천안지역 일부 다중이용시설의 포름알데히드 농도에 관한 연구

전혜리(Hye-li Jeon),조수연(Su-yeon Jo),조혜란(Hye-ran Jo),조태진(Tae-Jjn Cho),박종안(Jong-an Park),손부순(Bu-soon Son) 대한환경위생공학회 2009 대한환경위생공학회지 Vol.24 No.2

This study was conducted at a Terminal, a Parking Lot, an Underground shopping center, a Funeral hall and a Hospital waiting room of Cheon An area in August 2008 to examine the concentration level of HCHO(formaldehyde). The concentration level of the remodeled sites were 39.4 ± 12.0 ㎍/㎥ in the terminal, 32.7 ± 7.3 ㎍/㎥ in the parking, and 97.8 ± 29.4 ㎍/㎥ in the underground shopping center. The underground shopping center had the highest level and followed by the terminal and the parking. On the contrary, the site remodeling had the level of 17.7 ± 12.4 ㎍/㎥ in the funeral hall and 17.9 ± 0.6 ㎍/㎥ in the hospital waiting room. The funeral hall had highest level than that of the hospital waiting room. Both the remodeled sites and the not remodeled site had concentration level of HCHO below the standard level, but it was higher in the remodeled sites. There were no relations among the HCHO, the temperature and the humidity in facilities of Cheon An area.

Glass-ionomer 시멘트 이장재의 5급와동 치은측 변연폐쇄효과

박연준,손호현 全北大學校 齒醫學硏究所 1987 전북치대논문집 Vol.5 No.1

The purpose of this study is to evaluate the gingival margin sealing effect of glass-ionomer lining cements in Class V cavities. Freshly extracted 120 human teeth were divided into 4 groups. V-shaped cavity was prepared on the cervical area of facial surface of each tooth. Except the 1 ㎜ inner area from the gingival margin, exposed dentin surface was lined with Dycal in Group 1, Lining cement in Group 2 and Chembond cement in Group 3. No liner was used in Group 4. Prepared enamel surface in Group 1 and Group 4 was etched. In Group 2 and Group 3, prepared enemel surface and lined cement surface were etched simultaneously. After etching, washing and drying, bonding agent was applied and cured, and composite resin was inserted and cured with light in every cavity of teeth of all Groups. Restored teeth were thermocycled altenatively in 2% methlene blue dye solution of 4℃ and 60℃. After that, with diamomd disk under water spray, they were sectioned faciolingually to be divided equally. Dye penetration on the sectioned surface was observed with stereomicroscope. After statistical analysis, the following results were obtained : 1. There was significant difference in gingival margin sealing effect in lined cavities, except those lined with Chembond cement, compared with unlined cavities (p<0.01). 2. There was no significant difference in gingival margin sealing effect of glass-ionomer lining cements such as Lining cement and Chembond cement compared with that of Dycal (p>0.05).

葉煙草의 混植集團에 있어서 主要形質의 生態的 變異

孫錫龍,朴然圭 충북대학교 엽연초연구소 1983 煙草硏究 Vol.10 No.-

In the mixture planting ratio of tobacco cultivar Y.S.A. and Hicks were investigated on the variation of the leaf characters under field condition. Planting ratio of the above two cultivar were 100 : 0, 75 : 25, 50 : 50, 25 : 75 and 0 : 100 respectively. The results were summarized as follow. 1.Even though the growth characters of Y.S.A. and Hicks were different, the responses to mixture planting ratio were almost the same. The optimum mixture planting ratio of two cultivar for leaf length and leaf width were within a range of 100 % and 25 %, 2.The order of the mixture planting ratio for increases leaf length and leaf width of two cultivar was 100%>25%>75%>50%. 3.The ratio of leaf length to leaf width increased with 75 % mixture planting ratio, but its decreased lenearly with lower leaf position. Leaf length and leaf width of leaf decreased in relation to decreasing mixture planting ratio, but increaesd below a certain of mixture planting ratio. From theses results, it was concluded that mixture planting ratio with two cultivar is not necessary for a good growth of leaf length, leaf width and leaf area of the tobacco plant.

국내에서 발생하고 있는 사람 브루셀라증의 임상적 특성

김연숙,최영실,오원섭,권기태,이혁,이선희,손준성,김신우,장현하,정숙인,고관수,박미연,백경란,송재훈 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

배경 : 2002년 내국인에서의 첫 사람 브루셀라증의 증례 보고 이후 국내에서 사람 브루셀라증이 빠른 증가를 보이고 있다. 이에 연구자들은 국내에서 발생하는 브루셀라증의 임상적 특성을 연구하고자 하였다. 방법 : 2003년부터 2006년 7월까지 7개 대학병원에 내원한 환자들을 대상으로 WHO의 진단기준에 의하여 확진된 브루셀라증 환자들의 의무기록을 후향적으로 조사분석 하였다. 배양된 균은 삼성서울병원에 의뢰하여 16S rRNA 유전자 분석방법을 이용하여 종을 확인하였고, 표준시험관응집검사는 국립보건원에 의뢰하여 시행하였다. 결과 : 34예의 환자들이 브루셀라증으로 확진되었고, 31명이 남자였다. 혈액에서 B. abortus가 증명된 경우가 8예, 표준시험관 응집검사상 의미 있는 항체가 상승을 보인경우가 26예이었다. 환자들은 대부분 축산업관련 종사자였고, 추후 브루셀라증으로 확진된 소와의 직접 접촉을 통해 감염된 것으로 여겨진다. 국내 사람 브루셀라증의 가장 흔한 증상은 발열이었고, 위장관계 합병증이 가장 흔히 동반되었다. 치료로는 doxycycline/rifampicin이 24예의 환자에서 doxycycline/aminoglycoside (streptomycin 혹은 gentamicin)이 10예의 환자에서 6주 이상의 기간 동안 투여되었다. 치료에 반응을 보이지 않는 환자는 없었고, 재발이 1예 있었다. 결론 : 국내에서 발생하는 사람 브루셀라증의 원인균으로 현재까지 분리 동정된 것은 B. abortus이며, 소 브루셀라증의 증가로 인해 인체감염사례가 함께 증가하는 것으로 사료된다. 위험 직업군 종사자들에서 감염된 소와의 직접 접촉을 통해 주로 발생하고 있는 브루셀라증의 임상종상은 국외에서 발생하는 경우와 유사한 양상을 보이고 있으며 치료에 대한 반응은 비교적 좋은 편이긴 하나, 추후 보다 많은 환자들을 대상으로 한 연구가 필요하리라 사료된다. 사람 브루셀라증의 조절을 위해서는 소 브루셀라증의 조절이 필수적이며, 브루셀라증의 조절에 성공한 선진국의 사례를 적극적으로 도입해야 할 것으로 생각된다. Background : Since the first Korean case of human brucellosis was reported in 2002, the incidence of human brucellosis has been rapidly increasing. We performed this study to evaluate the clinical characteristics of human brucellosis occurring in South Korea. Materials and Methods : Demographic features, clinical manifestations, and therapeutic outcomes of cases confirmed as brucellosis according to WHO diagnostic criteria were evaluated. Species of Brucella isolates were identified with 16S rRNA gene sequencing method. Serologic diagnosis was performed with standard tube agglutination test (STA). Results : A total of 34 cases were enrolled from 2003 to 2006 in six hospitals. Eight cases were confirmed with the isolation of Brucella from blood and 26 cases were confirmed with titer of antibodies ≥1:160 by STA. Male (31) was predominant and most of the patients were cattle farmers. The most common transmission route was direct contact with infected or their cattle byproducts. Fever was the most prominent symptom and fatigue followed. Gastrointestinal and musculoskeletal systems were commonly complicated. Patients were treated with doxycycline and rifampin or aminoglycosides for more than 6 weeks. All patients responded well to the therapeutic regimens, but one patient relapsed 10 months after treatment. Conclusion : Brucellosis occurring in Korea has been caused by B. abortus, whose preferred natural host animals are cattle. Korean patients were infected through direct contact with bovine brucellosis. Clinical manifestations of brucellosis were similar to those occurring worldwide. Therapeutic outcomes were good among patients with brucellosis in Korea. In order to prevent human brucellosis, measures to eradicate bovine brucellosis should precede.

播種期, 苗令 및 土壤水分不足이 黃色種 담배의 生育 및 收量에 미치는 影響

盧載榮,申周植,朴然圭,孫錫龍 충북대학교 엽연초연구소 1984 煙草硏究 Vol.11 No.-

This experiment was conducted to study the influence of environment cultural method and their interaction on the growth and yield components of flue-cured tobacco. Applied variety was NC 2326, and was treated by sowing time(Mar. 11, Mar. 21 and Mar.31), seedling age (40,50 and 60 day) and soil moisture stress period (20 days from 10, 20 and 30 days after setting). The results are summarized as follows. 1.During growing period, stem height, length and width of the largest leaf and total leaves were affected remarkably by the treatments. 2.Soil moisture stress period affected more the characters of tobacco plants than other factors. 3.The tobacco plant treated by early stage soil moisture stress (period from 10 to 30 days after setting) made the early growth very poor, and that tobacco plant showed poor growth until 45 to 50 days after setting. 4.Early sowing, 40 day seedling and early stage soil moisture stress made the plant type sylindrical, and late sowing and 50 to 60 day seedling made the plant type cone shape. 5.Number of total leaves and harvested leaves, leaf area per plant percentage of dry matter of leaf and specific leaf weight decreased by the treatment of soil moisture stress during early and middle part of maximum growth stage. 6.There were little differences of yield among the treatment of different sowing time and seedling age. Early sowing increased the thickness of leaf and weight per unit leaf area, and decreased number of total leaves and specific leaf weight. Number of total and harvested leaves and specific leaf weight of cured leaves were high in the plot of 60-day seedling 40-day seedling showed heavy weight of unit leaf area and low specific leaf weight of cured leaves. 7.From the point of view of interaction between sowing time and seedling age, early sowing (Mar. 11) with 60-day seedling, middle sowing (Mar. 21) with 50-day seedling and late sowing (Mar. 31) with 40-day seedling are recommended. 8.Rapid growth of early growing stage was shown in the plot of adequate soil moisture and late sowing (Mar. 31) with 50-day to 60-day seedling. 9.From the point of standard quality of cured leaves, sowing time can be shifted until late March. And to fix the sowing time, It should be considered that the maximum growth stage and the harvesting time of cutter and leaf would not match with severe drought of May and rainy season of early summer respectively.

2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

Unwanted effects of risk notification for breast cancer regarding intention toward mammography utilization

Park, Keeho,Choi, Kui Son,Kye, Su Yeon,Park, Su Ho,Yoon, Nan He,Park, Eun Cheol John Wiley Sons, Ltd. 2010 PSYCHOONCOLOGY Vol.19 No.8

<P>Objective: This study was conducted to explore the possible influence of risk notification regarding breast cancer on the intention of women to undergo mammography.</P><P>Methods: This study employed an uncontrolled before–after design. A baseline survey was conducted in a random sample of 1000 women to examine the sociodemographic variables, breast cancer risk factors, and screening-related variables. All subjects received the findings of a personalized health-risk appraisal (HRA) following the baseline interview. After 2 months of the baseline survey, a survey was conducted in 855 women to assess whether the intention of undergoing mammography had changed. Thus, the modification in the intention by communicating the individual risk status was assessed.</P><P>Results: There was an overall increase from baseline to post-intervention in the number of subjects with the intention of undergoing mammography. Women in the contemplation and action stages who had intention toward mammography utilization at baseline showed decreased intention regarding mammography. After intervention in the form of HRA to promote mammography utilization, it was determined that young age, being married, being in neither the precontemplation nor the relapse stage, and having one or more risk factors of breast cancer were the predictors of intention to undergo mammography.</P><P>Conclusions: Our findings indicate that communicating the risk status by HRA service can have a negative effect in the promotion of health-conscious behavior. The selection of the appropriate type of intervention using HRA to promote mammography utilization in the target group will be enhanced by taking into account the risk status of each client. Copyright © 2009 John Wiley & Sons, Ltd.</P>

호흡기 질환 예방을 위한 멀티미디어 교육이 학령전기 환아의 지식 및 행위에 미치는 효과

손지영,박연홍,박미희,손은사,박진영,김순희 병원간호사회 2008 임상간호연구 Vol.14 No.1

Purpose: The purpose of this study was to identify the effects of multimedia educational program of the prevention of respiratory disorders on knowledge and behavior of preschool children. Method: The research design used a nonequivalent control group pre-posttest. 32 subjects in the control group received no intervention, 33 subjects in experimental group received a multimedia educational program that consists of video, named ‘The strong girl and weak girl’, 5 different picture boards, method of hand washing, tooth brushing, and reinforcement. The data were analyzed by using x2-test and t-test for determining of homogeneity and testing the hypothesis. Results: There were significant increases in knowledge and behavior in the experimental group compared to the control group. Conclusion: From the results of this study, the multimedia educational program significantly increased knowledge and behaviors of preschool children for preventing respiratory disorders. These findings suggest that a multimedia educational program can be used as an efficient nursing intervention of preschool children for preventing respiratory disorders.

Symposium 1 : Genomics and Bioinformatics ; Large Scale SNP Marker Discovery in a Korean Population Using MassARRAY

( Yeon Su Lee ),( Sook Young Kim ),( Jae Heup Kim ),( Kyung Hee Park ),( Yeon A Park ),( Ok Kyoung Son ),( Ji Young Jo ),( Kwang Sung Ahn ),( Yong Ick Ji ),( Joo Bae Park ) 한국생화학분자생물학회 (구 한국생화학회) 2002 추계학술대회집 Vol.2002 No.-

Heat Shock 70-kDa Protein 8 Isoform 1 Is Expressed on the Surface of Human Embryonic Stem Cells and Downregulated upon Differentiation

Son, Yeon Sung,Park, Jae Hyun,Kang, Young Kook,Park, Jin-Sung,Choi, Hong Seo,Lim, Ji Young,Lee, Jeoung Eun,Lee, Jung Bok,Ko, Myoung Seok,Kim, Yong-Sam,Ko, Jeong-Heon,Yoon, Hyun Soo,Lee, Kwang-Woong,Se Wiley (John WileySons) 2005 Stem Cells Vol.23 No.10

<P>The cell-surface markers used routinely to define the undifferentiated state and pluripotency of human embryonic stem cells (hESCs) are those used in mouse embryonic stem cells (mESCs) because of a lack of markers directly originated from hESC itself. To identify more hESC-specific cell-surface markers, we generated a panel of monoclonal antibodies (MAbs) by immunizing the irradiated cell clumps of hESC line Miz-hES1, and selected 26 MAbs that were able to bind to Miz-hES1 cells but not to mESCs, mouse embryonic fibroblast cells, and STO cells. Most antibodies did not bind to human neural progenitor cells derived from the Miz-hES1 cells, either. Of these, MAb 20-202S (IgG1, kappa) immunoprecipitated a cell-surface protein of 72-kDa from the lysate of biotin-labeled Miz-hES1 cells, which was identified to be heat shock 70-kDa protein 8 isoform 1 (HSPA8) by quadrupole time-of-flight tandem mass spectrometry. Immunocytochemical analyses proved that the HSPA8 protein was also present on the surface of hESC lines Miz-hES4, Miz-hES6, and HSF6. Two-color flow cytometric analysis of Miz-hES1 and HSF6 showed the coexpression of the HSPA8 protein with other hESC markers such as stage-specific embryonic antigen 3 (SSEA3), SSEA4, TRA-1-60, and TRA-1-81. Flow cytometric and Western blot analyses using various cells showed that MAb 20-202S specifically bound to the HSPA8 protein on the surface of Miz-hES1, contrary to other anti-HSP70 antibodies examined. Furthermore, the surface expression of the HSPA8 protein on Miz-hES1 was markedly downregulated upon differentiation. These data indicate that a novel MAb 20-202S recognizes the HSPA8 protein on the surface of hESCs and suggest that the HSPA8 protein is a putative cell-surface marker for undifferentiated hESCs.</P>