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Naveen D. Daniel,Sangmook Lee,Lalitha Naveen 한국재무학회 2016 한국재무학회 학술대회 Vol.2016 No.05
Prior literature has documented that analysts engage in valuable information discovery and information interpretation. Our contribution is to introduce and document a third role that analysts play that is also valuable to investors, which we term “stock timing.” Specifically, we define a timing report as one where the analyst revises his recommendation but does not revise the Price Target or any of the 23 fundamental drivers of stock price (such as EPS, FCF) tracked by I/B/E/S. Because the analyst maintains the same price target as in his prior report but still revises his recommendation, such timing calls are contrarian valuation calls. Analysts issue timing downgrades (upgrades) in response to price increases (declines) since the release of their prior report on the firm. About 30% of all revisions are timing reports, indicating the importance of the timing role played by analysts. We find the return over a 3-day window around the report date is over 2% in magnitude. Further, 62% of the reports are winners (have announcement returns that have the correct sign), 10% of the reports are large enough to be considered influential, and 37% of the reports are persistent winners. These results suggest that analysts have timing ability. We find considerable cross-sectional and time-series variation in timing ability. We find that the probability of issuing a timing report is positively related to the opportunities to time the stock provided by potential mispricing. Conditional on issuing a timing report, the probability of issuing a winner, an influential winner, or a persistent winner is positively related to analyst experience and negatively related to the costs associated with issuing a timing report.
Intelligent Control of Space Robot System using RBF Neural Network
Naveen Kumar,Vikas Panwar 제어로봇시스템학회 2015 제어로봇시스템학회 국제학술대회 논문집 Vol.2015 No.10
In this paper, an intelligent controller is proposed for a space robot system with an attitude controlled base without joint acceleration measurements. The controller consists of computed torque type part, RBF neural network and an adaptive controller. The controller achieves the required tracking effectively. The controller is able to learn the existing structured and unstructured uncertainties in the system in online manner. The RBF network learns the unknown part of the space robot system dynamics with no requirement of the offline training. The adaptive controller is used to estimate the unknown bounds on unstructured uncertainties and neural network reconstruction error. The overall system is proved to be asymptotically stable in the sense of Lyapunov. Finally numerical simulation studies are performed to evaluate the controller performance.
Naveen Sharma,심윤범,박수현,임수민,김성수,정준섭,홍재승,서홍원 대한약리학회 2015 The Korean Journal of Physiology & Pharmacology Vol.19 No.3
Sulfonylureas are widely used as an antidiabetic drug. In the present study, the effects of sulfonylurea administered supraspinally on immobilization stress-induced blood glucose level were studied in ICR mice. Mice were once enforced into immobilization stress for 30 min and returned to the cage. The blood glucose level was measured 30, 60, and 120 min after immobilization stress initiation. We found that intracerebroventricular (i.c.v.) injection with 30 μg of glyburide, glipizide, glimepiride or tolazamide attenuated the increased blood glucose level induced by immobilization stress. Immobilization stress causes an elevation of the blood corticosterone and insulin levels. Sulfonylureas pretreated i.c.v. caused a further elevation of the blood corticosterone level when mice were forced into the stress. In addition, sulfonylureas pretreated i.c.v. alone caused an elevation of the plasma insulin level. Furthermore, immobilization stress-induced insulin level was reduced by i.c.v. pretreated sulfonylureas. Our results suggest that lowering effect of sulfonylureas administered supraspinally against immobilization stress-induced increase of the blood glucose level appears to be primarily mediated via elevation of the plasma insulin level.
Naveen Sharma,심윤범,박수현,김성수,이재령,정준섭,서홍원 한국통합생물학회 2015 Animal cells and systems Vol.19 No.6
Effects of histamine receptors agonists or antagonists administered centrally (supraspinally or spinally) on immobilization stress-induced blood glucose levels were studied in Institute for Cancer Research mice. Mice were pretreated intracerebroventricularly (i.c.v.) or intrathecally (i.t.) with histamine (H1, H2, H3 and H4) receptor agonists or antagonists 10 min prior to immobilization stress (IMO) stimulation for 30 min. We found that the increased blood glucose level induced by IMO was attenuated by the i.c.v. pretreatment with α-methylhistamine (H3 agonist). However, H3 antagonist, H1, H2 and H4 receptor agonists and antagonists did not affect the blood glucose level. Also, i.t. pretreatment with α- methylhistamine or VUF 8430 attenuated the increased blood glucose level induced by IMO. In addition, cetirizine and carcinine enhanced the increased blood glucose level induced by IMO. However, the blood glucose level was not affected by H1 and H2 receptor agonists, H2 and H4 receptor antagonists. Corticosterone and insulin levels were also measured in α-methylhistamine (i.c.v or i.t) and with VUF 8430, carcinine and cetirizine (i.t.) treated group. We found that the corticosterone level was increased only by i.t treatment with α-methylhistamine, whereas the insulin level was attenuated by i.c.v or i.t. treatment with α-methylhistamine and i.t treatment with VUF 8430, carcinine and cetirizine. Our results suggest the active involvement of histamine receptor in blood glucose regulation in IMO.
Naveen Kumar Mekala,Rama Raju Baadhe,Sreenivasa Rao Parcha 한국조직공학과 재생의학회 2013 조직공학과 재생의학 Vol.10 No.4
Mesenchymal stem cells (MSCs) isolated from umbilical card blood were capable of differentiated in to multiple mesenchymal cell lineages. The objective of the current study was to establish a reproducible system for the in vitro osteogenic differentiation of human MSCs, and to characterize the effect of changes in the microenvironment upon differentiation. In our previous studies, MSCs cultured in varying concentrations of L-ascorbic acid (50µM to 500µM) had shown the various levels of osteoblast differentiation, as determined by morphology, alkaline phosphatase activity, modulations in osteocalcin mRNA expression, and mineralized extracellular matrix (ECM) deposition holding inorganic hydroxyapatite (HA) and Tricalcium phosphate (TCP). In present study, we noticed a study increase in APase activity up to 250µM L-ascorbic acid and by end of 16 days, cells gained cuboidal morphology, which is characteristic feature of osteoblasts. The intense sharp difractograms (peaks) between 30o-35o demonstrate the deposition of HA and TCP, which are major inorganic components of bone. The reproducible results of our studies provided a useful model for evaluating the factors responsible for the stepwise progression of cells from undifferentiated precursors to secretary osteoblasts, and eventually terminally differentiated osteocytes.
실세계 조명 정보를 포함하는 HDR영상 기반 소수 광원 추정 기법에 관한 연구
Naveen Dachuri,유재덕(Jae-Doug Yoo),김승만(Seung-man Kim),이관행(Kwan H. Lee) 한국정보과학회 2005 한국정보과학회 학술발표논문집 Vol.32 No.2
본 논문에서는 실세계 조명 정보를 표현하는 HDR(High Dynamic Range) 영상으로부터 소수의 방향성 광원을 추정하는 기법을 제안한다. 광원 추정을 위해 노출 시간을 달리한 일련의 일반 영상으로부터 실세계의 조명 정보를 선형적으로 표현할 수 있는 HDR영상을 생성한다. HDR영상의 색상 및 명도 변화를 이용하며 영역을 분할하고, 분할된 영역으로부터 명도 평균과 가중치를 이용하여 방향성 광원의 파라미터를 추출하는 방법을 제안한다. 제안된 방법의 장점은 비반복적인 기법을 사용하여 일관된 결과를 산출하며 사용자의 입력없이 자동으로 계산하는 것이다. 추정된 광원은 그래픽 하드웨어를 사용한 실시간 렌더링에 적용 가능하다. 또한 실시간 렌더링이 중요한 가상현실이나 증강현실 분야에서 가상의 오브젝트를 렌더링할 때 IBL(Image Based Lighting)등의 전역조명 효과와 유사한 사실적인 영상을 얻을 수 있다.
Chiral Cyclodimeric Zinc(II) Complexes: Enantio-recognition via Differential Pulse Voltammetry
Naveen, Kanagaraj,Lee, Haeri,Lee, Daseul,Lee, Jeong Jun,Moon, Jong-Min,Shim, Yoon-Bo,Jung, Ok-Sang The American Chemical Society 2018 CRYSTAL GROWTH AND DESIGN Vol.18 No.10
<P>Self-assembly of a series of ZnX<SUB>2</SUB> (X<SUP>-</SUP> = Cl<SUP>-</SUP>, Br<SUP>-</SUP>, and I<SUP>-</SUP>) with (<I>S</I>)-(1-isonicotinoylpyrrolidin-2-yl)methyl isonicotinate (L) as a new chiral hemicircular bidentate ligand yields a system comprising 30-membered metallacyclodimeric species [ZnX<SUB>2</SUB>L]<SUB>2</SUB> with two chiral centers. In the solid state, the metallacyclodimers’ packing arrays differ according to the anions and nestled solvate molecules. In the present study, the differential pulse voltammetry (DPV) technique was employed for chiral discrimination of amino acid enantiomers with <I>S</I>-chiral [ZnX<SUB>2</SUB>L]<SUB>2</SUB> and was found to be an effective tool for enantio-recognition of amino acids.</P><P>Chiral cyclodimeric species [ZnX<SUB>2</SUB>L]<SUB>2</SUB> (X<SUP>−</SUP> = Cl<SUP>−</SUP>, Br<SUP>−</SUP>, and I<SUP>−</SUP>) have showed significant enantioselective chiral recognition for amino acids via differential pulse voltammetry (DPV). <I>S</I>-Chiral zinc(II) cyclodimers provide more effective enantio-recognition with the <SMALL>D</SMALL>-form than with the <SMALL>L</SMALL>-form amino acids. Halogen effects bound to zinc(II) ion on the chiral recognition data have been investigated.</P> [FIG OMISSION]</BR>