난소암의 조기진단

남주현,목정은 울산대학교 의과대학 1993 울산의대학술지 Vol.2 No.2

Ovarian cancer is the leading cause of death from gynecologic malignancies. In 1992, it has been reported that the incidence of ovarian cancer was 3% of all female malignancies in Korea. During the last decade, the incidence of cervical cancer which is the most common one of female malignancies was gradually declining, however that of ovarian cancer tended to be slightly increasing probably because of changes in socioeconomic status of this country. Despite of aggressive debulking operation and intensive platinum-based combination chemotherapy, the overall survival rate for ovarian cancer has not changed appreciably over the last twenty years. One of the reasons for poor prognosis of ovarian cancer is that greater than 70% of patients with ovarian cancer is unfortunately detected after the disease has already spreaded beyond the pelvis because of the lack of early symptoms. The cure rate for these patients with advanced ovarian cancer is only 15-20%, This low survival rate is in marked contrast to that of as high as 90% with stage I disease. Therefore, development of early detection method for ovarian cancer would be the best way to reduce the mortality rate of this disease. Ultrasonography and serum tumor marker, CA 125 have been extensively studied for early detection of ovarian cancer. Recently, combined use of transvaginal color Doppler technique is studied to increase the specificity of the screening test. However, the value of these methods as a screening test is still debating. So far, unfortunately there is no conclusive method which has cost-effectiveness and perfect sensitivity and specificity for ovarian cancer screening. Moreover, the optimal population and interval for ovarian cancer screening are not currently defined. In this review, recent data of studies using ultrasound and serum marker, CA 125 and debating issues for ovarian cancer screening are discussed.

중학교 가정과 교수-학습 방법의 개선을 위한 집단탐구 수업모형의 적용연구

남현주,유태명 한국 가정과 교육 학회 1996 한국가정과교육학회지 Vol.8 No.2

This study was to develop and to suggest a lesson plan for the area of 'Human Development and Family Relationship' in home economics for junior high school, based on Thelen's'Group Investigation Model', Group investigation model by Thelen was developed from the theory that the education with special purpose such as societic knowledge is a method to lesson one's conflict. This study further developed from three main concepts : inquiry, knowledge and activities of learning group. This model can be used for any age and any subjects in order to solve the arised problems, rather than to accept pre-organized and pre-decided information. This study is organized around activities for seeking and practicing the rages of action to create dispersal home. First, one unit 'Understanding of Family' was chosen that concerns and suitable for group investigation model Second, From the chosen chapter and problem were analyzed organized. Third, the chosen problem were re-analyzed, then a model lesson for group investigation was proposed.

국민 여가활동기회의 효율적인 분배와 생산유인 효과 확대를 위한 스포츠시설 및 스포츠 관련 산업의 관광자원화 방안을 위한 연구

남덕현,김천중,이주형 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.1

The purpose of this study is to examine the recognition and satisfaction of sport tourism as an area of tourism industry, and show the actual status of sport tourism, suggest the strategies to develop sport tourism goods according to sports tourism resources. This study is based on the survey of residents, physical education teachers, tour industry managers and local government employees, who were asked about what impact sports tourism had on local societies and environments. The data obtained from the returned questionnaire were coded and transcribed for a statistical analysis. collected data were analyzed though SPSS 10.0using such statical methods as a descriptive statistical analysis, chi square test, ANOVA test. With the twenty first century upcoming, sport tourism is recognized as a necessity of life for every person in the world. In addition, the rapid changes of social phenamenons such as the changing of a basic sense of value and life style. the improvement of income, the development of traffic systems, communication facilties, and medias, have a great influence on the desire for sport tourism. Compared with the past tourism that were mostly passive and superficial sight seeing tour, sport tourism is an active and exhilarating tour, therefore sport tourism could provide tourist with satisfaction of needs. Sports tourism is sure to become one of major industries. This study was done with the limited data, so the result does not fully represent the comprehensive impact of sport tourism and strategies of sport tourism resources.

흡연 및 비흡연 정신분열증 환자간의 인지 기능과 치료 반응의 차이

남궁기,민성길,이희상,조현상,김세주 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.4

연구 배경 : 본 연구는 정신분열증 환자에서 흡연 여부에 따라 정신분열증 환자군의 정신과적 과거력 및 현재 증상, 치료 반응과 인지 기능 등에 어떤 차이가 있는 지를 알아보려는 것이다. 연구 방법 : 정신분열증 환자 중 36명의 흡연군과 31명의 비흡연군을 연구 대상으로 하였다. 현재의 증상을 평가하기 위해서 양성 및 음성 증상 척도(Positive & Negative Syndrome Scale) 및 전반적 기능 평가 척도(Global Assessment Scale)를 상용하였고, 추체외로계 부작용을 추체외로계 부장용 평가척도(Rating Scale for Extrapyramidal Side Effects)로 측정하였다. 흡연군과 비흡연군의 인지 기능을 평가하기 위해 비엔나 검사 중 SPM(Standard Progressive Matrices), Cognitron 및 FFA(Flicker Fusion Analyzer) 검사를 실시하였다. 연구 결과 : 1) 흡연군과 비흡연군에 비해 유병 기간이 유의하게 길었음에도 불구하고, 입원 시의 증상 정도(PANSS 총점)가 유의하게 낮았고, 기능 정도(GAS 점수) 역시 유의하게 높았다. 2) 정신분열증의 치료 반응에 영향을 미칠 것으로 생각되는 나이와 유병 기간을 통제한 상태에서 흡연여부에 따른 치료 반응의 차이를 검증해 본 결과, 흡연 여부에 따른 일일 약물 사용량, 추체외로계 부작용 및 증상 호전율(PANSS 호전율)이나 기능 호전율(GAS 호전율)에 유의한 차이는 없었다. 또한 인지 기능에 영향을 미칠 것으로 생각되는 나이, 유병 기간, 항전신병약물 용량 및 증상의 정도를 통제한 상태에서 흡연 여부에 따른 인지 기능의 차이를 검증해 본 결과, 흡연 여부에 따른 SPM 값, COG-R 및 FFA 갑의 차이는 없었다. 3) 흡연군 내에서 흡연 정도와 치료 반응 및 인지 검사 점수와의 관계를 알아보기 위해, 나이와 유병 기간 요인을 통제한 상태에서 일일 평균 흡연량과 여러 임상 척도와의 상관 관계를 분석해 보았다. 그 결과 일일 흡연량과 증상 호전율(PANSS 호전율) 이나 기능 호전율(GAG 호전율) 사이에 통계적으로 유의한 상관 관계를 보였다. 그러나 총 흡연 기간은 치료 반응 및 인지 기능과는 통계적으로 유의한 상관 관계를 보이지 않았다. 결 론 : 이상의 결과를 종합해 보면 흡연 정신분열증군은 비흡연 정신분열증군에 비해 입원 시 증상이 경미하고 기능이 좋으며, 흡연 정신분열증군에서는 흡연량이 많을수록 치료 시 증상 및 기능이 호전율이 높다고 할 수 있다. 그러나 흡연군에서 일일 약물 사용량이 높다거나, 추체외로계 부작용이 덜 나타난다거나 지능 저하가 덜하다는 이전의 연구 결과들은 입증되지 않았다. Objectives : The purpose of this study was to examine the differences of past histories, current symptoms, treatment responses and cognitive and functions between smoking and nonsmoking schizophrenic patients. Methods : The subjects were composed of 67 schizophrenic patients including 36 smokers and 31 non-smokers. They were examined by psychiatric history checklist, Simpson and Angus's rating scale for extrapyramidal side effects, positive & negative syndromes scale(PANSS), global assessment scale(GAS), and Vienna test including Standard Progressive Matrices(SPM), Cognitron, and Flicker Fusion Analyzer(FFA). Results : The results were as follows : 1) Although the duration of illness of smokers was longer than that of non-smokers, the smokers had significantly higher score of GAS and significantly lower score of PANSS than non-smokers at admission. 2) With effects of age and duration of illness controlled, there were no differences of mean dosage of neuroleptics, extrapyramidal side effects, PANSS improvement rate and GAS improvement rate between both groups. 3) With effect of age, duration of illness, and total PANSS score controlled, there were no differences of score of SPM, cognitron, and FFA. 4) In smokers, the PANSS improvement rate and the GAS improvement rate were positively correlated with mean number of daily smoked cigarettes, with effects of age and duration of illness controlled. Conclusions : In schizophrenic patients, smokers had less severe symptoms than non-smokers. In smokers, the PANSS improvement rate and the GAS improvement rate were positively correlated with mean number of daily smoked cigarettes. But Smokers were not proven to have received higher dosage of neuroleptics, to have lower extrapyramidal side effects, or to have less severe impairment of cognitive function.

사람과 쥐에서 식이내 n6 와 n3 불포화지방산이 혈장 지질조성에 미치는 영향

박현서,남정혜,최주선 慶熙大學校 1991 論文集 Vol.20 No.-

To compare the plasma lipid-lowering effect of dietary n6 and n3 polyunsaturated fatty acids(PUFA) in human and rats, ten college women were divided into 5 groups and treated for 5 weeks with 1 week interval between treatments and subjects serving as their own controls. Male Sprague Dawley rats were divided into 3 groups and fed the experimental diets for 6 weeks. The experimental diets were corn oil diet for n6 linoleic acid, perilla oil diet for n3 α-linolenic acid and fish oil diet for n3 eicosapentaenoic acid (EPA) and docosahexaenoic acid(DHA). Dietary fat was supplied at 30% Cal and modified to give the total amount of satu-rated fatty acid(SFA) and monoenoic acid(MEA)at constant level. In human, there was no significant effect on plasma cholesterol (Chol)level by different PUFA. However, on a gram­for­gram basis, there was a trend that the decrease in plasma Chol was proportionate to the degree of fat unsaturation. HDL―Chol content was significantly increased only in fish oil diet but no change in the relative proportion of its chemical components of HDL. In rat, plasma Chol and HDL―Chol levels were significantly lowered by fish oil than corn oil and perilla oil. Plasma Chol―lowering effect in human and rats was greater by n3 EPA and DHA than n6 linoleic acid. Plasma triglyceride(TG)level in human was significantly lowered only in fish oil diet but no significant effect on the relative proportion of TG in VLDL. Plasma TG in rats was significantly decreased by both perilla oil and fish oil than by corn oil. Therefore, plasma TG―lowering effect was in the order of n3 EPA+DHA>n3 α­linolenic acid >n6 linoleic acid. In conclusion, perilla oil and fish oil which contain n3 series PUFA may have important nutritional benefit in the prevention and treatment of atherosclerotic disease.

내담아동 어머니의 성인애착, 부모-자녀관계 및 사회적 지지가 부모상담의 작업동맹에 미치는 영향

이주현, 남종호 가톨릭대학교 사회과학연구소 2012 社會科學硏究 Vol.28 No.-

서울시내 치과의원의 소독기 실태

권주현,김성태,김광만,김경남 대한치과기재학회 1997 대한치과재료학회지 Vol.24 No.2

Sterilizer is one of the necessary equipments in dental clinics for aseptic treatment. There are many types of sterilizer, such as autoclave, chemiclave, dry heat sterilizer, UV(Ultra Violet) sterilizer, boiling sterilizer, EO(Ethylene Oxide) gas sterilizer, by sterilizing mechanis. To evaluate the type and sterilizing ability, one surveyer visited 100 dental clinics in Seoul and surveyed some items, such as age and gender of dentist, type, location and using period of sterilizer, how many sterilizing time per day and who operate sterilizer, so on. As preacticall operation the sterilizer, sterilized basillus subtilis in test tube and incubated it. Then it's turbidity was observed. The results were as follows 1. The descending order of plenty were autoclave(68), UV sterilizer(26), chemiclave(12), dry heat sterilizer(4) and boiling sterilizer(2). 2. The descending order of sterilizing ability were dry heat sterilizer(100%), autoclave(89%), chemicloave(73%), UV sterilizer(43%) and boiling sterilizer(0%). 3. Sterilizing ability in dental clinics that have both sterilizer, autoclave and UV sterilizer, chemiclave and UV sterlilzer was low than single sterilizer(autoclave, chemiclave). 4. The descending order of location of sterilizer were treatment room, laboratory room, sterilizing room and the order of operator were assistant, hygiene and both assistant and hygiene.

역기능 완벽주의 : 인지세트, 대처방식 및 심리적 부적응과의 관계 Relation to cognitive set, coping and psychological maladjustment

임주현,정남운 가톨릭대학교 사회과학연구소 2003 社會科學硏究 Vol.19 No.-

본 연구는 역기능 완벽주의와 심리적 부적응 사이의 매개변인들의 효과를 경로분석을 통하여 모델 검증하였다. 여기서 매개변인은 사회적 지지 지각과 자기지각으로 이루어진 인지세트와 대처방식으로, Lazarus와 Folkman(1984)이 제안한 적응에 대한 스트레스와 대처 모델(stress and coping model of adjustment)에 근거하여 설정되었다. 기본 경로모델 중 부합도가 충분하지 않은 모형을 단계적으로 수정하여 최종모델을 채택하는 과정을 거쳤다. 그 결과 각각의 수정된 경로모델에서 사회적 지지 지각과 대처방식은 매개변인의 효과를 나타냈으나, 자기 지각은 사회지지 지각과만 유의미한 관계를 나타냈고 매개효과는 나타내지 않았다. 역기능 완벽주의와 우울 모델, 역기능 완벽주의와 불안 모델에서는 한 가지 직접경로와 두 가지 간접경로를 볼 수 있었고, 역기능 완벽주의와 강박 모델에서는 직접경로와 간접경로가 각각 한 가지씩 나타났다. 마지막으로 본 연구가 지니는 의의와 제한점, 그리고 추후 연구를 위한 제안 사항들을 기술하였다. This study was to investigate the effect of mediation variables between perfectionism and psychological maladjustments by verifing path model. Mediation variables are cognitive set including social support perception, self perception and coping strategy based on the Stress and Coping Model of Adjustment by Lazarus and Folkman(1984). The final model was modified repeatedly when fit indexes of base path model were not enough to explain data. The result showed that modification path models were selected about depression, anxiety, obsession-compulsion. As a result, social support perception and coping strategy had an effect on mediation variable. Self perception was related with only social support perception and didn't have an effect on mediation variables. Specifically first, There were one direct path and two indirect paths between perfectionism and depression of psychological maladjustments. Second, There were one direct path and two indirect paths like depression model between perfectionism and anxiety of psychological maladjustments. Third, There were one direct path and indirect path. At the end of this, implications, the limitations of this study and suggestions for future were discussed.

장시간 불가피한 공복(fasting)후 인체의 내분비 변화 : 삼풍백화점 붕괴 사고후 구조된 3인의 증례 THREE CASES IN COLLAPSE OF SAMPOONG DEPARTMENT STORE

박규남,황주일,박조현,오동렬,이원재,오승택,김세경,김인철 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

The interactions between nutrition and the endocrine system are more intimate and complex that previously thought. Nutrition modulates secretion and activity of many hormones, as part of the stress adaptation process. Fasting, in particular, produces a number of important changes in the endocrine system, with teleological purpose of helping the body tolerate the lack of food ingestion. These changes are therefore beneficial and protective, although at times they may not appear to be that way. The endocrine changes of fasting mediate the metabolic response. We must emphasize that these changes are completely reversible when appropriate nutrition is established. These changes are as followes: 1) decreased insulin and increased glucagon levels, 2) decreased thyroid effect, 3) decreased sympathetic activity, 4) hypothalamic hypogonadism, 5) decreased growth, 6) altered glucocorticoid secretion and metabolism, 7) impaired mineralocorticoid response, 8) decreased ADH secretion and effect. We experienced three cases of involuntary prolonged fasting after collapse of Sampoong department store. They were released from collapsed field after 11(case Ⅰ), 13(case Ⅱ), 17days(case Ⅲ) respectively. In each case, the endocrine changes of plasma levels were as followes: decrease of cortisol in case Ⅰ, increase of GH in case Ⅱ, decrease of free T3, T3, cortisol and increase of reverse T3, insulin in case Ⅲ. Each one did not show the same endocrine changes of plasma levels. But we think these changes of fasting are beneficial in metabolic response of human.

준설토의 건조수축에 의한 강도증가 특성과 지지력에 관한 연구

유남재,이종호,이명욱,김현주 강원대학교 산업기술연구소 2000 産業技術硏究 Vol.20 No.A

This research is results of experimental and numerical works on characteristic of strength increase and bearing capacity in dredged and reclaimed soil due to desiccation shrinkage. For a soil sampled from southern coastal area in Korea, basic soil property tests and standard consolidation test with falling head permeability tests were carried out to obtain consolidational characteristics of soil. Double cone penetration test. laboratory vane test and unconfined compression test were also performed to investigate the change of shear strength with degree of desiccation. Model tests were performed in 1G environment and 30G level artificially accelerated condition by using the centrifuge model test facilities to investigate the bearing capacity of desiccated ground. Test results were analyzed by using the bearing capacity of desiccated ground. Test results were analyzed by using the theoretical and load-settlement characteristics method proposed by Meyehof & Hanna(1978). On the other hands, the numerical technique, using the finite strain consolidation theory considering the effect of desiccation was used to estimate the appropriate time of using heavy construction equipments in field with respect to strength increase due to desiccation.