고강도 콘크리트 보부재의 구속효과 및 전단거동에 관한 연구

이수형,송재호,장일영 金烏工科大學校 2000 論文集 Vol.21 No.-

Even though concrete is a good material having considerably high durability, problems in durability and reliability take place sometimes when using it. One of the problems is involved in compaction work which depends greatly on human workability. So if concrete which doesn't need compaction work is possible, a higher promotion in reliability of concrete structures is also possible. But problems in reliability can take place depending on the concrete filling condition, even when high-performance concrete is used. High strength concrete beams are dealt concerning shear behavior and confinement in this study. series of high strength concrete beam specimens are tested to investigate their behavior and to determine their ultimate shear stresses. Test variables consist of concrete filing condition, compressive strength of concrete, and shear stirrup ratio. Two cases of concrete filling condition are prepared intentionally in such a way that specimens are cast soundly to obtain perfect filling condition in first case. In second case, in order to simulate the state of poor workmanship, poor workability and unsatisfactory compaction, up to a half the beam section good concrete is filled while poor concrete is filled to the other half. From the test results, load-displacement responses, formation of shear cracks, types of shear failure, and shear strength are analyzed and evaluated. The have no effects of different concrete filling conditions and arrangement of stirrups on the ultimate strength of structures. But, the habe a great influence of concrete filling condition and arrangement of stirrups on total reserved shear force and ductile of structures.

胃疾患의 食餌療法

강미경,김미숙,김선숙,김수향,양이선 효성여자대학교 가정대학 학도호국단 1987 家政大論集 Vol.6 No.-

The circumstance being surrounded with a rapidly changing society causes us to build up manystresses during our modern life. For this reason, there is increasing the occurrence of gastroentericdisorder in frequency. The dietary treatment of gastroenteric disorder requires to prepare the program necessary fora meal's amount quality and cookery with careful attention. In addition, it is essential for gastroentericpatients to fully supplement the needed nutritive substance depending on the degree of the trouble,by controling their mealtimes. Consequently, the successful dietary treatment entirely depends uponthe close cooperation between the patient involving his family and doctors and dietitians becausethe patient has to observe the standard of the programed dietary treatment. And it also is very impor-tant that the person who prepares table for these patients, attempts to improve their appetite, bysupplying foods suitable for their digestion and taste on the basis of the dietary treatment's standard. Several mental elements of gastroenteric patients have great effect upon the recovery of their di-sorder so that their family and nurses must lead these patients to stabilize their mind and to berestored to health as well as the adequate medical treatment.

현장환경의 원격제어를 위한 센서신호처리 및 전송시스템의 개발

박종식,유상대,김항준,이종국,윤태수 경북대학교 센서기술연구소 1991 센서技術學術大會論文集 Vol.2 No.1

여러 분야에 걸쳐서 각종 센서의 개발과 센서신호 처리 시스템의 개발이 활발히 이루어지고 있다. 본 논문에서는 산업 현장 및 대형 건물내에서 입력되는 환경에 대한 센서 신호를 신호처리하여 최적 환경 상태를 유지하는 시스템을 개발하였다. Locall controller는 각각 독립된 마이크로 컴퓨터를 내장한 인텔리전트 형식으로 구성되고 이들이 전용 LAN을 통해 중앙통제 장치와 통신한다.

The Benefits of Combination Therapy with Esomeprazole and Rebamipide in Symptom Improvement in Reflux Esophagitis: An International Multicenter Study

( Su Jin Hong ),( Soo-Heon Park ),( Jeong Seop Moon ),( Woon Geon Shin ),( Jae Gyu Kim ),( Yong Chan Lee ),( Dong Ho Lee ),( Jae Young Jang ),( Jae J. Kim ),( Hang-Lak Lee ),( Sang Woo Lee ),( Young H 대한소화기기능성질환·운동학회 2016 Gut and Liver Vol.10 No.6

Background/Aims: To investigate the effects of esomeprazole and rebamipide combination therapy on symptomatic improvement in patients with reflux esophagitis. Methods: A total of 501 patients with reflux esophagitis were randomized into one of the following two treatment regimens: 40 mg esomeprazole plus 300 mg rebamipide daily (combination therapy group) or 40 mg esomeprazole daily (monotherapy group). We used a symptom questionnaire that evaluated heartburn, acid regurgitation, and four upper gastrointestinal symptoms. The primary efficacy end point was the mean decrease in the total symptom score. Results: The mean decreases in the total symptom score at 4 weeks were estimated to be -18.1±13.8 in the combination therapy group and -15.1±11.9 in the monotherapy group (p=0.011). Changes in reflux symptoms from baseline after 4 weeks of treatment were -8.4±6.6 in the combination therapy group and -6.8±5.9 in the monotherapy group (p=0.009). Conclusions: Over a 4-week treatment course, esomeprazole and rebamipide combination therapy was more effective in decreasing the symptoms of reflux esophagitis than esomeprazole monotherapy. (Gut Liver 2016;10:910-916)

Outcomes and Complications of Oblique Lateral Interbody Fusion as a Surgical Option in Elderly Patients (Over 70 Years Old) with Degenerative Spinal Disease

Lee Yong Min,Son Dong Wuk,Oh Bu Kwang,Lee Su Hung,Lee Jun Seok,Kim Young Ha,Sung Soon Ki,Lee Sang Weon,Song Geun Sung 대한말초신경학회 2023 The Nerve Vol.9 No.2

Objective: As Korea has become a super-aging society, the number of elderly patients with degenerative spinal disease has steadily increased. This study aimed to evaluate the usefulness of oblique lumbar interbody fusion (OLIF) by comparing the results and complications between OLIF and open spinal fusion in elderly patients with degenerative spinal disease.Methods: Thirty-one patients underwent one-level posterior lumbar interbody fusion (PLIF), and 35 patients underwent one-level indirect decompression OLIF. The clinical outcomes of the two patient groups were analyzed using the visual analog scale (VAS) and Oswestry Disability Index (ODI). Through a comparative analysis of pre- and post-operative images, we measured changes in disc height (DH) and foraminal height (FH), and investigated the occurrence of subsidence in each patient group. The cross-sectional area was measured using magnetic resonance imaging pre- and post-operatively in OLIF.Results: The pre-operative VAS and ODI scores were similar between the two groups and tended to improve post-operatively. In the OLIF group, the estimated blood loss (EBL) was significantly lower, DH and FH gains were more frequent, DH and FH maintenance was better, and cage subsidence occurred less frequently. In OLIF, psoas paresis and approach-site hematoma occurred; however, all patients with psoas paresis recovered without further treatment before discharge. In the PLIF group, dural tears occurred in four patients who recovered without revision surgery. Conclusion: OLIF enables indirect decompression, reduced EBL, shorter hospitalization, and lesser subsidence. OLIF is considered a beneficial, minimally invasive surgical method for elderly patients.

FYN promotes mesenchymal phenotypes of basal type breast cancer cells through STAT5/NOTCH2 signaling node

Lee, Ga-Hang,Yoo, Ki-Chun,An, Yoojeong,Lee, Hae-June,Lee, Minyoung,Uddin, Nizam,Kim, Min-Jung,Kim, In-Gyu,Suh, Yongjoon,Lee, Su-Jae Nature Publishing Group UK 2018 Oncogene Vol.37 No.14

<P>Basal type breast cancer is the most aggressive and has mesenchymal features with a high metastatic ability. However, the signaling node that determines the basal type features in breast cancer remains obscure. Here, we report that FYN among SRC family kinases is required for the maintenance of basal type breast cancer subtype. Importantly, FYN enhanced NOTCH2 activation in basal type breast cancer cells through STAT5-mediated upregulation of Jagged-1 and DLL4 NOTCH ligands, thereby contributed to mesenchymal phenotypes. In addition, we found that high levels of FYN persist in basal type breast cancer cells by a positive feedback loop between FYN and STAT5. FYN interacted directly with STAT5 and increased p-STAT5 that further acts as a transcription factor for FYN. Taken together, our findings demonstrate a pivotal role of FYN and its downstream effectors in maintaining the basal type features in breast cancer.</P>

Bovine Genome-wide Association Study for Genetic Elements to Resist the Infection of Foot-and-mouth Disease in the Field

Lee, Bo-Young,Lee, Kwang-Nyeong,Lee, Taeheon,Park, Jong-Hyeon,Kim, Su-Mi,Lee, Hyang-Sim,Chung, Dong-Su,Shim, Hang-Sub,Lee, Hak-Kyo,Kim, Heebal Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.2

Foot-and-mouth disease (FMD) is a highly contagious disease affecting cloven-hoofed animals and causes severe economic loss and devastating effect on international trade of animal or animal products. Since FMD outbreaks have recently occurred in some Asian countries, it is important to understand the relationship between diverse immunogenomic structures of host animals and the immunity to foot-and-mouth disease virus (FMDV). We performed genome wide association study based on high-density bovine single nucleotide polymorphism (SNP) chip for identifying FMD resistant loci in Holstein cattle. Among 624532 SNP after quality control, we found that 11 SNPs on 3 chromosomes (chr17, 22, and 15) were significantly associated with the trait at the p.adjust <0.05 after PERMORY test. Most significantly associated SNPs were located on chromosome 17, around the genes Myosin XVIIIB and Seizure related 6 homolog (mouse)-like, which were associated with lung cancer. Based on the known function of the genes nearby the significant SNPs, the FMD resistant animals might have ability to improve their innate immune response to FMDV infection.

관측 오차와 위성의 기하 구조가 GNSS 반송파 미지정수 타당성 검증 시험에 미치는 영향

이흥규(Lee Hung-Kyu),이인수(Lee In-Su) 대한토목학회 2004 대한토목학회논문집 D Vol.24 No.5D

Randomized, Multi-center Phase II Trial of Docetaxel Plus Cisplatin Versus Etoposide Plus Cisplatin as the First-line Therapy for Patients with Advanced Non-small Cell Lung Cancer

Nam-Su Lee,Hee-Sook Park,Jong-Ho Won,Dae-Sik Hong,Su-Taek Uh,이상재,Joo-Hang Kim,Se-Kyu Kim,Myung-Ju Ahn,최정혜,Suk-Chul Yang,Jung-Ae Lee,Keun-Seok Lee,Chang-Yeol Yim,Yong-Chul Lee,Chul-Soo Kim,Moon-Hee Lee 대한암학회 2005 Cancer Research and Treatment Vol.37 No.6

Purpose: We prospectively conducted a multi-center,open-label, randomized phase II trial to compare the efficacy and safety of docetaxel plus cisplatin (DC) and etoposideplus cisplatin (EC) for treating advanced stage non-small cell lung cancer (NSCLC).Materials and Methods: Seventy-eight previously untreated patients with locally advanced, recurrent or metastatic NSCLC were enrolled in this study. The patientsreceived cisplatin 75 mg/m2 on day 1 and either docetaxel 75 mg/m2 on day 1 or etoposide 100 mg/m2 on days 1 to 3 in the DC or EC arm, respectively, every 3 weeks.Results: The objective response rate was 39.4% (15/38) and 18.4% (7/38) (p=0.023) in the DC and EC arms, respectively. The median time to progression (TTP) was5.9 and 2.7 months (p=0.119), and the overall survival was 12.1 and 8.7 months (p=0.168) in the DC and EC arms, respectively. The prognostic factors for longer survival were an earlier disease stage (stage III, p=0.0095), the responders to DC (p=0.0174) and the adenocarcinoma histology (p=0.0454). The grades 3 and 4 toxicities were similar in both arms, with more febrile neutropenia (7.9% vs. 0%) and fatigue (7.9% vs. 0%) being noted in the DC arm.Conclusion: DC offered a superior overall response rate than does EC, along with tolerable toxicity profiles, although the DC drug combination did not show significantlyimproved survival and TTP.

서울시 정비사업의 주택공급 특성 및 공급가능 물량 분석

이삼수(Lee, Sam-Su),이석제(Lee, Seo-kje),권치흥(Kwon, Chi-hung) 한국부동산정책학회 2020 不動産政策硏究 Vol.21 No.2

This paper analyzed the contribution of housing supply based on the progress of redevelopment and reconstruction projects among the improvement project in Seoul. By analyzing the project promotion stage of the improvement project, the amount of housing available from 2020 to 2035 was calculated. The implications of the improvement project for the housing supply policy are as follows. First, housing supply characteristics accounted for over 70% of apartments compared to the total number of homes supplied in the 2000s, but fell below 50% after 2010. Second, from 2005 to 2018, the contribution of the housing supply to the improvement project compared to the new number of housing supply has been continuously decreasing to about 22.2%. Third, it is expected that total of 390,000 units will be supplied by 2035 by the improvement project. And it is expected to supply 85,000 units by 25, 16,200 units by 26-30, and 14,200 units by 30. Lastly, the amount of housing available for each period of completion of the improvement project is expected to surge to 15,000 units annually from 20 to 25 years and 32,000 units from 26 to 30 years. Therefore, the improvement project takes a long period of time, and there is a limit to the short-term housing supply policy. It is necessary to convert the old housing in the down town into a housing policy for rational housing stock management.