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Bioconversion of Ginsenoside Rd into Compound K by Lactobacillus pentosus DC101 Isolated from Kimchi
Quan, Lin-Hu,Cheng, Le-Qin,Kim, Ho-Bin,Kim, Ju-Han,Son, Na-Ri,Kim, Se-Young,Jin, Hyun-O,Yang, Deok-Chun The Korean Society of Ginseng 2010 Journal of Ginseng Research Vol.34 No.4
Ginsenosides are the principal components responsible for the pharmacological and biological activities of ginseng. Ginsenoside Rd was transformed into compound K using cell-free extracts of food microorganisms, with Lactobacillus pentosus DC101 isolated from kimchi (traditional Korean fermented food) used for this conversion. The optimum time for the conversion was about 72 h at a constant pH of 7.0 and an optimum temperature of about $30^{\circ}C$. The transformation products were identified by thin-layer chromatography and high-performance liquid chromatography, and their structures were assigned using nuclear magnetic resonance analysis. Generally, ginsenoside Rd was converted into ginsenoside F2 by 36 h post-reaction. Consequently, over 97% of ginsenoside Rd was decomposed and converted into compound K by 72 h post-reaction. The bioconversion pathway to produce compound K is as follows: ginsenoside Rd$\rightarrow$ginsenoside F2$\rightarrow$compound K.
Bioconversion of Ginsenoside Rd into Compound K by Lactobacillus pentosus DC101 Isolated from Kimchi
Lin-Hu Quan,Le-Qin Cheng,Ho-Bin Kim,Ju-Han Kim,Na-Ri Son,Se-Young Kim,Hyun-O Jin,Deok-Chun Yang 고려인삼학회 2010 Journal of Ginseng Research Vol.34 No.4
Ginsenosides are the principal components responsible for the pharmacological and biological activities of ginseng. Ginsenoside Rd was transformed into compound K using cell-free extracts of food microorganisms, with Lactobacillus pentosus DC101 isolated from kimchi (traditional Korean fermented food) used for this conversion. The optimum time for the conversion was about 72 h at a constant pH of 7.0 and an optimum temperature of about 30°C. The transformation products were identified by thin-layer chromatography and high-performance liquid chromatography, and their structures were assigned using nuclear magnetic resonance analysis. Generally, ginsenoside Rd was converted into ginsenoside F2 by 36 h post-reaction. Consequently, over 97% of ginsenoside Rd was decomposed and converted into compound K by 72 h post-reaction. The bioconversion pathway to produce compound K is as follows: ginsenoside Rd→ginsenoside F2→compound K.
Hao Cui,He-Chun Quan,Ri Jin,Zhehao Lin 대한토목학회 2023 KSCE JOURNAL OF CIVIL ENGINEERING Vol.27 No.1
Flood susceptibility mapping is an important method for flood research. In this paper, we combine a backpropagation neural network (BPNN) with a genetic quantum algorithm (GQA) for the first time to develop flood susceptibility mapping. The area on the Chinese side of the Tumen River Basin was selected as the research object. A set of flood conditioning factors was selected based on relevant literature and an actual situation and then validated using the chi-square test and correlation analysis. Different weights were assigned using stepwise weight assessment ratio analysis. Finally, modeling and flood susceptibility mapping using GQA-BPNN. As a reference, the same work was performed with both the pure BPNN and optimized BPNN using a genetic algorithm (GA). The results show that the area under the curve, root mean squared error, Nash-Sutcliffe coefficient and percentage of bias are significantly better for the GQA-BPNN than for the BPNN and GA-BPNN and that the flood sensitivity maps constructed by the GQA-BPNN have more flood points in high flood sensitivity areas. Therefore, the GQA-BPNN method can be considered an effective method for flood susceptibility mapping.
면진시스템용 U형 강재댐퍼의 형상 개발에 대한 해석적 연구
권순일,오상훈,이상호,Quan, Chun-Ri,Oh, Sang-Hoon,Lee, Sang-Ho 한국강구조학회 2010 韓國鋼構造學會 論文集 Vol.22 No.1
면진기술은 건축물의 구조적 피해를 줄이고 진동에 민감한 구조물의 내진성능을 향상시키는 가장 효과적인 방법 중의 하나이다. 하지만 면진구조시스템에서 지진에너지를 흡수하는 댐퍼의 재료로서 자주 사용되었던 납의 환경오염문제가 대두되면서, 최근에는 친환경 재료인 강재를 사용하는 경우가 증가하고 있다. 본 연구에서는 면진시스템용 에너지흡수장치인 U형 강재댐퍼를 대상으로 비선형 유한요소해석을 수행하고 SS400 강재와 고인성강재를 사용한 댐퍼의 해석결과를 비교하여 사용강재의 재료적 특성의 차이가 댐퍼의 변형능력에 미치는 영향을 분석하며, 고인성강재를 사용한 댐퍼의 형상비, 두께, 폭에 따른 변형능력을 파악한다. 또한 고인성강재를 사용한 U형 강재댐퍼의 응력분포를 분석하여 응력분포에서 나타내는 문제점을 개선하기 위한 대책으로 댐퍼의 일부 구간에 개구부를 둔 새로운 형상을 제시하고 형상에 따른 변형능력, 내력특성 및 응력분포를 고려하여 최적형상과 설계식을 제안하고자 한다. Seismic isolation is one of the most widely implemented and accepted seismic protection systems to limit or avoid damages from unforeseeable earthquakes. As an energy absorption device, however, the supplemental lead itself tends to pollute the environment. Consequently, it is predicted that the use of lead would be controlled. Considering the pollution caused by lead, several researchers are interested in the viability of using steel in place of lead. In this study, first, based on the results of a non-linear finite element analysis, the excellent deformation capacity of a very tough steel damper was demonstrated by comparing it with that of the SS400 damper and determining the effects of main parameters (the aspect ratio, thickness, and width) on the deformation capacity. Second, an optimum shape and design equation for a U-shaped damper with an opening based on stress distribution was suggested.