FEM을 이용한 선삭가공 절삭조건의 영향 분석

임세환,송춘삼,홍석관,강정진,김주현 한국공작기계학회 2007 한국공작기계학회 추계학술대회논문집 Vol.2007 No.-

A plane strain finite element model is developed to simulate turning with continuous chip formation using adaptive remeshing during the thermal-mechanical coupled analysis. Comparisons between the experimental and simulation results for cutting forces are performed to validate FE analysis results. Influences of machining parameters such as depth of cut, cutting speed and feed rate on cuting force and shear angle are analyzed by Taguchi method. The more depth of cut and feed rate result in the increase of cutting forces, but the rates of increase are decrease due to the larger shear angle. As the cutting speed increases, von Mises stress of workpiece near the tool tip decreases because the strength of specimen decreases at high temperature above 500℃. This thermal effect on cutting force is negligible because the affected area is very localized and the average values of von Mises stress in the shear plane are the same among the diverse cutting parameters.

응급환자 의료정보의 공유 현황과 개선방안

오세현,이부수,김병철,김원,임경수 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Background: To manage the EMS(emergency medical services) system effectively, departments, such as fire stations, emergency information centers, hospitals, and The Ministry of Health and Welfare, should exchange information that they own and/or gather during patient care and/or transportation. Medical records and information are very important for continuing the patient's care and for deciding on a treatment plan, but medical information is not exchanged fully in spite of its importance. Method: We analyzed the transfer medical reports that were written by medical doctors who transferred emergency patients to our hospital. The contents and the accuracy of the transfer medical records were analyzed and graded into 4 groups. Group A was fully described and was equipped with diagnosis, laboratory data, X-ray fi1ms; group B had a diagnosis and full laboratory data; group C had a diagnosis, but only partial laboratory data; and group D had only a diagnosis. Results: Among 38,214 patients who visited our hospital from Jan. 2001 to Jun. 2001, 7,031 cases were transferred from other hospitals with transfer medical records. According to the accuracy and important contents of the transfer records, Group A occupied 1.9%, group B 5.2%, group C 32.5%, and group D, with only a diagnosis,60.4%. In the case of our hospital, we delivered all emergency medical information by written paper(transfer note), E-mail, and web-based information system(caber-AMC) to the doctors concerned with managing the patient. However, 93% of the medical records of patients transferred from other hospital contained insufficient information to adequately care for the emergency patients. In addition, most of the transferred patients had been transorted without prior information about transportation. Conclusion: Within the near future, a medical information center equipped with a computerized system should be operated to exchange medical data. As most general hospitals are operating the OCS(order communication system), EMR(electronic medical record), telemedicine, and PACS(picture-archiving communication system), medical information can be exchanged freely in real time if a code standard and HL7(Health Level 7) can be established.

두경부 악성 림프종의 면역조직화학적 유형분석 및 Epstein-Barr virus의 검출

김성현,전세영,임동명 조선대학교 부설 의학연구소 1999 The Medical Journal of Chosun University Vol.24 No.1

Background and Objectives : The Epstein-Barr virus(EBV) is a human herpes virus which causes infectious mononucleosis and is associated with such human cancers as Burkitt's lymphoma and nasopharyngeal carcinoma. However, the role of EBV as a causative factor in other head and neck tumors is not fully elucidated. Malignant lymphoma is a tumor of the immune system which is commonly known as a non-epithelioid tumor of the head and neck region. Recent studies have suggested a probable etiologic association between EBV and lymphomas. This study was performed to investigate the strength of the association of EBV with malignant lymphoma and to carry out an immunohistochemical classification. Materials and Methods : Twenty one cases of non-Hodgkin's lymphoma tissues in the head and neck were used. Immunohistochemical staining was carried out with EBV protein, CD20 and CD3. Results : Among the 21 cases of malignant lymphoma, 9(43%) of the cases were of B cell lineage, 10(48%) of the cases of T cell lineage and 2(10%) of the cases were of an unclassifiable type. The commonest histopathologic type were diffuse large cell types and diffuse mixed types in 8(38%) of the cases. All 6 cases(100%) of nasal/paranasal sinus lymphoma were T-cell lymphoma. The detection rate of EBV in malignant lymphoma tissue was 52%. EBV was detected in 5 cases(56%) of B-cell lineage and 6 cases(60%) of T-cell lineage. Among 6 cases of nasal/paranasal sinus T-cell lymphoma, 4(67%) were positive for anti-human EBV protein. In the positive cases, a large number of the neoplastic cells and infiltrated lymphocytes showed strong nuclear signals. Conclusion : These results suggest that most nasal/paranasal sinus lymphomas are T-cell type neoplasms and EBV probably plays an etiologic role in the pathogenesis of group nasal/paranasal sinus T-cell lymphomas.

Terfenadine과 Ketoconazole 복용 후 발생된 Torsades de pointes 심실 빈맥증의 치험 1례

김세경,이기중,유승진,박일영,박승현,임근우,이원재,강동헌 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

Torsades de pointes is a form of polymorphic ventricular tachycardia that is associated with prolongation of the QT interval, characterized by QRS complexes of progressively changing amplitude and contour that seem to revolve around the isoelectric line. The most common cause of Torsades de pointes induced by antiarrhythmic agents, occupying in certain drugs or toxin, electrolyte disturbance, congenital QT prolongation syndrome. Cardiotoxicity terfenadine, in overdose a widely used, nonsedating antihistamine, has been reported. Case after administration of terfenadine and ketoconazole causing syncope and torsades de pointes have been reported in recommended dose. We report a case of QT prolongation with torsades de pointes after therapeutic administration of terfenadine, a long acting histamine H1 receptor antagonist, together with ketoconazole, an antifungal preparation. The patient is a 43-year-old female, who experienced palpitation, dizziness and syncopal episoders after coadministration of terfenadine and ketoconazole, for a fungal infection of the skin. The ECG showing typical episodes of torsades de pointes with QT prolongation. Magnesium sulfate was given, torsades de pointes did not recur. The patient was discharged with improved condition.

영광군 홍농읍 주변 해역의 동물플랑크톤 분포

金世華,姜演植,嚴熙文,林東賢 龍仁大學校 1995 용인대학교 논문집 Vol.11 No.-

Studies on the seasonal distribution of zooplankton were carried out in 1994 in waters off Yongkwang Atomic Power Plant. Zooplankton samples were collected four times seasonally at six selected stations. Forty - three taxa of zooplankton were distributed and 25 species representing 21 copepods, 2 chaetognaths, 1 protozoan and appendicularian were identified to species level. Zooplankton abundance varied between 840-42, 014 indiv. m-3 and were recorded the highest abundance in September and the lowest in February. Seasonal succession in the dominant species was observed from winter and spring with Acartia omorii to summer and autumn with A. pacifica and Paracalanus indicus. With the prevalence of ueritic copepods all the year round, i.e., A. omorii, A. pacifica and P. indicus, the studied waters were revealed to have the typical zooplankton fauna in coastal waters of the Yellow Sea.

복합재료의 고속드릴링 가공시 칩형태에 관한 연구

성인식,임세환,김주현 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

Composite material is combined with two or more chemical ingredient and different components. FRP has been widely used for the structure of aircraft, ships, automobiles, sporting goods and other machines because of their high specific strength, high specific stiffness and excellent fatigue strength. Recently, the development of machine tool and cutting tool greatly relies on high speed process to satisfy high precision, high efficient machining, shortened process time to maximize material removal rate (MRR) through high cutting speed and feed speed. The research molded CFRP, GFRP as stacking sequence methods of two direction (orientation angle 0° and 0°/90°) hand lay-up, drilled molded plates using cemented carbide drill and examined chip shapes, surface roughness properties.

주의력결핍 과잉행동장애 아동에서 틱 장애 동반 여부에 따른 확산 텐서 영상 비교 연구

최지욱,임명호,이창화,박진균,손정우,심세훈,유인규,강현수,정범석 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.5

Objectives : Diffuse tensor imaging (DTI) was applied to explore the difference in regional distribution and extent of white matter (WM) abnormalities in boys with Attention-deficit/hyperactivity disorder (ADHD) versus boys with comorbid ADHD and tic disorders. Methods : Fifteen boys with ADHD (mean age 9.3 +1.8), 24 ADHD boys with chronic tic disorder or Tourette's disorder(9.9 =b 1.2) and 9 age-, gender-matched controls (9.2 d= 1.8) received DTI assessments. Fractional Anisotropy (FA) maps of WM were compared between groups with a voxel-wise analysis after intersubject registration to MNI space. Results : Bo groups, ADHD group and ADHD with tic disorder group, commonly showed decreased FA than healthy control group in left cerebellar middle peduncle and right frontal lobe, increased FA in right middle occipital WM. In the common areas of left cerebellar middle peduncle and right middle occipital WM, comorbid group showed broader areas of significant FA. The comorbid group also showed increased FA in right cerebellar peduncle, additionally. Conclusion : The findings in ADHD group support previous ADHD hypothesis of the functional abnormalities in corticocerebellar circuit, and suggest that ADHD might have more complicated pathology of neuronal circuit including occipital visual system. The comorbid group showed common areas of overlapping but more extensive abnormalities and also had additional WM abnormalities. ADHD with chronic tic disorders may represent a severe form of ADHD with additional regions of abnormal connectivity.

Plyometric Training과 비타민 C 투여가 남고생의 체력, 혈중 젖산, 암모니아 및 젖산탈수소효소에 미치는 영향

장준원,김세종,이현미,서혜림,조현숙,고정림,염종우,예정복,백영호 釜山大學校 附設 體育科學硏究所 2003 體育科學硏究所 論文集 Vol.19 No.-

The purpose of this was to examine the effect of plyometric training and vitamin C ingestion on physical fitness and fatigue substance....

시클러 캡슐(세파클러 250㎎)에 대한 경보세파클러 캡슐의 생물학적동등성

조혜영,강현아,김세미,박찬호,오인준,임동구,문재동,이용복 한국약제학회 2005 Journal of Pharmaceutical Investigation Vol.35 No.1

The purpose of the present study was to evaluate the bioequivalence of two cefaclor capsules, Ceclor (Lilly Korea Co., Ltd.) and Kyongbocefaclor (Kyongbo Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The release of cefaclor from the two cefaclor formulations in vitro was tested using KP VIII Apparatus II method with various dissolution media (pH 1.2. 4.0. 6.8 buffer solution and water). Twenty four healthy male subjects. 22.96±1.52 years in age and 67.03±7.90 kg in body weight, were divided into two groups and a randomized 2x2 cross-over study was employed. After one capsule containing 250 mg of cefaclor was orally administered, blood was taken at pre-determined time intervals and the concentrations of cefaclor in serum were determined using HPLC method with UV detector. The dissolution profiles of two formulations were similar at all dissolution media. In addition. the pharmacokinetic parameters such as AUC_(t), C_(max) and T _(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_(t). C_(max) and untransformed Tmaa. The results showed that the differences between two formulations based on the reference drug, Ceclor. were -1.90%, 2.68% and -7.60% for AUCt, C_(max) and T_(max), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (e.g., log 0.91-log 1.06 and log 0.92-log 1.18 for AU', and C_(max), respectively). Thus. the criteria of the KFDA bioequivalence guideline were satisfied, indicating Kyongbocefaclor capsule was bioequivalent to Ceclor capsule.

고유 0 Flow에서 s의 포락선의 몇 가지 특성화

김영기;유지현;임세현 명지대학교 자연과학연구소 2004 자연과학논문집 Vol.23 No.-

We introduce the notion of an enveloped subgroup of T. We find some characterization of the enveloped subgroup of T and the relation with the kernel of the character. 본 논문은 T의 포락된 부분군의 개념을 소개하였고, T의 포락된 부분군의 몇 가지 특성화와 지표(character)의 핵(kernel)과의 관계를 연구하였다.