Overseas Review on the In-situ Demonstration of EBS for IN-DEBS Development

Minsoo Lee,Heui-Joo Choi,Jong-Youl Lee,Changsoo Lee,Jae-Owan Lee,Inyoung Kim 한국방사성폐기물학회 2014 방사성폐기물학회지 Vol.12 No.2

본 연구에서는 한국원자력연구원 부지 내 KURT 연구시설에 심지층 처분실증시험을 수행할 목적으로 사전 해외현황조사를실시하였다. 고준위폐기물 심지층 처분을 목적으로 지하연구시설을 구축한 나라들을 대상으로 현재 수행되었거나, 수행이진행 중인 공학적방벽 성능평가 시험들을 조사하였다. 주요 실증시험으로는, 스웨덴/프랑스 TBT, 스웨덴 LOT, 스위스 HEE,벨기에 PRACLAY, 스페인 FEBEX, 일본 HORONOBE, 및 캐나다 BCE 등이었다. 각 실증시험에 대하여 시험의 목적, 시험체의 구성, 시험조건, 세부 구성도, 측정 항목, 측정기기, 및 도출된 결과 등을 구체적으로 조사하였으며, 시험결과보다는 시험목적 및 시험물의 구축방법 파악에 더 집중하였다. 왜냐하면, 각국의 공학적방벽 성능시험방법의 검토를 통해 향후 KURT에서 추진하게 될 공학적방벽 실증시설의 설계에 도움을 얻고, 다양한 성능시험을 동시에 수행할 수 있도록 하기 위해서였다. 향후 KURT 확장을 통해 공학적방벽 성능시험 터널을 확보하고, 중규모의 성능 시험시연을 추진하게 될 예정이다. 본 기술검토를 통해 이 때 추진할 시험내역과 시험체의 구성 및 크기 등의 상세 설계에 필요한 기초적인 지식을 얻고자 하였다.

초음속 연소기에서 케로신을 사용한 벽면 냉각의 효과 측정

양인영(Inyoung Yang),이석환(Seok-hwan Lee),이양지(Yang-ji Lee),이상훈(Sang-hoon Lee),이경재(Kyung-jae Lee) 한국추진공학회 2019 한국추진공학회 학술대회논문집 Vol.2019 No.11

Change of fatty acid composition in the seed oil of diacylglycerol acyltransferase 7 and 2 knockout camelina by CRISPR-Cas9 system

Kyeong-Ryeol Lee,Yumi Yeo,Jihyea Lee,Semi Kim,Chorong Im,Inyoung Kim,Juho Lee,Seon-Kyeong Lee,Hyun Uk Kim,Mi Chung Suh 한국육종학회 2023 한국육종학회 공동학술발표집 Vol.2023 No.-

Patient Safety Culture and Speaking Up Among Health Care Workers

Lee Seung Eun,Dahinten V. Susan,서자경,Park InYoung,Lee Mi Young,Han Hye Sung 한국간호과학회 2023 Asian Nursing Research Vol.17 No.1

Purpose: Although previous research showed the importance of safety culture on health care workers' speaking up behaviors, it is not clear how particular safety culture domains are associated with the speaking up behaviors of hospital staff. Also, researchers have suggested that health care workers’ speaking up behaviors vary by profession, but there has been limited research into such differences. Thus, this study examined differences in perceptions of patient safety culture and the promotive and prohibitive speaking up behaviors of health care workers by profession and investigated the relationships between patient safety culture and the two types of speaking up behaviors. Methods: A descriptive correlational study was conducted using secondary data collected through an online survey of health care workers at a private, nonprofit, tertiary-level teaching hospital in South Korea. The sample (N ¼ 831) consisted of nurses (54.0%), physicians (13.0%), and other licensed and unlicensed hospital personnel (33.0%). Analyses of variance were conducted to examine differences in study variables by profession. Hierarchical regression analyses were conducted to evaluate the effects of the seven patient safety culture factors on promotive and prohibitive voice after controlling for tenure and profession. Results: Perceptions of safety culture and promotive voice behaviors were higher for physicians compared with nurses. Communication openness, reporting patient adverse events, and unit supervisors' and hospital managements’ support for patient safety were significant predictors of both types of voice behaviors. Conclusion: Hospital administrators and unit managers should create a supportive environment where staff feel free to voice their concerns and suggestions. They should also pay attention to the varying perspectives held by different groups of hospital workers and their different voice behaviors. Knowing which dimensions of patient safety culture are most strongly related to health care workers’ voice behaviors can guide patient safety improvement activities in health care organizations.

The Effects of Visualizing Emotions in Online Textual Conversation

Inyoung Park(박인영),Suhyun Lee(이수현),Daeho Lee(이대호) 대한인간공학회 2020 대한인간공학회 학술대회논문집 Vol.2020 No.6

Delayed deterioration of wild-simulated-ginseng using essential oil-nanostructured lipid carrier-embedded hydrogels

Inyoung Lee,Juah Chung,Gyubin Lee,Seokwon Lim,Choongjin Ban 한국산업식품공학회 2023 학술대회 및 심포지엄 Vol.2023 No.11

THE COMBINED EFFECTS OF SOCIAL CONTEXT AND AROUSAL POTENTIAL CUES ON INTENTION TO ATTEND CULTURAL EVENTS

Inyoung Lee,Sang-Hoon Kim,Jisu Yi 글로벌지식마케팅경영학회 2023 Global Marketing Conference Vol.2023 No.07

Organizations are increasingly implementing recommendation systems on their websites. A growing body of research is focusing on how the characteristics of online message content affect consumers’ consumption intentions, taking into account consumers’ static personal information, such as demographics. However, limited research has explored how the social context of consumers and online message content characteristics can affect the consumers’ intention to consume events. To address this gap, the present study investigates the joint effects of consumers' social context and arousal potential cues on their intention to attend cultural events. Based on the Target-arousal level theory, we suggest that people who anticipate solo consumption (i.e., accompanied by no one) will tend to attend cultural events promoted by a low arousal potential cue (A calming experience.), while those who anticipate social consumption (i.e., accompanied by one or more companions) will tend to attend cultural events promoted by a high arousal potential cue (An exciting experience”). Furthermore, we argue that anticipated enjoyment will mediate this relationship. The joint impact of the social context and arousal potential cues of a cultural event on consumers' intention to attend, as well as the mediating role of anticipated enjoyment, were demonstrated through two studies. The use of message cues and personalized recommendation algorithms as tools to target consumers and improve attendance rates is discussed. References available upon request.

Inhibitory Activities of Diabetes Mellitus in Coccinia grandis during Fruit Ripening

Inyoung Lee,Nami Joo 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

Diabetes mellitus is a disease caused by the secretion of insulin, a hormone regulates blood glucose. Prolonged consumption of antidiabetic drugs may lead to undesired side effects. Therefore, formulation of plant based medicines is a good strategy. The enzyme inhibitory property of Coccinia grandis (C. grandis) during different stages of fruit ripening are yet to be reported. Hence, C. grandis was classified into immature, mature and ripen fruits, and the inhibitory activities of α-amylase and α-glucosidase were determined. As a result, α-amylase inhibitory activity in C. grandis extract (5 mg/mL) of immature fruits was highest (93.4%), followed by mature (85.4%) and ripe (70.3%) fruits. The α-glucosidase inhibitory activity was 21.3% in immature fruits, 13.6% and 5.2% in mature and ripe, decreasing significantly as the C. grandis ripened. C. grandis contains the physiological active substances, especially flavonoids are involved in the inhibitory activity of carbohydrate-related enzymes. In this study, C. grandis extract of immature fruits had the highest inhibitory activity, thus it is considered to exert a potential as a new antidiabetic treatment.

The DNA replication protein Cdc6 inhibits the microtubule-organizing activity of the centrosome

Lee, Inyoung,Kim, Gwang Su,Bae, Jun Sung,Kim, Jaeyoun,Rhee, Kunsoo,Hwang, Deog Su American Society for Biochemistry and Molecular Bi 2017 The Journal of biological chemistry Vol.292 No.39

<P>The centrosome serves as a major microtubule-organizing center (MTOC). The Cdc6 protein is a component of the pre-replicative complex and a licensing factor for the initiation of chromosome replication and localizes to centrosomes during the S and G(2) phases of the cfell cycle of human cells. This cell cycle-dependent localization of Cdc6 to the centrosome motivated us to investigate whether Cdc6 negatively regulates MTOC activity and to determine the integral proteins that comprise the pericentriolar material (PCM). Time-lapse live-cell imaging of microtubule regrowth revealed that Cdc6 depletion increased microtubule nucleation at the centrosomes and that expression of Cdc6 in Cdc6-depleted cells reversed this effect. This increase and decrease in microtubule nucleation correlated with the centrosomal intensities of PCM proteins such as gamma-tubulin, pericentrin, CDK5 regulatory subunit-associated protein 2 (CDK5RAP2), and centrosomal protein 192 (Cep192). The regulation of microtubule nucleation and the recruitment of PCM proteins to the centrosome required Cdc6 ATPase activity, as well as a centrosomal localization of Cdc6. These results suggest a novel function for Cdc6 in coordinating centrosome assembly and function.</P>

국가생명윤리심의위원회에 대한 운영평가와 향후 정책제언

이인영,이정애,이동익,양윤선 홍익대학교 2008 홍익법학 Vol.9 No.2

생명과학기술과 관련된 안전과 윤리 이슈는 여러사회집단간의 의견차이가 심하고 갈등이 분명하게 드러나는 민감한 사안의 성격을 가지고 있다. 급속히 빨라지는 생명과학의 속도에 비해서 이에 따른 안전과 윤리에 대한 대응은 집단별로 각기 차이가 있으며, 이러한 문제에 대한 의견 차이는 제대로 된 공론화의 과정을 거치기보다는 자칫하면 소모적인 논쟁과 갈등으로 비화 될 우려가 크다. 이러한 생명과학연구와 관련된 정책의 민감성으로 인해 큰 틀에서의 조정과 합의를 이루어가는 절차를 요구될 수밖에 없으며, 국가생명 윤리심의위원회가 조정기구로서의 역할을 담당해야만 하는 의미가 바로 여기에 있다. 우리나라의 국가생명윤리심의위원회의 성격은 심의 업무를 행하지만 대통령 직속 자문위원회의 성격을 가지고 있다. 조정기구로서의 독립성을 유지하기 위해 생명과학 연구에 의해서 야기될 수 있는 사회적 · 윤리적 논란에 대해서 다양한입장과 시각을 반영하기 위해서 학제 간접근과 다양한 집단이나 단체의 참여가 필요하다. 또한 첨단 생명과학연구는 인간의 생명보호와 직결되고 인간의 존엄과 가치라는 헌법적 가치보호와 관련성을 가지고 있기 때문에 신중한 승인여부를 결정하는 심사기구가 필요하며, 허가되어 연구가 가능하더라도 엄격한 절차의 적법성을 준수할 것을 요구한다. 이에 대한 절 차요건을 명시하고 사후 관리와 점검체계를 규범 내지 각종 지침으로 제시해 주는 기구로서의 기능을 해야 할 필요가 있다. 그리고 무엇보다 윤리위원회 는 위원회 구성, 절차 및 의사결정에 있어서 정치적 · 제도적 영향과 관련 산 업계의 영향으로부터 독립성을 유지하여야 하며, 생명윤리에 대한 정책결정자 및 일반대중에 대한 교육, 훈련 및 정보제공과 함께 누구든지 참여가 가능한 공개된 대중토론의 장을 마련하는 것도 위원회가 해야 할 역할인 것이다. There is no question that biotechnological developments have been, and can be, of great benefit to humankind in increasing life expectancy and improving the quality of life. And we convinced that moral sensibility and ethical reflection should be an integral part of the process of scientific and technological developments and bioethics should play a predominant role in the choices that need to be made concerning issues arising from such developments. In Korea, there is a National Bioethics Committee, responsible to the President, whose function it is to review policies concerning national bioethics and biosafety in the life sciences and biotechnologies. The Committee will be composed of between 16 and 21 persons, including one Chairperson and one Vice-Chairperson. Membership in the Committee shall be as follows. 1.The following ministers will all be members of the Committee: the Minister of Education and Human Resources Development, the Minister of Justice, the Minister of Science and Technology, the Minister of Commerce, the Minister of Industry and Energy, the Minister of Health and Welfare, the Minister of Gender Equality, and the Minister of Government Legislation. 2.The president will appoint not more than seven representatives of the academic, scientific, and industrial spheres, each of whom have professional knowledge and experience in the fields of life science or medical science. 3.The president will appoint not more than seven representatives of the fields of religion, philosophy, ethics, social science, law, NGO groups, or gender equality. During three years there are several points in the management of the Committee. Above all, the Committee shall be prominent representatives of the scientific, medical, theological, philosophical, social, legal, ecological and economic worlds. The members of the Committee's members shall belong not to the government with the exception of the Minister of Education and Science and Technology and the Minister of Health and Welfare and Family. And the Committee shall be established as a national forum for dialogue on ethical issues in the life sciences. The Committee shall be the central organ for interdisciplinary discourse between the natural sciences, medicine, theology and philosophy, and the social and legal sciences. It shall organize the social and political debate and ensure that all the relevant groups are involved. It shall provide citizens with information and material for discussion (e.g. exhibitions, publications, Internet forums, etc.). The Committee shall express views on ethical issues relating to new developments in the field of the life sciences and on their consequences for the individual and society. The Committee shall submit recommendations for political and legislative action. The Committee shall work together with the national ethics committees and comparable institutions of other States.