음용수 중 유해화학물질에 대한 위해성 평가에 관한 연구 : Ⅱ 비발암성 화학물질을 중심으로

정용,신동천,김종만,박성은,양지연,이자경,황만식,박연신 한국환경독성학회 1995 환경독성보건학회지 Vol.10 No.1

The purpose of this research is to estimate a safe environmental level of human exposure to thresholding acting toxicants in drinking water and recommend the acceptable levels and management plans for maintaining good quality of drinking water and protecting health hazard. This research has been funded as a national project for three years from 1992 to 1995. This study(the second year, 1993-1994) was conducted to monitor 39 species of non-carcinogenic chemicals such as volatile organic compounds(VOCs), polynuclear aromatic hydrocarbons(PAHs), pesticides and heavy metals of drinking water at some area in six cities of Korea, and evaluate health risk due to these chemicals through four main steps (hazard identification, exposure assessment, dose-response assessment and risk characterization) of risk assessment in drinking water. In hazard identification, 39 species of non-carcinogenic chemicals were identified by the US EPA classification system. In the step of exposure assessment, sampling of tap water from the public water supply system had been conducted from 1993 to 1994, and 39 chemicals were analyzed. Indose-response assessment for non-carcinogens, reference doses(RfD) and lifetime health advisories (HAs) of lifetime acceptable levels were calculated. In risk characterization of detected chemicals, the hazard quotients of noncarcinogens were less than one except those of manganese and iron in D city.

지리산국립공원 심원계곡 생태경관 복원공사지역 식생 변화

정태준 ( Tae-jun Jung ),김연경 ( Yeon-Gyeong Kim ),김영진 ( Young-jin Kim ),정명희 ( Myung-hee Jung ),박경희 ( Kyoung-hee Park ),신창근 ( Chang-keun Shin ),박선홍 ( Seung-hong Park ),김영선 ( Young-sun Kim ) 한국환경생태학회 2021 한국환경생태학회지 Vol.35 No.3

본 연구는 지리산국립공원 심원계곡 생태경관 복원공사지역의 모니터링 결과를 분석하여 체계적인 복원관리를 도모할 수 있는 기초자료를 확보하는데 그 목적이 있다. 복원사업이 완료된 2017년도에 식생 모니터링을 위한 조사구 12개소와 대조구 4개소를 설치하였고, 2017년과 2020년의 상대우점치, 종다양도지수, 유사도 등의 변화를 분석하였다. 복원사업 시 수목이 식재되었던 조사구는 종다양도지수가 0∼1.4552로 나타났고, 대조구와의 유사도지수에서는 1개 조사구가 1.32%로 분석된 것을 제외하고 모두 0%로 나타났다. 조사구의 종다양도지수 및 유사도지수가 매우 낮은 것은 복원사업 시 식재된 수목이 고사하거나 멧돼지 피해, 유수에 의한 침식으로 유실되는 등의 영향으로 판단되었다. 반면 복원사업 시 수목이 식재되지 않은 미식재 조사구는 종다양도지수가 0.9538∼2.3222로 나타났고, 유사도지수는 최대 8.33%까지 분석되었다. 국립공원 생태경관 복원공사지역의 복원 공법 개발을 위한 장기 모니터링과, 미식재 조사구의 천이과정을 분석하는 지속적인 연구가 필요하다. This study aims to obtain basic data for systematic restoration by analyzing the monitoring results of the Shimwon Valley Ecological Landscape Restoration Project area in Jirisan National Park. In 2017, when the restoration project was completed, 12 monitoring plots and 4 control plots were installed for vegetation monitoring, and changes in the relative dominance, species diversity index and similarity between 2017 and 2020 were analyzed. The species diversity index of the surveyed areas where trees were planted during the restoration project was 0-1.4552, and the similarity index with the control group was 0% except for one survey area at 1.32%. The very low species diversity index and similarity index in the survey areas were attributed to the loss of trees planted during the restoration project due to death, damage by wild boars, or erosion by running water. On the other hand, the species diversity index was 0.9538-2.3222 in the monitoring plot where no tree was planted, and the similarity index was analyzed to be as high as 8.33%. It is necessary to continue the long-term monitoring for the development of ecological landscape restoration methods in the national park and analysis of the succession in monitoring plots where no trees were planted.

4년제 간호대학(과) 실습 비 및 실습기자재 표준안 개발을 위한 기초조사연구

신경림,박경숙,안양희,정승교,서연옥 성인간호학회 2003 성인간호학회지 Vol.15 No.2

To describe the states of the laboratory facilities, equipment and expenses for practice in a four-year nursing schools and to analyze mandatory requirements for laboratory facilities and equipment. Method: A descriptive survey research design was used. The participants were 49 of the 4-year nursing schools across the nation. The data were collected by e-mail. The return rate were questionnaires was 63.3%(n=31). Result: In 2001 the total expenses for laboratory practice were 21,865,230won and the average per student was 102,418won. Types of laboratories included single and complex. The mean size for laboratories was 318.7 m^2 and mean size for laboratories for fundamental nursing was 161.1m^2. The range for number of students in a laboratory class was 20-30 for eight universities(30.8%). Among required laboratory equipment, items that were mercury and aneroid sphygmomanometers for children, electronic sphygmomanometers. Bell type fetal stetho-scopes, sheepskin, beds for children, for gynecology, and electronic hilo beds. Among the elective equipment, items that were deficient in 50% of the universities were O^2 tents, and incentive spirometers. The number of items that needs to add to the equipment and 22 for elective equipment. Conclusion: A standardized mandatory list of equipment for laboratory facilities and expenses for practice in 4-year nursing schools needs to be developed.

동아시아에서의 HIV/AIDS 역학

신소연,최준용,김영근,박윤선,김연아,김명수,송영구,Shuzo Matsshita,Taisheng Li,Hsi-Hsun Lin,Patrick Li,김준명,동아시아 HIV 네트워크(East-Asia Network on HIV; EAN-HIV) 대한감염학회 2007 감염과 화학요법 Vol.39 No.1

목적 : 최근 동아시아에서의 HIV 감염자 수의 급속한 증가는 여러 가지 심각한 문제를 야기하고 있다. 따라서 이지역에서의 HIV/AIDS 역학에 대해서 정확한 조명 및 분석이 무엇보다 필요하다. 이에 저자들은 동아시아 HIV 네트워크(East Asia Network on HIV; EAN-HIV)를 통하여 동아시아 HIV/AIDS 유행의 시작, 변천 및 현황에 관하여 알아보고자 한다. 재료 및 방법 : 동아시아에 HIV/AIDS가 처음 유입된 1984년부터 2005년까지 한국, 일본, 중국, 대만, 홍콩의 HIV/AIDS 관련 역학 자료를 동아시아 HIV 네트워크(East Asia Network on HIV; EAN-HIV)를 통하여 수집하고 분석하였다. 결과 : 동아시아에서의 HIV/AIDS 유행은 1980년대 중반에 시작되었다. 2005년 말까지 한국에서는 3,829명, 일본에서는 7,078명(혈우병 환자 제외), 대만에서는 10,423명,홍콩에서는 2,825명의 HIV 감염자가 보고되 었으며, 중국에서는 141,241명이 보고되었으나 실제로는 84만명 이상의 감염자가 존재할 것으로 추정하고 있다. 주사마약사용, 혈장매매, 성접촉에 의한 감염이 주를 이루고 있으며, 감염자중 남자가 많고 20-30대가 다수를 차지하였다. 중국이나 대만의 경우에는 최근 감염자 수가 급증하고 있으며 주사마약사용에 의한 감염이 주로 문제가 되고 있는 반면, 한국, 일본, 홍콩의 경우에는 남성동성애자에 의한 전파가 주가 되고 있다. 동아시아에서 유행하는 HIV의 주 아형은 B, C, CRFO1_AE 형이며, 최근에는 CRF07_BC형이 확산되고 있다. 결론 : 동아시아의 HIV 감염률은 빠르게 증가하며, 또한 HIV/AIDS 역학도 빠르게 변화하고 있다. 이 지역의 유행은 중국이 부분적으로 커다란 영향을 미치고 있다. Background : Recent predictions of catastrophic epidemic surge of HIV infection in East Asia concern experts and governmental organizations. As in many other areas, countries in East Asia show diversities in their HIV epidemics, both geographically and temporally. However, they have similar regional, cultural and racial characteristics which allow them to have certain common factors. Having a clear picture of the current extent and feature of HIV/AIDS in this region is a very difficult task largely due to the fast pacing of expending epidemic and difficulty in data-sharing among countries in the region. Hence, we decided to study the epidemiologic feature of HIV/AIDS in East Asia through East Asia Network on HIV (EAN-HIV). Materials and Methods : The epidemiological patterns of HIV/AIDS in East Asian countries were investigated by collecting data through EAN-HIV. Results : The HIV/AIDS epidemic in East Asia started relatively late at mid 1980s. Since then, the number of newly infected HIV/AIDS cases has been steadily increasing with stiffer escalation in recent years. In China and Taiwan, IDU plays an important part in the swiftly growing HIV epidemics; however, in other regions like Korea, Japan, and Hong Kong, MSM (men who have sex with men) seems to be more of a problem. The major subtypes of HIV in East Asia are subtype B, C, and CRF01_AE, and rapidly evolving circulating recombinant forms (CRF) between subtypes such as CRF07_BC give dynamic change to the current status. Conclusion : The incidence of HIV/AIDS is rapidly increasing in East Asia. The epidemic pattern has undergone dynamic changes over time. China seems to be the leading source of HIV/AIDS epidemic in East Asia due to its large population and rapidly growing epidemics.

동일한 시료에 대한 국내 기관간의 STR 분석결과 비교 : STR 유전자좌 분석법의 표준화 설정을 위하여

박종태,신경진,양윤석,우광만,이숭덕,이승환,이정빈,정연보,조승희,한길로,한면수,홍승범 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

This paper described a collaborative exercise intended to see what kinds of short tandem repeat (STR) loci are used in different DNA typing laboratories in Korea and to compare their results for the demonstration whether uniformity of DNA profiling results from different laboratory could be achieved in Korea Laboratories were asked to test five tissue DNAs using methods routinely used in each laboratory and to report the results to the coordinating laboratory. The exercise demonstrated that each laboratory was using different STR loci for the typing with different STR numbers,2 VNTRS,36 STRs and amelogenin in total, and the direct comparison of the results from all the laboratory for the 18 loci could not be done as only one laboratory submitted typing results. Among 21 loci for which several laboratories submitted typing results, results for 14 loci were the same and results for the other 7 loci were different depending on the participating laboratory. D1S80, F13A01, D16S539, D21S11, D18S51, D3S1744 were the loci with different typing results. Even in the cases where commercial kits were used, the results were not the same depending on the machines used, that is the capillary electrophoresis or the gel based electrophoresis. The reason for the different results, points about the standardization of the methods arid the profiling data were described.

일부지역 중·고등학생들의 흡연실태 조사연구

신옥순,남철현,김복용,최연희,박선희,박경옥,구재희 慶山大學校 保健福祉硏究所 2002 保健福祉硏究 Vol.7 No.-

This study was conducted to examine aspects of middle and high school students' drinking and smoking with analysis of related factors. The subjects of this study was 540 students in Kyungbuk Province. Data were collected from July, 2002 to September, 2002. The results of this study can be summarized as follows. 1. 43.6% of the boy students experienced smoking, while 12.2% of the girl students experienced it. 5.3% of the students at academy schools experienced smoking, while 44.7% of the students at vocational schools experienced it. 11.4% of the middle school students experienced smoking, while 33.9% of the high school students experienced it. 15.5% of them who lived in towns or villages experienced smoking and 38.3% of them who lived in small or medium sized cities experienced it.37.5% of the students who belonged to the lower economic class experienced smoking and 20.7% of the students who belonged to the upper economic class experienced it. 24.0% of the students who belonged to the middle economic class experienced it. It appears that the respondents showed significantly different smoking experience rates by gender, school types, grades, the number of family members, residences, and economic classes. 2. 14.5% of the respondents who lived with grandparents and parents experienced smoking and 26.5% of them who lived with parents experienced it. The smoking rate was significantly high in the groups of having one-parent, being unsatisfied with family life, making poor grades in studies, and having the father or the mother working as a salesperson. 3. 45.3% of the respondents who were unsatisfied with family life experienced smoking. The smoking rate of the respondents who were unsatisfied with it was significantly higher than that of the other groups. On the other hand, the smoking rates were not significantly different by daily life, schoolmate relation, health condition, and feeling stress. 4. According to smoking rate by frequency of drinking, 16.4% of the respondents who drank less than once a month smoked and 54.8% of them who drank more than twice a month smoked. The more frequently they drank, the higher their smoking rate was. Those who did exercise displayed significantly higher smoking rate than those who did not do exercise. Among the rates of the respondents' agonies, family disharmony was 50.5% and love problem was 39.2%. Economic condition preblem was 34.6%. It appeared that smoking was most influenced by the family disharmony. 5. The factors significantly influencing smoking experience were gender, school grade, schoolmate relation, score in studies, and exercise. From above results, it can be concluded that the students' smoking is a serious problems which can be resolved by simple approaches because it is interrelated complicatedly with gender, grade, family, school, etc. Schools, related organizations, and the government must closely work together to maximize the effectiveness of policy implementation concerning the smoking and drinking problem of the middle and high school students.

스포츠 현장에서 사고 분쟁해결을 위한 법적 구조 및 그 효용성 분석

박형상,육조영,김우규,이재봉,유관호,이무연,박태민,이신언 한국스포츠리서치 2005 한국 스포츠 리서치 Vol.16 No.2

1. The purpose of this study is to reflect reality of sports to legal structure. This author classified types of sports related accidents as match accidents, school accidents, leisure and living sports accidents. Out of such accidents common factors such as 'the provider of virtue' and 'user' could be deduced and this author reviewed what kinds of obligations must be shouldered by these people respectively. In particular this author stressed the fact that disproportionate emphasis is placed on malfeasance in disposition of dispute over the sports accidents. Malfeasance is a method for seeking relief through money after the accident. However default in an obligation enables supplementary completion when it is not performed or imperfectly performed. Thus if object which must be performed is providing safety then it is possible to secure safety prior to accident. Furthermore at such time mistake of the debtor can not become a factor. For this reason this line of thinking has the following merits: (1) In comparison with constitution of malfeasance default of an obligation has long prescription. It seems that such fact was a motivation for saving obligation for safety consideration by making it fall under the principle of faith. (2) Default of an obligation is not an obligation for ordinary attention which is cause of malfeasance but it takes up issue with obligation for attention required for performance. Game organization, sponsor and spectators etc. shares certain sense of identity and are demanded to have manners. As method for evaluation of such relationship of faith it may be possible to impose a special kind of obligation for attention and it will be close to constitution of default of an obligation. (3) Imposing obligation for provision clarifies that such responsibility belongs to game organizations promoting sports to which anyone can participates or to national or public organizations, sponsor, schools which induced such sports as a part of its educational programs, installer who made people use it as leisure facility or person in charge for its management. (4) It is also applicable to umpires, players or spectators who use field of sports. It is possible to reflect reality whereby these people specifically relate themselves to sports. In consequence it will be possible to make people feel the necessity of expanding the principals of sports from 'doers' to 'watchers.' (5) The obligation of provision is an obligation under the principle of faith therefore mutual negotiation may be expected to clarify such fact. It may be also evaluated by effectuation of users' self-determining right. 2. If the above mentioned structure is provided then, although it is limited to sports, students who are subjects of instruction, seminar attendants, and furthermore players who finished games may be obligated to bear responsibility for safety consideration under the principle of faith. Accordingly level of relief for considerable number of victims may be increased as cases of treating even borrowed materials as default of obligation being expanded. 3. As scope of responsibility becomes more clearer it will be possible to prevent disputes while securing more safety as rules and regulations become more clearly enacted or new contract is signed or existing contract is revised.

백서를 이용한 화학적 박피술의 실험적 연구

김수신,박성규,서연림,강신광 인제대학교 1991 仁濟醫學 Vol.12 No.2

화학적 박피술은 의학의 한 분야로 자리잡고 있음에도 불구하고 화학약품의 다양성과 시술 경험의 부족, 술기 표준화의 부족 등으로 인하여 의료인들의 적극적인 시술은 이루어지지 않고 있다. 저자들은 널리 쓰이는 화학 약품 사용해 백서에 화학적 박피술을 시행한 후 그 결과를 분석하여 하학적 박피술의 임상적용에 기초적 자료를 제공하고자 하였다. Chemical peeling has been used as a treatment of skin lesions coffined in epidermis and a portion of dermis, such as spotty hyperpigmentation, fine facial wrinkle, precancerous lesion, and superficial acne scar. We performed chemical peeling with widely used chemicals and results were as follows: 1.Depth of chemical peeling was consistent with neocollagen formation depth. 2.Mean depths of chemical peeling were 20% Resorcin : 0mm 20% Trichloroacetic acie : 0.12mm 35% Trichloroacetic acie : 0.22mm 50% Trichloroacetic acid : 0.47mm 50% Phenol : 0.52mm Baker's solution : 0.52mm 3.20% Resorcin had no peeling effect on dermis. 4.Trichloroacetic acid peeling had close relationship with concentration, and its peeling depth was consistent with necrosis depth. 5.50% Phenol showed no difference as compared with Baker's solution.

국내 대학병원에서 정주용 Ciprofloxacin 사용의 적정성 평가

김신우,박효정,오원섭,김연숙,장현하,정숙인,정두련,이혁,염준섭,기현균,손준성,백경란,우건조,송재훈 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

목적 : 국내 병원에서의 정주 ciprofloxacin 사용의 적정성을 평가하고자 하였다. 재료 및 방법 : 2003년 9월 25일부터 8개의 대학병원에서 정주 ciprofloxacin을 받았던 290명의 연속적으로 모집한 성인환자를 대상으로 약제사용 평가(DUE)를 전향적으로 수행하였다. 이 연구에 사용된 DUE 기준은 미국병원약사회의 기준을 국내 실정에 맡게 수정하여 사용하였으며 1) 사용의 정당성에 관한 항목, 2) 사용 시 준수되거나 시행되어야 할 사항에 대한 항목, 3) 부작용에 대한 항목, 4) 치료 효과에 대한 항목으로 나누어 조사하였다. 결과 : 환자의 평균 나이는 54세였다. 33예(26.9%)에서만 약제 사용의 적정성 측면에서 기준을 만족하였고 91예(73.1%)에서는 사용이 적절하지 않았다. 정주 cipro-floxacin의 부적절한 사용의 흔한 원인은 수술 전후의 예방약 사용, 비뇨기계 처치 전의 예방적 사용, 열성 질환에 대한 경험적 사용 등의 순이었다. 사용 시 준수사항 의 측면에서는 사용 전 배양검사(73.8%)와 사용 중 배양검사(68.6%)가 낮은 수행 정도를 보였으나 그 외는 비교적 높은 적정성(82.4-100%)을 보여주었다. 정주 ciprofloxacin사용의 합병증은 드물었다. 치료 효과의 면에서 치료반응은 93.3%였다. 결론 : 약제 사용의 정당성 기준에 따른 정주 cipro-floxacin의 부적절한 사용은 연구에 포함된 대학병원에서 매우 흔하였다(73.1%). 그러므로 적절한 항생제 사용에 대한 교육과 제도적 장치가 매우 필요한 것으로 판단되었다. Background : To evaluate the appropriateness of intravenous (IV) ciprofloxacin usage in university hospitals in Korea. Materials and Methods : We prospectively evaluated the appropriateness of drug usage in 290 consecutive adult patients who received IV ciprofloxacin in eight teaching hospitals during the period from September 25, 2003 to November 15, 2003. Drug use evaluation (DUE) in this study was based on the modified standard by the American Society of Hospital Pharmacy with regard to the justification of drug use, critical and process indications, complications, and outcome measures. Results : Average age of the patients was 54 years. The use of IV ciprofloxacin was appropriate only in 33 cases (26.9%). Common reasons for inappropriate use of IV ciprofloxacin include perioperative uses or prophylactic injection before urologic procedures, and empirical therapy for febrile episodes. Most of the "critical indications" and "process indications" showed high rate of appropriateness (82.4-100%). However, the rate of taking culture and sensitivity test before (73.8%) and during ciprofloxacin use (68.6%) were low. Complications with ciprofloxacin use were rare. In 93.3% of cases, ciprofloxacin treatment was clinically effective. Conclusion : Use of intravenous ciprofloxacin is frequently inappropriate in tertiary care hospitals in Korea. Implementation of education program and antibiotic control system is critical in improving the appropriateness of antimicrobial use.

다중지능 프로그램이 유아영재의 엉어, 수, 사회성에 미치는 효과

이신동,오연경,박지희 순천향대학교 인문과학연구소 2008 순천향 인문과학논총 Vol.22 No.-

The purpose of this study is to investigate the effect of a multiple intelligence program on the language, mathematics, and social behaviors of the gifted. The subjects were 20 gifted children who attended the Education Center in Seoul. They were 3-5 years old and their intelligence quotients were ranged between 125 and 140 measured by the K-WPPSI. Three tests were used in the study. First, the language ability test constructed by Young-Ae Jang (1981) was used for 4-6 years old children. Second, the test for the concept of numbers was designed to find out the achievement level of the number concept developed by Young-Hee Yeo (1995). Third, for the social behavior test questions that correspond to children aged between 3 and 5 were used. The results of this study were as followings: First, the multiple intelligence program positively affected the development of linguistic ability of the gifted children, with a significant difference in the development of linguistic expression. Second, the program based on multiple intelligence positively influenced the development of number concept of the gifted children. And third, multiple intelligence program has positively influenced the development of socialization of the gifted children, especiallv in terms of communication abilities.