, open-label, two-treatment, two-period, two-sequence, crossover study was performed in three parts in 93 healthy subjects. A single 625 mg/5 mL oral dose of a nanocrystal formulation was administered in the fasting and fed states (part I). In parts II and III, a single 625 mg/5 mL oral dose of the nanocrystal formulation or Megace<SUP>®</SUP> OS 800 mg/20 mL was given in the fed and fasting states, respectively. Blood samples were collected for up to 120 hours post dose for pharmacokinetic analysis. Tolerability was evaluated throughout the entire study period.</P><P><B>Results</B></P><P>The nanocrystal formulation of megestrol acetate was rapidly absorbed in both the fed and fasting states. In the fed state, systemic exposure was comparable between the nanocrystal formulation of megestrol acetate and Megace<SUP>®</SUP> OS. In the fasting state, however, the peak plasma concentration and area under the plasma concentration-time curve to the last measurable concentration of megestrol acetate was 6.7-fold and 1.9-fold higher, respectively, for the nanocrystal formulation than for Megace<SUP>®</SUP> OS. No serious adverse events were reported.</P><P><B>Conclusion</B></P><P>Systemic exposure to megestrol acetate is less affected by lack of concomitant food intake when it is administered using the nanocrystal formulation. The nanocrystal formulation of megestrol acetate could be more effective in treating patients with cachexia or anorexia.</P>

Lenalidomide as a treatment for patients with AL amyloidosis and cardiac involvement

Seo Yoon Jang,Ja Min Byun,Sung-Soo Yoon,Jin Chul Paeng,Seung-Pyo Lee,Youngil Koh 대한혈액학회 2023 Blood Research Vol.58 No.4

Study on the Preliminary Design of ARGO-M Operation System

Seo, Yoon-Kyung,Lim, Hyung-Chul,Rew, Dong-Young,Jo, Jung-Hyun,Park, Jong-Uk,Park, Eun-Seo,Park, Jang-Hyun 한국우주과학회 2010 Journal of Astronomy and Space Sciences Vol.27 No.4