만성 간질환에 대한 DDB(Biphenyl Dimethyl Dicaboxylate)의 임상적 효과

이헌영,임의혁,김성걸,김진희,육은주,성자원,김병호,정형용,강대영,김영건 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

To investigate the effects of short-term administration of DDB(Biphenyl Dimethyl Dicarboxylate) for decreasing elevated serum aminotransferase levels in chronic liver diseases, authors applied 3 capsules of DDB per day at each meal time for 35 patients and compared with 35 patients treated with other conservative management. The following results were obtained. 1. Serum alanine aminotransferase (ALT) levels significantly decreased from 247.1± 180.0 IU/L of pretreatment level to 96.6±126.0 IU/L, 61.1±62.7 IU/L and 38.0±26.8 IU/L after 1, 3 and 6 months of treatment(p<0.05) and effective rates were observed in 60.0%, 71.4% and 88.6% of patients after 1, 3 and 6 months of treatment. 2. Serum aspartate aminotransferase (AST) levels decreased also significantly from 167.8±96.9 IU/L of pretreatment levels to 124.4±155.0 IU/L, 77.9±49.6 IU/L, 60.6± 46.9 IU/L after 1, 3 and 6 months of treatment(p<0.05), but decreasing pattern of serum AST was less significant than that of serum ALT. 3. No significant difference were observed in the serum ALT and AST changes according to the cause and duration of hepatitis. 4. No significant adverse effects were observed in whole patients treated with DDB. It is suggested that small dose administration of DDB is effective for decreasing serum aminotrans ferase levels in chronic liver disease in which other conservative management was not effective.

유치열과 영구치열의 구개 각부의 관계에 대한 연구

이용훈,백병주,양연미,이용희,김상훈,김재곤 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.4

본 연구는 유치열과 영구치열에서 구개의 길이, 폭, 깊이 및 치열궁의 형태 등을 조사하여 남녀간의 차이와 유치열과 영구치열간의 변화양상을 파악하는 것이다. 유치열기 아동 100명과 영구치열기 성인 100명 총 200명을 대상으로 하여 상악 석고 모형을 채득하고 3차원 laser scanner(SD Scanner, DS4060, LDI, U.S.A.)를 통한 석고 모델의 측정을 통해 cloud data, polygonization, section curve and loft surface, fit and horizontal plane (Surfacer 10.0, Imageware, U.S.A.)을 기초로 하여 구개의 폭, 길이, 높이 및 치열궁의 형태 등을 계측하였다. 통계학적 분석을 위해 t-tests가 사용되었다. 이에 다음과 같은 결론을 얻었다. 1. 구개의 계측항목에서 유치열 전방부 구개높이를 제외한 나머지 항목에서 남자가 여자보다 크게 나왔으며, 유치열은 전구개폭(p<0.05)과 후구개폭(p<0.01), 영구치열은 구개폭(p<0.05)과 전구개길이(p<0.01), 중구개, 후구개길이(p<0.05)에서 남녀간에 유의한 차이가 있었다. 2. 남녀의 구개지수에서 유치열에서는 구개장고지수(p<0.05)와 구개장폭지수(p<0.01)가 남녀간에 통계학적으로 유의한 차이가 있었다. 영구치열의 구개지수에서는 남녀간에 유의한 차이가 없었다. 3. 유치열과 영구치열의 계측항목 비교에서 후방부 구개폭이 가장 많이 증가하였으며, 다음으로 후방부 구개높이, 전방부 구개폭, 전방부 구개길이 순이었다. 전방부 구개높이와 후방부 구개길이는 오히려 감소하였다. 4. 유치열과 영구치열의 구개지수 비교에서 구개장고지수와 구개장폭지수, 후구개폭고지수는 영구치열에서 증가하였고, 나머지 지수는 감소하였다. The purpose of this study was to clarify the palatal arch length, width and height in the primary and permanent dentition. Samples were consisted of normal occlusions both in the primary dentition(50 males and 50 females) and in the permanent dentition(50 males and 50 females). With their upper plaster casts were used and through 3-dimensional laser scanning(3D Scanner, DS4060, LDI, U.S.A.), cloud data, polygonization, section curve and loft surface, fit and horizontal plane were based to measure the palatal arch length, width and height(Surfacer 10.0, Imageware, U.S.A.). T-tests were applied for the statistical analyze of the data. The results were as follows : 1. In the measurement values, the values of the male were higher than those of the female except primary anterior palatal height. There were not only statistically significant differences in anterior palatal width(p<0.05) and posterior palatal width(p<0.01) in primary dentition but palatal width(p<0.05), anterior palatal length(p<0.01), middle and posterior palatal length(p<0.05) in permanent dentition between male and female. 2. In the indices of palate, there were statistically significant differences in height-length index(p<0.05) and width-length index(p<0.01) between male and female in primary dentition. In permanent dentition, there was statistically difference between male and female. 3. In the measurement values, posterior palatal width was increased most greatly. Posterior palatal height, anterior palatal width and anterior palatal length were followed by descending order. On the other hand, anterior palatal height and posterior palatal length were decreased. 4. In the indices of palate, the height-length index, the width-length index and posterior height-width index were increased, but the others were decreased.

매복 견치 및 저위교합 제 1대구치의 자가 이식에 의한 치험례

이승익,김재곤,권선자,백병주 大韓小兒齒科學會 1995 大韓小兒齒科學會誌 Vol.22 No.2

In orthodontic treatment of certain cases of tooth loss, aplasia, or ectopia, autotransplantation is sometimes valid treatment alternative often provides and improved result, compared to conventional orthodontic treatment, an apprporiate donor tooth is available and the anatomic circumstances permit it. Clinically, successful transplants must show a radiolucent space between the roots and surroundings bone. There must be no evidence of ankylosis, no permanent root resorption, and no inflammation. Histologically, the criterion of success is a normal and functional periodontal ligament between the root surfaces of transplants and the bone, or gingival connective tissues. The successful autotransplantation of a impacted maxillary canine and infraoccluded mandibular 1st molar is reported. In case Ⅰ, impacted canine with incompletely developed root apex was maintained pulp vitality due to appropriate root development and short extraoral time, atraumatic surgical procedure. In case Ⅱ, infraoccluded molar was started endodontic treatment after 3 weeks. Because of closed apex, possibility of revasculization is rare. Both case Ⅰ, Ⅱ did not ankylosis and the periodontal and periapical tissues appears to be normal after 3 months. In autotransplantation cases it is important to transplant the tooth as quickly and as atraumatically as possible to dimish the chance of ankylosis and root resorption. In all cases of transplantation, patient selection minimal operating time, and good oral hygine will increase the chance for a successful prognosis.

법랑질과 복합레진 접착부의 피로파괴에 관한 실험적 연구

이영수,김재곤,백병주 의치학사 1994 치과임상 Vol.14 No.12

This study was to evaluate the tensile bond strength and fatigue life of composite bond to enamel surface. Three kinds of composite resin restorative materials including Prisms AP. H., Clearfil Photo-Posterior, and Z 100 were used for this study. Fatigue test was conducted under peak cyclic flexural stresses fo 5.98kg/mm' and 5.42kg/md using the electro-dynamic type fatigue testing machine. The obtained results were as follows : 1. Tensile bond strengths were 1.686 0.653kg/mm' at Z100, 1.637 0.634kg/md at Prisma AP. H, and 1.584 0.361kg/mm' at Clearfil Photo-Posterior, but didn't show a significant difference (P>0.05). 2. Average fatigue life were 470,739 388,181 cycle at Z100, 195,010 306,921 cycle at Prisma AP. H, and 33, 219 93,756 cycle at Clearfil Photo-Posteiro under constant fatigue stress of 5.98kg/mm', and Z100 was significant difference with Clearfil Photo Posteior(P<0.05). 3. Among the mode of failure for the specimens, most of failure was adhesive failure and mode of failuer for Z100 was throughly distributed, but mode of failure of Clearfil Photo-Posterior was entirely adhesive failure.

CARIES-METER를 이용한 치아우식 치료법의 기준에 관한 고찰

이지연,정홍주,백병주 全北大學校 齒醫學硏究所 1991 전북치대논문집 Vol.9 No.1

The purpose of this study was finding of criteria for exact diagnosis of initial caries and advanced caries lesions. 57 primary molar teeth & 43 permanent first molar teeth of 75 children that visited pedodontic department of chonbuk National University hospital were used for experiment. We compared with radiographic examination and suitable clinical treatment according to the extent of dental caries by using Caries Meter L. The obtained results were as follows. l. Concerning of the equality rate in the primary molars and permanent teeth, the case of comparing radiographic examination and clinical treatment method in the highest rate as 98.24% in the primary molars, whereas the case of comparing Caries Meter L and clinical treatment is the highest rate as 90.7% in the permanent teeth. 2. When comparing of the measurement in Caries Meter L and radiographic examination of primary molars, the concurrent rate on extent of dental caries was 100% in the enamel, 78% in the dentin and 50% in the pulp, the Pearson Correlation was r=0.864 and there were significant difference statistically as significant level α=0.01(P<0.01). 3. When comparing of the measurement in Caries Meter L and clinical treatment method of primary molars, the concurrent rate on extent of dental caries was 100% in the enamel, 80% in the dentin and 55.6% in the pulp, the Pearson Correlation was r=0.877 and there were significant difference statistically as significant level α= 0.01(P<0.01). 4. When comparing of the radiographic examination and clinical treatment method of primary molars, the concurrent rate was high as 90% in the pulp, the Pearson Correlation was r=0.982 and there were significant difference statistically as significant level α= 0.01(P<0.01). 5. When comparing of the measurement in Caries Meter L and radiographic examination of permanent teeth, the concurrent rate was 78% in the enamel, 66.7% in the dentin and 100% in the pulp, the Pearson Correlation was r=0.689 and there were significant difference statistically as significant level α=0.01(P<0.01). 6. When comparing of the measurement in Caries Meter L and clinical treatment method in the permanent teeth, the concurrent rate was 95.2% in the enamel, 85.7% in the dentin and 50% in the pulp, the Pearson Correlation was r=0.930 and there were significant difference statistically as significant level α=0.01(P<0.01). 7. When comparing of the radiographic examination and clinical treatment method in the permanent teeth, the concurrent rate was 74.1% in the enamel, 57.1% in the dentin and 50% in the pulp, the Pearson Correlation was r=0.681 and there were significant difference statistically as significant level α= 0.01(P<0.01).

정전 열 접합을 이용한 Multi-Substrate Bonding

이덕중,주병권,최우범,한정인,조경익,이광배,장진,오명환 경북대학교 센서기술연구소 1997 센서技術學術大會論文集 Vol.8 No.1

We performed silicon-to-glass bonding using silicon direct bonding followed by anodic bonding(SDAB). Initial bonding between glass and silicon was caused by the hydrophilic surfaces of silicon and glass ensemble using silicon direct bonding(SDB) method. We found that the bonded specimen using SDAB process had higher strength than one using anodic bonding process only. We performed multiple layer bonding by SDAB, which is glass- silicon -glass as sandwich structure. In the silicon wafer, the (1mm x 2mm x 500μm)-sized cavity was formed by the anisotropic etching of the silicon substrate in EPW(Ethylendiamin-Pyrocatechol-Water). And, the cavity was sealed with glass wafers by SDAB method.

동부 F_2 世代에 있어서 莢柄長, 莢長 및 莢當粒數에 관한 遺傳分析

李秉主,張權烈,金鎭馨 慶尙大學校 1985 論文集 Vol.24 No.1

This experimental studies were conducted to clarify the effects of selection, and aimed at estimating genetic parameters such as, gene action, combining ability and heritability on three agronomic characters in Cowpea (Vigna sinensis Savi.). The six different parents and 15 F_2 hybrids by 6×6 diallel crosses were used as materials, and were planted in a randomized block design with three replications. The results obtained are summarized as follows : 1. Vr-Wr graphic analyses Length of pod stalk was found to be inherited in over dominance. and length of pod and seed numbers per pod were inherited in partial dominance. 2. Components of variance: Estimates of additive components of variances were greater than those of dominance components of variances for length of pod and seed numbers per pod. Negative values of F were estimated for two characters, length of pod and seed numbers per pod. The highest heritability value was found in length of pod, but the value of seed numbers per Pod was the lowest. 3. Combining ability analyses: The mean squares of general combining ability for length of pod and seed numbers per pod were higher than those of specific combining ability. 4. Effects of combining ability: The high GCA effects were expressed by variety TVu1857 in length of pod stalk and seed numbers per pod, variety TVu2885 in length of pod. The high SCA effects were exhibited in the hybrids between TVu1857×J78 and TVu2885×J80 in length of pod stalk and seed numbers per pod, TVu1857×TVu2885 and TVu2734×TVu2885 in length of pod. Therefore, it can be concluded that TVu lines could be the useful varieties in cowpea breeding for long pod and high yielding.

집단 따돌림 피해학생을 대상으로 한 인지행동적 집단치료 개발을 위한 예비 연구

이주현,신지용,연병길,한창환 대한소아청소년정신의학회 2000 소아청소년정신의학 Vol.11 No.2

본 연구는 집단 따돌림 피해학생을 대상으로 시행한 인지행동적 집단치료의 개발을 위한 예비 연구이다. 정상적인 중학교 1학년 학생 202명에게 도덕발달수준척도, 오퍼 자아상척도, 우울 및 상태ㆍ특성불안척도의 분포와 상관관계를 조사하였다. 자아상과 우울, 불안은 서로 강한 상관관계를 보였으나, 도덕발달과는 상관관계를 보이지 않았다. 이는 도덕발달이 정서에 크게 영향받지 않고 인지 발달적 과정에 의존하는 것을 시사한다. 그리고 교사의 관찰에 의해 집단 따돌림 피해를 받으면서 학교 적용에 어려움을 보이는 중학교 1학년 학생 5명의 도덕발달수준척도, 오퍼 자아상척도, 우울 및 상태ㆍ특성불안척도는 전체 집단과 유의한 차이를 보이지 않았다. 이 피해학생들을 대상으로 12회에 걸쳐 인지적 집단 정신치료를 시행하고, 치료 전후에 상기 4가지 척도의 변화를 평가하여 효용성을 검정하였으나 통계학적으로 유의한 변화는 없었다. 그러나 참가 학생들이 치료 기간 중에 기재한 일기에서 확인되는 심리적 마음자세(psychological mindedness)의 향상과 담임 교사의 긍정적인 평가보고는 의미있는 것으로 생각되었다. 중심 단어 : 집단 따돌림ㆍ인지행동적 집단치료ㆍ청소년ㆍ자아상ㆍ도덕발달ㆍ우울ㆍ불안 Bullying is the intentional, unprovoked abuse of power by one or more children to inflict pain on or cause distress to another child on repented occasions. Bullying can be considered to be a form of child abuse : peer abuse. Victims suffer adverse effects in the short and long term. If bullying is regarded as a form of abuse then professionals have a duty to detect it, take it seriously, and ensure that it is deal with to reduce the child's suffering and minimize the potential long term effects. This study is aimed preliminarily the development of cognitive behavioral group therapy for school bullied. 202 normal middle school freshman responded to self report scales-Offer's Self-Image Questionnaire-Revised, Children's Depression Inventory, Spielberger State/Trait Anxiety scale, and Defining Issues Test. The data were analyzed with Pearson's correlation to test the relationship among the above 4 variables. Self Image, depression, and anxiety were correlated strongly each other. But moral development was not correlated with self image, depression, and anxiety. Five school bullied students were referred by their teacher for school maladjustment. The author tried 12 sessions of Cognitive-Behavioral group therapy and assessed their behaviors pre- and post intervention by above 4 scales. There were no significant different intervention effects statistically. But It is meaningful that improvement of psychological mindedness in diary written by subject in treatment sessions KEY WORDS : School bullyingㆍCognitive-behavioral group therapyㆍAdolescentㆍSelf imageㆍMoral developmentㆍDepressionㆍAnxiety

법랑질 형성 부전증에 대한 증례보고

이승영,백병주,이지연 大韓小兒齒科學會 1994 大韓小兒齒科學會誌 Vol.21 No.1

Amelogenesis imperfecta(AI) is defined as a genetically determined effect affecting enaml formation and may be associated with other ectodermal or systemic disorders. It is entriely an ectodermal disturbance, since the mesodermal components of the teeth are basically normal. The presentation of diverse clinical manifestations in thought to result from the heterogeneous structural and chemical defects. The anomaly occurs in the general population in the range of 1 n 14,000 to 16,000, to 1.4 in 1000, depending on the specific population studied. Classification of the AI types considers mode of inheritance and clinical manifestations. The most widely accepted classifi-cation system recognizes three major groups ; i.e., hypoplastic(thin enamel), hypocalcified (primary mineralization defect), hypomaturation(defect in enamel maturation). Delineationg speific AL types can be confusing given the phenotypical similarity of many forms and that the most recent classification lists 14 different AI types. A 8-years-old female patient with complaint of abnoraml crown shape and discoloration of maxillary anterior tooth and excessice wear of posterior dentition of both arch.came to Dept.of pedodontics, College of Dentistry, Chonbut National University for rahabilitation. The treatment depends on its severity and the demands of esthetic improvement. In this case, resin veneer crown of maxillary anteiror tooth and composite resin restoration of mandibular anterior tooth showed good esthetic result. Restoration of Mx. and Mn. 1st first molar with stainless steel crown rehabilitated the masticatory function and estabilished the vertical dimension of occlusion. But futher care is needed for estabilishment of final vertical dimension of occlusion after completion of permanent dentition.

Thermal cycling 과 시효처리가 Glass-Ionomer수복재의 인장강도에 미치는 영향

이승익,백병주,김재곤,이승영,김문현 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.4

본 연구에서는 구강환경과 유사한 액상의 조건하에서의 온도변화가 광중합형 글래스아이오노머계 수복재의 인장강도에 미치는 영향을 평가하기 위해 대조군으로 2종의 재래형 glass ionomer를 선택하고 실험군으로 2종의 광중합형의 resin-modified glass ionomer와 2종의 polyacid-modified resin composite을 선택한 다음 수중에서의 thermal cycling과 시효처리를 행하였으며, 다음과 같은 결론을 얻었다. 1. 글래스아이오노머 수복재의 인장강도를 측정한 결과, polyacid-modified resin composite, resin-modified glass ionomer 그리고 재래형 glass ionomer의 순으로 나타났다. 2. 인장강도는 30일간의 시효처리로 증가되는 경향을 보였다. 3. 재래형 glass ionomer 수복재의 인장강도는 thermal cycling 처리로 증가되는 경향을 보였으며, 37℃의 증류수 중에 1시간 침적한 군과 10,000회의 thermal cycling을 비교한 결과 유의한 차이로서 강도의 증가를 나타냈다(P<0.01). 4. thermal cycling 군의 인장강도는 DR군이 45.4MPa로 최대치를, FL군이 13.4MPa로 최소치를 나타냈으며, 각 군간의 통계적 유의성을 검증한 결과 polyacid-modified resin composite의 인장강도가 나머지 군과 유의한 차이를 보였다(p<0.05). 5. 특성강도는 DR군이 48.6MPa로 가장 높은 강도치를 보였으나, Weibull 계수는 CG군이 8.9로 가장 높은 값을 보여 시험재료 중에서 가장 작은 강도의 분산을 나타냈다. This study was performed to evaluate the effect of aging and thermal cycling on the tensile strength of six commercially available glass-ionomer materials: two chemically set glass-ionomer materials(Fuji Ⅱ, fuji Ⅸ), two resin-modified glass-ionomer materials(Fuji Ⅱ LC, Vitremer), and two polyacid-modified composite resins(Compoglass, Dyract). Rectangular tension test specimens were fabricated in a teflon mold giving 5mm in gauge length and 2mm in thickness. All samples were divided into 3 groups. Group 1 was immersed in a 37℃ distilled water for 1 hour. Group 2 was immersed in a 37℃ distilled water for 30 days. Group 3 was subjected to 10,000 thermal cycles between 5℃ and 55℃, and the immersion time in each bath was 15 seconds per cycle. Tensile testing was carried out at a cross-head speed of 0.5mm/min and fracture surfaces were examined with scanning electron microscope. The results obtained were summarized as follows; 1. The polyacid-modified composite resins were stronger than the resin-modified glass-ionomer materials, which were much stronger than the conventional glass-ionomer materials. 2. Tensile strengths were slightly increased after aging treatments for 30days. 3. Tensile strengths of conventional glass ionomers were significantly increased after thermal cycling treatment(p<0.01). 4. The highest tensile strength value of 45.4MPa was observed in the Dyract group and the lowest value of 13.3MPa was observed in the Fuji Ⅱ LC group after the thermal cycling test, and the strengths of polyacid-modified composite groups were significantly higher than those of other groups. 5. The highest characteristic strength value of 48.6MPa was obtained in the Dyract group, however the highest Weibull modulus value of 8.9MPa was obtained in the Compoglass group after thermal cycling test.