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윤기영,표경남,류문숙,김현식 서원대학교 교육대학원 2003 교육논총 Vol.7 No.-
The purpose of this study is to provide desirable directions for early childhood teacher education. To serve this purpose, the character on 'early childhood education theories' lectures are studied and examine the actual conditions of the 'subject education theories' lectures in university or college early childhood education Dept. And analysis the theories related subject matter. The 'early childhood education theories' lecture was characterized are as followers ; First, 'early childhood education theories' lecture means whole child education as not subject matter education. Second, 'early childhood education theories' lecture means school level education as primary(elementary) school level education. Third, 'early childhood education theories' lecture means generate subject education as like integrated curriculum, not like seperate subject education curriculum.
김영운,정숭룡,이승호,이종호,김창룡,박문성,류선열 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.4
Tuberculosis, a chronic infectious granulomatous disease, is preumed to be quite a rare entity. Because of the development of chemotherapy and the improvement of nutritional conditions, incidence of tuberculosis have reduced. For these reasons, tuberculosis may be overlooked in the differential diagnosis whenever dealing with a submandibular swelling. Diagnosis of tuberculous lymphadenitis consists of historical data, physical findings, laboratory tests and histologic examination. The treatment of choice seems to be surgical excision and long term antituberculosis chemotherapy. Surgery provides a rapid tissue diagnosis, because the histological examination of the excisional biopsy is the most reliable diagnostic test. This is the report of a case of tuberculous cervical lymphadenitis on left submandibular area with no evidence of the involvement of lung.
불균일 Winkler 탄성 기초위에 놓인 보의 자유진동과 안정성
최봉문,윤영식,윤충섭,류봉조 建陽大學校 1999 建陽論叢 Vol.- No.7
The paper deals with free vibration and stability analysis of a uniform Euler-Bernoulli beam resting on non-uniform Winkler elastic foundation. governing equations for the system are derived by using energy expressions. Solutions are approximately and numerically calculated by means of the finite element formulation. The solutions in the present paper are compared with other available ones without axial force. Finally, stability for cantilever and simply supported beams under a pure axial force is investigated.
정주성,김기영,김창룡,박문성,정숭룡,유선열,이승호 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.4
Vscularized calvarial bone flaps have been useful tools in the reconstuction of different type of bone defects in craniofacial surgery Vascularized bone transfer are often preferred to nonvascularized bone grafts because nonvascularized bone grafts are less resistant to infection, mot as mechanically strong, and do not survive well in a poorly vascularized bed. Potential advantages of vascularized outer table cavarial bone flap include proximity to the operative feild, membranous origin similar to that of the facial skeleton, maleability which allows for a variety of shapes and sizes, inconspicous donor sit scar. The following are the case reports of two patients who underwent craniofacial reconstruction suing vasularized outer table calvarial bone flap.
이승호,이성훈,김기영,김창룡,박문성,류선열,조규승 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.4
Carcinoma of the mouth accounts for approximately 5% of all carcinomas occurring in man. Carcinoma of the oral cavity develops as a result of invasion of malignant epithelial cells through the normally intact basal cell layer into subcutaneous and submucosal tissuse. The sofe palate and uvula may be involved in oral cancer but are not common sites. Early lesions of soft palate carcinoma appear as red, white, or mixed changes in the mucosa. The earliest symptom is mild sore throat. Advanced lesions interfer with swallowing and may cause a voice change. Although surgical method of soft palate carcinoma is successful, prognosis is relatively poor to swallowing and speech problem. Occasionally marginal recurrence may be developed. This article reports a case of squamous cell carcinoma occurred unusually in the soft palate and uvula. The case was treated with neoadjuvant chemotherapy, local radicalexcision and postoperative irradiation. Patient was followed up for 2 years. There was no tumor recurrence. The overall result including function was satisfactory.
RYU, Seung-Hee,KANG, Ki Mun,MOON, Soo Young,CHAI, Gyu Young,HONG, Joon Pio,CHO, Kyoung-Oh,KANG, Mun-Il,CHOI, Eun Kyung,LEE, Sang-wook Journal of Radiation Research Editorial Committee 2010 JOURNAL OF RADIATION RESEARCH Vol.51 No.5
<P>Concurrent chemotherapy with radiotherapy (CCRT) has been applied for the treatment of advanced stage of head and neck cancer patients. However CCRT is associated with several complications including mucositis, dermatitis, stomatitis, etc. This study was conducted to evaluate the therapeutic effect of systemically administrated recombinant human epidermal growth factor (rhEGF) in CCRT-induced oral mucositis in a mouse model. Oral mucositis was induced in male BALB/c mice through combination treatment with cisplatin (11 mg/kg, i.p.) and irradiation (17 Gy) of the head and neck area. rhEGF (1.0 mg/kg/day for consecutive 3 days) was administered systemically, and the therapeutic effect was determined by histological evaluation of the oral mucosa. To elucidate optimal dose of rhEGF on CCRT-induced mucositis, various concentrations (0.04–3 mg/kg) of rhEGF were injected for 3 days. Systemic rhEGF administration accelerated the recovery of body weight. Histologically, rhEGF-treated mice showed significantly increased epithelial cell layer thickness, basal cell number, and expression of Ki-67 compared to control mice. Most effective dose was 1 mg/kg among other doses tested. Systemic administration of 1 mg/kg of rhEGF reduces the severity of oral mucositis induced by CCRT in a mouse model, suggesting that rhEGF can be used for treating CCRT-induced mucositis during the cancer treatment.</P>
International Case Studies of Compliance Program (CP) on Nuclear Export Control
Mun-Young Ryu,Hyun-Jo Kim,In-Chul Kim,Seong-Mi Han,Ho-Jin Hwang 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.2
Strategic item export control aims to maintain international peace and safety and serves as a significant nuclear non-proliferation regime that directly impacts a nation’s security. Therefore, establishing an autonomous export control system at the state level is crucial, and one of the most efficient methods to achieve this is by enhancing an export company’s management system. Accordingly, many advanced countries, such as the United States, Europe, and Japan, have operated their own internal compliance programs (CP or ICP) to manage and screen the export of strategic items as a corporate social responsibility and risk mitigation measure. In Korea, which has a high dependence on trade, the need for CP was continuously confirmed, but the system was introduced in 2004, relatively late compared to other advanced countries. So far, the Korean government has made steady efforts to develop and establish the system and is actively encouraging businesses to obtain Compliance Program certification to autonomously manage strategic items. Major technologically advanced countries utilize technology transfer as a tool for economic sanctions, trade security, and strategic technology management, and they continue to strengthen their control regimes. In these countries, CP certification is considered a standard practice for export control among mid-sized and large enterprises. It serves as a vital risk management system that protects companies from unforeseen incidents. However, in Korea, the application of CP under the Foreign Trade Act is limited to dual-use items and does not extend to the nuclear export control system. Therefore, this paper analyzes international cases and CP requirements in countries like the United States, Japan, Europe, and Singapore. As a result of the review, the application of CP into Korea’s nuclear export control could be a coexistence means that can strengthen supply chain control as well as provide benefits not to impede technical research, international trade, and exchanges.
Ryu, Young Bae,Jeong, Hyung Jae,Yoon, So Young,Park, Ji-Young,Kim, Young Min,Park, Su-Jin,Rho, Mun-Chual,Kim, Se-Jae,Lee, Woo Song American Chemical Society 2011 Journal of agricultural and food chemistry Vol.59 No.12
<P>Influenza A virus infections continue to pose a major threat to humans and several animal species. Neuraminidase (NA) is one of the most promising targets for the development of drugs against influenza viruses because of its critical role in the viral life cycle. During the course of a search for NA inhibitors from edible natural sources, we found that the ethyl acetate layer of ethanol extracts of <I>Ecklonia cava</I> showed extremely high NA-inhibitory activity (72.1% inhibition at 30 μg/mL). Bioactivity-guided fractionation of the ethyl acetate layer yielded five phlorotannins, identified as phloroglucinol (<B>1</B>), eckol (<B>2</B>), 7-phloroeckol (<B>3</B>), phlorofucofuroeckol (<B>4</B>), and dieckol (<B>5)</B>. The inhibitory activities of these compounds (<B>1</B>–<B>5</B>) against NAs from group-1 (A/Bervig_Mission/1/18 [H1N1], A/PR/8/34 [H1N1]) and group-2 (A/Hong Kong/8/68 [H3N2], A/Chicken/Korea/MS96/96 [H9N2]) influenza A were evaluated to determine potencies and kinetic behavior. Analyses using various in vitro influenza A virus NA assays showed that all five phlorotannin derivatives were selective NA inhibitors. Of the phlorotannins, phlorofucofuroeckol (<B>4</B>) exhibited the most potent inhibitory activities toward group-1 NAs (IC<SUB>50</SUB> values, 4.5 and 14.7 μM), whereas dieckol (<B>5</B>) potently inhibited group-2 NAs. Kinetic analyses indicated that compounds <B>1</B>–<B>5</B> were all noncompetitive. Notably, these noncompetitive inhibitors synergized with oseltamivir to enhance the NA-inhibitory effects of oseltamivir.</P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/jf2007248'>ACS Electronic Supporting Info</A></P>