캔터키 블루그래스에 의한 잔디 조성 기술 개발

이재필,조용인,서한용,이상재,김태준,한인송,김두환 建國大學校附設農業資源開發硏究所 2001 農資源開發論集 Vol.23 No.-

Seed sowing is the major method for the establishment of cool-season grasses at the soccer fields, golf courses, etc. Germination speed of kentucky bluegrass(Poa prantensis L.: KB) is much slower than the other cool-season grasses. This study was conducted to solve the problems at the early stage of establishment with KB. The best priming conditions of KB, drying method after soaking in the water, and covering materials will be selected. To reduce irrigation frequency and quantity for seed germination, seeds of KB were exposed to the different soaking temperature(4, 20, 25, 30℃). soaking durations(3, 6, 10, 13, 19, 23 days), storage periods(3, 6, 9 days), storage humidities(30, 50, 100%), shading rate(0, 50, 100%), drying methods(dry in the air, heating, mix soaked seed with profile=1:2), and covering materials(70% shade net, fiber net). The optimum soaking temperature and duration for the seed priming of KB were 20℃ and 10 days, respectively. The optimum storage period and humidity were 3 days and 100%, respectively, Under 50% shading, germination rate was the highest. In drying method after soaking, mixture of seeds and profile(1:2) was optimum for sowing. Using the thin fiber net as covering material after sowing was good for not moving seeds and improved germination speed and rate.

專門大學 食品加工科 模型敎科課程 修正開發 硏究

馬相朝,趙德鳳,金東弼,崔春淳,李松周 광주보건대학 1988 論文集 Vol.13 No.-

As a result of research on the present condition of the department relating to food at the junior college as of 1987 in our country, the number of the departments are 23 cases and the full-time professors are 132 persons and the number of students are 3,760 persons. This study can see that our country has attached importance to food science education as fourfold in the number of students comparing with that of 1971. The character of the curriculum is different according to its systems, but it has the subject that need to train the major technicians and graduating students advance into each field. Because of great many of students who are trained in a field of food science, it can be said that further the food industry and the development of food science have good prospects. Food science is recognized as important thing to everyone due to a serious problem of food in accordance with the population growth and gradual scientific propulsion of the national dietary life. With the basis of the analytical about the curriculum of the department relating to the food of university and junior college in internal and external and the result that is analyzed students and teachers' replies by the questionaire, this study makes out a model plan of te curriculum in junior college like table 14. Though the curriculum is ideal and perfective, as if it is not governed well nothing can be obtained, the other way also even though the curriculum is not perfect, if the mystery of management is praciced, a good results can be getting. Especially modern creative way of field practice makes students themselves set up purpose to learn and look for its meaning, and as experimenting and confirming their own thought and ability through solution of problem it helps to get developed and made up theirs own self. Therefore constitution of course of the field pratice is established centering around the experence of students to set studying purpose. It is continuously managed to do the ideal studying by change of a time and demand of society, and also should be recognized to build up ability that judge and decide as theorizing a lot of knowledge on the conceptional and theorical basis. In the way that the department of food processing at a junior college should improve, improvement of educational equipment is urgent, then the cost of equipment should be secured and the curriculum should be improved. Finally, thank for every junior college who cooperate with this study and such study for more better fixed curriculum will be continued after this report. So there will be sufficient results.

정신병적 증상이 동반된 기면병 1예

홍승철,송정민,정종현,권용실,한진희,이성필 大韓神經精神醫學會 2003 신경정신의학 Vol.42 No.5

Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness, cataplexy, sleep paralysis, hypnagogic hallucinations and disrupted nocturnal sleep. We report a patient with a diagnosis of schizophrenia who was subsequently diagnosed as narcolepsy. A case of a 22-year-old woman with concomitant narcolepsy and psychotic symptoms was discussed from a perspective of the diagnosis and therapeutic challenges, particularly on pharmcological treatment dealing with issues raised by their coexistence.

전수면박탈이 정상인의 생리기능과 인지기능에 미치는 영향

정종현,송후림,신윤경,한진희,이성필,홍승철 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

Objectives : Purpose of this study was to investigate physiological and neurocognitive effects of total sleep deprivation by using laboratory blood tests and the computerized neurocognitive function test in healthy subjects. Methods : Sixteen healthy volunteers participated in this study. Subjects were recommended to remain awake for 48 hour sunder continuous surveillance. Lab tests of cortisol, Prolactin, thyroid hormone, growth hormone, and immunoglobulin (IgG, IgA, IgM, IgD, IgE), CBC, BC and the Vienna test were performed before and after 48 hours of total sleep deprivation. Results : Concentration of T3 and T4 significantly increased after deprivation. In the reaction test, distribution reaction time significantly increased, and correct reaction significantly decreased. In the vigilance test, amount of correct reaction Signifi-cantly decreased, and the mean value of correct reaction time was significantly delayed. Level of fasting blood sugar, total protein, albumin, alkaline phosphatase and potassium significantly increased, respectively, except for the level of total bilirubin which was decreased. After total sleep deprivation, WBC counts significantly increased. Regarding immunoglobulin level, IgG,IgA and Ag M concentrations appeared to decrease, but the results were not statistically significant. Conclusion : The effect of total sleep deprivation on physiological function was significant in the level of thyroid hormone. Although statistically not significant, the results of growth hormone and the immune system showed a trend in relations to the effect oftotal sleep deprivation. Results of blood chemistry suggest that sleep dephvation may influence metabolism Of hepato-biliary system. Cognitive impairment was also seen in reactive and vigilant functions after total sleep deprivation.

제주도 양식넙치, Paralichthys olivaceus의 스쿠티카충병 발생 동향

진창남,이창훈,오상필,정용욱,송춘복,이제희,허문수 한국어병학회 2003 한국어병학회지 Vol.16 No.2

The research was carried out to know the occurrence trend of scuticociliatosis and mortality of fingerlings in flounder. The diseased fish were collected from on-land rearing farms and hatcheries of flounder in Jeju Island form January 1991 to December 2001. Occurrence of scuticociliatosis was about 10% of total occurred diseases for 1991 to 1996, but increased to 34.5% in 2001. Although monthly occurrence of seuticociliatosis was not related to season from 1999 to 2001, the highest occurrence was revealed in July and August. Mixed infections of bacteria including Vibrio sp., Edwardsiella tarda, Streptococcus sp., and Flexibacter sp., with seuticociliates were observed. Among the bacteria, Vibrio sp., was the highest frequency(40.1%), and the lowest one(10.1%) was Streptococcus sp., Mortality of fingerlings by seuticociliates was different sharply according to size of fish. Mortality of infected fingerlings below 7㎝ of total length was 53.8%, while that of normal fingerling above 7㎝ of total length was 13.2%. When fish were grown above 25㎝, mass mortality by seuticociliates infection was decreased markedly.

Risk Scoring System to Assess Outcomes in Patients Treated with Contemporary Guideline-Adherent Optimal Therapies after Acute Myocardial Infarction

Song, Pil Sang,Ryu, Dong Ryeol,Kim, Min Jeong,Jeon, Ki-Hyun,Choi, Rak Kyeong,Park, Jin Sik,Song, Young Bin,Hahn, Joo-Yong,Gwon, Hyeon-Cheol,Ahn, Youngkeun,Jeong, Myung Ho,Choi, Seung-Hyuk The Korean Society of Cardiology 2018 Korean Circulation Journal Vol.48 No.6

<P><B>Background and Objectives</B></P><P>A risk prediction is needed even in the contemporary era of acute myocardial infarction (AMI). We sought to develop a risk scoring specific for patients with AMI being treated with guideline-adherent optimal therapies, including percutaneous coronary intervention and all 5 medications (aspirin, thienopyridine, β-blocker, angiotensin-converting enzyme inhibitor or angiotensin receptor blocker, and statin).</P><P><B>Methods</B></P><P>From registries, 12,174 AMI patients were evaluated. The primary outcome was 1-year all-cause death or AMI. The Korea Working Group in Myocardial Infarction (KorMI) system was compared with the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX AMI), Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC), and Global Registry of Acute Coronary Events scores (GRACE) models.</P><P><B>Results</B></P><P>Ten predictors were identified: left ventricular dysfunction (hazard ratio [HR], 2.3), bare-metal stent (HR, 2.0), Killip class ≥II (HR, 1.9), renal insufficiency (HR, 1.8), previous stroke (HR, 1.6), regional wall-motion- score >20 on echocardiography (HR, 1.5), body mass index ≤24 kg/m<SUP>2</SUP> (HR, 1.4), age ≥70 years (HR, 1.4), prior coronary heart disease (HR, 1.4), and diabetes (HR, 1.4). Compared with the previous models, the KorMI system had good discrimination (time-dependent C statistic, 0.759) and showed reasonable goodness-of-fit by Hosmer-Lemeshow test (p=0.84). Moreover, the continuous-net reclassification improvement varied from −27.3% to −19.1%, the integrated discrimination index varied from −2.1% to −0.9%, and the median improvement in risk score was from −1.0% to −0.4%.</P><P><B>Conclusions</B></P><P>The KorMI system would be a useful tool for predicting outcomes in survivors treated with guideline-adherent optimal therapies after AMI.</P>

Electrical Storms in Patients with an Implantable Cardioverter Defibrillator

Pil Sang Song,June Soo Kim,신대희,박정왜,배기인,이창희,정동채,류동렬,온영근 연세대학교의과대학 2011 Yonsei medical journal Vol.52 No.1

Purpose: In some patients with an implantable cardioverter defibrillator (ICD), multiple episodes of electrical storm (ES) can occur. We assessed the prevalence, features, and predictors of ES in patients with ICD. Materials and Methods: Eighty-five patients with an ICD were analyzed. ES was defined as the occurrence of two or more ventricular tachyarrhythmias within 24 hours. Results: Twenty-six patients experienced at least one ES episode, and 16 patients experienced two or more ES episodes. The first ES occurred 209 ± 277 days after ICD implantation. In most ES cases, the index arrhythmia was ventricular tachycardia (65%). There were no obvious etiologic factors at the onset of most ES episodes (57%). More patients with a structurally normal heart (p = 0.043) or ventricular fibrillation (VF) as the index arrhythmia (p = 0.017) were in the ES-free group. Kaplan-Meier estimates and a log-rank test showed that patients with nonischemic dilated cardiomyopathy (DCMP) (log-rank test, p = 0.016) or with left ventricular ejection fraction < 35% (p = 0.032) were more likely to experience ES, and that patients with VF (p = 0.047) were less affected by ES. Cox proportional hazard regression analysis showed that nonischemic DCMP correlated with a greater probability of ES (hazard ratio, 3.71; 95% confidence interval, 1.16-11.85; p = 0.027). Conclusion: ES is a common and recurrent event in patients with an ICD. Nonischemic DCMP is an independent predictor of ES. Patients with VF or with a structurally normal heart are less likely to experience ES.

The Association of CHADS-P2A2RC Risk Score With Clinical Outcomes in Patients Taking P2Y12 Inhibitor Monotherapy After 3 Months of Dual Antiplatelet Therapy Following Percutaneous Coronary Intervention

Pil Sang Song,Seok-Woo Seong,Ji-Yeon Kim,Soo Yeon An,Mi Joo Kim,Kye Taek Ahn,Seon-Ah Jin,Jin-Ok Jeong,Jeong Hoon Yang,Joo-Yong Hahn,Hyeon-Cheol Gwon,Woo Jin Jang,Hyuck Jun Yoon,Jang-Whan Bae,Woong Gil 대한심장학회 2024 Korean Circulation Journal Vol.54 No.4

Background and Objectives: Concerns remain that early aspirin cessation may be associated with potential harm in subsets at high risk of ischemic events. This study aimed to assess the effects of P2Y12 inhibitor monotherapy after 3-month dual antiplatelet therapy (DAPT) vs. prolonged DAPT (12-month or longer) based on the ischemic risk stratification, the CHADS-P2A2RC, after percutaneous coronary intervention (PCI). Methods: This was a sub-study of the SMART-CHOICE trial. The effect of the randomized antiplatelet strategies was assessed across 3 CHADS-P2A2RC risk score categories. The primary outcome was a major adverse cardiac and cerebral event (MACCE), a composite of all-cause death, myocardial infarction, or stroke. Results: Up to 3 years, the high CHADS-P2A2RC risk score group had the highest incidence of MACCE (105 [12.1%], adjusted hazard ratio [HR], 2.927; 95% confidence interval [CI], 1.358–6.309; p=0.006) followed by moderate-risk (40 [1.4%], adjusted HR, 1.786; 95% CI, 0.868–3.674; p=0.115) and low-risk (9 [0.5%], reference). In secondary analyses, P2Y12 inhibitor monotherapy reduced the Bleeding Academic Research Consortium (BARC) types 2, 3, or 5 bleeding without increasing the risk of MACCE as compared with prolonged DAPT across the 3 CHADS-P2A2RC risk strata without significant interaction term (interaction p for MACCE=0.705 and interaction p for BARC types 2, 3, or 5 bleeding=0.055). Conclusions: The CHADS-P2A2RC risk score is valuable in discriminating high-ischemic-risk patients. Even in such patients with a high risk of ischemic events, P2Y12 inhibitor monotherapy was associated with a lower incidence of bleeding without increased risk of ischemic events compared with prolonged DAPT.

Bone Formation in a Rat Tibial Defect Model Using Carboxymethyl Cellulose/BioC/Bone Morphogenic Protein-2 Hybrid Materials

Song, Sang-Heon,Yun, Young-Pil,Kim, Hak-Jun,Park, Kyeongsoon,Kim, Sung Eun,Song, Hae-Ryong Hindawi Publishing Corporation 2014 BioMed research international Vol.2014 No.-

<P>The objective of this study was to assess whether carboxymethyl cellulose- (CMC-) based hydrogel containing BioC (biphasic calcium phosphate (BCP); tricalcium phosphate (TCP) : hydroxyapatite (Hap) = 70 : 30) and bone morphogenic protein-2 (BMP-2) led to greater bone formation than CMC-based hydrogel containing BioC without BMP-2. In order to demonstrate bone formation at 4 and 8 weeks, plain radiographs, microcomputed tomography (micro-CT) evaluation, and histological studies were performed after implantation of all hybrid materials on an 8 mm defect of the right tibia in rats. The plain radiographs and micro-CT analyses revealed that CMC/BioC/BMP-2 (0.5 mg) led to much greater mineralization at 4 and 8 weeks than did CMC/BioC or CMC/Bio/BMP-2 (0.1 mg). Likewise, bone formation and bone remodeling studies revealed that CMC/BioC/BMP-2 (0.5 mg) led to a significantly greater amount of bone formation and bone remodeling at 4 and 8 weeks than did CMC/BioC or CMC/BioC/BMP-2 (0.1 mg). Histological studies revealed that mineralized bone tissue was present around the whole circumference of the defect site with CMC/BioC/BMP-2 (0.5 mg) but not with CMC/BioC or CMC/BioC/BMP-2 (0.1 mg) at 4 and 8 weeks. These results suggest that CMC/BioC/BMP-2 hybrid materials induced greater bone formation than CMC/BioC hybrid materials. Thus, CMC/BioC/BMP-2 hybrid materials may be used as an injectable substrate to regenerate bone defects.</P>

Frequency of Killer Cell Immunoglobulin-like Receptors (KIRs) in Korean Patients with Chronic HCV Infection

Sung, Pil Soo,Choi, Hee Baeg,Kim, Su-Yeon,Hong, Sung Woo,Park, Chung-Hwa,Song, Myeong Jun,Lee, Sung Won,Yoo, Chan Ran,Choi, Sang Wook,Han, Nam Ik,Kim, Tai-Gyu,Yoon, Seung Kew The Korean Academy of Medical Sciences 2011 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.26 No.11

<P>Natural killer (NK) cells play an important role in innate immunity, especially in the response to viral infections, such as hepatitis C virus (HCV). Killer cell immunoglobulin-like receptors (KIRs) are the primary receptors of NK cells that mediate innate immunity. KIRs are also involved in acquired immunity, because some KIRs are expressed on the surface of certain subsets of T cells. In this study, the frequency of KIR genes, <I>HLA-C</I> allotypes, and combinations of KIR genes with their <I>HLA-C</I> ligands were evaluated in two different groups of the Korean population: controls and patients with chronic HCV infection. The study population consisted of 147 Korean patients with chronic HCV infection. The frequency of KIR2DS2 in patients with chronic HCV infection was 9.5% which was significantly lower than 19.5% of the control (<I>P</I> < 0.01). However, there were no significant differences in the frequency of other KIR genes, <I>HLA-C</I> allotypes or different combinations of KIR genes with their <I>HLA-C</I> ligands. This study can contribute to the further prospective study with a larger scale, suggesting the assumption that <I>KIR2DS2</I> might aid in HCV clearance by enhancing both the innate and acquired immune responses of people in Korea.</P>