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      • Prevalence, Risk Factors and Disease Knowledge of Breast Cancer in Pakistan

        Asif, Hafiz Muhammad,Sultana, Sabira,Akhtar, Naveed,Rehman, Jalil Ur.,Rehman, Riaz Ur. Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11

        Breast cancer is the most common cancer in females all over the world with approximately one million new cases each year as well as one of second leading causes of death among females. In Pakistan, the most frequently diagnosed cancer among females is also breast cancer, accounting for nearly one in nine female patients. Its incidence in Pakistan is 2.5 times higher than that in neighboring countries like Iran and India. The risk factors associated with breast cancer are age, family history, early menarche, intake of combined estrogen and progestin menopausal hormones, alcohol consumption, physical inactivity, low socioeconomic status and lack of awareness regarding the disease. This mini-review article aims to provide awareness about breast cancer as well as an updated knowledge about the prevalence, risk factors and disease knowledge of breast cancer in Pakistan.

      • KCI등재후보

        Design of a low noise analog Front-End System for Sonar Signal Conditioning Receiver

        조종완,김성진,Muhammad Riaz ur Rehman,Khuram Shehzad,박영우,YoungGun Pu,이동헌,김형문,이강윤 한국과학기술원 반도체설계교육센터 2020 IDEC Journal of Integrated Circuits and Systems Vol.6 No.1

        This paper presents the design of a low noise analog front end system for sonar signal conditioning receiver with Parallel to Series Interface in very noisy environments. When measuring distances in the ocean through sonar, the input signal level to the receiver can change drastically depending on the distance between the transmitter and objects. Thus, a receiver with low sensitivity and a wide dynamic range is proposed in this work. In order to minimize the Input-Referred (IR) noise for the high sensitivity of the receiver, a low noise pre-amplifier is proposed and implemented, ultimately achieving a noise of 11 nV/√Hz at 50 kHz. The decimation factor of the digital filter placed after the SDM in the SD ADC can be controlled so as to reduce the power consumption. Through the use of these techniques in the SD ADC, we can implement reconfigurable sampling rates from 1.5 MS/s to 12.5 MS/s with low power consumption. In order to overcome the limitation of the number of pins for sensor application, a Parallel-to-Serial (P2S) interface is proposed and designed in the receiver. The Low Noise receiver in this paper is implemented in a 0.18 μm CMOS process and the die area is 14.44 mm2. The total power consumption of this chip under a supply voltage of 2.4 V is 46.8 mW. The measured sensitivity and dynamic range are -100 dBV and 100 dB, respectively. The measured SNDR at the output of the SD ADC is 82.02 dB when the input signal frequency and sampling frequency are 7 kHz and 6.25 Msps, respectively.

      • Medicinal Plants Combating Against Cancer - a Green Anticancer Approach

        Sultana, Sabira,Asif, Hafiz Muhammad,Nazar, Hafiz Muhammad Irfan,Akhtar, Naveed,Rehman, Jalil Ur.,Rehman, Riaz Ur. Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11

        Cancer is the most deadly disease that causes the serious health problems, physical disabilities, mortalities, and morbidities around the world. It is the second leading cause of death all over the world. Although great advancement have been made in the treatment of cancer progression, still significant deficiencies and room for improvement remain. Chemotherapy produced a number of undesired and toxic side effects. Natural therapies, such as the use of plant-derived products in the treatment of cancer, may reduce adverse and toxic side effects. However, many plants exist that have shown very promising anticancer activities in vitro and in vivo but their active anticancer principle have yet to be evaluated. Combined efforts of botanist, pharmacologist and chemists are required to find new lead anticancer constituent to fight disease. This review will help researchers in the finding of new bioactive molecules as it will focus on various plants evaluated for anticancer properties in vitro and in vivo.

      • Low noise, low power 5-Channel sonar signal conditioning receiver with 1.5 MS/s - 12.5 MS/s 16-bit sigma-delta ADC for ocean acoustic measurements

        김관태,김성진,Imran Ali,Muhammad Riaz Ur Rehman,이강윤 한국과학기술원 반도체설계교육센터 2018 IDEC Journal of Integrated Circuits and Systems Vol.4 No.4

        This paper presents a design of 5-channel receiver for ocean acoustic measurement in a very noisy environment. When measuring the distance in the ocean with the sonar signal, the input signal level to the receiver is drastically changed depending on the distance between the transmitter and objects. Thus, the receiver with high sensitivity and wide dynamic range is proposed in this work. In order to minimize the Input-Referred (IR) noise for high sensitivity of the receiver, low noise pre-amplifier is proposed and implemented achieving the noise of 29.6 nV/√Hz at 50 kHz. In addition, Sigma-Delta Analog-to-Digital Converter (SD ADC) with variable sampling rates is proposed by using clock splitting technique in the Sigma-Delta Modulator (SDM) core. Also, the decimation factor of the digital filter placed after the SDM in the SD ADC can be controlled to reduce the power consumption. Thanks to these techniques in the SD ADC, we can implement the reconfigurable sampling rates from 1.5 MS/s to 12.5 MS/s with low power consumption. In order to overcome the limitation of the number of pins for multi-channel application, Parallel-to-Serial (P2S) interface is proposed and designed in the receiver. The 5-channel receiver in this paper is implemented in 0.18μm CMOS process and die area is 14.44 mm2. The total power consumption of this chip is 46.8 mW under the supply voltage of 2.4 V. The measured sensitivity and dynamic range are -100 dBV and 100 dB, respectively. The measured SNDR at the output of the SD ADC is 82.02 dB when the input signal frequency and sampling frequency are 7 kHz and 6.25 Msps, respectively. The maximum phase error between 5 channels is measured to be ± 0.8 °.

      • KCI등재

        Interactive Effect of Cobalt and Nitrogen on Growth, Nodulation, Yield and Protein Content of Field Grown Pea

        Fahmida Mir Akbar,Mohsin Zafar,Abdul Hamid,Maqsood Ahmed,Abdul Khaliq,Muhammad Riaz Khan,Zahid ur Rehman 한국원예학회 2013 Horticulture, Environment, and Biotechnology Vol.54 No.6

        Pea (Pisum sativum L.) has increasing nutritional, commercial, and economical value, and initial low supply of N and Co is needed to increase nodulation, yield, and profit. A field experiment in 2010 was conducted at the University of Poonch Rawalakot located in the hilly region of the state of Azad Jammu and Kashmir, Pakistan. The aim of the study was to evaluate the effects of fertilization of N and Co on growth, nodulation, seed yield, seed composition of, and uptake of N and Co by pea plant. Treatments included three levels of N (0, 30, and 60 kg N·ha-1 and represented as N0, N30, and N60, respectively) combined with three levels of Co (0, 10, and 20 g Co·ha-1and represented as Co0, Co10, and Co20, respectively), and the control represented as N0Co0. Results indicated that most of the morphological characteristics were increased with N60. The greatest shoot length, root length, and chlorophyll content were recorded in the N60Co20. The number of root nodules increased from 6 in the control to 19with fertilization of N and Co. Yield responses to N–Co fertilization occurred to all rates, and the highest yield,2536 kg·ha-1, was observed in the treatment N60Co10. Total N and Co uptake in the plant (shoot + root + seed)ranged between 16-147% and 3-331% over the control, while seed protein increased by 13–198% over the control by application of N and Co. This study demonstrates that N- and Co-deficient soils are likely to produce crops with low yields and seeds with low protein levels, and therefore, appropriate management of soil N and Co could be an effective approach to increase and sustain pea production in the small holding mountain ecosystems.

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