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민경우,이경석,박옥현,윤관주,김도술,박세일,정원삼,이대행,조영관,Min, Kyoung-Woo,Lee, Kyoung-Soek,Park, Ok-Hyun,Yoon, Kwan-Ju,Kim, Do-Sool,Park, Se-Il,Jeung, Won-Sam,Lee, Dae-Hang,Cho, Young-Gwan 한국환경보건학회 2015 한국환경보건학회지 Vol.41 No.3
Objectives: This study aimed to survey the characteristics of air quality and meteorological conditions in a greenway park. Methods: We measured meteorological and health related factors, including noise, particulate matter ($PM_{10}$) and selected gaseous air pollutants at three locations in a greenway park and on a general roadside as comparison. The measurements were repeated four times from April to October 2014. Results: The average air temperature in the greenway park was $20.7^{\circ}C$ which was $1-2^{\circ}C$ lower than on the general roadside. The average $PM_{10}$ concentration in the greenway park was $85.0{\mu}g/m^3$, a level 2-3 times lower than that at the roadside. The noise level at the greenway site was 4.4 dB(A)- 23.0 dB(A) lower than at the roadside. The average CO, $CO_2$, $SO_2$ and NOx concentrations in the greenway park were lower than at the roadside. The average phytoncide and anions concentrations in the greenway park were higher than at the roadside. Conclusions: The urban forest of the greenway park may have some impact on air quality and meteorological conditions.
다세대주택 주거지와 아파트단지 주거지에서 양육자의 일상적 이용공간에 대한 접근성 비교분석
김효정(Kim, Hyo-Jeong),반영운(Ban, Yong-Un),박경옥(Park, Kyoung-Ok) 한국주거학회 2018 한국주거학회 학술대회논문집 Vol.30 No.1
The purpose of this study is to analyze walking accessibility to multi-family houses area and apartment complexes area using space syntax and discuss it from the viewpoint of child care environment. For this study, Bokdae1-dong and Gagyeong-dong that have the most infants in Cheongju City were selected as target places. Auto Cad 2018, depthmapX_0.35_windows, and SPSS 10.0 were used for analysis. Findings of this study are as follows: 1) Apartment complexes area is wider than multi-family houses area in a range of integration level. 2) For multi-family houses area, park/playground showed the highest integration level whereas children"s hospital showed the lowest one. For apartment complexes area, children"s hospital showed the highest integration level whereas park/playground showed the lowest one. However, there was no statistically significant difference. 3) When analyzing accessibility to spaces in multi-family houses area and apartment complexes area respectively according to blocks, it was found that there was a statistically significant difference in integration level of day care center, children"s hospital, and park/playground.
PARK, JI-WON,KWON, OK-KYOUNG,KIM, JUNG-HEE,OH, SEI-RYANG,KIM, JAE-HONG,PAIK, JIN-HYUB,MARWOTO, BAMBANG,WIDJHATI, RIFATUL,JUNIARTI, FIFIT,IRAWAN, DODDY,AHN, KYUNG-SEOP Spandidos Publications 2015 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.35 No.4
<P>Rhododendron album Blume (RA) has traditionally been used as an herbal medicine and is considered to have anti-inflammatory properties. In the present study, we screened RA extracts with anti-inflammatory properties. The biological effects of an RA methanol extract (RAME) on inflammation were investigated in lipopolysaccharide (LPS)-stimulated mouse RAW264.7 cells. We investigated the effects of RAME on the production of nitric oxide (NO) and prostaglandin E2 (PGE2) in LPS-stimulated RAW264.7 cells. To explore the anti-inflammatory mechanisms of RAME, we measured the mRNA and protein expression of pro-inflammatory mediators induced by RAME in the LPS-stimulated RAW264.7 cells by RT-PCR and western blot analysis, respectively. RAME significantly inhibited the production of NO, PGE2, interleukin (IL)-6, IL-1β and tumor necrosis factor (TNF)-α in the LPS-stimulated RAW264.7 cells. It also suppressed the mRNA and protein expression of inducible NO synthase (iNOS), cyclooxygenase-2 (COX-2) and mitogen-activated protein kinases (MAPKs) with a concomitant decrease in the nuclear translocation of nuclear factor-κB (NF-κB) in the LPS-stimulated RAW264.7 cells. These results indicate that RAME inhibits LPS-induced inflammatory responses. These effects were considered to be strongly associated with the suppression of NF-κB activation. We therefore suggest that RAME may be prove to be an effective therapeutic agent for the treatment of inflammatory diseases.</P>
Park, Ji-Won,Kwon, Ok-Kyoung,Jang, Ha-young,Jeong, Hyeok,Oh, Sei-Ryang,Lee, Hyeong-Kyu,Han, Sang-Bae,Ahn, Kyung-Seop Kluwer Academic/Plenum Publishers 2012 INFLAMMATION Vol.35 No.1
<P>The biological activity of Wercklea insignis (WI) in inflammation and the underlying mechanisms of action of extracts of this plant are largely unknown. In the present study, we investigated the effects of a WI methanolic extract on lipopolysaccharide-stimulated inflammation in the mouse macrophage cell line, RAW 264.7. A WI methanolic extract significantly inhibited NO, PGE(2), IL-6, IL-1β, and TNF-α production in LPS-stimulated RAW 264.7 cells. Expression of iNOS, COX-2, IL-6, IL-1β, and TNF-α were suppressed by the extract at both the mRNA and protein levels in lipopolysaccharide (LPS)-stimulated cells. Additionally, the attenuation of inflammatory responses in RAW 264.7 cells by the WI extract was closely associated with suppression of phosphorylation of mitogen-activated protein kinase (MAPK) molecules, including ERK, JNK1/2, and p38 MAPK and translocation of the nuclear factor (NF)-κB p65 subunit into the nucleus. The effect of WI extract was investigated against carrageenan-induced paw edema in female (20-25 g). Our results collectively indicate that the WI extract inhibits LPS-induced inflammatory responses by blocking the NF-κB signaling pathway in macrophages, supporting use of the extract as a therapeutic anti-inflammatory treatment.</P>
Park, Kyoung-Ok,Nam, Chul-Hyun 慶山大學校 保健福祉硏究所 2003 保健福祉硏究 Vol.8 No.-
지나친 음주나 문제 음주행위는 간질환을 비롯한 육체적 건강문제 뿐만 아니라 스트레스나 우울 등 정신건강문제와도 관련이 깊으며, 산업장 근로자에게는 문제음주에 따른 조직 생산성의 감소와 의료비 지출을 고려할 때 보다 신중하게 관리되어져야 한지만 음주, 스트레스, 업무특성, 개인특성 등 다양한 요인들이 복잡하게 얽혀있어서 이들 관계에 대한 전체적이고 간략한 흐름을 파악하기가 쉽지 않다. 본 연구는 근로자의 업무스트레스와 음주행위의 관계에 대한 전반적인 연구결과들을 정리하여 근로자 음주관리에 대한 대책을 마련하는데 그 기초자료를 제공하고자 한다. 지난 1988년부터 1998년 10년동안 보건관련 영문학회지에 실린 논문들을 중심으로 업무스트레스와 음주에 관한 기술적 문헌고찰을 시도하였다. 문헌추적을 위해 사용한 문헌검색 엔진은 'Medline'와 'Psychinfo'였다. 음주와 스트레스의 관계에 대해 논문의 70%는 단면적 연구였고 30%는 전향적 연구였는데, 스트레스의 개념적 한계 때문에 의학적 또는 역학적 접근이 매우 적었다. 고찰에 사용된 연구보고에 의하면 미국의 음주율이 대략 50-60%였으며, 적당량의 음주를 하는 군이 전혀 음주하지 않는 군이나 폭음이나 문제음주 행위를 가진 군보다 스트레스가 낮고 정신적으로 더 건강한 경향이 있었다. 스트레스와 음주행위는 그 단순상관관계가 전반적으로 0.2-0.3의 분포를 보여 약상관관계로 이해되었으며, 업무통제, 업무요구, 업무자율성, 업무분담의 명확성, 고용불안정이 유의미한 직장 스트레스 요인들이었다. 최근에는 조직문화, 조직이념 등의 업무 변수들이 추가되고 있었다. 음주와 스트레스 증상과의 관계에 영향을 미치는 간섭요인들로 결혼관계 갈등, 경제적 어려움, 인성특성, 사회적 지지도, 스트레스 생활사건이 유의미하게 다루어졌다.