A meta-analysis of adolescent psychosocial smoking prevention programs in the United States: Identifying factors associated with program effectiveness

Hwang, Myung-Hee-Song Korean Society for Health Education and Promotion 2007 보건교육건강증진학회지 Vol.24 No.5

청소년을 위한 학교 흡연예방 프로그램은 사회심리 이론에 근거한 프로그램이 대체로 성공적이었다고 알려져 있으나, 각 프로그램의 효과 정도에는 많은 차이가 있다. 이 연구는 다른 메타 분석처럼 전체적인 프로그램 효과도를 측정하여 일반적인 결론을 유도한 것이 아니라, 프로그램의 효과와 관계가 깊은 요인 (Explanatory Variables)을 자세히 파악하여 보건교육 담당자, 연구원, 또는 정책 결정자들에게 구체적인 가이드라인을 제공하는 데에 목적을 두고 있다. 주요한 연구결과는 다음과 같다. 1. 8-12학년 학생들보다는 초등학교에서 중등학교로 바뀌는 5-7학년 학생들에게 흡연예방 프로그램은 더 효과가 있었다. 2. 연구 방법론에 있어서는 experimental design, random assignment, 순수 비교그룹을 사용하였을 경우, implementation fidelity와 instrument reliability가 높은 경우, 또는 10% 미만의 attrition rates일 때 프로그램 효과도 (effect size)가 더 높게 나타났다. 3. 프로그램 실행 시 또래 리더를 사용하였을 경우, 알코올 등 다른 약물을 배제한 담배만을 중점적으로 다루었을 경우, 적어도 10회 이상 연속적으로 이루어지거나 프로그램 종료 후 일년 뒤에 추가 프로그램이 주어진 경우가 더욱 효과적이었다. Adolescent psychosocial smoking prevention programs have been successful, but limited in the magnitude of program effects. The present study is the secondary analysis after the previous study estimated mean effect sizes in smoking knowledge, attitudes, skills, and behaviors with treatment variables. Regardless of overall program effect estimations that other meta.analysis studies have done, this study is conducted to identify explanatory variables that are likely to increase program effects. A decrease of adolescent smoking behaviors is associated with the following factors: a. Younger students ($5^{th}-7^{th}$) than older students ($8^{th}-12^{th}$). b. Research methodology using true experimental design, quasi experimental design with equivalence between groups, use of random assignment, 10% or less attrition rate, use of a no treatment control group, high implementation fidelity, and/or acceptable instrumentation reliability. c. Programs using trained peer leaders, targeting cigarette smoking only, implementing 10 or more treatment sessions and/ or providing booster sessions.

제5주제 : 미국 California 주의 건강증진사업 사례

Myung-hee Song Hwang 한국보건교육건강증진학회 2005 한국보건교육·건강증진학회 학술대회 발표논문집 Vol.- No.-

미국 캘리포니아 주의 건강문재로는 흡연, HIV/AIDS, 천식, 정신질환, 아동비만, 유방암, API, 건강한 생활양식 형성, 인종간의 건강격차 등을 들 수 있다. 이러한 건강문제를 해결하기 위해 캘리포니아주에서 진행되는 지역사회 중재전략은 지역사회 단체와의 협력이라는 특성을 지니고 있으며, 도시지역의 노인이나 다양한 인종들을 대상으로 하는 프로그램들의 경우는 교회를 통한 접근방법이 빈번하게 활용된다. 중재 프로그램들은 지역사회 조직모형과 역량강화의 개념을 활용하며, 문화적으로 다른 배경을 가진 인구집단을 대상으로는 이들의 요구에 맞는 프로그램을 진행하는 형태로 기존의 프로그램을 채택하는 것이 아닌 이들의 다양한 요구에 맞도록 수정된 프로그램을 제공하고 있다. 개인 간 의사소통을 활용하여 사회적 관계망의 활성화를 도모하며, 일반인이 건강지도자가 되는 교육모형도 활용하고 있다. 한국교민사회 자문위원회(Korean Community Advisory Board, KCAB)는 CDC PRC(CFCH)의 기금으로 진행되는 연구 프로젝트를 수행할 목적으로 1993년 설립되었다. 장기적인 지역사회 건강증진을 위하여 전문가와 일반인 지도자들이 지역사회에서 협력하는 방법을 활용하며 요구도 진단, 수행 평가, 건강옹호와 같은 다양한 사업을 진행한다. 회원들은 핵심 회원과 일반회원으로 구분되고 이들은 사업의 수행과 관련된 의사결정에 도움을 주게 된다. 한국교민사회 자문위원회가 수행한 프로그램은 "Health is Strength", "Virtual Village Program"이 있으며, 현재는 "Quitting is Winning"이라는 미국거주 한국 남성을 대상으로 하는 인터넷 금연 프로그램을 수행하고 있다. 또한 캘리포니아 주 거주 한국인의 건강상태에 대한 조사를 진행하고 그 결과를 보고하는 프로젝트를 진행하고 있다. 이들이 하는 주요 업무는 지역에서 발생되는 건강문제에 대한 우선순위를 파악할 수 있도록 하여 한국교민들의 건강요구를 파악하고 사업의 우선순위를 설정하는데 도움을 주고 있다. 센터에서 진행되는 한국교민 대상 연구나 사업에 가장 효과적일 수 있는 방법에 대한 지침이나 정보를 제공한다. 또한 문화적으로 민감한 사항이나 적절성 여부에 대한 확인을 하며 연구결과를 보고하고 확산하는데 도움을 주고 있다. 캘리포니아 주는 다양한 인종들이 거주하는 지역이다. 따라서 문화적 민감성이나 문화적 대응전략, 문화적 적절성은 건강증진사업을 수행할 경우에 매우 중요한 이슈가 된다. 또한 이들은 소수민족인 경우가 많아 언어장벽으로 인하여 의료서비스 이용에 제한을 받게 된다. 따라서 보건의료전문가들은 이러한 문화적 요소들을 능숙하게 다루는 기술이 필요한데, 이러한 기술이란 문화가 다른 사람들 간에는 갈등이 존재한다는 점을 인식하고, 건강관련 믿음과 건강행동에 영향을 미치는 사회문화적 요인들을 파악하고, 대안적 해결책을 재시하며, 결과를 평가할 수 있는 능력을 의미한다. 이러한 영역에서 health care interpreter는 소수인종의 보건의료 서비스의 원활한 이용을 위하여 매우 활발한 역할을 수행하고 있다.

A large-scale screening analysis for the evaluation of Bakanae disease in rice

Myung-Hee Kim,Saet-Byeol Lee,Tackmin Kwon,Un-Ha Hwang,Soo-Kwon Park,Yeong-Nam Youn,Jong-Hee Lee,Jun-Hyun Cho,Dongjin Shin,Sang-Ik Han,Un-Sang Yeo,You-Chun Song,Min-Hee Nam,Dong-Soo Park 한국육종학회 2013 한국육종학회 심포지엄 Vol.2013 No.07

Bakanae disease of rice, caused by Fusarium moniliforme Sheldon, the imperfect stage of Gibberella fujikuroi, is one of the most important rice diseases worldwide, but no rice variety has been found to be completely resistant to this fungus. Cultivation of resistant cultivars is the most beneficial way of reducing quantitative or qualitative losses to for bakanae disease in rice. To facilitate the study of this disease, accurate and large scale screening methods were developed for the inoculation and evaluation of Bakanae disease. Even and large scale infection was achieved by using F. moniliforme spore in tissue embedding cassette and seedling tray. The efficiency of F. moniliforme infection with the concentration of 1×106 spore/ml caused better distribution (F-value=33.96) than 1×102 (F-value=10.69), and 1×104 spore/ml (F-value=2.63). We established new criteria of healthy and non-healthy plant, and introduced calculation of proportion of healthy plants to meet fast evaluation of resistance level of each variety. The effect of F. moniliforme strains containing different genetic background was also evaluated with rice varieties to figure out the stability of resistance level. GA3 response of rice variety was significantly correlated with bakanae disease, but it did not adequate for direct indicator of bakanae disease resistance. These results indicated that a large scale infection method developed in this study is fast and reproducible, as well as a disease evaluation system provides an accurate measurement of bakanae disease resistance of rice.

Structural insights into the regulation of sialic acid catabolism by the <i>Vibrio vulnificus</i> transcriptional repressor NanR

Hwang, Jungwon,Kim, Byoung Sik,Jang, Song Yee,Lim, Jong Gyu,You, Dong-Ju,Jung, Hyun Suk,Oh, Tae-Kwang,Lee, Jie-Oh,Choi, Sang Ho,Kim, Myung Hee National Academy of Sciences 2013 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.110 No.30

<P>Pathogenic and commensal bacteria that experience limited nutrient availability in their host have evolved sophisticated systems to catabolize the mucin sugar N-acetylneuraminic acid, thereby facilitating their survival and colonization. The correct function of the associated catabolic machinery is particularly crucial for the pathogenesis of enteropathogenic bacteria during infection, although the molecular mechanisms involved with the regulation of the catabolic machinery are unknown. This study reports the complex structure of NanR, a repressor of the N-acetylneuraminate (nan) genes responsible for N-acetylneuraminic acid catabolism, and its regulatory ligand, N-acetylmannosamine 6-phosphate (ManNAc-6P), in the human pathogenic bacterium Vibrio vulnificus. Structural studies combined with electron microscopic, biochemical, and in vivo analysis demonstrated that NanR forms a dimer in which the two monomers create an arched tunnel-like DNA-binding space, which contains positively charged residues that interact with the nan promoter. The interaction between the NanR dimer and DNA is alleviated by the ManNAc-6P-mediated relocation of residues in the ligand-binding domain of NanR, which subsequently relieves the repressive effect of NanR and induces the transcription of the nan genes. Survival studies in which mice were challenged with a ManNAc-6P-binding-defective mutant strain of V. vulnificus demonstrated that this relocation of NanR residues is critical for V. vulnificus pathogenesis. In summary, this study presents a model of the mechanism that regulates sialic acid catabolism via NanR in V. vulnificus.</P>

Effects of Bisphenol A and its Analogues on Adipogenesis Using 3T3-L1 Adipocytes

Hee-Seok Lee,Da-Woon Jung,YoungSun Song,Gyeong-Young Oh,Hyun-Suk Oh,Myung-Sil Hwang,Guiim Moon,Young Eui Koo 한국식품영양과학회 2016 한국식품영양과학회 학술대회발표집 Vol.2016 No.10

Evaluation of QTL Related SSR Marker Universality in Korean Rice Breeding Populations

Song, Moon-Tae,Lee, Jeom-Ho,Lee, Sang-Bok,Ku, Ja-Hwan,Cho, Youn-Sang,Song, Myung-Hee,Park, Sung-Ho,Hwang, Hung-Goo The Korean Society of Crop Science 2003 Korean journal of crop science Vol.48 No.1

If a quantitative trait loci (QTL) marker identified in a population is applicable to different populations (marker universality), this will not only reduce the labor and cost in marker assisted selection (MAS), but accelerate the application of molecular markers to real breeding programs. Present study aims to evaluate the defined QTL related markers from a population to a different breeding population for the MAS. Four rice breeding populations were subjected to seventy-five simple sequence repeat (SSR) markers which were already identified for their polymorphism information content (PIC) in the parents of the crossings. Among them, eight markers were evaluated for their correlation between presence of marker alleles and phenotypic expression in breeding populations. A reasonable level of polymorphism for the mapped markers originated from any sources of rice accessions was observed between crosses of any sources (marker repeatability). However, correlation between presence of markers and expression of the traits in rice breeding populations was not significant except for minor portion of traits and markers examined (failure of marker universality). In the present study, various strategies were discussed to develop new markers with universality of breeding application.

Intracellular $Ca^{2+}$ Mobilization and Beta-hexosaminidase Release Are Not Influenced by 60 Hz-electromagnetic Fields (EMF) in RBL 2H3 Cells

Hwang, Yeon-Hee,Song, Ho-Sun,Kim, Hee-Rae,Ko, Myoung-Soo,Jeong, Jae-Min,Kim, Yong-Ho,Ryu, Jeong-Soo,Sohn, Uy-Dong,Gimm, Yoon-Myoung,Myung, Sung-Ho,Sim, Sang-Soo The Korean Society of Pharmacology 2011 The Korean Journal of Physiology & Pharmacology Vol.15 No.5

The effects of extremely low frequency electromagnetic fields (EMF) on intracellular $Ca^{2+}$ mobilization and cellular function in RBL 2H3 cells were investigated. Exposure to EMF (60 Hz, 0.1 or 1 mT) for 4 or 16 h did not produce any cytotoxic effects in RBL 2H3 cells. Melittin, ionomycin and thapsigargin each dose-dependently increased the intracellular $Ca^{2+}$ concentration. The increase of intracellular $Ca^{2+}$ induced by these three agents was not affected by exposure to EMF (60 Hz, 1 mT) for 4 or 16 h in RBL 2H3 cells. To investigate the effect of EMF on exocytosis, we measured beta-hexosaminidase release in RBL 2H3 cells. Basal release of beta-hexosaminidase was $12.3{\pm}2.3%$ in RBL 2H3 cells. Exposure to EMF (60 Hz, 0.1 or 1 mT) for 4 or 16 h did not affect the basal or $1{\mu}m$ melittin-induced beta-hexosaminidase release in RBL 2H3 cells. This study suggests that exposure to EMF (60 Hz, 0.1 or 1 mT), which is the limit of occupational exposure, has no influence on intracellular $Ca^{2+}$ mobilization and cellular function in RBL 2H3 cells.

Effect of Extremely Low Frequency Electromagnetic Fields (EMF) on Phospholipase Activity in the Cultured Cells

Song, Ho-Sun,Kim, Hee-Rae,Ko, Myoung-Soo,Jeong, Jae-Min,Kim, Yong-Ho,Kim, Myung-Cheul,Hwang, Yeon-Hee,Sohn, Uy-Dong,Gimm, Yoon-Myoung,Myung, Sung-Ho,Sim, Sang-Soo The Korean Society of Pharmacology 2010 The Korean Journal of Physiology & Pharmacology Vol.14 No.6

This study was conducted to investigate the effects of extremely low frequency electromagnetic fields (EMF) on signal pathway in plasma membrane of cultured cells (RAW 264.7 cells and RBL 2H3 cells), by measuring the activity of phospholipase $A_2$ ($PLA_2$), phospholipase C (PLC) and phospholipase D (PLD). The cells were exposed to the EMF (60 Hz, 0.1 or 1 mT) for 4 or 16 h. The basal and $0.5\;{\mu}M$ melittin-induced arachidonic acid release was not affected by EMF in both cells. In cell-free $PLA_2$ assay, we failed to observe tbe change of $cPLA_2$ and $sPLA_2$ activity. Also both PLC and PLD activities did not show any change in the two cell lines exposed to EMF. This study suggests that the exposure condition of EMF (60 Hz, 0.1 or 1 mT) which is 2.4 fold higher than the limit of occupational exposure does not induce phospholipases-associated signal pathway in RAW 264.7 cells and RBL 2H3 cells.

生地黃, 乾地黃, 熱地黃이 細胞性免疫反應 및 體液性免疫反應에 미치는 影響

黃永明,高炳熙,宋一炳 慶熙大學校韓醫科大學韓醫學硏究所 1987 慶熙韓醫大論文集 Vol.10 No.-

양생초기의 진동시간 제어에 따른 콘크리트의 강도 변화

송규황(Song, Gyu Hwang),김종수(Kim, Jong Soo),김명식(Kim, Myung Sik),장희석(Jang, Hee Suk),김희성(Kim, Hee Sung) 한국콘크리트학회 2003 한국콘크리트학회 학술대회 논문집 Vol.2003 No.11