Antiadhesive effect and safety of oxidized regenerated cellulose after thyroidectomy

Kyoung Sik Park,Kyu Eun Lee,Do Hoon Ku,Su-Jin Kim,Won Seo Park2,Hoon Yub Kim3,,Mi Ra Kwon1,Yeo-Kyu Youn1 대한외과학회 2013 Annals of Surgical Treatment and Research(ASRT) Vol.84 No.6

Purpose: To evaluate the antiadhesive effects and safety of an oxidized regenerated cellulose (Interceed) after thyroidectomy. Methods: Seventy-six thyroidectomized patients were prospectively randomized into two groups with regard to the use of Interceed. We evaluated each group for their adhesive symptoms using four subjective and four objective items at the 2nd week, 3rd and 6th month after thyroidectomy. All patients were examined for vocal cord motility by indirect laryngoscope at each period. Results: Total adhesion scores at each postoperative follow-up period decreased with time, but were not significantly different in each group. The median score for swallowing discomfort for liquid was significantly lower in the Interceed group than in the control group 2 weeks after surgery. In addition, the severity of skin adhesion to the trachea was reduced in the Interceed group compared with the control group 6 months after surgery. During the study, there were no adverse effects or significant differences in postoperative complications between the groups. Conclusion: Interceed appeared to be safe and effective in improving neck discomfort at early postoperative periods and preventing skin adhesion to the trachea 6 months after thyroidectomy.

효과적인 유역관리를 위한 CN기법 기반의 침투량 산정 및 기저유출량 분석

김희원 ( Hee Won Kim ),신연주 ( Yeon Ju Sin ),최정헌 ( Jung Heon Choi ),강현우 ( Hyun Woo Kang ),류지철 ( Ji Chul Ryu ),임경재 ( Kyoung Jae Lim ) 한국물환경학회 2011 한국물환경학회지 Vol.27 No.4

Increased Non-permeable areas which have resulted from civilization reduce the volume of groundwater infiltration that is one of the important factors causing water shortage during a dry season. Thus, seeking the efficient method to analyze the volume of groundwater in accurate should be needed to solve water shortage problems. In this study, two different watersheds were selected and precipitation, soil group, and land use were surveyed in a particular year in order to figure out the accuracy of estimated infiltration recharge ratio compared to Web-based Hydrograph Analysis Tool (WHAT), The volume of groundwater was estimated considering Antecedent soil Moisture Condition (AMC) and Curve Number (CN) using Long Term Hydrologic Impact Assessment (L-TH1A) model. The results of this study showed that in the case of Kyoung-an watershed, the volume of both infiltration and baseflow seperated from WHAT was 46.99% in 2006 and 33.68% in 2007 each and in Do-am watershed the volume of both infiltration and baseflow was 33.48% in 2004 and 23.65% in 2005 respectively. L-TFIIA requires only simple data (i.e., land uses, soils, and precipitation) to simulate the accurate volume of groundwater. Therefore, with convenient way of L-TKIA, researchers can manage watershed more effectively than doing it with other models. L-THIA has limitations that it neglects the contributions of snowfall to precipitation. So, to estimate more accurate assessment of the long term hydrological impacts including groundwater with L-THIA, further researches about snowfall data in winter should be considered.

체육교사의 리더십 유형과 고등학생의 체육수업 만족에 관한 연구

김흥태(Heung-Tae Kim),신진원(Jin-Won Shin),최경호(Kyoung-Ho Choi) 한국엔터테인먼트산업학회 2011 한국엔터테인먼트산업학회논문지 Vol.5 No.4

본 연구는 체육교사의 리더십 유형에 따른 고등학생의 체육수업 만족을 규명하는데 목적이 있다. 이 연구의 목적을 규명하기 위하여 경기도 성남시에 소재하고 있는 5개 고등학교 1, 2학년생 500명을 대상으로 편의추출법(convenience sampling)으로 총 487부를 회수하였고, 그 중 442부가 분석에 사용되었으며, SPSS 13.0 Windows 프로그램을 이용하여 타당도와 신뢰도 검증, 빈도분석, t-검증, 그리고 표준중다회귀분석을 실시하여 다음과 같은 결론은 얻었다. 첫째, 일반적 특성에 따른 고등학생의 체육수업 만족은 성별에 따라 교사만족, 사회성함양, 수업용이는 남자가 여자보다 높았고, 수업만족, 수업평가는 여자가 남자 보다 높게 나타났으며, 학년별에 따른 고등학생의 체육수업 만족은 모두 1학년이 2학년보다 높게 나타났다. 둘째, 체육교사의 리더십 유형과 고등학생의 체육수업 만족과의 영향 관계는 긍정적 보상형으로 수업을 할수록 고등학생의 체육수업 만족은 높아지는 것으로 나타났다. 이와 같이 고등학교 체육교사의 리더십과 학생간의 체육수업 만족에 대한 결과를 바탕으로 향후 바람직한 학교체육의 방향을 논의하는 기초적인 자료로써 활용되기를 바란다. This study is aim to define high school students" satisfaction based on the type of leadership in a physical education teacher in high school physical education classes. To investigate this study, we used "convenient sampling" to 500 high school students who are in 1st and 2nd grade in Kyoung-gi-do and recollected 487 copies, and SPSS 13.0 windows program was used for verifying a frequency analysis and reliability analysis, t-test and a standard multiple regression analysis. And they were conducted by all of the following conclusion was obtained. First, in terms of satisfaction on teachers, social propensity and class satisfaction, there is statistical significance that male students have more positive attitude than female students. Female students showed higher satisfaction on the class satisfaction and test method in the physical education class. It showed that the first grade students have higher satisfaction than the second graders according to the grade survey. Second, students" satisfaction became higher and higher when physical education teachers gave more positively reward to them related on their satisfaction and effect in the physical education class. Thus, we hope that this data will be used as a basic data to discuss the direction on the right school physical education between teachers" leadership and students" satisfaction in physical education class.

해군 근무환경에서 노출될 수 있는 염화알루미늄의 피부독성 예방을 위한 보호크림 개발 및 효능평가

박창용(Chang-Yong Park),어원석(Won Souk Eoh),이준원(Joon-Won Lee),오영현(Young-Hyun Oh),정미경(Mi Kyoung Jung),김병직(Byungjick Kim2) 한국해군과학기술학회 2023 Journal of the KNST Vol.6 No.3

This study aimed to investigate the protective effects of a skin protection cream against aluminum chloride, a substance that can cause skin irritation and burns when exposed to the skin. After confirming the safety of the protective cream through skin sensitivity tests, we examined whether the cream could reduce the skin toxicity caused by aluminum chloride using a full-thickness cultured skin. The test results showed a significantly higher level of procollagen synthesis in the group where the skin protection cream was applied compared to the group exposed to aluminum chloride. Additionally, aluminum chloride was found to persist even after washing, but the protection cream inhibited its persistence. These results demonstrate that the skin protection cream can contribute to the prevention of occupational skin diseases among naval personnel and maintenance crew involved in tasks such as ship maintenance.

하수처리장 적용을 위한Semi-카플란 수차가 장착된 마이크로수력발전 시스템

채규정(Kyu Jung Chae),김동수(Dong Soo Kim),천경호(Kyung Ho Cheon),김원경(Won Kyoung Kim),김정연(Jung Yeon Kim),이철형(Chul Hyung Lee),박완순(Wan Soon Park) 大韓環境工學會 2013 대한환경공학회지 Vol.35 No.5

소수력발전은 하수처리장 에너지 자립을 위한 효과적인 대안이다. 본 연구는 유량변동이 크고 유효낙차가 낮은 중소형하수처리장(기흥레스피아) 적용을 위해 피치조절형 세미카플란(semi-kaplan) 마이크로수력발전의 적용 타당성을 평가하였다. 가변피치 semi-kaplan 수차는 유량조절을 위한 가이드베인은 생략하고 피치조절형 런너를 장착하여 기계적 결함은 줄이면서 유량변동이 큰 처리장에 특화된 기술이다. 마이크로수력발전 시스템은 설계조건(유량 0.35 m3/s, 유효낙차 4.7 m)에서 90.2%의 수차효율 달성이 가능하였고 발전용량은 13.4 kW로 산정되었다. 설비가동률 74%로 가동 시 연간 약 86.8 MWh 에너지 생산을 통해 2.1%의 에너지 자립이 가능하고 이는 연간 49톤의 CO₂ 감축효과와 맞먹는다. 경제성 평가결과 초기 건설공사비가 200,000,000원 이하인 경우에는 내부수익률은 6.1%, 순현가는 15,539,000원, 편익-비용률은 1.08, 투자회수년은 15.5년으로 경제성이 충분한 것으로 나타났다. Small scale hydropower is one of most attractive and cost-effective energy technologies for installation within sewage treatment plants. This study was conducted to evaluate the potential of a semi-kaplan micro-hydropower (MHP) system for application to sewage treatment plants with high flow fluctuations and a low head. The semi-kaplan MHP is equipped with an adjustable runner blade, and is without a guide vane, so as to reduce the incidence of mechanical problems. A MHP rating 13.4 kWp with a semi-kaplan turbine has been considered for Kiheung Respia sewage treatment plant, and this installation is estimated to generate 86.8 MWh of electricity annually, which is enough to supply electricity to over 25 households, and equivalent to an annual reduction of 49 ton CO₂. The semi-kaplan turbine showed a 90.2% energy conversion efficiency at the design flow rate of 0.35 m3/s and net head of 4.7 m, and was adaptable to a wide range of flow fluctuations. Through the MHP operation, approximately 2.1% of total electricity demand of Kiheung Respia sewage treatment plant will be achievable. Based on financial analysis, an exploiting MHP is considered economically acceptable with an internal rate of return of 6.1%, net present value of 15,539,000 Korean Won, benefit- cost ratio of 1.08, and payback year of 15.5, respectively, if initial investment cost is 200,000,000 Korean Won.

Obesity induced by high fat diet in Rhomboid family member 2 (Rhbdf2) KO mice

Sung-Jun Kim(Sung-Jun Kim),Seul Gi Park(Seul Gi Park),Young-Sub Byun(Young-Sub Byun),Eun-Kyoung Kim(Eun-Kyoung Kim),Sang-Mi Cho(Sang-Mi Cho),Harim Kim(Harim Kim),Young-Suk Won(Young-Suk Won),Hyoung-Ch 한국예방수의학회 2017 한국예방수의학회 학술대회자료집 Vol.2017 No.-

Unidirectional Magnon-Driven Domain Wall Motion Due to the Interfacial Dzyaloshinskii-Moriya Interaction

Kim, Kyoung-Whan,Lee, Seo-Won,Moon, Jung-Hwan,Go, Gyungchoon,Manchon, Auré,lien,Lee, Hyun-Woo,Everschor-Sitte, Karin,Lee, Kyung-Jin American Physical Society 2019 Physical Review Letters Vol.122 No.14

Protective Effect of Paulownia tomentosa Fruits in an Experimental Animal Model of Acute Lung Injury

Kim, Seong-Man,Ryu, Hyung Won,Kwon, Ok-Kyoung,Min, Jae-Hong,Park, Jin-Mi,Kim, Doo-Young,Oh, Sei-Ryang,Lee, Seung Jin,Ahn, Kyung-Seop,Lee, Jae-Won The Korean Society for Microbiology and Biotechnol 2022 한국미생물·생명공학회지 Vol.50 No.2

The fruits of Paulownia tomentosa (Thunb.) (PT) Steud. have been reported to exert a variety of biological activities. A previous study confirmed that compounds isolated from PT fruits (PTF) exerted anti-inflammatory effects on TNF-α-stimulated airway epithelial cells. However, there is no report on the protective effects of PTF on acute lung injury (ALI). Here, we examined the ameliorative effects of PTF in an experimental animal model of lipopolysaccharide (LPS)-induced ALI. In ALI mice, increased levels of inflammatory cell influx were confirmed in the lungs of mice, and an increase of microphage numbers, TNF-α, IL-6 and MCP-1 production and protein content were detected in mouse bronchoalveolar lavage fluid. However, these increases were significantly reversed with PTF pretreatment. In addition, PTF inhibited the increased expression of iNOS and COX-2 in the lungs of ALI mice. Furthermore, the upregulation of MAPK and NF-κB activation was decreased in the lungs of ALI mice by PTF. In the in vitro experiment, PTF pretreatment exerted an anti-inflammatory effect by inhibiting the secretion of nitric oxide, TNF-α and IL-6 in LPS-stimulated RAW264.7 macrophages. Collectively, these results indicated that PTF has ameliorative effects on airway inflammation in an experimental animal model of ALI.

Optimization of Hyaluronidase Inhibition Activity from Prunus davidiana (Carriere) Franch Fruit Extract Fermented by its Isolated Bacillus subtilis Strain SPF4211

( Won Baek Kim ),( So Hae Park ),( Kyoung Yoon Koo ),( Bo Ram Kim ),( Minji Kim ),( Heeseob Lee ) 한국미생물 · 생명공학회 2016 Journal of microbiology and biotechnology Vol.26 No.9

Strain SPF4211, having hyaluronidase (HAase) inhibition activity, was isolated from P. davidiana (Carriere) Franch fruit (PrDF) sugar extract. The phenotypic and biochemical properties based on 16S rDNA sequencing and an API 50 CHB kit suggested that the organism was B. subtilis. To optimize the HAase inhibition activity of PrDF extract by fermentation of strain SPF4211, a central composite design (CCD) was introduced based on three variables: concentration of PrDF extract (X1: 1-5%), amount of starter culture (X2: 1-5%), and fermentation time (X3: 0-7 days). The experimental data were fitted with quadratic regression equations, and the accuracy of the equations was analyzed by ANOVA. The statistical model predicted the highest HAase inhibition activity of 37.936% under the optimal conditions of X1 = 1%, X2 = 2.53%, and X3 = 7 days. The optimized conditions were validated by observation of an actual HAase inhibition activity of 38.367% from extract of PrDF fermented by SPF4211. These results agree well with the predicted model value.

Functional characterization of a bacterial expansin from Bacillus subtilis for enhanced enzymatic hydrolysis of cellulose

Kim, Eun Sil,Lee, Hee Jin,Bang, Won-Gi,Choi, In-Geol,Kim, Kyoung Heon Wiley Subscription Services, Inc., A Wiley Company 2009 Biotechnology and bioengineering Vol.102 No.5

<P>Expansin is a plant protein family that induces plant cell wall-loosening and cellulose disruption without exerting cellulose-hydrolytic activity. Expansin-like proteins have also been found in other eukaryotes such as nematodes and fungi. While searching for an expansin produced by bacteria, we found that the BsEXLX1 protein from Bacillus subtilis had a structure that was similar to that of a β-expansin produced by maize. Therefore, we cloned the BsEXLX1 gene and expressed it in Escherichia coli to evaluate its function. When incubated with filter paper as a cellulose substrate, the recombinant protein exhibited both cellulose-binding and cellulose-weakening activities, which are known functions of plant expansins. In addition, evaluation of the enzymatic hydrolysis of filter paper revealed that the recombinant protein also displayed a significant synergism when mixed with cellulase. By comparing the activity of a mixture of cellulase and the bacterial expansin to the additive activity of the individual proteins, the synergistic activity was found to be as high as 240% when filter paper was incubated with cellulase and BsEXLX1, which was 5.7-fold greater than the activity of cellulase alone. However, this synergistic effect was observed when only a low dosage of cellulase was used. This is the first study to characterize the function of an expansin produced by a non-eukaryotic source. Biotechnol. Bioeng. 2009;102: 1342–1353. © 2008 Wiley Periodicals, Inc.</P>