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( Sung Won Lee ),( Hae Lim Lee ),( Jung Hyun Kwon ),( Jun Suh Lee ),( Young Chul Yoon ),( Yu Ri Shin ),( Hye Ji Kim ),( Eun Chung ),( Young Woon Kim ),( Jeong Won Jang ),( Soon Woo Nam ),( Nam Ik Han 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1
Aims: Intraoperative radiofrequency ablation (RFA) is one of the treatment options for hepatocellular carcinoma (HCC) patients with relatively poor liver function to undergo surgical resection or when percutaneous approach for RFA is not feasible due to the difficult location of the tumor. The aim of this study is to investigate the clinical outcomes of intraoperative RFA compared to surgical resection. Methods: A total of 76 consecutive patients who received either intraoperative RFA (n=23) or surgical resection (n=53) with curative intent at the Incheon St Mary``s hospital from June 2012 to September 2015 were enrolled. Disease free survival and overall survival rates were analyzed. Results: The median follow-up period was 20.1 months (range, 0.9-41.5). The mean baseline Model for End-Stage Liver Disease (MELD) score was higher in the RFA group compared to the resection group (11.5±4.7 vs. 7.8±1.5, p=0.001). The resection group consisted of larger tumors with the median diameter of 2.7cm (range, 1-16) compared to 2cm (range, 1-5) of the RFA group (p=0.002). However, there was no difference in the number of tumors and the tumor stage between the two groups. The disease free survival rates at 6 and 12 months were 81.6%, 74.8% in the RFA group and 92.2%, 86.2% in the resection group, respectively (p=0.256). The overall survival rates at one year were 91.3% in the RFA group and 94.3% in the resection group, respectively (p=0.635). In the RFA group, 5 patients (21.7%) received liver transplantation (LT) after median interval of 10.9 months (range, 9.2~26.4) since the intraoperative RFA. Conclusions: The patients who received intraoperative RFA presented with relatively poor liver function but the disease free survival and overall survival rates were non-inferior compared to the patients who underwent resection. Therefore, intraoperative RFA may be considered as a useful option for patients ineligible to percutaneous RFA and surgical resection, or as a bridge therapy before liver transplantation.
A study on the optimal thickness of corn flakes produced by using the pressurized steam chamber
( Jun-sang Ahn ),( Jong-suh Shin ),( Min-ji Kim ),( Gi-hwal Son ),( Deok-yun Gil ),( Eung-gi Kwon ),( Byung-ki Park ) 한국축산학회(구 한국동물자원과학회) 2020 한국축산학회지 Vol.62 No.4
This study was conducted to evaluate the effect of the thickness of corn flakes produced by pressurized steam chamber (PSC) on rumen fermentation characteristics and nutrient degradability in Hanwoo and Holstein cows. Corn flakes were treated by PSC, in three groups based on corn flake thickness: < 2.5 mm (T1), 2.5-3.0 mm (T2), and > 3.0 mm (T3). Corn flake thickness significantly influenced pH (p < 0.01) and propionate concentration (p < 0.05) and slightly but not significantly influenced acetate, butyrate, and total-volatile fatty acids (T-VFA) concentrations. The dry matter (DM) degradability increased significantly with a reduction in corn flake thickness (p < 0.01), being significantly greater in T1 and T2 than T3 groups (p < 0.01) and similar between T1 and T2 groups throughout whole incubation time. Also, starch degradability was the lowest in T3 groups than others (p < 0.01). Thus, the present results showed that considering the production efficiency and economic feasibility, the optimal thickness of corn flakes produced in a PSC is recommended to be 2.5-3.0 mm.
Sang-Il Suh,Won-Kyoung Yoon,Tae-Jun Kim,Ran Choi,Chang-baig Hyun 한국임상수의학회 2016 한국임상수의학회지 Vol.33 No.4
An 8 month-old male Maltese (weighing 2.0 kg) was referred with loud heart murmur at routine physicalexam in local animal clinic. Electrocardiogram found left ventricular hypertrophy pattern (4.5 mV R-wave). Diagnosticimaging studies revealed the elongation of left ventricle (LV) with classic triple bumps on the main pulmonary artery,aorta and left atrium on the ventrodorsal view of radiograph. Echocardiography revealed patent ductus arteriosus (PDA)duct and continuous turbulent shunt flow (maximal velocity 4.83 m/s) between the aorta and pulmonary artery withleft to right direction. The PDA in this dog was successfully closed through femoral vein (transvenous approach) usinga 5 mm Amplatz® Canine Duct Occluder. To the best of author’s knowledge, this is the first case of PDA occlusiontreated with Amplatz Canine Duct Occluder through femoral vein.
Jun Sung Kim,LEESUBIN,Seung Wan Suh,Jong Bin Bae,Ji Hyun Han,Seonjeong Byun,Ji Won Han,Jae Hyoung Kim,Ki Woong Kim 대한뇌졸중학회 2020 Journal of stroke Vol.22 No.1
Background and Purpose Both hypertension and hypotension increase cerebral white matter hyperintensities. However, the effects of hypotension in individuals with treated hypertension are unknown. We analyzed the association of low blood pressure with the location and amount of white matter hyperintensities between elderly individuals with controlled hypertension and those without hypertension. Methods We enrolled 505 community-dwelling, cognitively normal elderly individuals from the participants of the Korean Longitudinal Study on Cognitive Aging and Dementia. We measured blood pressure three times in a sitting position using a mercury sphygmomanometer and defined low systolic and diastolic blood pressure as ≤110 and ≤60 mm Hg, respectively. We segmented and quantified the periventricular and deep white matter hyperintensities from 3.0 Tesla fluidattenuated inversion recovery magnetic resonance images. Results Low systolic blood pressure was independently associated with larger volume of periventricular white matter hyperintensity (P=0.049). The interaction between low systolic blood pressure and hypertension was observed on the volume of periventricular white matter hyperintensity (P=0.005). Low systolic blood pressure was associated with the volume of periventricular white matter hyperintensity in individuals with controlled hypertension (F1,248=6.750, P=0.010), but not in those without hypertension (P=0.380). Low diastolic blood pressure was not associated with the volumes of white matter hyperintensities regardless of presence of controlled hypertension. Conclusions Low systolic blood pressure seems to be associated with larger volume of periventricular white matter hyperintensity in the individuals with a history of hypertension but not in those without hypertension.
Granular Cell Tumor in the Sartorius Muscle
Jun-Bum Kim(김준범),Kwang-Min Choi(최광민),Sai-Won Kwon(권세원),Jae-Hwi Nho(노재휘),You-Sung Suh(서유성),Jong-Seok Park(박종석) 대한정형외과학회 2014 대한정형외과학회지 Vol.49 No.1
과립 세포종은 신경계통에서 기원하는 연부 조직 종양이며 매우 드문 질환으로, 통증이 없는 단독 종괴로 나타난다. 과립 세포종은 인체 내 어떤 곳에서도 발생할 수 있지만 대부분은 피부, 구강 내, 호흡기, 소화기관에 발생하며 근육 내의 발생이 보고되는 경우는 매우 드물다. 저자들은 대퇴 전방부의 종물을 주소로 내원한 71세 남자 환자에서 발생한 봉공근 내부의 과립 세포종 1예를 경험하여 문헌 고찰과 함께 보고하는 바이다. Granular cell tumor, a soft tissue neoplasm that originates in the nervous system, is a very unusual tumor. Granular cell tumor appears as a solitary painless lesion, which can arise at virtually any body site, but is mainly found on the skin, oral cavity, respiratory tract or digestive tract. However, an intramuscular granular cell tumor is very rare. We report on a case of a granular cell tumor in the sartorius muscle in a 71-year-old male patient along with a review of the literature.
Toxic epidermal necrolysis associated with methazolamide treatment
( Sang Youl Yun ),( Jun Gyu Song ),( Moo Kyu Suh ),( Tae Jung Jang ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Toxic epidermal necrolysis (TEN) is rare life-threatening disease, characterized by extensive necrosis and detachment of the epidermis. The pathophysiology of TEN is still unclear. But drugs are the most important etiologic factors. More than 100 different drugs have been implicated. High risk dugs are antibacterial sulfonamides, aromatic anticonvulsants, allopurinol, oxicam non steroidal anti-inflammatory drugs, lamotrigine and nevirapine. This disease also has been often associated with methazolamide which is a sulfonamide derivative and carbonic anhydrase inhibitor used for lowering of intraocular pressure in glucoma. We report a case of TEN induced by methazolamide on the 63-year-old glaucomatous male patient who presented with multiple, pricking erythematous macules, patches with bullae on the face, trunk, both extremities involving erosive oral mucosa. He received IVIG and corticosteroid treatment, given initially as 5g IVIG daily for 3 days and intravenous 250mg methylprednisolone daily and later changed to oral methylprednisolone. New epithelialization appeared within 2 weeks, and the lesions gradually resolved. The patient was discharged with normal oral feeding 6 weeks after admission. He has remained in good health without recurrence of symptoms during 7 months of follow-up. Methazolamide should be prescribed with caution in Korean glucomatous patients.
( Sang Hee Suh ),( Youngjoon Suh ),( Sohee Kim ),( Jun-mo Yang ),( Gyungtae Kim ) 한국부식방식학회(구 한국부식학회) 2019 Corrosion Science and Technology Vol.18 No.2
The feasibility of using benzotriazole (BTAH) to inhibit pitting corrosion in the sprinkler copper tubes was investigated by filling the tubes with BTAH-water solution in 829 households at an eight-year-old apartment complex. The water leakage rate was reduced by approximately 90% following BTAH treatment during 161 days from the previous year. The leakage of one of the two sprinkler copper tubes was investigated with optical microscopy, scanning electron microscopy, energy dispersive spectroscopy, X-ray photoelectron spectroscopy, and X-ray diffraction analysis to determine the formation of Cu-BTA film inside the corrosion pits. All the inner components of the corrosion pits were coated with Cu-BTA films suggesting that BTAH molecules penetrated the corrosion products. The Cu-BTA film was about 2 nm in thickness at the bottom of a corrosion pit. A layer of CuCl and Cu<sub>2</sub>O phases lies under the Cu-BTA film. This complex structure effectively prevented the propagation of corrosion pits in the sprinkler copper tubes and reduced the water leakage.
A Case of Polyarteritis Nodosa Involving the Breasts
( Jun Hyeong Cho ),( Jeongmin Hong ),( Wonyong Jo ),( Yun-hong Cheon ),( Hyun-ok Kim ),( Sang-il Lee ),( Young Sun Suh ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Polyarteritis nodosa (PAN) is a necrotizing vasculitis of small- and medium-sized arteries affecting multiple organ systems. Generally, multi-organ involvement is more common than isolated organ involvement in classic PAN. A localized PAN involving breasts alone has rarely been reported. We describe an unusual case of a 72-year-old woman with a localized form of PAN manifested by acute onset of breast pain with fever. Ultrasonography of breasts showed increased echogenicity of subcutaneous fat tissue surrounding the arteries with wall thickening in both upper breasts. Excisional biopsy of left breast revealed leukocytoclastic small to medium-sized arteritis without giant cell infiltration, indicating PAN. Other imaging studies showed that there were no visceral organ involvements. We diagnosed a localized PAN involving breasts, and initiated corticosteroid and methotrexate. She rapidly responded to the treatment and has remained in clinical remission for 1 year.