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      • KCI등재

        Elevational Distribution of Breeding Bird Communities in Seoraksan National Park, Korea

        ( Hyun-su Hwang ),( Jae-kang Lee ),( Tae-kyung Eom ),( Ho-kyoung Bae ),( Dong-ho Lee ),( Jong-hwan Lim ),( Sung-cheol Jung ),( Chan-ryul Park ),( Shin-jae Rhim ) 한국산림과학회 2020 한국산림과학회지 Vol.109 No.1

        In this study, the elevational distribution of breeding birds in Seoraksan National Park, Korea was investigated. Forty-six species of birds were documented from line transect surveys taken from Seorakdong at 230 m above sea level (a.s.l.) to the Daechungbong summit at 1708 m asl. Birdspecies richness and diversity were highest in Seorakdong and lowest at the Daechungbong summit. As elevation increased, bird species richness and diversity decreased, with a humped-shape trend being observed between 700 m and 1200 m a.s.l. Stepwise analyses revealed that breeding bird species diversity indices were significantly negatively correlated with elevation (r<sup>2</sup> = 0.327, P < 0.001) and positively correlated with vegetational coverage (r<sup>2</sup> = 0.324, P = 0.046). Higher elevations supported fewer birds than low and intermediate elevations. Projections at the local scale, including data on behavior and habitat use by birds, will be necessary for optimal conservation and management of the bird communities in Seoraksan National Park.

      • 내시경적 조임근절개술후에 발생한 췌십이지장 가성동맥류 1예

        박수영,김윤정,박진한,전현수,박시형,이영진,이은지,김지현 仁濟大學校 白病院 2010 仁濟醫學 Vol.31 No.-

        We reported a case of pancreatic pseudoaneurysm, involving pancreaticoduodenal artery, developed after endoscopic retrograde cholangiopancreatography(ERCP) with endoscopic sphinterotomy. A 54 year old woman was transferred to our hospital due to sustained hematochezia and hypovolemia. A week before admission, she underwent ERCP with endoscopic sphinterotomy for acute cholangitis in local clinics. She developed abdominal pain and hematochezia at 12 hours after the procedures. A post procedure contrast enhanced computed tomography of abdomen demonstrated a pseudoaneurysm in inferior portion of pancreatic head. This was not present on the pre procedure contrast enhanced computed tomography of abdomen and was thought to arise from the pancreaticoduodenal artery as a complication of the pre sphincterotomy. She was brought to our emergency room in a state of hypovolemia. A upper endoscopy showed active bleeding from ampula of vater. An celiac angiography demonstrated pancreatic pseudoaneurysm involving inferior pancreaticoduodenal artery and selective coil embolization of was performed.

      • KCI등재

        Elevational Distribution of Breeding Bird Communities in Seoraksan National Park, Korea

        Hwang, Hyun-Su,Lee, Jae-Kang,Eom, Tae-Kyung,Bae, Ho-Kyoung,Lee, Dong-Ho,Lim, Jong-Hwan,Jung, Sung-Cheol,Park, Chan-Ryul,Rhim, Shin-Jae Korean Society of Forest Science 2020 한국산림과학회지 Vol.109 No.1

        In this study, the elevational distribution of breeding birds in Seoraksan National Park, Korea was investigated. Forty-six species of birds were documented from line transect surveys taken from Seorakdong at 230 m above sea level (a.s.l.) to the Daechungbong summit at 1708 m asl. Birdspecies richness and diversity were highest in Seorakdong and lowest at the Daechungbong summit. As elevation increased, bird species richness and diversity decreased, with a humped-shape trend being observed between 700 m and 1200 m a.s.l. Stepwise analyses revealed that breeding bird species diversity indices were significantly negatively correlated with elevation (r<sup>2</sup> = 0.327, P < 0.001) and positively correlated with vegetational coverage (r<sup>2</sup> = 0.324, P = 0.046). Higher elevations supported fewer birds than low and intermediate elevations. Projections at the local scale, including data on behavior and habitat use by birds, will be necessary for optimal conservation and management of the bird communities in Seoraksan National Park.

      • Protein kinase A-induced phosphorylation at the Thr154 affects stability of DJ-1

        Ko, Yeon Uk,Kim, Su-Jeong,Lee, Juhyung,Song, Min-Young,Park, Kang-Sik,Park, Jun Bae,Cho, Hyun-Soo,Oh, Young J. Elsevier 2019 Parkinsonism & related disorders Vol.66 No.-

        <P><B>Abstract</B></P> <P><B>Introduction</B></P> <P>Most cases of Parkinson's disease (PD) are sporadic, but genetic variations have been discovered in PD patients. PARK7/DJ-1 is a known cause of early-onset autosomal-recessive PD and is implicated in neuroprotection against oxidative stress. Although several post-translational modifications of DJ-1 have been proposed, phospho-modification of DJ-1 and its functional consequences have been less studied.</P> <P><B>Methods</B></P> <P>Putative phosphorylation sites of DJ-1 were determined by liquid chromatography-tandem mass spectrometry (LC-MS/MS analysis). Subsequently, phosphorylation site of DJ-1 was confirmed by <I>in vitro</I> kinase assay and cell-based pull-down assay. Impaired dimer formation of phospho-null mutant was measured using DSS crosslinking assay and immunoprecipitation assay. To evaluate physiological consequences of this event, protein stability of DJ-1 WT and DJ-1 phospho-null mutant were compared using cycloheximide chase assay and ubiquitination assay.</P> <P><B>Results</B></P> <P>Here, we showed that DJ-1 directly bound to the catalytic subunit of protein kinase A (PKAcα). We found that PKAcα is responsible for phosphorylation of DJ-1 at the T154 residue. Interestingly, dimerization of DJ-1 was not detected in a DJ-1 T154A mutant. Furthermore, stability of the DJ-1 T154A mutant was dramatically reduced compared with that of wild-type DJ-1. We found that DJ-1 T154A was prone to degradation by the ubiquitin proteasome system (UPS).</P> <P><B>Conclusion</B></P> <P>We identified a novel phosphorylation site of DJ-1. Furthermore, we determined protein kinase A that is responsible for this posttranslational modification. Finally, we demonstrated physiological consequences of this event focusing on dimerization and protein stability of DJ-1.</P> <P><B>Highlights</B></P> <P> <UL> <LI> PKAcα phosphorylates PARK7/DJ1 at the Thr154 residue. </LI> <LI> Disruption of Thr154 phosphorylation is linked to a lower stability. </LI> </UL> </P>

      • Slide Session : OS-IFD-07 ; Infectious Disease : In Vitro Antiviral Activity of Ribavirin Against Severe Fever with Thrombocytopenia Syndrome Virus

        ( Myung Jin Lee ),( Kye Hyung Kim ),( Jong Youn Yi ),( Su Jin Choi ),( Chung Jong Kim ),( Nak Hyun Kim ),( Kyoung Ho Song ),( Pyoeng Gyun Choi ),( Ji Hwan Bang ),( Wan Beom Park ),( Eu Suk Kim ),( San 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1

        In Vitro Antiviral Activity of Ribavirin Against Severe Fever with Thrombocytopenia Syndrome Virus Myung Jin LEE1, Kye-Hyung KIM1, Jongyoun YI2, SuJin CHOI1, Chung-Jong KIM1, Nak- Hyun KIM1, Kyoung-Ho SONG1, Pyoeng Gyun CHOI1, Ji-Hwan BANG1, Wan Beom PARK1, Eu Suk KIM1, Sang-Won PARK1, Hong Bin KIM1, Nam Joong KIM1, Myoung- Don OH1 Seoul National University College of Medicine, Korea1, Pusan National University School of Medicine, Korea2 Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by a novel Bunyavirus, severe fever with thrombocytopenia syndrome virus (SFTSV). No effective antiviral therapy is proven yet, but clinical use of ribavirin (RBV) has been tried. We investigated the antiviral effect of RBV against SFTSV in vitro. Methods: To test for cytotoxicity of RBV, Vero cells were treated with different concentrations of RBV (3.90 to 500 μg/mL, two-fold dilution) and analyzed by cell viability MTS assay 48h post-infection. To determine antiviral activity of RBV against SFTSV, Vero cells were infected with SFTSV strain Gangwon/Korea/2012 at 100 TCID50 (50% tissue culture infective dose) per well in a 96-well plate, and RBV was added at the concentrations showing no or minimal cytotoxicity. Viral RNAs were extracted from the culture supernatants and quantifi ed using one-step real-time reverse transcription- PCR to amplify the partial large segment of SFTSV. Statistical analysis was done by one-way ANOVA with Tukey`s post hoc test. Results: Cytotoxicity due to RBV was not observed at RBV concentration =31.3 μg/ mL. Viral RNAs at 24h post-RBV treatment were reduced with increasing RBV concentrations (1-32 μg/mL), compared with those of mock-treated cells (P <0.01, Figure). Half maximal inhibitory concentration (IC50) of RBV was 3.69 μg/mL at 24h post-RBV treatment. Conclusions: Our study shows that RBV has antiviral effect against SFTSV in a dose-dependent manner. Further studies are required to evaluate the effi cacy of RBV in SFTS.

      • KCI등재후보

        국립공원 관리를 위한 해양생태계 장기 모니터링 프로그램의 발전 방향

        이채린(Chae-Lin Lee),유재원(Jae-Won Yoo),정병관(Byungkwan Jeoung),김창수(Chang-Soo Kim),안동식(Dong-Sik Ahn),김성태(Sungtae Kim),성은주(Eun-Ju Sung),김성현(Sung-Hyun Kim),정수영(Su-Yeoung Jeong),박영석(Young-Seuk Park) 국립공원연구원 2021 국립공원연구지 Vol.12 No.2

        생태계 변화의 모니터링은 효율적 생태계 관리를 위한 기초 정보 수집을 위해 중요한 과정이다. 많은 생태 현상과 그 과정은 오랜 시간에 걸쳐 진행되므로 국립공원의 지속적인 보전 및 효율적 관리를 위해 생태계 모니터링은 장기적으로 이루어질 필요가 있다. 본 연구는 국내외 장기 모니터링 프로그램 사례 분석을 통해 성공적인 장기 모니터링을 위한 방법으로써, 최적화된 모니터링 설계, 표준화된 운용방안 마련, 인적 자원 및 DATA 관리 체계 수립, 안정적인 재정 마련 및 후속지원 등을 제시하였다. 이를 바탕으로, 현재 10년 넘게 수행되고 있는 ‘HS호 유류유출 사고 해역 장기 모니터링 프로그램’의 발전 방향으로 적응형 모니터링 방식이 적용된 표준화된 프로토콜의 정립, QA/QC와 지속적인 자료 관리, 조사 항목의 연계성 강화 등의 구체적 방안을 제안한다. Monitoring ecosystem changes is an important process for collecting basic information for ecosystem management. Since many ecological phenomena and their processes take place over a long period of time, it is necessary to conduct long-term monitoring of ecosystems for the continuous conservation and efficient management of national parks. This study suggested an optimized monitoring design, standardized operation plan, human resource and data management system, stable financial preparation and follow-up support as methods for successful long-term monitoring through case analysis of domestic and foreign long-term monitoring programs. Based on this, it proposes specific measures such as establishing a standardized protocol with adaptive monitoring methods, continuous data management with QA/QC, and strengthening the linkage of investigation items in the development direction of the “HS oil spill accident long-term monitoring program” that has been conducted for more than a decade.

      • 衛生쓰레기 埋立場의 侵出水 特性分析에 관한 硏究

        朴炫建,成樂昌,徐珠洙 진주산업대학교 1990 論文集 Vol.28 No.-

        The results of Leachate from the Landfill site are as follows: 1. The polluation concentration of organic and inorganic matter arising from Leachate of landfillsite diminishes into the Logarthmic curve condition with the lapse of time. which makes the biological treatment diffcult 2. At an earlier stage of the landfill. Owing to the lack of the absolte guantity of PO_4 -P required for satisfying the ratio of BOD_5:PO_4 -P=100:1, PO_4 -P for biological treatment has to be supplemented artificially in proprotion to thne concentration of BOD. 3. As the pollustion concentration of NH_4 -N exceeds the limitation of the proper biological treatment(BOD_5: NH_4 -N), ammoniar-emoyed arrangements are needed for reducing the Stink before the biological treatment. Containing high concentration of NO_5 -N, the treated Leachate requires the fat-removed treatment. 4. The pollution concentration of the heavy metals in refuse can be reduced by regulating the pollution substances of heavy metals, the illegal landfill of the sludge form a factory, and so on.

      • Nd-Fe-B계 영구자석의 자기적 성질에 미치는 열처리의 영향

        朴現錞,徐守正 成均館大學校 科學技術硏究所 1991 論文集 Vol.42 No.1

        Alloys of 33%Nd-6.3%Fe-1.5%B-0.7%Al-0.6%Si were melted in vacuum induction furnace and quenched and ground to about 3㎛ sizes. After pressing these fine powders in magnetic field, sintering and annealing processes were performed in various temperatures. The measurement of magnetic properties of the processed alloys leads to the following conclusions. When the sintering temperatures were increased, the remanence of the alloys were increased slightly between 1060 and 1080℃ arid then were remained to be constant value of 10.3KG up to 1120℃. This is due to the effects of the presence of more Nd-rich phases as well as the presence of Al and Si in Nd-rich phase compared with the standard composition of Nd_15Fe_77B_8 which has a lower Nd-rich phase and contain no Al and Si. The optimum sintering temperature of the alloys was found to be 1080℃ and when the grains were hexagonal shaped and grain boundaries were linearly formed, the best magnetic property were obtained. When the alloys were annealed at about 520℃, the intrinsic coercivities were rapidly increased from 9 KOe to 12-14 KOe. Such increase was pronounced in the alloys sintered at 1060℃. But at the higher annealing temperatures the intrinsic coercivity was decreased in all the sintering temperatures. When the annealing were performed between 520 and 720℃, (BH)_max decreased in the lower temperature region but increased gradually as the annealing temperature increases. The is due to change of squarness and remanence.

      • 油菜의 酸處理에 따른 脂肪組成의 變化

        朴賢洙,吳成基 慶熙大學校 1987 論文集 Vol.16 No.-

        Rapeseed was treated with sulfuric acid solution for the purpose of removing glucosinolates, and changes in the fats and other compositions were examined. Four varieties of rapeseed were ground to 20-mesh, and each of those ground and intact varieties was treated with each of 0.5, 1.0 and 1.5 N-sulfuric acid solutions at 99±1℃ for 9 hours. Changes in the amounts of glucosinolates, total lipids, fatty acids and other compositions such as crude ash, crude protein, crude fiber and carbohydrates were measured. The recovery ratio of materials before ad after the acid treatment was 90%. The higher the acid concentration, the lower the recovery ratio. The content of glucosinolates and other compositions was significantly decreased with an increase of acid concentration, and the optical density of ground material was higher than that of the intact. Polar and nonpolar lipid contents were distinctively decreased when treated with 0.5N acid solution. Acid treatment did not give significant change in the fatty acid contents of crude oils and nonpolar lipids, whereas it slightly increased the content of desirable fatty acids.

      • 전류제어에 의한 단상유도전동기의 기동특성 개선

        박수강,최낙일,백형래,임양수,이기용,신사현 조선대학교 에너지.자원신기술연구소 1998 에너지·자원신기술연구소 논문지 Vol.20 No.1

        A single phase induction motor(SPIM) with two windings, main and auxiliary, is probably the most widely used motor in the world due to their ruggedness, low maintenance and simplicity of construction There are several ways of starting single phase motors The most popular arrangements is centrifugal switch An auxiliary winding connected in series with a capacitor, is brought into the circuit during starting The closing and opening of the switch must be speed dependant The switch meets the speed requirements, but it also has many drawback random switching, arcing, many models necessary for different speeds and shaft diameters, space required inside the motors and limited lifetime to name some of them. In this paper, the starting current of single phase induction motor was detected by a small detector and determined TRIAC gate signal. The strategy of current control is based on limited main and auxiliary current angle during starting period in the closed-loop control. The experimental result show the motor's starting characteristics of the proposal starting system and are compared with centrifugal switch starting motor.

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