지연성으로 발생한 외상성 횡격막 파열의 임상적 고찰

이정희,서홍주,이석기 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Background: Diaphragmatic rupture may occur from blunt or penetrating thoracoabdominal trauma, which may be undiagnosed initially in the acute trauma, work-up and may remain unrecognized. Delayed traumatic diaphragmatic rupture is reported with increasing frequency and is associated with high morbidity and mortality. The purpose of this study was to present our experience and found out early diagnostic method, clinical presentation and management. Matehals and Methods: From March 1998 to February 2004, the 6 patients of delayed diaphragmatic rupture in our hospital were operated. We reviewed the diagnostic interval, symptom, diagnostic method, operative method and complication. Resutt: They were 3 men and 3 women. Mean age was 56.8:t15.8 years(range 29-69). Most common symptom was dyspnea. Delayed diaphragmatic rupture was right-sided in 4 patients, left-sided in 2. The average operative interval of delayed diaphragmatic rupture was 18.8 months(range 5-48). The diagnosis was chest x-ray and thoracic CT. Operative approach were only thorax in 4 patients and both thorax and abdomen in 2. Postoperative complication were observed in 4 patients, and the overall mortality was none. Conclusion: The delayed case of traumatic diaphragmatic rupture tends to be overlooked without suspicion, In all patients with thoracoabdominal blunt injury a rupture of the diaphragm must be suspected. With a high suspicion, a thorough physical examination and diagnostic method is recommended in order to avoid early or late complications.

農家副業으로서의 畜産現況과 그 改善方案에 關한 硏究

洪鐘旭,李熙碩,朴恒均,崔源弼,李鉉凡,金祥基 慶北大學校 1978 論文集 Vol.25-26 No.-

Recently, there have been much corncerns about the strategies which can reasonably increase farm income at the average farm level. In other words, as a result of third-term Five Year Economic Development Plan there was a remarkable gap between farm household and non-farm household incomes. Therefore, various policy tasks to eliminate this unbalanced income growth are currently being implemented. This study was carried out to identify the situation of livestock farming at general farm level, regarded as one of income generation strategies for the farm sector. Some results of the study can be summarized as follows: First of all, it was found that a group of farms which raise a small size of animals like Korean cattle, hog, and various poultry gave higher resource bases as compared with that of non-livestock farms. Secondly, it was also recognized that both farm and farm household income levels of small-scale livestock farms were higher than those of non-livestock farm group within the same region, specifically as much as approximately ￦200,000. Thirdly, it was known that the average size of animal raising per household in 0.9 head of cattle, 0.8 head of hog, and 34 lyers of poultry, respectively. To the end, according to the farm disposal practices of major by-products, only about 18 percent of total rice straws produced at individual farms was utilized for the animal raising, and about 45 percent of all the brans available at farms for the livestock enterprise. The rest of straw and brans in regarded as selling at farm level. In this respect, it may be recommended either to increase current size of animals or to expand number of livestock farms.

체육적 민속놀이의 유형분류

홍장표,임희용,이재학 龍仁大學校 武道硏究所 1998 武道硏究所誌 Vol.9 No.1

This study is aimed at finding a possibility to make folk game developed as the traditional physical education by classifying folk game types in terms of the physical education on the basis of preceding studies and literatures, and preparing the foundation of a physical education historical study of folk games. To let folk games and the physical education approached, folk games was generally classified by realms of amusements and military sports, and a realm of a physical education historical study by amusements and military. Amusements were classified by united games/groups/individuals, and martial arts by military sports/martial arts. S study on united games out of amusements in the physical education history is extremely poor. A study on traditional physical exercises conforming to the purpose not only for the individual harmony of group lives but also for the harmony and combination of groups out of targets of physical education activities intended by the modern physical education is required, and most individual amusements are in the brink of disappearing due to the mechanical civilization these days. In the end, a study on traditional games in the physical education history may form a new game culture required by the modern society, and so their restoration as one of life physical educations is urgently required. A study realm of military arts was classified by military sports martial arts, the physical education historical study for development courses/forms/methods of traditional/drilling military arts is required. Such a traditional/drilling study still be the important data to find the intrinsic meaning of martial arts. However most studies are performed on the center of martial arts converted into now sport events.

장기투석을 받은 만성 신부전 환자에서 발생한 종양에 관한 고찰

황정화,이혜경,홍현숙,박재성,김대호,권귀향,최득린,황승덕,이희발 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.2

The authors tried to evaluate tumor occurrence in long-term dialysis patients with chronic renal failure. Among 359 patients, 20 patients (about 5.6%) were diagnosed with malignancy during long-term dialysis from the period of 1983 to 1995 at our nephrology department. The ultrasonographic and computed tomographic findings including the clinical features of 20 patients that were retrospectively reviewed. The mean age of the patients was 53 (37-75)years old and the ratio of male to female was 9:1. Among the 20 cases, 7 cases of hepatoma (35%) were developed. Among them, urinary tract tumors such as renal and bladder cancer were developed in 4 (20%) and 2 (10%) of the cases. Other malignant tumors were lymphoma, stomach cancer, uterine cervical cancer, cholangiocarcinoma, lung cancer, meningioma, and acoustic neuroma one case of each (each of 5.3%). The most common tumor in patients with chronic renal failure, who were receiving long-term dialysis, was hepatoma and the second most common tumor was cancer of the urinary tract such as kidney and bladder.

西部慶南에서 發生한 소의 GLOBIDIUM病에 關한 報告

馬点述,박응복,李熙碩,文武洪 진주농과대학 1969 진주농과대학 연구논문집 Vol.- No.8

이번에 慶南 山淸郡에서 調査한 Globidium病發症牛 3例의 觀察에서 다음과 같은 結果를 얻었다. (1) 從來의 全南道 南部海岸地方의 本病發生地域 以外에 西部慶南에서도 Globidium病의 發生이 確認되었다. (2) 重症例에서 皮膚內의 原蟲胞囊의 分布密度는 매우 稠密하고 全身皮膚는 한점 남김없이 胞囊에 占據되어 있어 臨床的으로 瀕死期에 이룬 重態이었다. (3) 臟器, 組織別 胞囊의 分布는 皮膚上皮組織內, 眞皮層, 皮下骨格筋, 口唇腺 및 體淺部淋巴節에 있었다. (4) 皮膚외의 藏器의 組織學的所見은 口唇腺組織의 慢性增殖性炎, 骨格筋의 Zenker氏變性 및 體表淋巴節의 慢性淋巴節炎 이었다. Globiodiosis, cyst-forming protozoan disease which occur in South Africa, Sudan, France, Iberian Peninsula, Mexico and Korea, has been reported as an endemic skin disease in southern coast district of Cholranam-do, Korea. In the course of systemic examination of cattles in western Kyongsangnam-do showing thickend, rugous skin lesion during September, 1968, three cases of bovine Globiodiosis were observed. And in histological examination of the skin and other organs, we found characteristic globidial cysts of about 380-470μin diameter, composed of a thick wall of homogenous, pale blue staining substance lined on its inner surface by a thin ring of cytoplasm which contains two or eight large nuclei and with its inner contents, tiny crescentic bodies. And so, on the pathological studies of these globidial patients some findings were summerized as follows: 1. One of the affected patients exhibited extreme emaciation caused by cachexic condition with dispnea, oculonasal discharge, progressive scleroderma, thickening and fissuring of the skin and a alopecia representing umerous globidial cysts, present on any area of the whole skin. 2. The globidial cysts were distributed through the squamous epithelium of the skin, the dermal layer, the cutaneous skeletal muscle, the labial gland, and the superficial lymphnodes of the body. 3. Histopathological entity of the involved organs was characterized by chronic hyperplastic inflamation in the labial gland, Zenker's degeneration of the skeletal muscle and chronic lymphadenitis accompanying with diffuse reticular cell hyperplasia, multiple focal proliferation of plasma cells and macrophages in the medulally cords, and occupation with reticular cells macrophages and erythrocytes in the distend sinuses.

한국 비만 여성의 신체 계측에 의한 체지방 추정

심경원,김지연,서희선,이홍수,이상화,강지현 대한비만학회 2002 The Korean journal of obesity Vol.11 No.2

연구배경 : 국내 비만 여성을 대상으로 비용이 적게 들고 단순하면서도 보다 정확하게 체지방률을 추정할 수 있는 체지방률 추정식을 작성함으로써 쉽게 체지방률과 조절해야하는 지방의 양을 판단할 수 있도록 하고자 한다. 방법 : 이대목동병원 비만클리닉을 처음으로 내원한 19세 이상의 성인 여자 607명 중 체질량지수가 25 kg/㎡ 이상인 500명을 연구대상으로 하여 목, 가슴, 허리, 엉덩이, 대퇴, 하퇴, 발목, 상완, 전완, 손목의 10부위의 둘레와 생체전기저항분석법 (bioelectrical impedance analysis, BIA) 방식의 체성분 분석기를 이용하여 체지방률을 측정하였다. 체지방률 추정식을 구하기 위해 BIA에 의한 체지방률을 종속변수로 하고 , 신체 둘레 계측기 및 신장, 체중, 체질량지수, 연령을 독립변수로 하여 단계별 다중회귀분석 (multiple stepwise regression)을 시행하였다. 결과 : 신장과 체중, 연령, 체질량지수 및 신체 둘레 측정치 중 체지방률을 반영하는 지표는 체질량 지수, 전완둘레, 신장, 엉덩이 둘레, 하퇴둘레였고, 이 다섯가지 지표를 이용한 체지방률 추정식은 66.1%의 예측력과 2.86%의 측정 오차를 나타냈다 (R^2=0.661, SEE=2.86). 결론 : 비만한 성인 여성에서 신장과 체중, 연령 및 신체 둘레 계측치를 이용한 본 연구의 추정식은 체지방률(%)을 적은 오차범위로 비교적 정확하게 반영하였다. Background : This study was conducted to develop a regression equation that accurately estimates body fat percentage using relatively easy and inexpensive method in adult obese Korean women. Method : Data were collected among 500 obese Korean women visiting obesity clinic in Ewha woman's university Mokdong hospital, Seoul, Korea. Height, weight, and circumferences at ten body sites (neck, chest, waist, hip, thigh, calf, ankle, arm, forearm, wrist) were measured s well as total body bioelectrical impedance. Results : The full regression equation estimates body fat percentage included six variables : BMI, forearm circumference, height, hip circumference, thigh circumference. This equation accounted for 66.1% of the variance in body weight measured by bioelectrical impedance, and their standard error of estimate was 2.86%. Conclusion : For the obese Korean women in this study, circumference measurements provided a s relatively good estimation of body fat percentage.

우리나라 大豆 獎勵 普及品種의 退化程度와 그의 生産性에 関한 硏究

Hong Suk Lee(李弘䄷,),Eiu Ho Park(朴義浩),Eun Hi Hong(洪殷惠) 한국육종학회 1983 한국육종학회지 Vol.15 No.2

Fifty five lines of six recommended soybean varieties, which were produced in different regions and cultivated for different number of years after released as farmer’s seed were collected. They were evaluated for the genetic, pathological and ecological degeneration by testing the seed contamination, infection to disease and germination and for its effects on grain yield. Most of the farmer’s seeds collected were subjected to the degeneration, showing the higher rates of SMV infection and seed contamination and the decrease in the seed weight. Bongeui, Dongbuktae, Jangyeupkong and Hill tended to be poorer in yield performances with the year of farmer’s home seed-raising. Depending on the varieties, the grain yield was observed to be closely related to the SMV infection rate and the 100-grain weight in the next generation of collected farmer’s seed, and SMV infection rate was also found to be correlated with the seed contamination rate and the 100-grain weight in the next generation of collected farmer’s seed.

Continentalic Acid Rather Than Kaurenoic Acid Is Responsible for the Anti-Arthritic Activity of Manchurian Spikenard In Vitro and In Vivo

Hong, Riwon,Kim, Kyoung Soo,Choi, Gwang Muk,Yeom, Mijung,Lee, Bombi,Lee, Sanghyun,Kang, Ki Sung,Lee, Hyang Sook,Park, Hi-Joon,Hahm, Dae-Hyun MDPI AG 2019 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.20 No.21

<P>The aim of this study was to identify the active compound responsible for the pharmacological activities of Manchurian spikenard (Aralia continentalis Kitag.). Interleukin (IL)-1β-stimulated human chondrocytes and monoiodoacetate (MIA)-induced osteoarthritic rats were treated with the 50% ethanolic extract of spikenard or its major components, such as continentalic acid (ent-pimara-8(14),15-diene-19-oic acid) and kaurenoic acid (ent-kaura-16-en-19-oic acid). The spikenard extract significantly inhibited IL-1β-stimulated production of IL-6, IL-8, metalloproteinase (MMP)-1, MMP-13, cyclooxygenase (COX)-2, inducible nitric oxide synthase (iNOS) and prostaglandin(PG)E2 in a dose-dependent manner but not MMP-3 production. The extract also inhibited the IL-1β-induced translocation of NF-κB/p65 into the nucleus and dose-dependent phosphorylation levels of extracellular signal-regulated kinase (ERK), Jun amino-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase. Continentalic acid exhibited significant anti-arthritic activity corresponding exactly to that of the extract containing an equivalent amount of continentalic acid. On the other hand, kaurenoic acid exhibited a compatible activity at about a 10-times higher molar concentration than that of continentalic acid. In vitro anti-arthritic activities of the spikenard extract and continentalic acid were also confirmed in MIA-induced osteoarthritic rats. The 50% ethanolic extract of Manchurian spikenard exhibited promising anti-arthritic activities in the in vitro and in vivo osteoarthritis models, and continentalic acid, not kaurenoic acid, was most probably responsible for those activities.</P>

Human bone marrow-derived mesenchymal stem cell gene expression patterns vary with culture conditions

Lee, Myoung Woo,Kim, Dae Seong,Yoo, Keon Hee,Kim, Hye Ryung,Jang, In Keun,Lee, Ji Hyang,Kim, So Yeon,Son, Meong Hi,Lee, Soo Hyun,Jung, Hye Lim,Sung, Ki Woong,Koo, Hong Hoe Korean Society of Hematology; Korean Society of Bl 2013 Blood Research Vol.48 No.2

<P><B>Background</B></P><P>Because of the heterogeneity of human mesenchymal stem cells (MSCs), methods for cell expansion in culture and the effects on gene expression are critical factors that need to be standardized for preparing MSCs. We investigated gene expression patterns of MSCs with different seeding densities and culture times.</P><P><B>Methods</B></P><P>Bone marrow-derived MSCs were plated at densities from 200 cells/cm<SUP>2</SUP> to 5,000 cells/cm<SUP>2</SUP>, and the gene expression patterns were evaluated over time using a reverse-transcription polymerase chain reaction assay.</P><P><B>Results</B></P><P>The mRNA levels of factors that play a critical role in cell migration and tissue regeneration, such as podocalyxin-like protein (PODXL), α4-integrin, α6-integrin, and leukemia inhibitory factor (LIF), were higher in MSCs plated at 200 cells/cm<SUP>2</SUP> than in MSCs plated at 5,000 cells/cm<SUP>2</SUP>. The mRNA levels of these factors gradually increased for 10 days and then decreased by day 15 in culture. MSCs seeded at 200 cells/cm<SUP>2</SUP> that were cultured for 10 days expressed high levels of Oct-4 and Nanog. Indoleamine 2,3-dioxygenase, cyclooxygenase-1, and hepatocyte growth factor expression were upregulated in the presence of the proinflammatory cytokine interferon-γ in these cells.</P><P><B>Conclusion</B></P><P>We found differences in the gene expression patterns of MSCs under different culture conditions. MSCs from 10-day cultures seeded at a low density were efficiently expanded, expressed PODXL, α6-integrin, α4-integrin, and LIF, and maintained properties like stemness and immunomodulation. Therefore, <I>ex vivo</I> expansion of MSCs maintained for an adequate culture time after plating at low cell density can provide an effective regenerative medicinal strategy for cell therapies using MSCs.</P>

Use of Random Amplified Polymorphic DNAs for Linkage Group Analysis in Interspecific Hybrid F₂ Generation of Cucurbita

Lee Yun Hi(이윤희),Jeon Hong Jeong(전홍정),Hong Kue Hyon(홍규헌),Kim Byung Dong(김병동) 한국원예학회 1995 Horticulture, Environment, and Biotechnology Vol.36 No.3