고온 초전도체의 국부�치 에너지에 따른 온도분포 해석

주민석,배준한,고태국,강연일 연세대학교 산업기술연구소 1994 논문집 Vol.26 No.1

The transient one-dimensional heat conduction equation in a high Tc bulk superconductor with an localized hot zone has been analyzed numerically. After the heater energy is introduced in a few miliseconds, the development of the normal zone and full quench time are calculated with respect to distance as a fuction of three parameters including : transport current, heater current, heating time. The analysis of this model is performed using finite difference method under modified adiabatic condition. The results of computer simulation are also presented in this paper. Full quench occurs when transport currents exceed 1.15[A] in given heater current and heating time. A temperature of superconductor rises abruptly in heating region when heater energy is increased. If heater energy is same, heating time is dominant factor for quench. Given heater energy, ohmic heat dissipation is dominant part for quench. But, heating energy is dominant part for quench than conduction. When heater energy is large, quench is not affected by transport currents.

사회복귀시설의 현황과 전망

황태연,이종국,고영,이주호,지성학 용인정신의학연구소 1997 용인정신의학보 Vol.4 No.1

흰쥐 난소에서 가지돌기세포 (dendritic cell) 및 큰포식세포의 특징과 분포양상

윤식,최연주,고서영,박선미,박봉수 대한해부학회 1997 Anatomy & Cell Biology Vol.30 No.1

Physicochemical Characteristics and Antioxidant Effects of Cooked-rice Added Foxtail Millet according to Cooking Method

Koan Sik Woo,Mi-Jung Kim,Hyun-Joo Kim,Eun-Yeong Sim,Jee Yeon Ko3,Byong Won Lee,Choon Ki Lee,Yong Hee Jeon,Byoung Kyu Lee 한국작물학회 2017 한국작물학회 학술발표대회 논문집 Vol.2017 No.-

2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

Hidden truth of truncal acne and the next generation retinoid

( Joo Yeon Ko ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.-

Functions (Mobility, Self-care, Social Ability) and Health-related Quality of Life in Children with Cerebral Palsy

Ko, Joo-Yeon,Lee, Suk-Min The Korean Society of Physical Therapy 2010 대한물리치료학회지 Vol.22 No.3

Purpose: The purpose of this study was to describe the functional (mobility, self-care, social ability) and health-related quality of life in children with cerebral palsy (CP). Methods: A cross- sectional survey of 202 children with CP, mean age $5.91{\pm}1.57$ years, was carried out using the Gross Motor Function Classification System (GMFCS), Gross Motor Function Measure (GMFM), Pediatric Evaluation of Disability Inventory (PEDI), and Child Health Questionnaire (CHQ). Results: The functional assessment of children with CP showed that a more severe GMFCS level was associated with lower functional abilities (p<0.05). The health-related quality of life assessment showed that psychosocial well-being was less impaired than physical well-being. The internal consistency of the three instruments was satisfactory (cronbach's ${\alpha}$>0.80). The three different scales were correlated from moderate to strong (r=0.44 to 0.92). It was also found that mobility, tone distribution, and the parents' education level exerted a significant effect on the quality of life of children with CP (p<0.05). Conclusion: These findings suggest that children with CP have reduced function and quality of life and these are influenced by various factors. However, planning and application of various task-oriented functional interventions to childhood CP may be useful.

DNA mismatch repair in Korean non-melanoma skin cancer patients

( Joo Yeon Ko ),( Minyoung Kim ),( Chang Hwa Song ),( Dong Seok Shin ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: The balance of several DNA mismatch repair (MMR) proteins exert both the repair and the damage response to exogenous DNA damage such as ultraviolet injury. Previously, MSH2, MSH6, MHL1 and PMS2 are differently expressed in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Objectives: This study was to investigate the correlation between MMR proteins and nonmelanoma skin cancer (NMSC). Methods: We performed an immunohistochemical (IHC) study of MSH2, MSH6, MHL1 and PSM2 in BCC, SCC and actinic keratosis (AK) patients, to demonstrate the role of these 4 MMR proteins in Korean NMSC patients. For stained samples are a score of 0, 1,2, or 3 reflected the staining intensity for the majority of the cells in the tumour. Results: Each 35 BCC, SCC and AK patients were included. The staining score of MSH-2 showed BCC>SCC>AK (1.9>1.8>1.6). The score of MSH6 are AK>BCC>SCC (2.8>2.6>2.2). MLH1 are AK>BCC>SCC (1.5>1.0>0.9). PMS2 SCC>AK>BCC (1.8>0.5>0.1). Conclusion: Our data point towards an expanded perspective of the importance of MMR proteins in the dysregulation of UV-induced tumorigenesis. Further larger and global studies are need to discover the significance of the dysregulated MMR protein expression in NMSC.

Loss of 5-hydroxymethylcytosine in Korean melanoma patients

( Joo Yeon Ko ),( Minyoung Kim ),( Seung Min Lee ),( Dong Seok Shin ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: Early detection of malignant melanoma is important for treating cutaneous melanoma. Using existing biomarkers like S-100, HMB45, and MART-1, some attempts to distinguish between benign nevi and melanoma has been experimented, but those biomarkers were considered to have lack of pathognomonic value for melanocytic malignancies. Recent studies have maintained their focus on the epigenetic mechanisms to certain characteristic features of cancer. Epigenetic marker, 5-hydroxymethylcytosine (5-hmC) has been to the fore as a novel biomarker in many cancers as well as melanoma Objectives: This study was to investigate the correlation between 5-hmC and melanoma in Korean patients Methods: We performed an immunohistochemical (IHC) study of 5-hmC in acral melanoma patients, to demonstrate the role of ‘loss of 5-hmC’ in recognizing higher malignant potential compared to benign acquired melanocytic nevus. Results: Thirty melanoma and 16 benign melanocytic nevus patients were included. 5-hmC levels were low in 27 (90%, 27/30) melanoma patients. However, no patients showed low level of 5-hmC staining. Conclusion: Our data suggest that loss of 5hmC could help early detection of melanoma in Korean patients. Later we propose that larger and global studies are need to discover the significance of loss of 5-hmC in melanoma patients.

Hidden truth of truncal acne and the next generation retinoid

( Joo Yeon Ko ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.1