경희대학교 수원캠퍼스 노천극장 주변 공원 기본계획

김동찬,이윤수,권오원,민창기,김태현,박경모 경희대학교 디자인연구원 2004 예술· 디자인학연구 Vol.7 No.1

We, Kyung-hee University in Suwon has planned to build an open-air theater behind the building of natural science, and feel the need of creating places for cultural life and recreation. As the origin aim of this construction and landscape, university students can use this facilities and place for their daily relaxation and cultivation of emotion, and they also can utilize them for places of their meetings and events. Concerning the following completion of the UN Peace Park, our theater and the surrounding places will expectingly play important roles for the park because the open-air No-cheon theater is included in the full site of the UN Peace park. The focused elements of this basic plan are maintaining the basic plan of the UN Peace Park, forming the visually creative background, of the open-air theater cultural and recreational places, balancing and integrating human, nature, and the useful facilities.

폐결핵 환자 혈청에서 수용성 Interleukin 2 수용체 및 Adenosine Deaminase 활성도에 관한 연구

고정희,박성규,백상현,박찬권,박병수,안진영,최우석,박정규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

Interleukin-2 (IL-2) induces T cell proliferation in an autocrine manner and provides a means by which antigen triggered T cells can be clonally expanded in vitro. During the following activation, the activity of IL-2 is mediated by specific high affinity IL-2 binding membrane receptors which are expressed shortly after activation. In this process, a 42 KD-fragment (soluble IL-2R) is continuously cleaved off and circulates as a soluble marker of T lymphocyte activation. Elevated level of soluble IL-2R has been identified in the serum of patients with malignant autoimmune and allergic disorders, systemic parasitic infection, undergoing graft versus host disease, acute or chronic lymphocytic leukemia and HIV-infection. ADA (adenosine deaminase) completes the process of differentiation of T cell and is essential for progression of T cell maturation. Therefore level of ADA is to correlated with magnitude of T cell immune response. The fact that expression of sIL-2R and ADA activity increases in peripheral blood T-lymphocytes of patients with active pulmonary tuberculosis suggests that T cell activation might have a major role in the pathogenesis of pulmonary tuberculosis. In order to evaluate the T cell immune response in pulmonary tuberculosis, we measured the serum concentration of sIL-2R and ADA activity in 17 patients with current pulmonary tuberculosis, 10 chronic inactive pulmonary tuberculosis, 10 as normal controls. (1) Current pulmonary tuberculosis had significantly higher levels of sIL-2R (237.24±95.47)when compared with those of inactive tuberculosis (78.6±11.06). and the control (68.17±15.4) group. (2) ADA activity in current pulmonary tuberculosis was significantly increased (34.41±20.63) when compared with those of inactive tuberculosis (24.7±14.36) and control (17.65± 5.94) group. (3) There was good correlation between sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group. (4) sIL-2R concentration and ADA activity was decreased significantly 6 months after anti-tuberculosis drug medication. In conclusion, sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group was increased when compared with those of inactive pulmonary tuberculosis and the control group. By the way, T cell mediated immune response was enhanced in current pulmonary tuberculosis, but in inactive chronic pulmonary tuberculosis who had treated by antituberculosis drug medication, the concentration of sIL-2R and ADA activity was nearly normal.

아파트 평면유형 및 가구특성에 따른 공간사용방식에 관한 연구 : 전용면적 60㎡과 85㎡ 아파트를 중심으로

박수빈,오찬옥,김석태 대한건축학회 2003 대한건축학회논문집 Vol.19 No.12

The purpose of this study was to determine the space usage behavior for the planning of apartment dwelling units. Space usage was analyzed according to household characteristics of four types apartments sized 60㎡ and 85㎡. Two hundreds ninety-eight apartment residents in Haeundae, Busan responded to the structural questionnaire, which included the space use of the living room, dining room, the master bedroom, and children's room and the satisfaction degree with the size and location of each room. The major findings were as follows: 1) The A₁type dwelling unit plans indicated a desire for the sizes of the second and the third room to be adjusted based on the number of family members. The planning of the public space varied into open or closed plan accommodated to the family life cycle. 2) The A₂ type dwelling unit plans utilized the closet helping the use of two bedrooms. The planning of the public space for the upper groups of family life cycle varied by formal entertainment in the living room and informal entertainment in dining room. 3) The B₁ type dwelling unit plans utilized the balcony and closet for the use of the second and the third room. A variety of public space organizations were suggested because of the family life cycle. 4) The B₂type dwelling unit plans utilized the balcony and closet for the use of the third room. The planning of public space varied by the different use of living room according to the family life cycle and the use of dinning room for the informal entertainment.

공공부문 정보화사업의 소프트웨어 개발비용 예측에 관한 연구

박찬규,구자환,김성희,신수정,송병선 한국경영과학회 2002 經營 科學 Vol.19 No.2

As the portion of information systems (IS) budget to the total government budget becomes greater, the cost estimation of IS development and maintenance projects is recognized as one of the most important problems to be resolved for scientific and efficient management of IS budget. Since IS budget makes much effect on the delivery time, quality and productivity of IS projects, the exact cost estimation is also necessary for the successful accomplishment of IS projects. The primary concern in the cost estimation of IS projects is software cost estimation, which requires the measurement of the size of softwares. There are two methods for sizing software : line-of-code approach, function point model. In this paper, we propose a function-point-based model for estimating software cost. The proposed model is derived by collecting about fifty domestic IT projects in public sector and analyzing their relationship between cost drivers and development effort. Since the proposed model is developed by simplifying the function point model that can be used only when detailed user requirements are specified, it can be also applied at project planning and budgeting phase.

Field Ion Microscopy를 이용한 Tungsten Silicide의 연구

박동수,정찬익,정승민 慶北大學校 自然科學大學 1985 自然科學論文集 Vol.3 No.-

The atomic structure of silicide layers grown on tungsten surface has been studied by a Field Ion Microscopy. Silicide atoms were vapor deposited on the tungsten tip by resistive heating. Tungsten tips were atomically cleaned by means of pulsed field evaporation. The silicide formation has been achieved by electrical resistive heating in the ultra high vacuum chamber. The optium temperature for tungsten silicide formation was found to be around 700 to 750℃ and its composition was WSi_2. The observed FIM images were composed of tetragonal cllb structure. The silicide grew independently on each W{001} plate, which was considered due to the W lattice constant of these planes matches well with that of the basal of the silicide.

마이크로파로 가열된 리튬 실리케이트계 무기고분자의 핵 생성 및 결정화에 관한 연구

박성수,박찬영,민성기 釜慶大學校 1999 釜慶大學校 論文集 Vol.4 No.1

A comparison of nucleation and crystallization of amorphous lithium silicate under the conventional and microwave processing was investigated. Optical microscopy(OM). X-ray diffractometry(XRD), and differential thermal analysis(DTA) were used to evaluate the results. Both conventional and microwave heat-treated samples had same nucleation temperature, 460~480℃, and same temperature of maximum nucleation rate, 580℃. From the results of DTA, the probability for the bulk crystallization increased in the microwave heat-treated samples. compared to conventional one. Degree of crystallization increased with increasing crystallization temperature in both conventional and microwave heat-treated samples. However, pattern of spherulites growth under the microwave processing appeared to be quitely different from that under the conventional one due to its internal heating.

목공예와 나무

박찬수 숲과 문화 연구회 2004 숲과 문화 Vol.13 No.5

의료기사의 누적 외상성 증후군 증상에 관한 조사

박찬호,리갑수,이성수,안규동,이병국 순천향대학교 산업의학연구소 2001 순천향산업의학 Vol.7 No.1

The cumulative trauma disorder is a disease group of musculoskeletal systems developed by repeated work, which became greate concern in occupational health problem in Korea recently. Many paramedicals working in the department of Laboratory, Radiology, and Rehabilitation of the hospital have been engaged in the simple repetitive hard works causing cumulative trauma disorder. This is the study on the cumulative trauma disorder in those medical technicians. Total 285 (180 male, 105 female) medical technicians and office workers working in the hospital were surveyed with the self-administered questionnaires. They included the questions such as age, sex, marital status, education, height, weight, smoking and drinking history as a general characteristics and work department, kind of work, work duration, work conditions as a work characteristics. And also subjective symptoms related with the work in each region of body area were questioned. Among the work conditions, there were significant differences between medical technicians and office workers (e.g., high in medical technicians) in daily works lifting patients or heavy equipments, works moving continuously and rapidly, works with uncomfortable position, works keeping neck and upper arms in uneasy position. Complained rate of subjective symptoms was significantly higher in physical therapist and in the group of work duration over 10 years. The significant symptoms were pain, abnormal sensation, burning sensation. The significant factors affecting the subjective symptoms were female and work duration over 10 years for wrist area, female and current smoking for knee or ankle area, physical therapist, work duration between 6 and 9 years for lumbar area, female and radiologic technicians and work duration over 6 years for shoulder area. None was significant for neck area.

藥鍼用蜂毒液이 黑色腫細胞에 미치는 抗癌效果에 對한 分子生物學的 硏究

朴贊烈,南相水,金昌煥,李栽東,姜成吉,李潤浩,安秉哲 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

To study anti-cancer effect and molecular biological mechanism of bee venom for aqua-acupuncture, the effects of bee venom on cell viability, apoptosis, and cell cycle were analyzed using MTT assay, tryphan blue assay, [3H]thymidnine release assay, flow cytometric analysis, activity of caspase-3 protease activity assay, and immunocytometric analysis of PCNA. To explore whether anti-cancer effects of bee venom are associated with the transcriptional control of gene expression, quantitative RT-PCR analysis of apoptosis- and cell cycle-related genes was performed. The obtained results are summarized as follows: 1.The MTT assay demonstrated that cell viability was decreased by bee venom in a dose-dependant manner. 2.Significant induction of apoptosis was identified using tryphan blue assay. [³H]thymidine release assay, and flow cytometric analysis of sub G₁fraction. 3.In analysis of caspase-3 protease activity, the activity had increased significantly, in a dose-dependant manner. 4.Quantitative RT-PCR analysis of the apoptosis-related genes showed that Bcl-2 and Bcl-X□ were down-regulated whereas Bax was up-regulated by bee venom treatment. 5.In flow cytometric analysis of cell cycle and immunocytometric analysis of PCNA expression, cell numbers of G₁phase was increased by a dose-dependant manner. 6.In quantitative RT-PCR analysis of the cell cycle-related genes, p21, p27, and p57 were increased, while Cyclin D1, CDK4, c-Myc, c-Fos, and Histone H3 were decreased. In contrast, there were no remarkable changes in expression levels of CDC2 and c-Jun.

조기 류마티스 관절염의 약물치료

박민찬,이수곤 대한의사협회 2003 대한의사협회지 Vol.46 No.11